Utilization and Outcomes of Temporary Percutaneous Right Ventricular Assist Devices in Cardiogenic Shock.

IF 3.1 3区 医学 Q2 ENGINEERING, BIOMEDICAL
ASAIO Journal Pub Date : 2025-05-01 Epub Date: 2024-11-13 DOI:10.1097/MAT.0000000000002348
Kevin John John, Jaime Hernandez-Montfort, Manreet K Kanwar, Song Li, Arthur Reshad Garan, Shashank S Sinha, Jacob Abraham, Saraschandra Vallabhajosyula, Borui Li, Qiuyue Kong, Paavni Sangal, Daniel Burkhoff, Navin K Kapur
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Abstract

Acute right ventricular failure (RVF) is a common finding in cardiogenic shock (CS), yet the optimal method of supporting the failing RV remains unclear. This study aimed to describe CS patients receiving percutaneous right ventricular assist devices (pRVADs) using the multicenter Cardiogenic Shock Working Group (CSWG) registry. Among 6,201 patients with CS, 152 (2.4%) received pRVADs, with ProtekDuo and Impella RP being used in 71% and 29% of cases, respectively. The average age of this group was 58.5 years, with a higher proportion of men (66.4%). Heart failure-associated CS (HF-CS) was observed in 48% of patients, while myocardial infarction-associated CS (MI-CS) was seen in 27% (HF-CS versus MI-CS: 52.8% vs. 21.3% for ProtekDuo; 36.4% vs. 40.9% for Impella RP; p = 0.01). The overall in-hospital mortality rate was 54.6%, bleeding complications were more prevalent among ProtekDuo recipients (64.8% vs. 43.2%, p = 0.008), whereas Impella RP recipients had shorter hospital stays (20.4 ± 18.7 vs. 41.9 ± 31.5 days, p < 0.001). ProtekDuo was more commonly used in patients with HF-CS and was associated with higher rates of bleeding and longer hospital stays compared with Impella RP, although overall mortality was similar. Further investigation is required to determine the ideal timing and clinical conditions warranting pRVAD deployment in CS.

临时经皮右心室辅助装置在心源性休克中的应用和效果。
急性右心室衰竭(RVF)是心源性休克(CS)的常见发现,但支持衰竭右心室的最佳方法尚不清楚。本研究旨在通过多中心心源性休克工作组(CSWG)登记来描述接受经皮右心室辅助装置(pRVADs)的CS患者。在6201例CS患者中,152例(2.4%)接受了pRVADs, ProtekDuo和Impella RP分别占71%和29%。本组平均年龄为58.5岁,男性比例较高(66.4%)。48%的患者出现心力衰竭相关CS (HF-CS), 27%的患者出现心肌梗死相关CS (MI-CS) (HF-CS vs MI-CS: ProtekDuo组52.8% vs 21.3%;36.4% vs. Impella RP 40.9%;P = 0.01)。总体住院死亡率为54.6%,出血并发症在ProtekDuo患者中更为普遍(64.8%对43.2%,p = 0.008),而Impella RP患者住院时间较短(20.4±18.7对41.9±31.5天,p < 0.001)。ProtekDuo更常用于HF-CS患者,与Impella RP相比,它与更高的出血率和更长的住院时间相关,尽管总体死亡率相似。需要进一步的研究来确定在CS中部署pRVAD的理想时机和临床条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ASAIO Journal
ASAIO Journal 医学-工程:生物医学
CiteScore
6.60
自引率
7.10%
发文量
651
审稿时长
4-8 weeks
期刊介绍: ASAIO Journal is in the forefront of artificial organ research and development. On the cutting edge of innovative technology, it features peer-reviewed articles of the highest quality that describe research, development, the most recent advances in the design of artificial organ devices and findings from initial testing. Bimonthly, the ASAIO Journal features state-of-the-art investigations, laboratory and clinical trials, and discussions and opinions from experts around the world. The official publication of the American Society for Artificial Internal Organs.
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