Beilstein Journal of Nanotechnology最新文献

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Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in Cd x Zn1- x O composite thin films. Cd x Zn1- x O复合薄膜中B1相从高压B2相中回收CdO纳米颗粒
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-17 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.43
Arkaprava Das, Marcin Zając, Carla Bittencourt
{"title":"Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in Cd <i><sub>x</sub></i> Zn<sub>1-</sub> <i><sub>x</sub></i> O composite thin films.","authors":"Arkaprava Das, Marcin Zając, Carla Bittencourt","doi":"10.3762/bjnano.16.43","DOIUrl":"https://doi.org/10.3762/bjnano.16.43","url":null,"abstract":"<p><p>This study investigates the recovery of the B1 phase from the high-pressure B2 phase, at atmospheric pressure, in cadmium oxide (CdO) nanoparticles incorporated within sol-gel synthesized Cd <i><sub>x</sub></i> Zn<sub>1-</sub> <i><sub>x</sub></i> O (<i>x</i> = 0.40) composite thin films. The recovery process is investigated using electronic excitations as an effective tool. Exposure to 120 MeV silver ion irradiation results in the complete amorphization of the B2 phase in CdO nanoparticles, while the crystalline hexagonal wurtzite phase of zinc oxide (ZnO) remains intact. In contrast, 80 MeV oxygen ion irradiation preserves the B2 phase and facilitates the reemergence of the B1 phase. The partial damage caused by electronic energy loss during oxygen ion irradiation in the willemite Zn<sub>2</sub>SiO<sub>4</sub> phase is identified as a trigger for the B1 to B2 phase transformation in CdO nanoparticles, enabling the recovery of the B1 phase. The diminishing local pressure exerted by the Zn<sub>2</sub>SiO<sub>4</sub> phase on CdO nanoparticles during oxygen ion irradiation leads to the coexistence of both B1 and B2 phases. X-ray absorption near-edge spectra (XANES) reveal minimal changes in the intensity of the spike-like Zn <i>L</i> <sub>3,2</sub> pre-edge feature associated with the Zn<sub>2</sub>SiO<sub>4</sub> phase under oxygen ion irradiation, while it entirely disappears with silver ion irradiation, confirming the amorphization of the Zn<sub>2</sub>SiO<sub>4</sub> phase. Complementary observations from X-ray photoelectron spectroscopy (XPS), specifically O 1s and Si 2p peaks in XPS spectra, support these findings. Additionally, the track diameter in CdO subjected to 120 MeV silver ion irradiation is calculated to be approximately 8 nm using an inelastic thermal spike simulation code. This study elucidates the intriguing reappearance of the B1 phase under oxygen ion irradiation and highlights the radiation stability of the B2 phase through diverse characterization techniques, demonstrating the potential reversibility of the B1 to B2 phase transformation induced by ion irradiation.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"551-560"},"PeriodicalIF":2.6,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus. 碳丝网印刷电极上功能化金纳米花:一种生物感应甲型H1N1流感病毒血凝素蛋白的电化学平台。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-16 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.42
Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam
{"title":"Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus.","authors":"Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam","doi":"10.3762/bjnano.16.42","DOIUrl":"https://doi.org/10.3762/bjnano.16.42","url":null,"abstract":"<p><p>An electrochemical biosensor based on modified carbon screen-printed electrodes was developed for the detection of hemagglutinin of influenza A H1N1 virus (H1). Gold nanoflowers were electrodeposited on the electrode to increase conductivity and surface area. The electrochemical signal was amplified by functionalization of the gold nanoflowers with 4-aminothiophenol, which resulted in a 100-fold decrease of the charge transfer resistance due to a tunneling effect. Subsequently, monoclonal antibodies against H1 were immobilized on the surface via covalent amide bond formation, followed by blocking with bovine serum albumin to minimize nonspecific hydrophobic binding. The electrodes were characterized by cyclic voltammetry and electrochemical impedance spectroscopy experiments in the presence of [Fe(CN)<sub>6</sub>]<sup>3-/4-</sup>. Differential pulse voltammetry was used to measure the change in current across the electrode as a function of H1 concentration. This was performed on a series of samples of artificial saliva containing H1 protein in a clinically relevant concentration range. In these experiments, the biosensor showed a limit of detection of 19 pg/mL. Finally, the biosensor platform was coupled to an automated microfluidics system, and no significant decrease of the electrochemical signal was observed.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"540-550"},"PeriodicalIF":2.6,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex. 利用钯β-酮酯配合物的电子束直接写入纳米结构。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-15 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.41
Chinmai Sai Jureddy, Krzysztof Maćkosz, Aleksandra Butrymowicz-Kubiak, Iwona B Szymańska, Patrik Hoffmann, Ivo Utke
{"title":"Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex.","authors":"Chinmai Sai Jureddy, Krzysztof Maćkosz, Aleksandra Butrymowicz-Kubiak, Iwona B Szymańska, Patrik Hoffmann, Ivo Utke","doi":"10.3762/bjnano.16.41","DOIUrl":"https://doi.org/10.3762/bjnano.16.41","url":null,"abstract":"<p><p>Gas-assisted focused electron beam-induced deposition (FEBID) as a direct, minimally invasive 3D nanopatterning tool offers many advantages in making nanostructures with complex shapes and novel compositions for evolving nanotechnological applications. In this work, structures were nanoprinted using a fluorine-free β-ketoesterate complex, bis(<i>tert</i>-butylacetoacetate)palladium(II), [Pd(tbaoac)<sub>2</sub>]. The internal nanostructure and composition of the deposits were determined, and possible volatile products produced under electron-induced dissociation, explaining the composition, are investigated. A method to eliminate the residual gas contamination during FEBID was implemented. [Pd(tbaoac)<sub>2</sub>] contains large organic ligands and only about 5 atom % palladium in the pristine molecule, yet the obtained palladium content in the deposits amounts to around 30 atom %. This translates to an exceptional removal efficiency of about 90% for the ligand-constituting elements carbon and oxygen through electron-induced dissociation and desorption mechanisms. Comparison with other precursors confirms that the β-ketoesterate family has the highest ligand removal percentage and constitutes thus an interesting model chemistry for further high-metal-content FEBID studies. The possibility of growing nanopillars makes this complex a promising precursor for nanoprinting 3D structures with finely focused electron beams.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"530-539"},"PeriodicalIF":2.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zeolite materials with Ni and Co: synthesis and catalytic potential in the selective hydrogenation of citral. 含镍、钴的沸石材料的合成及其在柠檬醛选择性加氢中的催化潜力。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-14 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.40
Inocente Rodríguez-Iznaga, Yailen Costa Marrero, Tania Farias Piñeira, Céline Fontaine, Lexane Paget, Beatriz Concepción Rosabal, Arbelio Penton Madrigal, Vitalii Petranovskii, Gwendoline Lafaye
{"title":"Zeolite materials with Ni and Co: synthesis and catalytic potential in the selective hydrogenation of citral.","authors":"Inocente Rodríguez-Iznaga, Yailen Costa Marrero, Tania Farias Piñeira, Céline Fontaine, Lexane Paget, Beatriz Concepción Rosabal, Arbelio Penton Madrigal, Vitalii Petranovskii, Gwendoline Lafaye","doi":"10.3762/bjnano.16.40","DOIUrl":"https://doi.org/10.3762/bjnano.16.40","url":null,"abstract":"<p><p>Zeolitic materials incorporating mono- and bimetallic systems of nickel and cobalt were obtained from natural zeolite modified with Ni<sup>2+</sup> and Co<sup>2+</sup> chloride solutions through traditional ion exchange (IE) and impregnation (Imp) processes. Special attention was given to analyzing the cationic and anionic composition of the resulting materials. The catalytic potential was evaluated in the selective hydrogenation of citral, focused on the formation of unsaturated alcohols. The IE process replaced mainly Ca<sup>2+</sup> and Na<sup>+</sup> with Ni<sup>2+</sup> and Co<sup>2+</sup> cations in the zeolite phases (clinoptilolite and mordenite mix), while Imp resulted in higher metal content (2.0-2.7%) but retained significant amounts of chloride (1.9-3.8%), as confirmed by XRD and temperature-programmed reduction. The materials prepared by IE had negligible chloride content (0.02-0.07%), and their specific surface areas (138-146 m<sup>2</sup>/g) were greater than those of the materials obtained by Imp (54-67 m<sup>2</sup>/g). The bimetallic systems exhibited enhanced reducibility of the Co<sup>2+</sup> and Ni<sup>2+</sup> isolated cations, attributed to synergistic interactions that weakened the cation-framework binding. Catalytic activity tests showed that nickel species were primarily responsible for citronellal formation. Among all materials, the bimetallic CoNi<sub>IE</sub> catalyst, prepared by IE, was the only one to produce unsaturated alcohols, suggesting that synergistic Ni-Co interactions played a role in their formation.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"520-529"},"PeriodicalIF":2.6,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12018909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Water in nanoporous hexagonal boron nitride nanosheets: a first-principles study. 纳米多孔六方氮化硼纳米片中的水:第一性原理研究。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-11 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.39
Juliana A Gonçalves, Ronaldo J C Batista, Marcia C Barbosa
{"title":"Water in nanoporous hexagonal boron nitride nanosheets: a first-principles study.","authors":"Juliana A Gonçalves, Ronaldo J C Batista, Marcia C Barbosa","doi":"10.3762/bjnano.16.39","DOIUrl":"https://doi.org/10.3762/bjnano.16.39","url":null,"abstract":"<p><p>Nanoporous membranes are being explored as efficient materials for water filtration and desalination applications. In this study, we analyzed the behavior of pores within a freestanding hexagonal boron nitride (<i>h</i>-BN) monolayer in contact with water molecules. Our investigation revealed that triangular and rhombic pores induce wrinkles in non-deposited <i>h</i>-BN monolayers because of the repulsion between hydrogen orbitals at their 60° vertices. We found that the addition of N-H or B-H pairs at 60° vertices mitigates these out-of-plane deformations. Surprisingly, the stability of triangular pores with N-H termination is significantly increased by the addition of B-H pairs, whereas the stability of triangular pores with B-H termination is decreased by the addition of N-H pairs, indicating a distinct evolution of the pore shape based on the initial edge termination. Furthermore, we observed that the combination of H and OH is more effective in stabilizing the edges of rhombic pores compared to using only H atoms, whereas the opposite is true for small triangular pores that cannot accommodate the ·OH radical. Our findings also demonstrate that rhombic pores have a high affinity for water absorption, much higher than that of triangular pores. This suggests that the type of pore can significantly alter the hydrophobicity of <i>h</i>-BN and influence water flow through the membrane. Additionally, we observed that water molecules tend to form hydrogen bonds with the N-H-terminated surface in rhombic pores, but not with the B-N-terminated surface, potentially leading to asymmetries in water flow through the pore area. Overall, our study provides valuable insights into the interaction between nanoporous <i>h</i>-BN membranes and water.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"510-519"},"PeriodicalIF":2.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
N2 +-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films. 氮注入诱导溅射钼薄膜结构、形态、光学和电学特性的裁剪。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-04-01 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.38
Usha Rani, Kafi Devi, Divya Gupta, Sanjeev Aggarwal
{"title":"N<sub>2</sub> <sup>+</sup>-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films.","authors":"Usha Rani, Kafi Devi, Divya Gupta, Sanjeev Aggarwal","doi":"10.3762/bjnano.16.38","DOIUrl":"10.3762/bjnano.16.38","url":null,"abstract":"<p><p>Molybdenum (Mo) thin films have extensive applications in energy storage devices and photovoltaic solar cells because of their remarkable thermal stability, high melting point, and chemical inertness. In the present study, Mo thin films of different thicknesses (150, 200, 250, and 300 nm) have been deposited on Si(100) substrates via radio frequency sputtering in an argon atmosphere at room temperature. Some of these films have been implanted with 1 × 10<sup>17</sup> N<sub>2</sub> <sup>+</sup>·cm<sup>-2</sup> at 30 keV using a current density of 4 µA·cm<sup>-2</sup>. Surface morphology and structural, optical, and electrical properties of the as-deposited and implanted Mo thin films have been systematically investigated. The crystallinity of Mo thin films is enhanced with increasing thickness of the as-deposited films. This pattern persists with film thickness even after N<sub>2</sub> <sup>+</sup> implantation. After implantation, crystallinity decreases relative to as-deposited films with the same nominal thickness. The AFM analysis reveals that RMS roughness increases with the thickness of Mo films. Optical studies using spectroscopic ellipsometry reveal a significant increase in absorbance and reflectance in as-deposited and N<sub>2</sub> <sup>+</sup>-implanted films. Electrical investigations show that the conductivity increases with film thickness in both as-deposited and implanted films. The conductivity decreases for the same nominal film thickness after implantation.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"495-509"},"PeriodicalIF":2.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring. 用于硅纳米结构的微波耦合等离子体超低能ECR离子源性能优化。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.37
Joy Mukherjee, Safiul Alam Mollick, Tanmoy Basu, Tapobrata Som
{"title":"Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring.","authors":"Joy Mukherjee, Safiul Alam Mollick, Tanmoy Basu, Tapobrata Som","doi":"10.3762/bjnano.16.37","DOIUrl":"10.3762/bjnano.16.37","url":null,"abstract":"<p><p>This paper presents a comprehensive optimization of key parameters for generating ion beams in a microwave-coupled plasma-based ultralow-energy electron cyclotron resonance ion source, generally used for nanostructuring solid surfaces. The investigation focuses on developing, accelerating, and extracting Ar ions from a magnetron-coupled plasma cup utilizing a three-grid ion extraction composed of molybdenum. The study systematically examines the dependence of ion beam current on critical parameters, such as gas pressure, magnetron power, extraction voltage, and ion energies. The Gaussian nature of the beam profile is scrutinized and elucidated within the context of grid extraction-based ion sources. Plasma physics principles are employed to interpret the observed variations in the beam current with various parameters. The optimized beam current is used to investigate the inert ion-induced nanopatterning of silicon surfaces, at various ion fluences and incidence angles. The pre- and post-bombardment changes in optical properties, resulting from nanopatterned surfaces, are investigated using UV-vis reflectivity measurements and correlated with the dimensions of the nanopatterns. This manuscript highlights the potential applications arising from these findings, emphasizing the transformative impact of nanopatterning through low-energy inert ions.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"484-494"},"PeriodicalIF":2.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of adsorbate-substrate interaction on nanostructured thin films growth during low-pressure condensation. 低压冷凝过程中吸附物-基质相互作用对纳米结构薄膜生长的影响。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-03-28 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.36
Alina V Dvornichenko, Vasyl O Kharchenko, Dmitrii O Kharchenko
{"title":"Impact of adsorbate-substrate interaction on nanostructured thin films growth during low-pressure condensation.","authors":"Alina V Dvornichenko, Vasyl O Kharchenko, Dmitrii O Kharchenko","doi":"10.3762/bjnano.16.36","DOIUrl":"10.3762/bjnano.16.36","url":null,"abstract":"<p><p>We discuss effects of elastic adsorbate-substrate interactions in processes of nanostructuring of thin films during low-pressure condensation in the framework of theoretical approaches and numerical simulations. It will be shown that an increase in the elastic interaction strength induces first-order transitions and pattern formation. We simulate deposition on one- and multicomponent substrates with different strengths of adsorbate-substrate interactions. We will show that an increase in the strength of adsorbate-substrate interactions stimulates the formation of stable surface structures during deposition, which leads to an increase in its coverage and the formation of a smaller number of adsorbate islands of larger size. At elevated adsorption rates, an increase in adsorbate-substrate interactions results in the transformation of the surface morphology and the formation of percolating adsorbate structures. Deposition onto multicomponent substrates leads to the formation of a stationary surface morphology with an elevated number of adsorbate islands of smaller size, compared to one-component substrates. This study provides a deep insight into the peculiarities of nanostructured thin films' growth in low-pressure systems with different adsorbate-substrate bonding.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"473-483"},"PeriodicalIF":2.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment. 合成聚合物辅助反义寡核苷酸递送:精准疾病治疗的靶向方法。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.34
Ana Cubillo Alvarez, Dylan Maguire, Ruairí P Brannigan
{"title":"Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment.","authors":"Ana Cubillo Alvarez, Dylan Maguire, Ruairí P Brannigan","doi":"10.3762/bjnano.16.34","DOIUrl":"10.3762/bjnano.16.34","url":null,"abstract":"<p><p>This review explores the recent advancements in polymer-assisted delivery systems for antisense oligonucleotides (ASOs) and their potential in precision disease treatment. Synthetic polymers have shown significant promise in enhancing the delivery, stability, and therapeutic efficacy of ASOs by addressing key challenges such as cellular uptake, endosomal escape, and reducing cytotoxicity. The review highlights key studies from the past decade demonstrating how these polymers improve gene silencing efficiencies, particularly in cancer and neurodegenerative disease models. Despite the progress achieved, barriers such as immunogenicity, delivery limitations, and scalability still need to be overcome for broader clinical application. Emerging strategies, including stimuli-responsive polymers and advanced nanoparticle systems, offer potential solutions to these challenges. The review underscores the transformative potential of polymer-enhanced ASO delivery in personalised medicine, emphasising the importance of continued innovation to optimise ASO-based therapeutics for more precise and effective disease treatments.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"435-463"},"PeriodicalIF":2.6,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of additives on the synthesis efficiency of nanoparticles by laser-induced reduction. 添加剂对激光诱导还原纳米颗粒合成效率的影响。
IF 2.6 4区 材料科学
Beilstein Journal of Nanotechnology Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.35
Rikuto Kuroda, Takahiro Nakamura, Hideki Ina, Shuhei Shibata
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