ASAIO Journal最新文献_第10页

Predictors of Nonutilization of Ex Vivo Perfused Donor Heart Allografts. 体外灌注异体供体心脏移植不被利用的预测因素。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-08-01 Epub Date: 2025-01-16 DOI: 10.1097/MAT.0000000000002377

David Rekhtman, Michaela Asher, Amit Iyengar, Cindy Song, Noah Weingarten, Max Shin, John DePaolo, Samuel Kim, Marisa Cevasco, Pavan Atluri

{"title":"Predictors of Nonutilization of Ex Vivo Perfused Donor Heart Allografts.","authors":"David Rekhtman, Michaela Asher, Amit Iyengar, Cindy Song, Noah Weingarten, Max Shin, John DePaolo, Samuel Kim, Marisa Cevasco, Pavan Atluri","doi":"10.1097/MAT.0000000000002377","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002377","url":null,"abstract":"Despite the development of novel procurement technologies, an imbalance remains between the demand for and the availability of donor hearts. We aimed to identify donor characteristics predictive of nonutilization of hearts supported by ex vivo perfusion. A national database was used to identify ex vivo perfused hearts before September 30, 2023. Donors were stratified into cohorts of \"Used\" and \"Discarded\" based on final allocation. Logistic regressions were developed to identify predictors of nonutilization in both the ex vivo and non-ex vivo perfused hearts. Of 1,393 hearts supported with ex vivo perfusion, 154 (11%) were unused. Unused donors were older and had more diabetes and hypertension (p < 0.05). By multivariable logistic regression, reduced ejection fraction (7.10 [3.19-15.77], p < 0.001), coronary artery disease (6.27 [1.15-34.30], p = 0.034), and advanced age (3.25 [2.02-5.21], p < 0.001) were predictors of discard. Elevated body mass and prolonged ischemic times were only predictive of discard in the non-ex vivo perfused cohort. Among procured donor hearts supported by ex vivo perfusion, poor heart function, and donor comorbidities were identified as predictors of nonutilization. Increased appreciation for the role of these variables on post-transplantation outcomes will allow for the development of cost-effective strategies to expand the donor pool.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":"71 8","pages":"637-643"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor Regarding Enhancing Survival Prediction After Venoarterial Extracorporeal Membrane Oxygenation Using Machine Learning. 关于使用机器学习增强静脉体外膜氧合后生存预测的致编辑信。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-08-01 DOI: 10.1097/MAT.0000000000002524

Jiaye Wang, Jin Peng, Zhifeng Liang, Guoying Wang

引用次数: 0

Extracorporeal Membranous Oxygenation Associated With Tracheal Procedures: An Extracorporeal Life Support Organization (ELSO) Registry Analysis. 与气管手术相关的体外膜性氧合：体外生命支持组织（ELSO）注册分析。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-08-01 Epub Date: 2025-02-07 DOI: 10.1097/MAT.0000000000002389

Yota Suzuki, Ian G Christie, Ernest G Chan, John Ryan, Matthew J Schuchert, Holt N Murray, Masashi Furukawa, Pablo G Sanchez

{"title":"Extracorporeal Membranous Oxygenation Associated With Tracheal Procedures: An Extracorporeal Life Support Organization (ELSO) Registry Analysis.","authors":"Yota Suzuki, Ian G Christie, Ernest G Chan, John Ryan, Matthew J Schuchert, Holt N Murray, Masashi Furukawa, Pablo G Sanchez","doi":"10.1097/MAT.0000000000002389","DOIUrl":"10.1097/MAT.0000000000002389","url":null,"abstract":"Extracorporeal membrane oxygenation (ECMO) has been primarily used for respiratory and circulatory failure, but its airway-related use has not been investigated well. Tracheal procedures are a situation when ECMO could be used to support patients during anticipated difficult airway management. The Extracorporeal Life Support Organization registry was queried for adult patients treated with ECMO in 2010-2022 during the same admission with types of tracheal procedures. Tracheal procedures were divided into surgical procedure and bronchoscopic procedure groups, and the survival rate was analyzed for each procedural type. Two-hundred sixty-nine patients met the inclusion criteria (64 surgical procedures and 205 bronchoscopic procedures), and 173 (64.3%) patients survived to discharge. Among the surgical procedures, tracheal resection was most performed (30 patients; 46.9%) and was associated with a high survival rate to discharge (86.7%; p = 0.003) compared with airway reconstruction (57.1%) and airway injury repair (46.2%). In bronchoscopic procedure, tracheal stent had favorable survival (76.1%; p = 0.004), whereas tumor debulking was associated with poor prognosis (48.3%; p = 0.006). Hemorrhagic complications were seen in 70 (26.0%) patients and were associated with a worse survival rate (58.6%; p < 0.001). Among them, surgical site bleeding was seen in 35 (13.0%) patients and was also associated with worse survival (42.9%; p = 0.007).","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":"675-681"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calculation of Absolute Blood Volume Using Intermittent Infusion Hemodiafiltration. 间歇输注血液滤过法计算绝对血容量。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-08-01 DOI: 10.1097/MAT.0000000000002522

Tomoyuki Tanaka, Tomohiro Matsui, Keigo Imagawa, Shunri Taniguchi, Masafumi Kitakaze

{"title":"Calculation of Absolute Blood Volume Using Intermittent Infusion Hemodiafiltration.","authors":"Tomoyuki Tanaka, Tomohiro Matsui, Keigo Imagawa, Shunri Taniguchi, Masafumi Kitakaze","doi":"10.1097/MAT.0000000000002522","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002522","url":null,"abstract":"The absolute blood volume of dialysis patients at the start of treatment can be calculated using a method that combines continuous relative blood volume measurement and dialysate infusion. In this study, we applied this method to patients undergoing intermittent infusion hemodiafiltration. The initial absolute blood volume was measured based on the relative blood volume changes observed during each of the five intermittent dialysate infusions (dilutions). Initial absolute blood volumes, determined via the first to fifth dilutions, were 4,288 ± 900, 4,377 ± 1,476, 4,170 ± 1,037, 4,009 ± 951, and 3,871 ± 929 ml (specific volumes were 79.5 ± 12.5, 81.2 ± 20.9, 78.2 ± 15.8, 75.1 ± 13.4, and 72.7 ± 13.9 ml/kg). The final absolute blood volumes were 3,813 ± 857, 3,953 ± 1,430, 3,764 ± 1,034, 3,611 ± 919, and 3,488 ± 908 ml (specific volumes were 71.1 ± 11.5, 73.0 ± 20.4, 70.3 ± 15.5, 67.3 ± 12.7, and 65.2 ± 13.2 ml/kg). The initial absolute blood volume measured using the fifth dilution was significantly lower than that of the first dilution (p < 0.05). The use of intermittent infusion hemodiafiltration, along with relative blood volume measurement, is an easy method for determining absolute blood volume.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Advanced Heart Failure Duration on Left Ventricular Functional Improvement After Left Ventricular Assist Device Implantation. 晚期心力衰竭持续时间对左心室辅助装置植入后左心室功能改善的影响。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-31 DOI: 10.1097/MAT.0000000000002474

Ruben Crespo-Diaz, Benjamin Sun, William McDonald, Carrie Weaver, Michael Samara, Peter M Eckman, Katarzyna Hryniewicz

{"title":"Impact of Advanced Heart Failure Duration on Left Ventricular Functional Improvement After Left Ventricular Assist Device Implantation.","authors":"Ruben Crespo-Diaz, Benjamin Sun, William McDonald, Carrie Weaver, Michael Samara, Peter M Eckman, Katarzyna Hryniewicz","doi":"10.1097/MAT.0000000000002474","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002474","url":null,"abstract":"Left ventricular recovery (LV) in patients with advanced heart failure (HF) supported by a durable left ventricular assist device (LVAD) is uncommon but clinically significant. There is limited understanding on the timing of LV recovery in relation to LVAD implantation. A total of 383 HF patients who underwent LVAD implantation were evaluated for LV functional improvement defined as an absolute increase in left ventricular ejection fraction (LVEF) of greater than or equal to 20% post-LVAD placement. Out of 383 LVAD patients, 39 (10.1%) demonstrated significant LV improvement. Among these, 25 (64%) patients had received LVAD less than or equal to 1 year of HF diagnosis, whereas 14 (36%) patients were implanted greater than 1 year from HF diagnosis. No significant differences in baseline imaging or hemodynamics were found between these two groups. The timing of LVAD implantation and time from LVAD to LVEF improvement was not associated with 5 year outcomes. Survival, free from HF relapse or transplant was 59% in the less than or equal to 1 year and 46% in greater than 1 year HF duration groups (p = 0.83). Thus, LV functional improvement can occur across a broad spectrum of HF duration, suggesting that the potential for recovery is not limited to those with newly diagnosed disease.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Liver Transplantation After Ex-Vivo Normothermic Machine Perfusion: A No-Recooling Technique With Room-Temperature Albumin Flush. 离体恒温机器灌注后肝移植：一种无冷却的室温白蛋白冲洗技术。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-31 DOI: 10.1097/MAT.0000000000002516

Salvatore Gruttadauria, Ivan Vella, Sergio Calamia, Sergio Li Petri, Caterina Accardo, Duilio Pagano, Fabrizio di Francesco

引用次数: 0

Clarifying Interpretability and Real-World Application of Machine Learning-Based Prognostic Models in Extracorporeal Membrane Oxygenation. 澄清基于机器学习的预测模型在体外膜氧合中的可解释性和实际应用。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-31 DOI: 10.1097/MAT.0000000000002525

Albert Leng, Sung-Min Cho

引用次数: 0

Study-Level Bias May Influence Bleeding Prevalence Estimates in Neonatal and Pediatric Extracorporeal Membrane Oxygenation. 研究水平偏差可能影响新生儿和儿童体外膜氧合出血患病率估计。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-31 DOI: 10.1097/MAT.0000000000002526

Patrick M Wieruszewski, Jamel P Ortoleva

引用次数: 0

Partial Removal of Mechanical Aortic Valve to Enable Direct Transcatheter Valve Implantation During Left Ventricular Assist Device Placement. 在左心室辅助装置放置期间，部分去除机械主动脉瓣以实现直接经导管瓣膜植入。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-29 DOI: 10.1097/MAT.0000000000002518

Anika Nagel, Fadi Al Radwan, Axel Unbehaun, Evgenij Potapov, Volkmar Falk, Miralem Pasic, Simon Sündermann, Pia Lanmüller

引用次数: 0

Global Survey of Extracorporeal Membrane Oxygenation Transport Programs: Variability in Team Composition, Training, and Capabilities. 体外膜氧合输送项目的全球调查：团队组成、训练和能力的可变性。

IF 2.3 3区医学

ASAIO Journal Pub Date : 2025-07-29 DOI: 10.1097/MAT.0000000000002515

Adam L Gottula, Lauren Gillespie, Michael Lauria, Christopher R Shaw, Ella Purington, Brittney Bernardoni, Andrew Cathers, Kolby Kolbet, Marcus Rudolph, Alberto Lucchini, Per Bredmose, Michael Frakes, Jenelle Badulak, Kyle Danielson, Melissa Ann Vogelsong, Dinis Reis Miranda, Guglielmo Imbriaco, Jeffrey D DellaVolpe, William R Hinckley, Brian Burns, Jason A Bartos, Cindy H Hsu, Christine Brent, Bennett H Lane

{"title":"Global Survey of Extracorporeal Membrane Oxygenation Transport Programs: Variability in Team Composition, Training, and Capabilities.","authors":"Adam L Gottula, Lauren Gillespie, Michael Lauria, Christopher R Shaw, Ella Purington, Brittney Bernardoni, Andrew Cathers, Kolby Kolbet, Marcus Rudolph, Alberto Lucchini, Per Bredmose, Michael Frakes, Jenelle Badulak, Kyle Danielson, Melissa Ann Vogelsong, Dinis Reis Miranda, Guglielmo Imbriaco, Jeffrey D DellaVolpe, William R Hinckley, Brian Burns, Jason A Bartos, Cindy H Hsu, Christine Brent, Bennett H Lane","doi":"10.1097/MAT.0000000000002515","DOIUrl":"https://doi.org/10.1097/MAT.0000000000002515","url":null,"abstract":"Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary support associated with improved survival in severe respiratory failure and refractory cardiac arrest. Extracorporeal membrane oxygenation is highly specialized and resource-intensive; high-volume ECMO centers demonstrate improved outcomes, supporting the creation of regionalized care models. As such, the role of critical care transport medicine (CCTM) is vital. Given limited prior analysis, we aimed to descriptively review ECMO transport processes globally. A 27 item survey addressing team composition, training, and transport capabilities was distributed to 16 transport organizations in eight countries. If available, ECMO transport protocols were reviewed. Fourteen ECMO programs responded from six countries (87.5% response rate). Most programs (78.6%) offer ground, 71.4% offer rotary-wing, and 50% offer fixed-wing transport. A minority (28.6%) provided all transport modes. Nearly half (42.9%) of programs did not require a separate ECMO team. A physician was present in 57.1% and a perfusionist/ECMO specialists in 71.4% of transport teams, respectively. All programs required initial team ECMO training. Critical care transport medicine teams are essential for enabling ECMO access. There is significant variability in team composition, capabilities, and transport modality, but training requirements are seen across programs. Further study should align best practices for interfacility transport of ECMO patients.","PeriodicalId":8844,"journal":{"name":"ASAIO Journal","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144727168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0