M.C. Baserga, M. Biga, G. Morocho Hermosa, S. Vivante, M. Clementi, J.P. Aldecoa
{"title":"Neuropatía óptica isquémica posterior (PION) secundaria a hemorragia orbitaria aguda: reporte de un caso y revisión de la literatura","authors":"M.C. Baserga, M. Biga, G. Morocho Hermosa, S. Vivante, M. Clementi, J.P. Aldecoa","doi":"10.1016/j.oftal.2026.502588","DOIUrl":"10.1016/j.oftal.2026.502588","url":null,"abstract":"<div><div>We present a case and literature review regarding posterior ischemic optic neuropathy (PION) in the context of orbital hemorrhage following cosmetic blepharoplasty. A 49-year-old male patient, who underwent resection of residual fat from a previous blepharoplasty, developed acute orbital hemorrhage six hours postoperatively, with sudden visual loss, painful proptosis, and a relative afferent pupillary defect. Urgent decompressive surgery was performed. Ultimately, the patient did not experience visual improvement, and optic atrophy was evident one month later, confirming the diagnosis of PION. Potential pathophysiological mechanisms include direct nerve compression, venous stasis, epinephrine-induced vasoconstriction, vascular steal phenomena, orbital fat traction, and alterations in coagulation and blood pressure. The various hemodynamic, orbital, and systemic mechanisms demonstrate the importance of considering PION as a possible cause of acute visual loss after eyelid procedures.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502588"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Melgar Martín, M.I. Soler Sanchis, L. Pérez Zaballos, R. Calvo Andrés, L. Mata Moret, E. Cervera Taulet
{"title":"Amiloidosis conjuntival AL como manifestación inicial de mieloma múltiple","authors":"S. Melgar Martín, M.I. Soler Sanchis, L. Pérez Zaballos, R. Calvo Andrés, L. Mata Moret, E. Cervera Taulet","doi":"10.1016/j.oftal.2026.502556","DOIUrl":"10.1016/j.oftal.2026.502556","url":null,"abstract":"<div><div>Conjunctival amyloidosis is an uncommon entity, generally primary and localized, that should be considered in the differential diagnosis of conjunctival lesions. We present the case of a 74-year-old man with no relevant medical history who, during follow-up after cataract surgery, developed elevated yellowish-salmon conjunctival plaques. Incisional biopsy revealed subepithelial amyloid deposits, positive for Congo red and immunohistochemistry consistent with AL amyloidosis with kappa light chain restriction. The initial systemic evaluation was normal; however, clinical progression led to the diagnosis of multiple myeloma with multisystemic involvement. Systemic treatment did not reduce the size of the conjunctival lesions, but topical cyclosporine improved ocular discomfort and the sensation of a foreign body. This case highlights the role of the ophthalmologist in the early detection of systemic diseases. Histological confirmation is essential, and although there is no specific treatment, symptomatic management and multidisciplinary follow-up improve the patient's quality of life.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502556"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Martínez Serna, P. Navarro Torres, A. Romero Titos
{"title":"Degeneración nodular tipo Salzmann asociada al uso de isotretinoína sistémica en un adulto joven","authors":"V. Martínez Serna, P. Navarro Torres, A. Romero Titos","doi":"10.1016/j.oftal.2026.502563","DOIUrl":"10.1016/j.oftal.2026.502563","url":null,"abstract":"<div><div>A 19-year-old male undergoing systemic isotretinoin therapy presented with bilateral corneal nodules resembling Salzmann nodular degeneration (SND). He had no prior ocular comorbidities and reported mild itching. Slitlamp examination revealed inflammatory nodules with pannus and blepharitis; optical coherence tomography (OCT) confirmed no stromal involvement. Systemic retinoid therapy was discontinued, and topical antiinflammatory treatment initiated. Despite transient visual decline, the patient improved over six months, with resolution of symptoms and stabilization of the corneal lesions. The temporal relationship between isotretinoin use and lesion onset, in the absence of other risk factors, suggests a possible association between systemic retinoids and SND-like pathology. This case highlights the importance of ophthalmologic monitoring in patients on retinoid therapy and raises awareness of potential corneal complications.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502563"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"¿Influyen las características del nombre en el número de citas en oftalmología?","authors":"M.E. Kapsetaki","doi":"10.1016/j.oftal.2026.502575","DOIUrl":"10.1016/j.oftal.2026.502575","url":null,"abstract":"<div><div>This study examined whether name characteristics influence citation counts in ophthalmology. This was done by assessing 5,407 papers published between 2015 and 2020 in four ophthalmology journals. Analyses of first and last authors’ names considered factors such as length, consonant sequences, alphabetical order, and popularity. After controlling for the year of publication, the number of authors, and the type of publication, only one association was found to be statistically significant; specifically, that the longer a consonant sequence was in the first-author's forename the more citations their publication received. Future research could address broader datasets and additional academic outcomes.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502575"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. de-Juan-Hernández, M.E. García-Lagarto, V.M. Asensio-Sánchez
{"title":"Amiloidosis del párpado y la conjuntiva","authors":"L. de-Juan-Hernández, M.E. García-Lagarto, V.M. Asensio-Sánchez","doi":"10.1016/j.oftal.2026.502492","DOIUrl":"10.1016/j.oftal.2026.502492","url":null,"abstract":"<div><div>Amyloidosis is characterized by the extracellular deposition of abnormal amyloid protein fibrils in tissues. Amyloidosis of the eyelid and conjunctiva (AEC) is a rare clinical finding. We present the case of a 48-year-old female patient with pinkish-yellow infiltration in the upper and lower bulbar conjunctiva, along with a firm, well-circumscribed nodular lesion on the lower eyelid of the right eye. Biopsies of the eyelid and conjunctiva were performed, and histological examination confirmed amyloid deposition with Congo red staining. AEC is a rare entity that is often underdiagnosed. Although it most frequently manifests as a localized process, systemic involvement must always be ruled out.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502492"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Platas Moreno, P. Drake Rodríguez-Casanova, J.J. Dominguez Cañete
{"title":"Desafíos diagnósticos y terapéuticos del glaucoma en un paciente con fenilcetonuria: caso clínico y revisión","authors":"I. Platas Moreno, P. Drake Rodríguez-Casanova, J.J. Dominguez Cañete","doi":"10.1016/j.oftal.2026.502577","DOIUrl":"10.1016/j.oftal.2026.502577","url":null,"abstract":"<div><div>Phenylketonuria is a metabolic disorder in which structural retinal alterations have been reported and may interfere with the interpretation of diagnostic tests for glaucoma.</div><div>We report the case of a 59-year-old woman with phenylketonuria who was under follow-up for suspected glaucoma and presented with an intraocular pressure of 22<!--> <!-->mmHg in the right eye and 50<!--> <!-->mmHg in the left eye. Optical coherence tomography showed thinning of the retinal nerve fiber layer in the inferior sector, without corresponding visual field defects. Despite maximal medical therapy—adjusted in light of her systemic condition—adequate intraocular pressure control was not achieved, and the patient required phacoemulsification combined with non-penetrating deep sclerectomy.</div><div>This case underscores the need for an individualized approach to the diagnosis and follow-up of glaucoma in patients with phenylketonuria, as well as heightened caution in therapeutic management.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502577"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Dimitrova, A. Gjorgjiovska, A. Ljubic, S.M. Jordanovska
{"title":"Efecto de la ansiedad preoperatoria y perioperatoria sobre los parámetros cardiovasculares y la presión intraocular en pacientes que esperan cirugía de facoemulsificación","authors":"G. Dimitrova, A. Gjorgjiovska, A. Ljubic, S.M. Jordanovska","doi":"10.1016/j.oftal.2026.502610","DOIUrl":"10.1016/j.oftal.2026.502610","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>To evaluate pre- and perioperative anxiety in patients scheduled for cataract surgery and to assess its correlation with cardiovascular parameters and intraocular pressure (IOP).</div></div><div><h3>Patients and methods</h3><div>Thirty cataract surgery patients were included. Exclusion criteria included previous ocular surgery, glaucoma, and ocular inflammation. Anxiety levels were assessed using a visual facial anxiety scale (VFAS). Systemic blood pressure (BP), heart rate (HR), and IOP were measured using a sphygmomanometer and an air-puff tonometer, with mean values calculated from three readings. VFAS, BP, HR, and IOP were recorded during the pre- and perioperative periods. A t-test compared parameters, and Pearson's coefficient was used to analyze correlations.</div></div><div><h3>Results</h3><div>Patients reported mild to moderate anxiety during both the pre- and perioperative periods. Cardiovascular parameters and IOP showed no significant differences between the two periods. IOP correlated significantly with HR perioperatively (R=0.62, P<0.001) and with systolic BP preoperatively (R=0.47, P=0.009). Preoperatively, patients with moderate to high anxiety had higher IOP (17.06±1.69<!--> <!-->mmHg) than those with no to mild/moderate anxiety (14.74±2.41<!--> <!-->mmHg; P =0.006).</div></div><div><h3>Conclusions</h3><div>Higher anxiety levels increase IOP preoperatively. Assessing BP, HR, and IOP, as well as alleviating anxiety may improve surgical outcomes and ensure stress-free procedures.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502610"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149072072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regresión de mancha de Bitot tras suplementación con vitamina A","authors":"J. Molina García","doi":"10.1016/j.oftal.2026.502613","DOIUrl":"10.1016/j.oftal.2026.502613","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502613"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V.T. Pérez-Torregrosa, A. Caro-Ortega, I. Pérez-Cantó, Á. Ojeda-Parot, J. Pérez-Martínez, E. Gracia-Rovira, M. Huerta-Morales, A. Cabrera-Peset, A. Duch-Samper
{"title":"Eficacia y seguridad a 12 meses de PRESERFLO® asociado a DuraGen® y evaluación morfológica mediante OCT-SA","authors":"V.T. Pérez-Torregrosa, A. Caro-Ortega, I. Pérez-Cantó, Á. Ojeda-Parot, J. Pérez-Martínez, E. Gracia-Rovira, M. Huerta-Morales, A. Cabrera-Peset, A. Duch-Samper","doi":"10.1016/j.oftal.2026.502617","DOIUrl":"10.1016/j.oftal.2026.502617","url":null,"abstract":"<div><h3>Background and objective</h3><div>To evaluate the efficacy and safety at 12 months of PRESERFLO® implantation combined with 0.04% MMC and the interposition of DuraGen® in patients with moderate or severe glaucoma, and to analyse bleb morphology using anterior segment optical coherence tomography (AS-OCT).</div></div><div><h3>Material and methods</h3><div>Prospective study including 50 eyes that underwent PRESERFLO® implantation with 0.04% MMC and DuraGen®, either as a standalone procedure or combined with cataract surgery. Complete success was defined as achieving an intraocular pressure (IOP) between 5 and 18<!--> <!-->mmHg without topical hypotensive treatment, qualified success when this range was achieved with treatment, and failure when these criteria were not met. Postoperative complications and bleb morphology were assessed using AS-OCT. In addition, a comparative subanalysis between standalone and combined surgery was performed.</div></div><div><h3>Results</h3><div>Mean preoperative IOP was 26.8<!--> <!-->±<!--> <!-->7.1<!--> <!-->mmHg and decreased to 13.1<!--> <!-->±<!--> <!-->4.5<!--> <!-->mmHg, representing a mean reduction of 47.9% (p <<!--> <!-->0.001). Complete success was achieved in 42 eyes (84%), qualified success in 5 eyes (10%), and failure was observed in 3 eyes (6%). The most frequent complication was choroidal detachment (22%). No significant differences were observed between standalone and combined surgery regarding final IOP or surgical success rates. In successful cases, AS-OCT more frequently showed a suprascleral aqueous lake, whereas failed cases presented a flat bleb.</div></div><div><h3>Conclusions</h3><div>PRESERFLO® implantation combined with 0.04% MMC and DuraGen® was effective and safe for IOP control at 12 months. AS-OCT allows identification of morphological patterns associated with success and failure.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502617"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Luz azul y melatonina: revisión crítica de la evidencia científica y los mitos biohackers en oftalmología","authors":"C. Campo-Beamud, G. Roig-Ferreruela","doi":"10.1016/j.oftal.2026.502590","DOIUrl":"10.1016/j.oftal.2026.502590","url":null,"abstract":"<div><div>Blue light has been associated with potential effects on visual function, sleep, and circadian physiology, although clinical evidence remains heterogeneous. In recent years, dissemination of claims unsupported by clinical evidence regarding spectral filters for preventive purposes has increased. The aim of this review was to critically analyze the available scientific evidence on the visual, circadian, and systemic effects of blue light and contrast it with messages disseminated through media and social networks.</div><div>A narrative review of the literature published between 2009 and 2025 was conducted using PubMed, Scopus, and the Cochrane Library, prioritizing human studies and institutional position statements relevant to ophthalmological practice.</div><div>Available systematic reviews and controlled trials indicate that blue-filtering lenses do not provide clinically meaningful improvements in visual acuity or symptoms of digital eye strain, and show small and inconsistent effects on sleep-related outcomes. Under typical viewing conditions, screen light exposure remains well below levels associated with photochemical retinal damage in experimental models. Therefore, current evidence does not support the routine preventive or therapeutic use of blue-blocking glasses. The most effective strategies rely on light hygiene, reduction of nocturnal light exposure, and patient education.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"101 10","pages":"Article 502590"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149071590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}