Australasian Journal of Dermatology最新文献

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The Rintala Advanced Modification (RAM) Flap: A Novel Technique for Off-Centre Nasal Reconstruction Rintala高级改良(RAM)皮瓣:一种偏中心鼻部重建的新技术。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-06-25 DOI: 10.1111/ajd.70169
Ramy Awadalla, Derek Davies
{"title":"The Rintala Advanced Modification (RAM) Flap: A Novel Technique for Off-Centre Nasal Reconstruction","authors":"Ramy Awadalla,&nbsp;Derek Davies","doi":"10.1111/ajd.70169","DOIUrl":"10.1111/ajd.70169","url":null,"abstract":"<p>The traditional Rintala flap is associated with visible forehead scarring and glabellar deformities. We describe the Rintala Advanced Modification (RAM) flap, a novel technique that restricts the flap below the eyebrow line and employs asymmetric Burow's triangles for off-centre defects. Based on 20 patients with nasal basal cell and squamous cell carcinomas, the RAM flap demonstrates superior aesthetic outcomes with no glabellar complications or flap tip necrosis.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"353-359"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.70169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appropriate Use of Mohs Micrographic Surgery: A Survey of Australasian Mohs Dermatologists 适当使用莫氏显微摄影术:澳大利亚莫氏皮肤科医生调查。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-05-07 DOI: 10.1111/ajd.70130
Edmund Wee, Ludi Ge, Amit Verma, Timothy Gilbert Elliott, Ernest Tan
{"title":"Appropriate Use of Mohs Micrographic Surgery: A Survey of Australasian Mohs Dermatologists","authors":"Edmund Wee,&nbsp;Ludi Ge,&nbsp;Amit Verma,&nbsp;Timothy Gilbert Elliott,&nbsp;Ernest Tan","doi":"10.1111/ajd.70130","DOIUrl":"10.1111/ajd.70130","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"364-369"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Narrative Review of the Factors Impacting Solid Organ Transplant Recipient Participation in Skin Cancer Screening 影响实体器官移植受者参与皮肤癌筛查的因素综述。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-05-04 DOI: 10.1111/ajd.70134
Will Swansson, Alvin H. Chong
{"title":"A Narrative Review of the Factors Impacting Solid Organ Transplant Recipient Participation in Skin Cancer Screening","authors":"Will Swansson,&nbsp;Alvin H. Chong","doi":"10.1111/ajd.70134","DOIUrl":"10.1111/ajd.70134","url":null,"abstract":"<p>Solid organ transplant recipients (SOTRs) are at a significantly elevated risk of cutaneous malignancy due to the requirement for lifelong immunosuppressive medications. Regular full skin examinations (FSEs) with a specialist clinician are recommended by most guidelines and are critical for early skin cancer detection. However, screening engagement remains variable. This narrative review synthesises the existing literature examining participation in FSEs amongst SOTRs. Seventeen studies were identified and grouped into patient-, clinician- and system-level domains. Across studies, adherence varied between countries and healthcare settings. Patient-level barriers to screening predominantly related to sociodemographic factors. Clinician-level factors that influenced screening practice included guideline awareness and prioritisation of skin cancer risk. At the system level, structured protocols and access to dermatologists improved screening uptake. Identifying and addressing barriers across these domains may improve screening uptake in this at-risk population.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"325-337"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.70134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147810118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring and Comparing the Psychosocial Impacts of Vitiligo on a Broader Scale: An International Survey via the Use of Social Media 在更大范围内探索和比较白癜风的社会心理影响:一项通过使用社交媒体进行的国际调查。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-06-15 DOI: 10.1111/ajd.70157
Megan Noda, Mathew Ghodsian, Jonathan Chan
{"title":"Exploring and Comparing the Psychosocial Impacts of Vitiligo on a Broader Scale: An International Survey via the Use of Social Media","authors":"Megan Noda,&nbsp;Mathew Ghodsian,&nbsp;Jonathan Chan","doi":"10.1111/ajd.70157","DOIUrl":"10.1111/ajd.70157","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background/Objectives</h3>\u0000 \u0000 <p>Vitiligo is associated with substantial psychosocial burden; however, community-based patient-reported data remain limited, and existing instruments may not fully reflect patients' lived experience. This study explored the psychosocial impacts of vitiligo using social media-based recruitment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Adults (≥ 18 years) with physician-confirmed or self-reported vitiligo were recruited via Facebook support groups between December 2023 and February 2024 to complete an anonymous online survey. Quantitative data included demographics and the 15-item VitiQoL questionnaire. Qualitative responses addressing challenges, management, and barriers to care were analysed inductively, with emergent themes integrated with quantitative findings. Descriptive statistics and exploratory independent-samples t-tests were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 181 participants responded, predominantly female (81.8%), and mainly from the UK (53.59%) and Australia (29.83%). Qualitative analysis identified stigmatisation and sun exposure as prominent challenges. Head and neck involvement was associated with poorer QoL, including altered grooming behaviours (3.78, SD 2.12, <i>p</i> &lt; 0.001), clothing adaptations (4.42, SD 1.96, <i>p</i> &lt; 0.001), difficulties forming new friendships (2.21, SD 2.01, <i>p</i> &lt; 0.001), and limitations in daily activities (2.93, SD 2.15, <i>p</i> &lt; 0.001). Males reported greater emotional impact (M = 4.27, SD 1.91, <i>p</i> = 0.014) and more difficulty forming friendships (M = 2.85, SD 2.09, <i>p</i> = 0.004) than female participants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Vitiligo is associated with significant psychosocial challenges, particularly stigma-related distress, behavioural adaptations, and participation restrictions. These findings highlight the importance of addressing psychosocial wellbeing in clinical care, and the need for comprehensive QoL measures that better capture psychosocial and participation-related impacts.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"338-347"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.70157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148257076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytokine and Inflammasome Gene Polymorphisms in Vitiligo: A Candidate-Polymorphism Meta-Analysis 白癜风的细胞因子和炎性体基因多态性:候选多态性荟萃分析。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-06-08 DOI: 10.1111/ajd.70154
Imran Hossain, Md. Saifuddin Molla
{"title":"Cytokine and Inflammasome Gene Polymorphisms in Vitiligo: A Candidate-Polymorphism Meta-Analysis","authors":"Imran Hossain,&nbsp;Md. Saifuddin Molla","doi":"10.1111/ajd.70154","DOIUrl":"10.1111/ajd.70154","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e369-e372"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148203911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Skin Checks for Skin Cancer Screening—An Audit of the Triage Performance of DermScreen 用于皮肤癌筛查的数字皮肤检查——对DermScreen分诊性能的审计。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-06-02 DOI: 10.1111/ajd.70149
Kathryn Chen, Nicholas H. S. Wong, Oliver Sun, Rhiannon Grange, Nerilee Wall, Lisa Byrom, Ron Shnier, Stephen P. Shumack, Philip L. Tong
{"title":"Digital Skin Checks for Skin Cancer Screening—An Audit of the Triage Performance of DermScreen","authors":"Kathryn Chen,&nbsp;Nicholas H. S. Wong,&nbsp;Oliver Sun,&nbsp;Rhiannon Grange,&nbsp;Nerilee Wall,&nbsp;Lisa Byrom,&nbsp;Ron Shnier,&nbsp;Stephen P. Shumack,&nbsp;Philip L. Tong","doi":"10.1111/ajd.70149","DOIUrl":"10.1111/ajd.70149","url":null,"abstract":"<div>\u0000 \u0000 <p>In Australia, population-level early skin cancer detection is limited because dermatology service capacity is insufficient to meet demand. Digital skin check models, which combine total body photography by nurse melanographers with remote dermatologist review of clinical and dermoscopic images, may improve triage of suspicious lesions and prioritise access to in-person assessment. In this retrospective audit of 1577 reports, we evaluated the performance of one such service, DermScreen, as a triage tool to expedite in-person dermatologist review for suspicious lesions and to support more efficient use of limited dermatology resources by reducing unnecessary consultations and enabling more targeted biopsy decisions.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"348-352"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148142642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Primary Cutaneous BRAFV600E+ Langerhans Cell Histiocytosis, With Underlying Chronic Myelomonocytic Leukaemia, Responsive to Dabrafenib With Subsequent Undetectable Circulating Cell Free DNA 原发性皮肤BRAFV600E+朗格汉斯细胞组织细胞增多症伴潜在慢性髓单细胞性白血病,对达非尼有反应,随后循环细胞游离DNA检测不到
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-05-26 DOI: 10.1111/ajd.70143
Kate Simpson, Friyana Bhabha, Alicia Snowden, Stephen Lade, Piers Blombery, Chris McCormack, Henry Miles Prince
{"title":"A Case of Primary Cutaneous BRAFV600E+ Langerhans Cell Histiocytosis, With Underlying Chronic Myelomonocytic Leukaemia, Responsive to Dabrafenib With Subsequent Undetectable Circulating Cell Free DNA","authors":"Kate Simpson,&nbsp;Friyana Bhabha,&nbsp;Alicia Snowden,&nbsp;Stephen Lade,&nbsp;Piers Blombery,&nbsp;Chris McCormack,&nbsp;Henry Miles Prince","doi":"10.1111/ajd.70143","DOIUrl":"10.1111/ajd.70143","url":null,"abstract":"<div>\u0000 \u0000 <p>We present a case of <i>BRAF</i><sup>V600E+</sup> primary cutaneous Langerhan cell histiocytosis (LCH), with corresponding circulating cell free DNA (cfDNA), which responded to treatment with dabrafenib, and simultaneously saw corresponding <i>BRAF</i><sup>V600E</sup> cfDNA become undetectable. A concomitant diagnosis of chronic myelomonocytic leukaemia (CMML) was suspected with identification of <i>TP53</i>, <i>TET2</i>, <i>RAS</i> and <i>CBL</i> variants identified through molecular testing on the initial skin biopsy, and CMML later confirmed on bone marrow biopsy. Whilst the link between LCH and several haematological malignancies is documented, the mechanism is still unclear. In this case, the LCH most likely developed from an already abnormal myeloid compartment and highlights the need for clinical vigilance and appropriate investigation, where effective treatments for these conditions exist.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"360-363"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichophyton mentagrophytes Genotype VII: Sexually Transmitted Infection Beyond MSM 毛癣菌基因型VII:男男性接触者以外的性传播感染。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-05-22 DOI: 10.1111/ajd.70144
Gabriele Perego, Anna Grancini, Susanna Benardon, Stefano Ramoni, Angelo V. Marzano, Paolo Bortoluzzi
{"title":"Trichophyton mentagrophytes Genotype VII: Sexually Transmitted Infection Beyond MSM","authors":"Gabriele Perego,&nbsp;Anna Grancini,&nbsp;Susanna Benardon,&nbsp;Stefano Ramoni,&nbsp;Angelo V. Marzano,&nbsp;Paolo Bortoluzzi","doi":"10.1111/ajd.70144","DOIUrl":"10.1111/ajd.70144","url":null,"abstract":"&lt;p&gt;&lt;i&gt;Trichophyton mentagrophytes&lt;/i&gt; is a zoophilic dermatophyte causing superficial fungal infection. Among its variants, &lt;i&gt;Trichophyton mentagrophytes&lt;/i&gt; genotype VII (TMVII) has been recently recognised as a distinct genotype and has been increasingly linked to sexually transmitted infections [&lt;span&gt;1&lt;/span&gt;]. While the earliest reports of TMVII infections in Europe mainly involved patients who had had contact with commercial sex workers in Southeast Asia [&lt;span&gt;2&lt;/span&gt;], more recent evidence indicates that TMVII is circulating across the continent, particularly among men who have sex with men (MSM) [&lt;span&gt;3-6&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;In a previous study, we documented the first confirmed cases of sexually transmitted TMVII infection in Italy, all occurring in MSM patients and manifesting as tinea barbae. Here, we report a more recent case series collected at our Dermatology Unit between October 2024 and December 2025, which shows a more heterogeneous patient population. Epidemiological and clinical data are summarised in Table 1. The diagnosis of &lt;i&gt;T. mentagrophytes&lt;/i&gt; infection was established through mycological cultures, and genotyping of the ITS1–2 region confirmed the presence of TMVII. Patients were treated with oral terbinafine 250 mg daily or itraconazole 200 mg daily for 4 weeks in combination with topical antifungal therapy. Treatment was effective in all patients, with no evidence of recurrence or antifungal resistance.&lt;/p&gt;&lt;p&gt;Following the first reports of autochthonous sexually transmitted TMVII infections in France [&lt;span&gt;3, 4&lt;/span&gt;] and Italy [&lt;span&gt;5&lt;/span&gt;], increasing evidence has documented the spread of this infection across several European countries and worldwide [&lt;span&gt;2&lt;/span&gt;]. While early reports described cohorts composed exclusively of men who have sex with men (MSM) [&lt;span&gt;3-6&lt;/span&gt;], subsequent studies have identified TMVII infections in heterosexual individuals of both sexes [&lt;span&gt;1, 7, 8&lt;/span&gt;]. In our cohort, more than 60% of patients (8/13) reported heterosexual orientation and about 23% (3/13) were women.&lt;/p&gt;&lt;p&gt;TMVII is not restricted to a specific sexual related anatomical site (e.g., beard or pubo-genital area) but may involve multiple body regions, such as arms and legs [&lt;span&gt;1&lt;/span&gt;]. Many of our patients showed atypical presentations of tinea corporis, including painful erythematous plaques, pustules and nodules, occasionally progressing to granulomatous lesions or erosive lesions with eschar formation [&lt;span&gt;2&lt;/span&gt;]. Although TMVII is transmitted through anthropophilic contact, its close genetic relationship with zoophilic genotypes within the &lt;i&gt;T. mentagrophytes&lt;/i&gt; complex may account for the marked inflammatory response observed [&lt;span&gt;7&lt;/span&gt;]. Interestingly, more inflammatory lesions predominantly involved hair-bearing areas, such as the beard and pubic region, whereas lesions on the trunk or shaved perigenital skin more often displayed the classical ringworm morphology. Two patients in our c","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e365-e368"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.70144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148004298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cercarial Dermatitis (aka ‘Swimmers’ or ‘Duck Itch’) in New Zealand Lakes 新西兰湖区的子宫颈皮炎(又名“游泳者”或“鸭子痒”)。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-05-02 DOI: 10.1111/ajd.70131
Marius Rademaker, Eugene Tan
{"title":"Cercarial Dermatitis (aka ‘Swimmers’ or ‘Duck Itch’) in New Zealand Lakes","authors":"Marius Rademaker,&nbsp;Eugene Tan","doi":"10.1111/ajd.70131","DOIUrl":"10.1111/ajd.70131","url":null,"abstract":"<div>\u0000 \u0000 <p>Despite ‘Swimmers Itch’ having been first reported in the Transactions of the Royal Society of South Australia in 1941, and shortly afterwards in the New Zealand Medical Journal in 1944, there remain few publications in the Australasian dermatology journals.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e358-e361"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147810199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyoderma Gangrenosum: Association of Ulcer Size With Clinical Characteristics and Healing Outcomes 坏疽性脓皮病:溃疡大小与临床特征和愈合结果的关系。
IF 1.6 4区 医学
Australasian Journal of Dermatology Pub Date : 2026-09-12 Epub Date: 2026-06-23 DOI: 10.1111/ajd.70168
Jacqueline Jiang, Edmund Wee, Dale Jobson, Robert Kelly
{"title":"Pyoderma Gangrenosum: Association of Ulcer Size With Clinical Characteristics and Healing Outcomes","authors":"Jacqueline Jiang,&nbsp;Edmund Wee,&nbsp;Dale Jobson,&nbsp;Robert Kelly","doi":"10.1111/ajd.70168","DOIUrl":"10.1111/ajd.70168","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Pyoderma gangrenosum (PG) is an ulcerative inflammatory dermatosis that is poorly characterised from a diagnostic and therapeutic perspective. We evaluated the clinical characteristics and healing outcomes in patients with PG according to ulcer size.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We reviewed the medical records of patients with PG presenting to a tertiary hospital in Melbourne, Australia, from 20 December 2011 to 11 June 2024. We collected data on demographics, clinical characteristics, and classified cases into small (&lt; 64 cm<sup>2</sup>) or large ulcers (≥ 64 cm<sup>2</sup> or any tendon or muscle on view) according to the size of the largest ulcer during the treatment course. Healing outcomes assessed included rates of initial healing, healing time, recurrence rate, healing after recurrence, level of systemic treatment required, and mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>81 cases of PG were identified, including 38 (46.9%) small and 43 (53.1%) large ulcers. Large ulcers were associated with a history of multiple ulcers, peripheral vascular disease, and higher rates of advanced treatment (biologic or intravenous immunoglobulin therapy). After adjusting for age, sex, and peripheral vascular disease, large ulcers remained independently associated with lower rates of initial healing, higher rates of recurrence, lower rates of healing after recurrence, and longer healing times (all <i>p</i> &lt; 0.05). Ulcer size was not associated with age, sex, ulcer location, tissue pathergy, inflammatory bowel disease, haematological malignancy, inflammatory arthritis, or diabetes mellitus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>PG is a highly morbid condition that is slow to heal and frequently recurs. Ulcer size is an important predictor of healing outcomes. It is thus a meaningful way of stratifying patients and may provide useful prognostic information regarding the expected disease course.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e353-e357"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148300642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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