The Use of Etanercept in the Palliative Treatment of a Patient With Generalised Bullous Fixed Drug Eruption.

IF 1.8 4区医学 Q2 DERMATOLOGY

Australasian Journal of Dermatology Pub Date : 2025-09-02 DOI:10.1111/ajd.14577

Olga Pawlik, Timothy Cowan, Andrew Miller

引用次数: 0

Abstract

Generalised Bullous Fixed Drug Eruption (GBFDE) is a subtype of Fixed Drug Eruption (FDE) characterised by the development of generalised blisters on the background of dusky macules. There is no gold standard treatment, but the condition is conventionally managed with supportive care, topical and oral steroids and occasionally ciclosporin. We describe the case of a 75-year-old female with GBFDE, who demonstrated a rapid halt in disease progression and re-epithelialisation following a single dose of etanercept. This case highlights the potential role of etanercept in the management of GBFDE.

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依那西普在广泛性大疱性固定药疹的姑息治疗中的应用。

广泛性大疱性固定药疹（GBFDE）是固定药疹（FDE）的一个亚型，其特征是在暗斑的背景下发展为广泛性水泡。没有黄金标准的治疗方法，但这种情况通常是通过支持性护理、局部和口服类固醇以及偶尔使用环孢素来治疗的。我们描述了一个75岁的女性GBFDE病例，她在单剂量依那西普后表现出疾病进展和再上皮化的快速停止。这个病例强调了依那西普在GBFDE治疗中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Australasian Journal of Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

5.00%

发文量

186

审稿时长

6-12 weeks

期刊介绍： Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.