A. Robles García , Y. Fernández Barrientos , J.L. Ramos Navarro , J. Díaz Bernal , J. Mora Castilla , J. Ortega Usobiaga
{"title":"屈光手术后的中央毒性角膜病:诊断、治疗和临床实践中的挑战","authors":"A. Robles García , Y. Fernández Barrientos , J.L. Ramos Navarro , J. Díaz Bernal , J. Mora Castilla , J. Ortega Usobiaga","doi":"10.1016/j.oftal.2024.12.005","DOIUrl":null,"url":null,"abstract":"<div><div>Central toxic keratopathy (CTK) is a rare, non-inflammatory complication that can arise after LASIK surgery. It typically presents between days3 and 9 postoperatively, characterized by central corneal opacification, stromal thinning, and a hyperopic shift. In this clinical case, a 34-year-old patient with a history of cutaneous B-cell lymphoma developed CTK in the right eye after undergoing excimer laser refractive surgery. The diagnostic process and clinical evolution of the condition under conservative treatment are detailed. Different theories regarding the pathophysiology of CTK are also presented, highlighting the importance of differential diagnosis with diffuse lamellar keratitis (DLK) and its therapeutic implications to minimize visual sequelae.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 5","pages":"Pages 278-282"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Queratopatía central tóxica tras cirugía refractiva: diagnóstico, tratamiento y retos en la práctica clínica\",\"authors\":\"A. Robles García , Y. Fernández Barrientos , J.L. Ramos Navarro , J. Díaz Bernal , J. Mora Castilla , J. Ortega Usobiaga\",\"doi\":\"10.1016/j.oftal.2024.12.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Central toxic keratopathy (CTK) is a rare, non-inflammatory complication that can arise after LASIK surgery. It typically presents between days3 and 9 postoperatively, characterized by central corneal opacification, stromal thinning, and a hyperopic shift. In this clinical case, a 34-year-old patient with a history of cutaneous B-cell lymphoma developed CTK in the right eye after undergoing excimer laser refractive surgery. The diagnostic process and clinical evolution of the condition under conservative treatment are detailed. Different theories regarding the pathophysiology of CTK are also presented, highlighting the importance of differential diagnosis with diffuse lamellar keratitis (DLK) and its therapeutic implications to minimize visual sequelae.</div></div>\",\"PeriodicalId\":8348,\"journal\":{\"name\":\"Archivos De La Sociedad Espanola De Oftalmologia\",\"volume\":\"100 5\",\"pages\":\"Pages 278-282\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archivos De La Sociedad Espanola De Oftalmologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0365669124002260\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos De La Sociedad Espanola De Oftalmologia","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0365669124002260","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Queratopatía central tóxica tras cirugía refractiva: diagnóstico, tratamiento y retos en la práctica clínica
Central toxic keratopathy (CTK) is a rare, non-inflammatory complication that can arise after LASIK surgery. It typically presents between days3 and 9 postoperatively, characterized by central corneal opacification, stromal thinning, and a hyperopic shift. In this clinical case, a 34-year-old patient with a history of cutaneous B-cell lymphoma developed CTK in the right eye after undergoing excimer laser refractive surgery. The diagnostic process and clinical evolution of the condition under conservative treatment are detailed. Different theories regarding the pathophysiology of CTK are also presented, highlighting the importance of differential diagnosis with diffuse lamellar keratitis (DLK) and its therapeutic implications to minimize visual sequelae.
期刊介绍:
La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.