Cambios endoteliales en pacientes con y sin diabetes después de cirugía manual de catarata de pequeña incisión

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia Pub Date : 2025-05-01 DOI:10.1016/j.oftal.2025.01.011

L.A. Oseguera Chávez, L.E. Salas Medina, C. Palacio Pastrana, W. Cedillo Suárez

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Abstract

Background and objective

In Mexico there is a high prevalence of diabetes, which is one of the most frequent etiologies of cataract. The impact of diabetes on postoperative corneal decompensation associated with MSICS has not been studied in our country. The objective of the study was to determine the difference in corneal endothelial changes between diabetic and non-diabetic patients by preoperative specular microscopy and at one month and 3 months after MSICS.

Patients and methods

Prospective, longitudinal, paired, non-randomized study with two groups; Group 1: Diabetic patients and Group 2: Non-diabetic patients. All patients had a complete ophthalmologic evaluation and preoperative and postoperative specular microscopy at one month and 3 months.

Results

119 eyes were included. The percentage of CD loss at 1 month was 11.1% in diabetic patients and 6.3% in non-diabetic patients. At 3 months the percentage of loss was 9.9% in diabetic patients and 5.4% in non-diabetic patients. The CV was higher in patients with diabetes and was significant at 1 month; however, at 3 months the values were comparable. The percentage of HEX decreased significantly in the first month in patients with diabetes.

Conclusions

There was a significant difference with greater CD loss, greater CV and less HEX in patients with diabetes vs. without diabetes at 1 month after the M-SICS procedure, however, it was not statistically significant at 3 months. This suggests greater endothelial stress, longer recovery time and remodeling of the corneal endothelium in patients with diabetes.

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手工小切口白内障手术后糖尿病患者和非糖尿病患者的内皮变化

背景与目的在墨西哥，糖尿病的患病率很高，是白内障最常见的病因之一。糖尿病对msic术后角膜失代偿的影响在国内尚未见相关研究。本研究的目的是通过术前、术后1个月和3个月的镜面显微镜观察糖尿病患者和非糖尿病患者角膜内皮变化的差异。患者和方法前瞻性、纵向、配对、非随机研究，分为两组；第一组为糖尿病患者，第二组为非糖尿病患者。所有患者在1个月和3个月时进行了完整的眼科评估和术前和术后的镜面显微镜检查。结果共纳入119只眼。1个月时，糖尿病患者的CD损失率为11.1%，非糖尿病患者为6.3%。3个月时，糖尿病患者的损失百分比为9.9%，非糖尿病患者为5.4%。糖尿病患者的CV较高，且在1个月时具有显著性；然而，在3个月时，这些值具有可比性。糖尿病患者的HEX百分比在第一个月显著下降。结论：与非糖尿病患者相比，糖尿病患者在M-SICS手术后1个月的CD损失、CV升高和HEX降低有显著差异，但在3个月时无统计学意义。这表明糖尿病患者的角膜内皮压力更大，恢复时间更长，内皮重塑时间更长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archivos De La Sociedad Espanola De Oftalmologia Medicine-Ophthalmology

CiteScore

1.20

自引率

0.00%

发文量

109

审稿时长

78 days

期刊介绍： La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.