Mattias A S Henning, Jessica N Juntermanns, Nikolai Loft, Daniel Isufi, Claus Zachariae
{"title":"Childhood-Onset and Adolescent-Onset Primary Hyperhidrosis in Children: A Cross-Sectional Study.","authors":"Mattias A S Henning, Jessica N Juntermanns, Nikolai Loft, Daniel Isufi, Claus Zachariae","doi":"10.1111/ajd.70212","DOIUrl":"https://doi.org/10.1111/ajd.70212","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perineal Nodular Induration (Cyclist's Nodule).","authors":"Marius Rademaker","doi":"10.1111/ajd.70210","DOIUrl":"https://doi.org/10.1111/ajd.70210","url":null,"abstract":"<p><p>Perineal nodular induration, also called Cyclist's nodule, is an uncommon, benign pseudotumour of the perineal soft tissues that arises almost exclusively in individuals who engage in prolonged saddle-based sports, most notably road cycling. It is thought to result from chronic mechanical microtrauma-pressure, vibration, and shear-transmitted between the ischial tuberosities and a hard saddle. Management includes prolonged rest from cycling, bike-fit and behavioural modification, intralesional corticosteroid injection, or surgical excision for refractory disease.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of Anti-IgE Antibodies Against Basement Membrane Zone in Bullous Pemphigoid by Direct Immunofluorescence: Prevalence, Associations and Significance.","authors":"Saurodeep Basu, Raghavendra Rao","doi":"10.1111/ajd.70211","DOIUrl":"https://doi.org/10.1111/ajd.70211","url":null,"abstract":"<p><strong>Background: </strong>Considerable uncertainty exists regarding the prevalence and clinical significance of basement membrane zone (BMZ) anti-IgE antibodies in bullous pemphigoid (BP).</p><p><strong>Objective: </strong>To assess the frequency of linear BMZ anti-IgE antibody deposition by direct immunofluorescence (DIF) and evaluate its association with disease severity and potential diagnostic utility in BP.</p><p><strong>Methods: </strong>This prospective cross-sectional analytical study enrolled 50 patients with newly diagnosed BP, confirmed by DIF and serology, and 50 non-BP controls. Associations with clinical disease severity and laboratory parameters were analysed. An exploratory diagnostic performance analysis of anti-IgE positivity was also performed.</p><p><strong>Results: </strong>The mean age of the study and control populations was 65.1 ± 17 and 58.2 ± 18.5 years, respectively. BMZ anti-IgE antibodies were detected in 27/50 BP patients (54%) and 1/50 (2%) controls [odds ratio (OR) 57.5, 95% confidence interval (CI), 7.4-449.7; p < 0.001]. Anti-IgE positivity was significantly associated with bullous pemphigoid disease area index (BPDAI) total and BPDAI-Erosion-Blister scores, total body surface area, high absolute eosinophil count (AEC), and increased serum IgE. In multivariate logistic regression, elevated AEC and increased serum IgE independently predicted anti-IgE positivity [adjusted-OR (95% CI): 1.004 (1.000-1.008); p = 0.037 and 1.003 (1.000-1.005); p = 0.033, respectively]. Anti-IgE positivity demonstrated 54% sensitivity, 98% specificity and a positive likelihood ratio of 27.</p><p><strong>Conclusions: </strong>BMZ anti-IgE antibody was present in over half of the patients with BP and was associated with greater disease severity, eosinophilia and elevated serum IgE. Given its high specificity but modest sensitivity, anti-IgE positivity may serve as a useful adjunctive marker to support, rather than exclude, the diagnosis of BP.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Lentigo Maligna Presenting as Repigmentation of Hair in a Scalp That Previously Underwent Radiotherapy for Tinea Capitis","authors":"Madeleine Louise Kelly, Ken Low, Robert M. Miller","doi":"10.1111/ajd.70146","DOIUrl":"10.1111/ajd.70146","url":null,"abstract":"<p>Lentigo maligna has occasionally been noted to have the capacity to invade and repigment grey hairs. We present a case of a 78-year-old male who presented with a patch of brown hair on the vertex of the scalp in an area of previously white hair. The patient had previous radiotherapy to the site as a child for the treatment of tinea capitis. Initial histology revealed a lentigo maligna in situ subtype and the patient underwent surgical excision with split thickness skin graft. An invasive component was identified on histological examination of the entire lesion. This case highlights not only the rare entity of hair repigmentation as a sign of malignancy but also highlights past scalp radiotherapy as a possible risk factor in the development of melanoma.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e362-e364"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.70146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148142563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manisha Kumar, Jonathan Nakad, Cindy Kok, John Frew, Tara Sholji
{"title":"Interventions to Improve Treatment Adherence in Psoriasis: A Systematic Review","authors":"Manisha Kumar, Jonathan Nakad, Cindy Kok, John Frew, Tara Sholji","doi":"10.1111/ajd.70145","DOIUrl":"10.1111/ajd.70145","url":null,"abstract":"<div>\u0000 \u0000 <p>Psoriasis is a chronic inflammatory skin disease for which long-term treatment adherence is essential to achieve and maintain disease control. However, adherence remains suboptimal in routine clinical practice. While a range of interventions have been developed to support adherence, variability in intervention design and outcome reporting has limited the ability to draw clear conclusions regarding their effectiveness. This systematic review aimed to evaluate interventions designed to improve treatment adherence among patients with psoriasis, to synthesise evidence on adherence outcomes as well as associated clinical and patient-reported effects. A systematic literature search was conducted across major electronic databases in accordance with PRISMA guidelines to identify studies assessing adherence-enhancing interventions in psoriasis. Twenty-six studies were included. Digital and technology-supported interventions, including mobile applications, short message service reminders and electronic monitoring-supported platforms were the most frequently evaluated and were generally associated with modest improvements in adherence when compared to usual care. Healthcare professional-led interventions such as nurse and pharmacist delivered models demonstrated potential benefits in adherence. Across studies, improvements in adherence were more consistently observed than improvements in clinical severity and quality-of-life outcomes. Substantial heterogeneity in intervention design, adherence measurement and follow-up duration precluded quantitative synthesis. This systematic review highlights the diversity of approaches used to address treatment adherence benefits. However, inconsistent effects on clinical outcomes and methodological heterogeneity underpin the need for standardised adherence measures, longer term follow-up and further evaluation of scalable, multidisciplinary adherence support strategies.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"e337-e347"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148052270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zachary Warren, Friyana Bhabha, Belinda A Campbell, Carrie van der Weyden, H Miles Prince, Odette Buelens, Michelle K Yong, Christopher McCormack
{"title":"The Development of Non-Tuberculosis Mycobacterial Infections in Sézary Syndrome: A Case Report of Two Patients.","authors":"Zachary Warren, Friyana Bhabha, Belinda A Campbell, Carrie van der Weyden, H Miles Prince, Odette Buelens, Michelle K Yong, Christopher McCormack","doi":"10.1111/ajd.70206","DOIUrl":"https://doi.org/10.1111/ajd.70206","url":null,"abstract":"<p><p>Sézary syndrome (SS) is a rare cutaneous T-cell lymphoma associated with increased risks of opportunistic and atypical infections. This report presents two patients with SS and concurrent non-tuberculosis mycobacterial cutaneous infections. Although rare, difficult to diagnose and challenging to treat, these cases highlight the importance of considering atypical infectious causes in patients with SS.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle K. Y. Chen, Madeline Wang, Kevin Phan, Robert Rawson, Margit Polcz, Charlotte Thomas
{"title":"Neutrophilic Eccrine Hidradenitis in a Patient With Intranasal Cocaine Use","authors":"Michelle K. Y. Chen, Madeline Wang, Kevin Phan, Robert Rawson, Margit Polcz, Charlotte Thomas","doi":"10.1111/ajd.70093","DOIUrl":"10.1111/ajd.70093","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"374-376"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Duc V. Le, Tung S. Tran, Hue T. T. Tran, David A. Wetter, Giang H. Nguyen
{"title":"Drug and Vaccine-Associated Erythema Nodosum: Insights From the FAERS and VAERS Database","authors":"Duc V. Le, Tung S. Tran, Hue T. T. Tran, David A. Wetter, Giang H. Nguyen","doi":"10.1111/ajd.70140","DOIUrl":"10.1111/ajd.70140","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"370-373"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147926056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paediatric Psoriasis and the Topical Treatment Guidance Gap in Australia","authors":"James Gaston, Benjamin S. Daniel","doi":"10.1111/ajd.70148","DOIUrl":"10.1111/ajd.70148","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"67 6","pages":"382-383"},"PeriodicalIF":1.6,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148136224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}