Asian Biomedicine最新文献_第7页

Plant-based diets in patients with chronic kidney disease. 慢性肾病患者的植物性饮食。

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2024-03-20 eCollection Date: 2024-02-01 DOI: 10.2478/abm-2024-0002

Wannasit Wathanavasin, Piyawan Kittiskulnam, Kirsten L Johansen

引用次数: 0

Early detection and management of hearing loss to improve the quality of life. 及早发现和管理听力损失，提高生活质量。

IF 0.4 4区医学

Asian Biomedicine Pub Date : 2024-03-20 eCollection Date: 2024-02-01 DOI: 10.2478/abm-2024-0001

引用次数: 0

Reliability of lateral wall-thickness measurement in trochanteric fractures and parameters associated with lateral wall integrity. 转子骨折侧壁厚度测量的可靠性以及与侧壁完整性相关的参数。

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2024-03-20 eCollection Date: 2024-02-01 DOI: 10.2478/abm-2024-0005

Chindarat Ratanakornphan, Thanachart Pikulhom, Somjet Jenvorapoj, Chavarin Amarase, Saran Tantavisut

{"title":"Reliability of lateral wall-thickness measurement in trochanteric fractures and parameters associated with lateral wall integrity.","authors":"Chindarat Ratanakornphan, Thanachart Pikulhom, Somjet Jenvorapoj, Chavarin Amarase, Saran Tantavisut","doi":"10.2478/abm-2024-0005","DOIUrl":"10.2478/abm-2024-0005","url":null,"abstract":"Background: The AO Foundation/Orthopaedic Trauma Association (AO/OTA) introduced a new trochanteric fracture classification in January 2018, concerning the lateral wall integrity. It suggested the intramedullary nail fixation in patients with an incompetent lateral wall fracture.Objective: To determine the reliability of lateral wall-thickness measurement and the fracture parameters associated with lateral wall integrity.Methods: This retrospective study evaluated patients with an intertrochanteric fracture who had had surgery in King Chulalongkorn Memorial Hospital between January 2014 and January 2019. The lateral wall was measured by anteroposterior plain radiography by four raters, two times each. The demographic data and fracture parameters were assessed and compared with respect to lateral wall integrity.Result: In a total of 236 femurs and 232 patients having the 2018 AO/OTA-specified 31A1 and 31A2 intertrochanteric fractures, the lateral wall-thickness measurement showed excellent inter-rater reliability at 0.944 (0.927-0.957) and good-to-excellent intra-rater reliability ranging from 0.835 to 0.972. The parameters associated with lateral wall incompetence as per the multivariate logistic regression analysis were fracture angle (odds ratio [OR] = 0.95), distal greater trochanter involvement (OR = 9.47), and fragments at the intertrochanter area (OR = 4.49) and at the lesser trochanter (OR = 2.6).Conclusion: Some of the parameters related to trochanteric fractures are associated with lateral wall incompetence. Lateral wall-thickness measurement is a reproducible method, which has been suggested for use by the AO/OTA 2018 classification. It is easy to use and can help select the appropriate treatment for intertrochanteric fracture patients.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"18 1","pages":"24-29"},"PeriodicalIF":0.6,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10954081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140183642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases 侧流检测：一种用于感染和非传染性疾病的前景广阔的快速护理点检测工具

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-12-28 DOI: 10.2478/abm-2023-0068

Kumaravel Vealan, Narcisse Joseph, Sharizah Alimat, Anandi S. Karumbati, Karuppiah Thilakavathy

{"title":"Lateral flow assay: a promising rapid point-of-care testing tool for infections and non-communicable diseases","authors":"Kumaravel Vealan, Narcisse Joseph, Sharizah Alimat, Anandi S. Karumbati, Karuppiah Thilakavathy","doi":"10.2478/abm-2023-0068","DOIUrl":"https://doi.org/10.2478/abm-2023-0068","url":null,"abstract":"The point-of-care testing (POCT) approach has established itself as having remarkable importance in diagnosing various infectious and non-communicable diseases (NCDs). The POCT approach has succeeded in meeting the current demand for having diagnostic strategies that can provide fast, sensitive, and highly accurate test results without involving complicated procedures. This has been accomplished by introducing rapid bioanalytical tools or biosensors such as lateral flow assays (LFAs). The production cost of these tools is very low, allowing developing countries with limited resources to utilize them or produce them on their own. Thus, their use has grown in various fields in recent years. More importantly, LFAs have created the possibility for a new era of incorporating nanotechnology in disease diagnosis and have already attained significant commercial success worldwide, making POCT an essential approach not just for now but also for the future. In this review, we have provided an overview of POCT and its evolution into the most promising rapid diagnostic approach. We also elaborate on LFAs with a special focus on nucleic acid LFAs.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"21 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139068136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistence of dengue genome in a remotely infected patient 远程感染患者的登革热基因组持续存在

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-12-28 DOI: 10.2478/abm-2023-0072

Soraya Thaivanich, Jirayu Visuthranukul, Kesinee Arunyingmongkol, Udomsak Bunworasate, Padet Siriyasatien, Wanla Kulwichit

引用次数: 0

Antibody response to enterotoxigenic Bacteroides fragilis of Filipino colorectal cancer patients 菲律宾结直肠癌患者对肠毒性脆弱拟杆菌的抗体反应

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-12-28 DOI: 10.2478/abm-2023-0070

Ana Maria D. Cariño, Gregg Austine Balanag, Edrienne Myenna Magat, Allan Fellizar, Teresa Sy Ortin, Oliver Villaflores, Leonardo Guevarra, Pia Marie Albano

{"title":"Antibody response to enterotoxigenic Bacteroides fragilis of Filipino colorectal cancer patients","authors":"Ana Maria D. Cariño, Gregg Austine Balanag, Edrienne Myenna Magat, Allan Fellizar, Teresa Sy Ortin, Oliver Villaflores, Leonardo Guevarra, Pia Marie Albano","doi":"10.2478/abm-2023-0070","DOIUrl":"https://doi.org/10.2478/abm-2023-0070","url":null,"abstract":"Background Several species of the gut microbiota have been implicated in colorectal cancer (CRC) development. The anaerobic bacterium enterotoxigenic Bacteroides fragilis (ETBF), has been identified to produce fragilysin, a toxin known to cleave E-cadherin, thereby leading to carcinogenesis. Objective To determine the antibody response of CRC patients against ETBF to ascertain whether significant difference exists or whether antibody response is related to tumor grade and tumor stage. Methods Informed consent was obtained from histologically confirmed CRC casesand their age- and sex-matched clinically healthy controls. Plasma samples from the participants were subjected to in-house enzyme-linked immunosorbent assay (ELISA) to determine their antibody levels. Results Using ETBF total protein as coating antigen, 38/39 (97%) CRC cases and 36/39 (92%) controls showed anti-ETBF IgG above cut-off, while all (100%) CRC cases and 36/39 (92%) controls had anti-ETBF IgA levels above cut-off. With culture broth as coating antigen, all (100%) CRC cases and 37/39 (95%) controls had anti-ETBF IgG levels above cut-off. For anti-ETBF IgA, all (100%) cases and controls had levels above cut-off. Statistical analysis reveals no significant difference (P > 0.05) on the number of CRC cases and controls with IgG and IgA antibody levels above cut-off value. Also, there's no significant difference (P > 0.05) in the mean anti-ETBF antibody levels of cases who were at different tumor grade (well differentiated and moderately and poorly differentiated) and tumor stage (early and advanced). Conclusions These results suggest that Filipino CRC cases and their clinically healthy matched controls exhibit antibody responses against ETBF.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"17 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139067460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The value of platelet/lymphocyte ratio in young patient with acute ischemic stroke. 急性缺血性脑卒中年轻患者血小板/淋巴细胞比值的价值。

IF 0.4 4区医学

Asian Biomedicine Pub Date : 2023-12-28 eCollection Date: 2023-12-01 DOI: 10.2478/abm-2023-0067

引用次数: 0

The dose of the normal saline pre-infusion and other risk factors for amphotericin B deoxycholate-associated acute kidney injury 输注前生理盐水的剂量和两性霉素 B 去氧胆酸盐相关急性肾损伤的其他风险因素

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-12-28 DOI: 10.2478/abm-2023-0071

Mathurot Virojanawat, Somkanya Tungsanga, Leilani Paitoonpong, Pisut Katavetin

{"title":"The dose of the normal saline pre-infusion and other risk factors for amphotericin B deoxycholate-associated acute kidney injury","authors":"Mathurot Virojanawat, Somkanya Tungsanga, Leilani Paitoonpong, Pisut Katavetin","doi":"10.2478/abm-2023-0071","DOIUrl":"https://doi.org/10.2478/abm-2023-0071","url":null,"abstract":"Background Conventional amphotericin B deoxycholate (AmBd) is the preferred amphotericin B formulation in countries with limited resources despite its nephrotoxicity. Normal saline pre-infusion is a recommended measure to reduce the risk of nephrotoxicity in patients receiving AmBd. Objectives To examine the effect of different normal saline solution (NSS) pre-infusion doses, and other potential risk factors, on the development of acute kidney injury (AKI) in patients with invasive fungal infection receiving AmBd. Methods Adult patients with invasive fungal infections who received intravenous AmBd were included in this retrospective study. Doses of the normal saline pre-infusion were adjusted to the body weight (NSS/BW) and the daily dose of amphotericin B (NSS/AmBd). Kaplan–Meier survival analysis was used to estimate 14 d AKI-free survival rates, and the log-rank test was used to compare AKI-free survivals between groups. Results The present study included 60 patients; 31 patients developed AKI during the AmBd therapy. The overall 14 d AKI-free survival was 48.3%. NSS/AmBd, but not NSS/BW, was associated with AKI-free survival in patients receiving AmBd: the higher the NSS/AmBd, the higher the AKI-free survival. Gender, baseline blood urea nitrogen (BUN), and baseline plasma bicarbonate (Bicarb) also affected AKI-free survival. Female gender, higher BUN, and lower Bicarb were associated with higher AKI-free survival. Conclusions The present study suggests that low NSS/AmBd, male gender, low BUN, and high Bicarb are risk factors for AmBd-associated AKI. Excluding gender, these risk factors are potentially modifiable and would guide tailoring appropriate preventive measures for AmBd-associated AKI.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"13 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139072192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The early predictive value of platelet-to-lymphocyte ratio to hemorrhagic transformation of young acute ischemic stroke 血小板淋巴细胞比值对年轻急性缺血性卒中出血转化的早期预测价值

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-12-28 DOI: 10.2478/abm-2023-0069

Huijun Wen, Ning Wang, Min Lv, Yue Yang, Hongmei Liu

{"title":"The early predictive value of platelet-to-lymphocyte ratio to hemorrhagic transformation of young acute ischemic stroke","authors":"Huijun Wen, Ning Wang, Min Lv, Yue Yang, Hongmei Liu","doi":"10.2478/abm-2023-0069","DOIUrl":"https://doi.org/10.2478/abm-2023-0069","url":null,"abstract":"Background The increasing incidence of acute ischemic stroke (AIS) necessitates a comprehensive understanding of the related factors. Hemorrhagic transformation (HT), a severe complication of AIS, is influenced by platelet-induced inflammation and lymphocyte levels. Objective To measure the predictive value of platelet-to-lymphocyte ratio (PLR) in the occurrence of HT in young AIS patients. Methods Data of young AIS patients (n = 157) admitted to the hospital for the first time were retrospectively collected. The patients were divided into HT (63 patients) and non-HT groups (94 patients) on the basis of whether HT had occurred after admission. The National Institute of Health stroke scale (NIHSS) score was used to determine the severity of clinical symptoms. The relationship between PLR and HT and NIHSS scores was analyzed to evaluate the predictive value of PLR in the occurrence of HT using receiver operating characteristic (ROC) and area under the curve (AUC). Results Multivariate analysis showed that PLR and NIHSS are independent risk factors of HT. The PLR value of the observation group was positively associated with the NIHSS score (r = 0.8075, P < 0.0001). According to the PLR prediction about the occurrence of HT, an AUC of 0.713 (95% CI, 0.652–0.781), a cut-off value of 109.073, and a sensitivity and specificity of 0.806 and 0.674, respectively, were obtained. Conclusions PLR value can predict the possibility of HT in young AIS patients to a certain extent. To take effective measures to prevent HT in advance has crucial clinical significance according to PLR value.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"97 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139068180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital pulmonary hypoplasia combined with congenital cardiac disease and ectopic kidney: a case report. 先天性肺发育不全合并先天性心脏病和异位肾：一例报告。

IF 0.6 4区医学

Asian Biomedicine Pub Date : 2023-10-26 eCollection Date: 2023-10-01 DOI: 10.2478/abm-2023-0066

Ling Lu, Sujuan Hu, Gaoyan Wang, Rong Jin, Renzheng Guan, Fengjing Cui, Zhenghai Qu, Dongyun Liu

{"title":"Congenital pulmonary hypoplasia combined with congenital cardiac disease and ectopic kidney: a case report.","authors":"Ling Lu, Sujuan Hu, Gaoyan Wang, Rong Jin, Renzheng Guan, Fengjing Cui, Zhenghai Qu, Dongyun Liu","doi":"10.2478/abm-2023-0066","DOIUrl":"https://doi.org/10.2478/abm-2023-0066","url":null,"abstract":"Background: Congenital pulmonary hypoplasia (CPH) is a rare pulmonary disease featured by incomplete development of pulmonary tissues. Its diagnosis is still a challenge as patients are usually misdiagnosed as atelectasis.Case presentation: A female neonate was admitted to our hospital due to post-birth jaundice for 12 hrs. Physical examination showed accelerated breathing. There was no respiratory sound in the left lung. Chest film indicated decline of lucency in the left lung. Chest CT scan indicated absence of left lung and primary bronchus of the left lung. The boundary between left mediastinum was not clearly displayed. Three-dimensional CT scan indicated absence of left lung and left principal bronchus. Cardiac ultrasonography confirmed congenital heart disease. She showed ectopic kidney. Finally, she was diagnosed with CPH concurrent with congenital heart disease and ectopic kidney.Conclusions: On 17-month follow-up visit, the patient is still survived, but she presents with obstruction in ventilation function.","PeriodicalId":8501,"journal":{"name":"Asian Biomedicine","volume":"17 5","pages":"244-248"},"PeriodicalIF":0.6,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0