{"title":"Biomarcadores tomográficos en OCT: de la descripción a la cuantificación automatizada en la práctica clínica","authors":"R. Abreu-González, P. Udaondo, J. Donate-López","doi":"10.1016/j.oftal.2026.502531","DOIUrl":"10.1016/j.oftal.2026.502531","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502531"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Hamdy Ghoraba, M.A. Abdelhafez Elsayed, A.H. Hamdi Ghoraba, M. Leila
{"title":"Cierre inusual de un gran agujero macular traumático después de una vitrectomía pars plana poco convencional","authors":"H. Hamdy Ghoraba, M.A. Abdelhafez Elsayed, A.H. Hamdi Ghoraba, M. Leila","doi":"10.1016/j.oftal.2026.502564","DOIUrl":"10.1016/j.oftal.2026.502564","url":null,"abstract":"<div><div>This retrospective case report describes the closure of a large traumatic macular hole following PPV, posterior hyaloid detachment, and air tamponade despite the inability to perform ILM surgery. An 11-year-old male presented with a full-thickness macular hole following blunt trauma and a BCVA of counting fingers. Serial OCT examination precluded spontaneous closure. The surgery consisted of PPV and induction of posterior hyaloid detachment. All attempts to perform a modified ILM flap technique failed. Air tamponade was used at the end of the surgery. The post-operative OCT images showed U-type closure of the hole. The BCVA improved to 6/60. We recommend a modified ILM flap technique in large full-thickness traumatic macular holes to improve the functional and anatomical outcomes. Despite the inability of ILM surgery, the hole closure described in this report is an unusual finding.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502564"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.A. Gegúndez-Fernández, B. Burgos-Blasco, M. Ariño-Gutiérrez, P. Pérez-García, M. Molero-Senosiain, D. Díaz-Valle
{"title":"Autoqueratoplastia lamelar anterior rotacional manual y asistida por láser de femtosegundo para el tratamiento de opacidades corneales centrales: serie descriptiva de casos","authors":"J.A. Gegúndez-Fernández, B. Burgos-Blasco, M. Ariño-Gutiérrez, P. Pérez-García, M. Molero-Senosiain, D. Díaz-Valle","doi":"10.1016/j.oftal.2026.502612","DOIUrl":"10.1016/j.oftal.2026.502612","url":null,"abstract":"<div><h3>Background and objective</h3><div>To describe the outcomes of rotational anterior lamellar autokeratoplasty (RALK) in central corneal opacities, assessing changes in visual acuity, astigmatism, and central corneal densitometry.</div></div><div><h3>Patients and methods</h3><div>Retrospective descriptive case series of 9 eyes with central opacities and at least 4<!--> <!-->mm of clear peripheral cornea, treated with manual RALK or femtosecond laser-assisted RALK. Demographic and clinical variables, leucoma characteristics, surgical parameters and postoperative evolution of best-corrected distance visual acuity (BCDVA), astigmatism, and central corneal densitometry (CCD) were analyzed. Pre- and postoperative values were compared, with statistical significance set at <em>P</em><.05.</div></div><div><h3>Results</h3><div>Mean age was 44.9 years (5 women, 4 men) with a mean interval to surgery of 19.8 months. Mean leucoma area was 9.73<!--> <!-->mm<sup>2</sup>, with a depth of 268.4<!--> <!-->μm and corneal thickness of 426.3<!--> <!-->μm. Lamellar cut depth was 280.9<!--> <!-->μm and graft diameter 7.9<!--> <!-->mm. Median number of sutures was 4 (range: 3-16). In 5 cases, the opacity was displaced to the superior cornea. BCDVA improved from 0.17 to 0.57 (decimal scale) at one year (<em>P</em>=.008). Astigmatism decreased from 7.7 to 5.9 D (<em>P</em>=.425), and CCD from 61.1 to 25.0% (<em>P</em>=.008). Mean follow-up was 2.4 years. One herpetic recurrence and two additional surgical procedures were recorded.</div></div><div><h3>Conclusions</h3><div>RALK is an effective and safe technique for relocating central corneal opacities outside the visual axis and improving visual function in selected patients. Femtosecond laser assistance provides greater precision and edge congruency, which may facilitate earlier suture removal.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502612"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Puchol-Rizo, J. Suárez-Baraza, A. Muñoz-Gallego
{"title":"Degeneraciones radiales en empalizada e hipoplasia foveal: diagnóstico tardío del síndrome de Stickler en una paciente sin alta miopía","authors":"M. Puchol-Rizo, J. Suárez-Baraza, A. Muñoz-Gallego","doi":"10.1016/j.oftal.2026.502554","DOIUrl":"10.1016/j.oftal.2026.502554","url":null,"abstract":"<div><div>Stickler syndrome is a rare connective tissue disorder with multisystem involvement. We describe the diagnosis and management of Stickler syndrome in a 39-year-old woman with unclassified bone-muscle dysplasia and no prior ocular history, presenting with floaters. Fundus examination showed radial lattice degenerations in both eyes and optical coherence tomography revealed bilateral foveal hypoplasia. Despite not having high myopia (only –4 Diopters in each eye), those fondocopic findings made us investigate further disease. A genetic test was made, and she was found to be heterozygous for the likely pathogenic variant c.1069-2A>T in the COL2A1 gene. Therefore, our patient was finally diagnosed with Stickler syndrome type 1. This case emphasizes the need to consider Stickler syndrome in adults with vitreoretinal degeneration and foveal hypoplasia, even in the absence of high myopia.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502554"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I.A. Domínguez-Varela, M.A. López-Montoy, G.E. Enriquez-Vera
{"title":"Bajo presión: signo de pico de montaña foveal y agujero macular posterior a una rotura de un macroaneurisma arterial retiniano","authors":"I.A. Domínguez-Varela, M.A. López-Montoy, G.E. Enriquez-Vera","doi":"10.1016/j.oftal.2026.502553","DOIUrl":"10.1016/j.oftal.2026.502553","url":null,"abstract":"<div><div>To describe a case of a macular hole (MH) secondary to a submacular hemorrhage caused by a ruptured retinal arterial macroaneursym (RAM). An individual case and its observations were examined. Initial examination revealed no visible MH due to the hemorrhagic clot. Two weeks later, a full-thickness MH measuring 340<!--> <!-->μm was detected. Pneumatic displacement with sulfur hexafluoride (SF6) was performed to reduce hemorrhagic toxicity and potentially promote spontaneous closure. However, after three months, the MH persisted with no evidence of closure, and visual acuity remained reduced (20/150). The Foveal mountain peak sign (FMP) was identified as a useful predictive indicator of MH formation. MHs secondary to ruptured RAMs and submacular hemorrhages may be initially obscured by hemorrhagic clots, complicating early diagnosis. The FMP sign can aid in predicting MH development. Given the risk of persistent MH and visual impairment, especially when the RAM rupture is close to the fovea (<1,500<!--> <!-->μm), early surgical intervention should be considered.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502553"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Astobieta Odriozola, R. Casas Cornejo, J. Cacicedo Fernández de Bobadilla, J. Alonso Fernández, A. Amías Gorostiza, R. Medel Jiménez
{"title":"Carcinoma de glándula lagrimal con diferenciación apocrina: revisión de la bibliografía a propósito de un caso","authors":"A. Astobieta Odriozola, R. Casas Cornejo, J. Cacicedo Fernández de Bobadilla, J. Alonso Fernández, A. Amías Gorostiza, R. Medel Jiménez","doi":"10.1016/j.oftal.2026.502540","DOIUrl":"10.1016/j.oftal.2026.502540","url":null,"abstract":"<div><div>We present the case of a 64-year-old male who had previously undergone surgery for an apocrine carcinoma of the right lacrimal gland, which presented with metastatic spread in the parotid gland and cervical lymph nodes, with subsequent mediastinal and pulmonary lymph node recurrence of a carcinoma with apocrine differentiation expressing androgen receptors in complete response to androgen deprivation therapy.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502540"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Dalma-Weiszhausz, V. Franco-Cárdenas, J.P. Dávila-González
{"title":"Diplopía y papiledema secundario a trombosis del seno longitudinal debido a Factor V Leiden en una paciente joven","authors":"J. Dalma-Weiszhausz, V. Franco-Cárdenas, J.P. Dávila-González","doi":"10.1016/j.oftal.2026.502541","DOIUrl":"10.1016/j.oftal.2026.502541","url":null,"abstract":"<div><div>We describe the ophthalmic findings in a case of cerebral venous thrombosis in a young patient. Observations: A five-year-old female presents with acute onset irritability, somnolence, diplopia, and headache. Ophthalmic exam showed normal vision, large esotropia with a VI nerve palsy and papilledema. MRI demonstrated longitudinal sinus thrombosis associated with Leiden factor V thrombophilia and an asymptomatic pulmonary thrombosis. Anticoagulant therapy was initiated resolving the diplopia and the disc edema, although MRI evidence of the sinus thrombosis persisted. Venous sinus thrombosis should be included in the differential diagnosis of cranial hypertension.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502541"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lentes intraoculares multifocales en el intercambio de lente refractiva: directrices para optimizar su uso e indicaciones","authors":"H.B. Dick, R.D. Gerste, S. Taneri","doi":"10.1016/j.oftal.2026.502615","DOIUrl":"10.1016/j.oftal.2026.502615","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Refractive lens exchange (RLE) with presbyopia-correcting intraocular lenses (IOLs) can provide high levels of spectacle independence, but the procedure is unforgiving. Small residual refractive errors, ocular surface instability, undiagnosed corneal or macular disease, capsule-related IOL malposition, and mismatched expectations are common pathways to postoperative dissatisfaction. The literature on multifocal and extended-range optics is now complemented by consensus documents and functional classification frameworks that help standardize terminology and reduce «marketing-driven» decision making.</div></div><div><h3>Materials and methods</h3><div>This narrative review aims to define practical indications for multifocal IOL use in RLE, clarify borderline cases, summarize the level of evidence supporting current recommendations, and present a staged algorithm for management of dissatisfaction. Priority was given to international consensus statements, systematic reviews/meta-analyses, randomized or comparative studies, large contemporary cohorts, and focused case series dealing with dissatisfaction, neuroadaptation failure, and IOL exchange. The literature was organized around the terms refractive lens exchange, refractive lensectomy, multifocal intraocular lens, trifocal, extended depth of focus, enhanced monofocal, dysphotopsia, neuroadaptation failure, and lens exchange, with emphasis on contemporary evidence available up to January 2026.</div></div><div><h3>Results</h3><div>The evidence can be translated into two clinic-ready workflows. The first is a preoperative selection pathway that starts with patient goals, prioritizes optical quality, treats astigmatism aggressively, and reserves range-first optics for eyes and expectations that can tolerate their trade-offs. The second is a symptom-first rescue pathway built on a strict reversible-first and YAG-last sequence. Borderline eyes are best handled with conservative category selection or deferred surgery. Contemporary exchange series show that persistent neuroadaptation failure may be successfully managed either by exchange to monofocal optics or by exchange to another multifocal platform with a different optical profile, provided that refraction, ocular surface disease, posterior-segment pathology, and IOL position have already been addressed.</div></div><div><h3>Conclusion</h3><div>Multifocal IOLs remain valuable in RLE, but success depends more on indication discipline and rescue sequencing than on lens marketing labels. A structured algorithm, clear counseling, and explicit documentation of rescue options improve safety, readability, and everyday clinical usefulness.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502615"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ruiz del Rio, M.A. Galotto Lopez, E. Gracia Rovira
{"title":"Inhibidores de la Rho-quinasa: equilibrio entre la recuperación de la homeostasis endotelial y epiteliopatía reticulada o en panal","authors":"N. Ruiz del Rio, M.A. Galotto Lopez, E. Gracia Rovira","doi":"10.1016/j.oftal.2026.502576","DOIUrl":"10.1016/j.oftal.2026.502576","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502576"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Benitez-del-Castillo, V. Kosaka-Zanabria, F. González-del-Valle, J.A. Córdoba-Doña, G. Caraballo-Rodríguez, M. Rodriguez-Herrera
{"title":"Análisis de coste-eficiencia del programa Quixote® de teleoftalmología en el Hospital Universitario de Jerez","authors":"J. Benitez-del-Castillo, V. Kosaka-Zanabria, F. González-del-Valle, J.A. Córdoba-Doña, G. Caraballo-Rodríguez, M. Rodriguez-Herrera","doi":"10.1016/j.oftal.2026.502589","DOIUrl":"10.1016/j.oftal.2026.502589","url":null,"abstract":"<div><h3>Background and objective</h3><div>To calculate the cost per patient of ophthalmological care for patients referred from primary care under a telematic model (Quixote® Project, Topcon Healthcare España, Barcelona, Spain.) compared with conventional face-to-face care at the <em>Hospital Universitario de Jerez</em>, within the Jerez, Sierra de Cádiz, and Northwest Coast Health Area (Spain).</div></div><div><h3>Material and methods</h3><div>Comparative analysis of direct costs of telematic ophthalmological care versus the traditional face-to-face model, alongside a retrospective observational evaluation of efficiency after implementation of the Quixote® project. Outcomes included accessibility (mean waiting time in days for ophthalmological care, cumulative primary care waiting list) and patient satisfaction.</div></div><div><h3>Results</h3><div>The direct cost of complete care using the telematic model was €22.47 per patient compared with €32.5 per patient for the face-to-face model. Among 4,288 patients evaluated in the Quixote® project at HUJ, 2,659 patients (62%) required referral for face-to-face hospital assessment, while 1,629 (37.9%) were discharged. The mean waiting time for patients referred from primary care decreased from 89 days to 39 days (−56.8%; 95%CI, 53.8%–58.5%; <em>P</em> <!--><<!--> <!-->.0001). The cumulative waiting list decreased from 4,606 to 1,684 patients (−64%; 95%CI, 61.7%–66.3%; <em>P</em> <!--><<!--> <!-->.0001).</div></div><div><h3>Conclusions</h3><div>Implementation of the Quixote® tele-ophthalmology programme is a cost-efficient strategy for delivering ophthalmological care. It improves patient throughput from primary care, reduces waiting lists, optimizes hospital resources, and facilitates early detection of relevant diseases.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 9","pages":"Article 502589"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}