Archivos De La Sociedad Espanola De Oftalmologia最新文献

{"title":"Riesgo de colonización conjuntival por bacterias cefuroxima-resistentes en la cirugía de cataratas de pacientes menores de 75 años y en los de esa edad o mayor","authors":"J.L. Urcelay-Segura ,&nbsp;J.M. Bellón-Cano ,&nbsp;T. Cuesta-Rodríguez ,&nbsp;M.E. Fernández-Rubio","doi":"10.1016/j.oftal.2025.06.004","DOIUrl":"10.1016/j.oftal.2025.06.004","url":null,"abstract":"<div><h3>Background and objective</h3><div>Bacteria isolated in postoperative endophthalmitis (PE) were reduced to cefuroxime-resistant bacteria in cataract surgery with intracameral cefuroxime as prophylaxis; age &gt;<!--> <!-->84 years was at risk for PEs caused by Gram-negative-bacteria and Staphylococci; no risks were identified for Enterococci, the most abundant isolations. The prevalence of Enterococci in the preoperative conjunctiva was associated with age<!--> <!-->&gt;<!--> <!-->74 years, diabetes, obesity, and dacryocystorhinostomy-history (DCR-history). The aim of the study is to differentiate the risk of age from that of other patient characteristics, establishing 2 different age groups.</div></div><div><h3>Materials and methods</h3><div>We conducted a retrospective cross-sectional study in a tertiary referral center. In 7,085 patients &lt;<!--> <!-->75 years old and 7,798 ≥<!--> <!-->75 years, the incidence rate ratio (IRR) of Enterococci, Enterobacteriaceae, Non-fermentative-Gram-negative-bacilli (NFGNB) and Coagulase-negative-Staphylococci (CNS) was calculated for the following factors: diabetes, obesity, DCR-history, sex-male, smoking-habit, and climate, using multivariate Poisson regression, IBM SPSS Statistic for Windows, version 25.0. Armonk, NY: IBM Corp.</div></div><div><h3>Results</h3><div>Diabetes, obesity, male-sex and smoking-habit were more prevalent in patients &lt;<!--> <!-->75 years old. The IRRs of Enterococci, Enterobacteriaceae and NFGNB were higher in this age group: [Enterococci IRRs: diabetes, 1.54 vs 1.42; obesity, 2.95 vs 1.50; DCR-history, 3.78 vs 1.08]; [Enterobacteriaceae IRRs: diabetes, 1.47 vs 1.13; obesity, 2.27 vs 1.99; male-sex, 1.76 vs 1.65]; [NFGNB IRRs: diabetes, 1.79 vs 1.16; autumn-weather, 2.05 vs 1.56]. Diabetes-obesity simultaneously: Enterobacteriaceae IRR, 3.30 vs 2.28; Enterococci IRR, 3.28 vs 1.62.</div></div><div><h3>Conclusions</h3><div>Diabetes, obesity and DCR-history increase the IRR of Enterococci, Enterobacteriaceae and NFGNB in patients &lt;<!--> <!-->75 years more than they actually do in patients ≥ 75.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 592-600"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manejo oftalmológico en el síndrome de KID: experiencia clínica a largo plazo","authors":"R. Estévez-Domínguez ,&nbsp;C. Rocha-de-Lossada ,&nbsp;M. Rodríguez-Calvo-de-Mora ,&nbsp;J. Etxebarria-Ecenarro ,&nbsp;J. García-Montesinos-Gutiérrez","doi":"10.1016/j.oftal.2025.05.002","DOIUrl":"10.1016/j.oftal.2025.05.002","url":null,"abstract":"<div><div>Keratitis-ichthyosis-deafness (KID) syndrome is a rare disease caused by mutations in the GJB2 gene. This gene encodes the protein connexin 26, which is essential for gap junctions in the epidermis, inner ear and corneal epithelium. Clinically, it is characterised by dermal hyperkeratotic lesions, sensorineural deafness and chronic keratitis that is difficult to manage. We describe two siblings diagnosed with KID syndrome who were followed up in our department for more than 15 years. Both developed numerous ocular complications associated with chronic keratitis and limbar insufficiency that required multiple keratoplasties, systemic immunosuppression and even keratoprosthesis. This case is noteworthy for the long-term follow-up of this condition and the difficult ocular management, highlighting the importance of a multidisciplinary approach and personalised therapeutic strategies.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 625-629"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isquemia macular tras perforación inadvertida del globo ocular e inyección intravítrea de anestésicos durante una anestesia retrobulbar","authors":"J.L. Sánchez-Vicente,&nbsp;M. Portillo-Martínez,&nbsp;J.V. Guijarro-Ambel,&nbsp;E.M. Gámez-Jiménez,&nbsp;E. Cosano-Palma,&nbsp;F. López-Herrero","doi":"10.1016/j.oftal.2025.05.003","DOIUrl":"10.1016/j.oftal.2025.05.003","url":null,"abstract":"<div><div>Perforation of the eyeball during retrobulbar anesthesia is rarely reported. A case of inadvertent ocular perforation during retrobulbar anesthesia in cataract surgery is presented. Retinal complications and follow up after six months are described.</div><div>A 58-year-old man presented with vision loss following cataract surgery on his right eye by phacoemulsification and intraocular lens implantation under retrobulbar anaesthesia performed one week earlier. Visual acuity was 0.05. Fundus examination revealed a vitreous haemorrhage in the lower area. A rounded haemorrhage was present next to the lower temporal arcade with a possible entry orifice. Optical coherence tomography, tomographic angiography and fluorescein angiography showed retinal ischaemia in the juxtapapillary macular area.</div><div>The patient was followed for 6 months. Visual acuity improved to 0.5. Optical coherence tomography and tomographic angiography showed a reduction of the edema in the retinal layers, with a persistent loss of the inner nuclear and outer plexiform layer</div><div>Accidental intravitreal injection of bupivacaine and lidocaine during retrobulbar anaesthesia can result in permanent visual impairment. Extreme attention should be paid to the injection technique to avoid this complication.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 630-635"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inteligencia artificial y telemedicina en oculoplastia: avances recientes, aplicaciones clínicas y desafíos emergentes","authors":"F. Calleja Casado ,&nbsp;A. Caro Ortega ,&nbsp;E. Gracia Rovira ,&nbsp;A. Duch Samper","doi":"10.1016/j.oftal.2025.06.013","DOIUrl":"10.1016/j.oftal.2025.06.013","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 650-651"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinosis pigmentaria autosómica dominante: informe de una familia extensa con la variante Asp-190-Tyr","authors":"P. Moreira-Martins,&nbsp;C. Ferreira,&nbsp;E. Saraiva,&nbsp;P. Sepúlveda,&nbsp;L. Silva,&nbsp;F. Sousa-Neves","doi":"10.1016/j.oftal.2025.06.002","DOIUrl":"10.1016/j.oftal.2025.06.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Retinitis pigmentosa (RP) represents a spectrum of rod-cone inherited disorders with characteristic symptoms, and functional changes. The Asp-190-Tyr pathogenic variant of the <em>RHO</em> gene impairs rodopsin transport through the endoplasmic reticulum, leading to accumulation within photoreceptors, inducing cytotoxicity. This report presents the ophthalmologic phenotype of this rare variant.</div></div><div><h3>Materials and Methods</h3><div>Retrospective study including patients from one extended family presenting with RP, with an autosomal dominant variant of the <em>RHO</em> gene (Asp-190-tyr). Baseline demographic/ophthalmologic data and ancillary testing was collected.</div></div><div><h3>Results</h3><div>Twelve individuals were included; eight had generalized RP. The mean age was 64 years - four were female. Genetic testing in 5/8 patients with RP revealed an autosomal dominant variant in the <em>RHO</em> gene, with replacement of an aspartic acid with tyrosine at codon 190. Visual acuity ranged from no light perception to 6/10. Fundoscopy and fundus autofluorescence showed bilateral generalized RP pattern: optic disc pallor, bone spicules, and arterial narrowing. Perimetry in four patients showed tunnel vision. Electrophysiology revealed marked wave reduction in both pattern and flash ERG. Severe atrophy of the outer retinal layers with cystoid macular oedema was observed in 4/8 patients.</div></div><div><h3>Conclusions</h3><div>This study highlights the phenotype of the Asp-190-Tyr variant. Previously, it was described in a family with a regional pattern of RP and relatively preserved visual function. Our study changes this paradigm, with patients presenting with a generalized RP phenotype and significant visual impairment. The provided data may help offer accurate prognostic information to patients with this variant.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 585-591"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación oculomotora automatizada en el glaucoma congénito primario mediante un dispositivo DIVE: un estudio piloto de fijación, seguimiento ocular y movimientos sacádicos","authors":"L. Morales-Fernandez,&nbsp;C. Heredia-Pastor,&nbsp;P. Talavero,&nbsp;I. Collado,&nbsp;J. Garcia-Feijoo,&nbsp;R. Gomez-de-Liaño","doi":"10.1016/j.oftal.2025.06.016","DOIUrl":"10.1016/j.oftal.2025.06.016","url":null,"abstract":"<div><h3>Purpose</h3><div>Primary congenital glaucoma (PCG) is a significant cause of childhood vision loss. While visual acuity can be measured, it does not always reflect visual functioning in daily life, particularly as oculomotor skills are often compromised in ocular disorders. This pilot study assesses oculomotor behavior in children with PCG compared to healthy peers using the device for an integral visual examination.</div></div><div><h3>Methods</h3><div>Twelve children with PCG (n<!--> <!-->=<!--> <!-->24 eyes) and 24 healthy children (n<!--> <!-->=<!--> <!-->48 eyes), aged 6 months to 4 years, were recruited. The device for an integral visual examination was used for automated oculomotor assessments, measuring fixation (gaze stability, fixation stability, and duration of fixation), saccadic movements (reaction time, peak velocity), and smooth pursuit (latency, gain).</div></div><div><h3>Results</h3><div>PCG children showed significantly poorer gaze stability in both short (0.68 log degree² [0.29 to 0.94] vs. 0.15 log degree² [−0.17 to 0.59]; p<!--> <!-->&lt;<!--> <!-->0.05) and long tasks (1.08 log degree² [0.79 to 1.84] vs. 0.57 log degree² [0.30 to 0.85]; p<!--> <!-->&lt;<!--> <!-->0.05), and poorer fixation stability in short (−0.20 log degree² [−0.27 to −0.17] vs. −0.48 log degree² [−0.55 to −0.30]; p<!--> <!-->&lt;<!--> <!-->0.05) and long tasks (−0.11 log degree² [−0.20 to −0.04] vs. −0.41 log degree² [−0.57 to −0.26]; p<!--> <!-->&lt;<!--> <!-->0.05). Fixation durations were shorter, and saccadic reaction times were longer in the PCG group, while pursuit latency showed no significant difference (p<!--> <!-->=<!--> <!-->0.8118).</div></div><div><h3>Conclusions</h3><div>Children with PCG have significantly impaired oculomotor behavior, including greater instability in gaze and fixation, shorter fixation durations, and longer saccadic reaction times compared to healthy peers.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 610-617"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esotropía aguda durante una queratoconjuntivitis adenovírica","authors":"J. Moya-Roca ,&nbsp;M. Lledó-Riquelme ,&nbsp;E. Campos-Mollo ,&nbsp;J. Hernández-Jiménez ,&nbsp;C. Porcar-Plana ,&nbsp;M. Lledó-Carreres ,&nbsp;E. Navarro-Hernández","doi":"10.1016/j.oftal.2025.01.014","DOIUrl":"10.1016/j.oftal.2025.01.014","url":null,"abstract":"<div><div>Acute acquired comitant esotropia is a rare manifestation of strabismus that has been used to describe an acute late-onset of esotropia with diplopia in a previously orthotropic individual. It often occurs in older children and adults and has been associated with multiple etiologies. Despite the multiple reports conducted its cause is still controversial. We describe a young patient with epidemic keratoconjunctivitis with an acute comitant esotropia. He had no underlying diseases and regained stereo acuity after surgical alignment of both eyes.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 640-643"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La conceptualización de los «líderes clave en evidencia» a partir de los «líderes de opinión»: una revisión también aplicable en oftalmología","authors":"J. Fernández ,&nbsp;F. Ribeiro ,&nbsp;H.B. Dick ,&nbsp;T. Kohnen ,&nbsp;C. Rocha-de-Lossada ,&nbsp;M. Rodríguez-Vallejo","doi":"10.1016/j.oftal.2025.02.010","DOIUrl":"10.1016/j.oftal.2025.02.010","url":null,"abstract":"<div><div>The collaboration of ophthalmologists with the industry, in their role as opinion leaders (OLs) who interpret, modify, and disseminate information to professional networks, is susceptible to bias. This review explores the critical role of OLs in the healthcare industry and their evolution into Key Evidence Leaders (KELs), emphasizing the importance of differentiating KELs from traditional OLs to promote evidence-based practices and maintain research integrity in healthcare. OLs often rely on their reputation and experience, which can make them susceptible to industry biases, particularly when financial incentives are involved. The concept of KELs marks a significant evolution from traditional OLs. Unlike OLs, KELs base their influence on expertise in clinical evidence and research, rather than personal experience or industry affiliations. KELs possess strong analytical skills, engage in interdisciplinary collaboration, and emphasize transparency and unbiased dissemination of information. The emergence of KELs represents a significant shift towards evidence-based leadership in healthcare. Differentiating KELs from traditional OLs is crucial for ensuring that the messages received by healthcare professionals are less biased. By supporting KELs who prioritize patient-centered evidence, the industry can enhance trust in the application of medical devices and drugs.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 618-624"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disfunción visual progresiva y neurodegeneración retiniana en pacientes con fibromialgia","authors":"E. Garcia-Martin ,&nbsp;M.J. Vicente Altabás ,&nbsp;E. Vilades Palomar ,&nbsp;E. Orduna Hospital ,&nbsp;B. Cordon Ciordia ,&nbsp;J. Garcia-Campayo ,&nbsp;M. Puebla-Guedea ,&nbsp;M. Satue Palacian","doi":"10.1016/j.oftal.2025.06.015","DOIUrl":"10.1016/j.oftal.2025.06.015","url":null,"abstract":"<div><h3>Background</h3><div>Pathophysiology of fibromyalgia is still not well known. There are certain theories than point out a possible neurodegeneration component.</div></div><div><h3>Objectives</h3><div>To evaluate variations in visual function parameters and in the macular ganglion cell layer (CGR) of patients with Fibromyalgia (FM) over a period of 5 years, and compare these results with controls.</div></div><div><h3>Method</h3><div>85 patients with FM and 41 healthy subjects underwent a complete ophthalmic evaluation, including assessment of visual acuity (VA) with ETDRS, contrast sensitivity vision (CSV) with Pelli Robson, color vision with Farnsworth and Lanthony D15 tests and retinal evaluation using Cirrus HD-OCT 3000 (Carl Zeiss, California). All subjects were re-evaluated after 5 years. It was also analysed the association between progressive structural, functional and disease severity changes. Furthermore, patients were classified into three groups (1, atypical; 2, depressive; 3, biologic).</div></div><div><h3>Results</h3><div>Progressive changes were detected in visual function parameters and CGR thickness in FM patients after 5 years. Patients with FM presented worse low contrast VA (p<!--> <!-->=<!--> <!-->0.022), color discrimination (Lanthony's C index, p<!--> <!-->=<!--> <!-->0.006) and decreased CGR thickness (nasal inferior, p<!--> <!-->&lt;<!--> <!-->0.001) over the follow up time, compared with controls. Changes in color vision were associated with CGR thinning, but no correlations with disease severity were observed.</div></div><div><h3>Conclusions</h3><div>It has been noticed progressive visual dysfunction and CGR loss in patients suffering from FM. The analysis of visual function parameters and CGR thickness using Cirrus OCT could be of value to control FM disease.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 601-609"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conexión molecular entre la superficie ocular y el inflamasoma. Nuevas perspectivas diagnósticas y terapéuticas","authors":"S. Mora-Sáez ,&nbsp;I. Andrés-Blasco ,&nbsp;J. Benítez-del-Castillo-Sánchez ,&nbsp;V. Zanón-Moreno ,&nbsp;C. Peris-Martínez ,&nbsp;M.D. Pinazo-Durán","doi":"10.1016/j.oftal.2025.07.001","DOIUrl":"10.1016/j.oftal.2025.07.001","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 10","pages":"Pages 581-584"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145229818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}