Archives of Gynecology and Obstetrics最新文献

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Usefulness and timing of the third-trimester ultrasound scan: a review of guidelines and underlying evidence. 妊娠晚期超声扫描的有效性和时机:指南和基础证据的回顾。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-08 DOI: 10.1007/s00404-025-08172-7
Doaa Emam, Giulia Corbella, Caterina Poziello, Simona Fabozzo, Antonio Farina, Massimo Candiani, Karl Oliver Kagan, Paolo Ivo Cavoretto
{"title":"Usefulness and timing of the third-trimester ultrasound scan: a review of guidelines and underlying evidence.","authors":"Doaa Emam, Giulia Corbella, Caterina Poziello, Simona Fabozzo, Antonio Farina, Massimo Candiani, Karl Oliver Kagan, Paolo Ivo Cavoretto","doi":"10.1007/s00404-025-08172-7","DOIUrl":"https://doi.org/10.1007/s00404-025-08172-7","url":null,"abstract":"<p><strong>Objectives: </strong>Recommendations regarding the use of third-trimester ultrasound lack universal consensus. Yet, there is evidence which supports its value in assessing fetal growth, fetal well-being, and a number of pregnancy-related complications. This literature review evaluates the available scientific evidence regarding its applications, usefulness, and the timing of the third-trimester scan in a low-risk population.</p><p><strong>Methods: </strong>A literature search (PubMed, Embase, Scopus; until April 1st, 2025) identified English-language studies dealing with third-trimester ultrasound screening, its aims, and its best timing. International and national guidelines were reviewed to assess the current recommendations. Large, high-quality studies were then used to evaluate the completeness of the current recommendations and to analyze additional parameters that could be considered when assessing the usefulness of a third-trimester ultrasound screening.</p><p><strong>Results: </strong>Six international and national sets of guidelines regarding the third-trimester ultrasound were analyzed, showing wide variability in recommendations. While all six support its use, mainly for fetal growth, amniotic fluid, and placental assessment, only ISUOG and SIEOG specify the gestational age at which it should be performed (32-36 weeks). Fetal biometry and anatomy are universally suggested, while recommendations for Doppler studies, biophysical profile, and cervical length are inconsistent. Newer applications, such as pre-eclampsia screening and prediction of labor onset and intrapartum complications, are not yet included. Recent major studies in low-risk populations suggest 36-week gestation as the optimal screening time.</p><p><strong>Conclusions: </strong>There is a broad recognition of third-trimester ultrasound being useful for fetal monitoring, but consensus is lacking regarding its routine use in low-risk populations, its outcomes and timing. Major evidence supports ultrasound screening at 36-week gestation in low-risk pregnancies to predict fetal growth restriction, macrosomia, structural anomalies, complications due to placental abnormalities, pre-eclampsia and onset of labor. When preceded by effective risk stratification done earlier in pregnancy, this strategy may enhance pregnancy management potentially improving maternal-fetal outcomes.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Expression of Concern: Cyclic versus continuous medroxyprogesterone acetate for treatment of endometrial hyperplasia without atypia: a 2-year observational study. 编辑关注表达:一项为期2年的观察性研究:环与连续醋酸甲孕酮治疗无异型性子宫内膜增生。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-08 DOI: 10.1007/s00404-025-08155-8
Mohamed Emarh
{"title":"Editorial Expression of Concern: Cyclic versus continuous medroxyprogesterone acetate for treatment of endometrial hyperplasia without atypia: a 2-year observational study.","authors":"Mohamed Emarh","doi":"10.1007/s00404-025-08155-8","DOIUrl":"https://doi.org/10.1007/s00404-025-08155-8","url":null,"abstract":"","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-invasive left ventricular myocardial work indices in preterm neonates born to mothers with severe preeclampsia in pregnancy. 妊娠期重度子痫前期母亲所生早产儿的无创左室心肌功指标。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-08 DOI: 10.1007/s00404-025-08088-2
Huiyun Chen, Xiaoyu Li, Fangcan Sun, Jingjing Zhang, Weizeyu Liu, Xinran Dong, Hong Li, Qiuqin Xu, Bing Han
{"title":"Non-invasive left ventricular myocardial work indices in preterm neonates born to mothers with severe preeclampsia in pregnancy.","authors":"Huiyun Chen, Xiaoyu Li, Fangcan Sun, Jingjing Zhang, Weizeyu Liu, Xinran Dong, Hong Li, Qiuqin Xu, Bing Han","doi":"10.1007/s00404-025-08088-2","DOIUrl":"https://doi.org/10.1007/s00404-025-08088-2","url":null,"abstract":"<p><strong>Objective: </strong>The study utilized non-invasive myocardial work indices to investigate myocardial injury in infants born to mothers with severe preeclampsia (SPE) and to explore the duration of this myocardial damage during the neonatal period.</p><p><strong>Methods: </strong>This prospective study included 34 preterm infants born to mothers with SPE and 28 preterm infants born to mothers without severe pregnancy complications (termed \"controls\"). Echocardiography was performed in infants within 24 h of birth, then again at 48-72 h and 14-28 days, to obtain echocardiographic parameters. Two-dimensional speckle-tracking echocardiography (2D STE) was performed to construct a non-invasive left ventricular pressure-strain loop based on two-dimensional myocardial strain and non-invasive left ventricular systolic pressure measurements, allowing for the calculation of myocardial work indices.</p><p><strong>Results: </strong>Within 24 h after delivery, left ventricular stroke volume (SV), cardiac output (CO), and left ventricular global work index (GWI) in newborns born of mothers with SPE were significantly reduced compared to controls, while mitral E/e' and left ventricular longitudinal strain were increased. At 48-72 h after birth, mitral E/e' and left ventricular global waste work (GWW) increased, and global work efficiency (GWE) was reduced in infants of mothers with SPE. During the 14-28 days of the neonatal period, left ventricular SV and CO were reduced in the offspring of mothers with SPE and mitral E peak velocity, and E/e' and left ventricular GWW were increased.</p><p><strong>Conclusion: </strong>The adverse intrauterine environment caused by SPE can lead to persistent impaired left ventricular function in preterm infants during the neonatal period.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of fertility treatments on perinatal outcomes in pregnancies complicated by GDMA1: a comparative cohort study. 生育治疗对妊娠合并GDMA1围产儿结局的影响:一项比较队列研究
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-08 DOI: 10.1007/s00404-025-08183-4
Tamar Eshkoli, Tal Atzmon, Reut Rotem, Adi Y Weintraub, Yael Baumfeld, Naama Steiner
{"title":"Impact of fertility treatments on perinatal outcomes in pregnancies complicated by GDMA1: a comparative cohort study.","authors":"Tamar Eshkoli, Tal Atzmon, Reut Rotem, Adi Y Weintraub, Yael Baumfeld, Naama Steiner","doi":"10.1007/s00404-025-08183-4","DOIUrl":"https://doi.org/10.1007/s00404-025-08183-4","url":null,"abstract":"<p><strong>Objective: </strong>To investigate adverse pregnancy and delivery outcomes in women with GDMA1 during pregnancies conceived through fertility treatments.</p><p><strong>Methods: </strong>This population-based retrospective cohort study examined adverse pregnancy and delivery outcomes in pregnancies affected by GDMA1 following fertility treatments compared to those conceived naturally. Women with GDMA1 who conceived via fertility treatments were classified as cases, while those who conceived naturally were designated as controls. Multivariable logistic regression models were employed to evaluate the association between fertility treatments and perinatal outcomes in pregnancies complicated by GDMA1.</p><p><strong>Results: </strong>The study cohort consisted of 12,841 pregnant women diagnosed with GDMA1, of whom 640 (4.98%) conceived through fertility treatments, while the remaining 12,201 conceived naturally. Women with GDMA1 who conceived through fertility treatments had significantly higher rates of preeclampsia, hypertension, preterm birth, and cesarean delivery, while they experienced lower rates of macrosomia and polyhydramnios compared with women who conceived spontaneously. Multivariate analysis identified fertility treatments as an independent predictor of cesarean delivery, while conversely serving as a protective factor against macrosomia after adjusting for maternal age, parity, hypertensive disorders of pregnancy, and labor induction.</p><p><strong>Conclusion: </strong>Women with GDMA1 who conceived through fertility treatments experienced a reduced incidence of complications associated with GDM, such as macrosomia and polyhydramnios. This could be explained by better GDM control and adherence to a more rigorous prenatal care approach. However, they faced an increased risk of other obstetric complications, including pre-eclampsia, preterm delivery, and cesarean delivery.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Misdiagnosis in patients with obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: a retrospective study of 164 cases. 164例半阴道梗阻性伴同侧肾异常综合征的误诊分析。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-08 DOI: 10.1007/s00404-025-08170-9
Shuang Song, Zhiyuan Dou, Jiali Tong, Yiwei Zhang, Lei Li, Na Chen, Lan Zhu
{"title":"Misdiagnosis in patients with obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: a retrospective study of 164 cases.","authors":"Shuang Song, Zhiyuan Dou, Jiali Tong, Yiwei Zhang, Lei Li, Na Chen, Lan Zhu","doi":"10.1007/s00404-025-08170-9","DOIUrl":"https://doi.org/10.1007/s00404-025-08170-9","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to summarize and analyze the incidence, underlying causes and related risk factors of misdiagnosis in patients with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA) syndrome.</p><p><strong>Methods: </strong>This is a single center, retrospective study conducted in a tertiary hospital, enrolling patients diagnosed with OHVIRA syndrome in our center between January 2000 and December 2023, with intact charts retrieved. We collected information related to misdiagnosis. The main outcome was the incidence of misdiagnosis in OHVIRA patients. Misdiagnosis related information, including the primary diagnosis and following management were displayed. We also analyzed the potential risk factors of misdiagnosis in OHVIRA patients by logistic regression.</p><p><strong>Results: </strong>Among 164 cases enrolled, 27 (16.5%) patients had experienced misdiagnosis. The most frequent primary misdiagnoses were pelvic abscess (8/27, 29.6%) and ovarian cyst (7/27, 25.9%). Complicating with pelvic endometriosis was the potential risk factor of misdiagnosis (OR 3.267, 95% CI 1.010-10.660). Presenting with irregular bleeding (OR 0.193, 95%CI 0.047-0.800) and performing pelvic MRI prior to diagnosis (OR 0.157, 95% CI 0.050-0.486) were potential protective factors for misdiagnosis in patients with OHVIRA syndrome.</p><p><strong>Conclusion: </strong>Misdiagnosis is not uncommon in patients with OHVIRA syndrome. Alerting to related symptoms and optimizing various imaging modalities can effectively reduce the risk of misdiagnosis.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of hormonal contraceptives combined with vitamin D3 supplements on sexual dysfunction in women with polycystic ovary syndrome: a randomized double-blind placebo-controlled trial. 激素避孕药联合维生素D3补充剂对多囊卵巢综合征女性性功能障碍的影响:一项随机双盲安慰剂对照试验
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-06 DOI: 10.1007/s00404-025-08159-4
Shahideh Jahanian Sadatmahalleh, Fatemeh Razavinia, Razieh Lotfi, Fariba Hajimoosayi, Malihe Nasiri, Parvaneh Rezasoltani
{"title":"The effect of hormonal contraceptives combined with vitamin D3 supplements on sexual dysfunction in women with polycystic ovary syndrome: a randomized double-blind placebo-controlled trial.","authors":"Shahideh Jahanian Sadatmahalleh, Fatemeh Razavinia, Razieh Lotfi, Fariba Hajimoosayi, Malihe Nasiri, Parvaneh Rezasoltani","doi":"10.1007/s00404-025-08159-4","DOIUrl":"https://doi.org/10.1007/s00404-025-08159-4","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovary syndrome (PCOS) is characterized by reproductive and endocrine abnormalities.</p><p><strong>Objective: </strong>The present study aimed to assess the effect of oral contraceptive pills (OCPs) and vitamin D3 on sexual dysfunction in women with PCOS and vitamin D3 deficiency.</p><p><strong>Materials and methods: </strong>This randomized double-blind placebo-controlled clinical trial was conducted in Iran between January and April 2019. The Female Sexual Function Index (FSFI) and Beck Depression Inventory (BDI) questionnaires were filled out for all participants and their serum levels of vitamin D3 were measured. Women with PCOS and vitamin D3 deficiency were divided into 2 equal groups (A and B) with a table of random numbers (n = 35/ each). Both groups were given vitamin D3 (50,000 IU/w) for 12 week. The case group was given low-dose OCP for 3 months and a similar placebo was given to the control group. Vitamin D3 level and sexual function were assessed in both groups at 3 and 6 months after taking OCP.</p><p><strong>Results: </strong>There was no statistically significant difference between the two groups in demographic characteristic such as weight (69.54 ± 10.34 vs 70.17 ± 10.60, P = 0.803). Both groups treated with vitamin D3 exhibited increased sexual function scores at the beginning of the study (P = 0.03) and 3 months (P = 0.01) after taking OCP. Examination of sexual function variables showed that sexual desire in the control group was greater than in the OCP-treated group at 3 (P = 0.009) and 6 (P = 0.01) months after entering the study.</p><p><strong>Conclusion: </strong>The results of the study showed that the score of women's sexual performance increased in all areas, especially in the area of sexual desire, with the use of vitamin D3. The simultaneous use of OCP with vitamin D3 to improve sexual performance in these women had no significant difference with the use of vitamin D3 alone. According to the research findings, it is recommended that vitamin D3 supplementation can be used to increase the quality of life and improve sexual function in PCOS women.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endometrial thickness and pathology in postmenopausal women with bleeding on transdermal 17β-estradiol plus body-identical progesterone. 经皮17β-雌二醇加同体黄体酮治疗出血绝经后妇女子宫内膜厚度及病理变化。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-04 DOI: 10.1007/s00404-025-08161-w
Sarah Glynne, Aini Kamal, Amy Neville, Lynsey McColl, Osama Naji, Louise Newson, Daniel Reisel
{"title":"Endometrial thickness and pathology in postmenopausal women with bleeding on transdermal 17β-estradiol plus body-identical progesterone.","authors":"Sarah Glynne, Aini Kamal, Amy Neville, Lynsey McColl, Osama Naji, Louise Newson, Daniel Reisel","doi":"10.1007/s00404-025-08161-w","DOIUrl":"https://doi.org/10.1007/s00404-025-08161-w","url":null,"abstract":"<p><strong>Objective: </strong>The primary objective was to explore the relationship between endometrial thickness and transdermal 17β-estradiol/micronised progesterone dose in postmenopausal women with unscheduled bleeding on menopausal hormone therapy (MHT). The prevalence of endometrial pathology was also assessed.</p><p><strong>Methods: </strong>Retrospective analysis of a consecutive case series. Postmenopausal women attending a private menopause clinic were included if they presented with unscheduled bleeding on transdermal 17β-estradiol plus micronised progesterone between 1st June 2022 and 31st May 2024, and attended for an in-house ultrasound scan.</p><p><strong>Results: </strong>235 women were included (mean age 57 years, 49.37% overweight or obese). 173 women (73.62%) received on-label transdermal estradiol doses. Most women (n = 220 women, 93.62%) used continuous progesterone. On ultrasound examination, 173 women (73.62%) had a normal endometrium, 48 (20.43%) had a thickened endometrium, and 14 (5.96%) had an inadequately visualised endometrium. High BMI (> 25 kg/m<sup>2</sup>) was significantly associated with increased endometrial thickness (ET) (mean ET normal BMI vs overweight: 3.84 mm vs 4.52 mm, p = 0.07; mean ET normal BMI vs obese: 3.84 mm vs 4.50 mm, p = 0.04). There was no evidence that ET differed according to transdermal estradiol dose (on- vs off-label, p = 0.53), or by progesterone dose (low vs normal vs high, p = 0.61) or route (oral vs vaginal, p = 0.26). In multivariable analyses, there was evidence of an association between ET and MHT regimen (continuous vs sequential, p = 0.03). Amongst women with a measured serum estradiol concentration (n = 92), there was no evidence of an association between ET and serum estradiol level (p = 0.21). There were no cases of endometrial hyperplasia or cancer.</p><p><strong>Conclusions: </strong>In the study cohort, endometrial thickness in women with unscheduled bleeding on transdermal 17β-estradiol plus micronised progesterone was not associated with MHT dose. The prevalence of endometrial pathology was low, including in women using off-label estradiol doses. Our findings suggest that progesterone dose should be clinically guided for optimal efficacy and to minimise risks. More research is needed to confirm our findings and prospectively evaluate endometrial outcomes in different patient populations over longer time periods, and to enable a more personalised approach to menopause care.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrosurgical hysteroscopic metroplasty for septate uterus: a single-center retrospective analysis of safety, adhesion rates, and perioperative outcomes. 电外科宫腔镜子宫成形术治疗子宫间隔:安全性、粘连率和围手术期结果的单中心回顾性分析。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-04 DOI: 10.1007/s00404-025-08169-2
Elvin Piriyev, Sven Schiermeier, Thomas Römer
{"title":"Electrosurgical hysteroscopic metroplasty for septate uterus: a single-center retrospective analysis of safety, adhesion rates, and perioperative outcomes.","authors":"Elvin Piriyev, Sven Schiermeier, Thomas Römer","doi":"10.1007/s00404-025-08169-2","DOIUrl":"https://doi.org/10.1007/s00404-025-08169-2","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the safety, adhesion rates, and perioperative outcomes of monopolar and bipolar electrosurgical hysteroscopic metroplasty in women with a septate uterus.</p><p><strong>Methods: </strong>We conducted a single-center retrospective analysis of 155 consecutive patients who underwent same-session laparoscopy and hysteroscopic septum resection between January 2021 and January 2025. Procedures were performed under surgeon discretion using either a monopolar loop with glycine distension or a bipolar loop with isotonic Ringer's lactate. Postoperative prophylaxis against intrauterine adhesions comprised hyaluronic acid gel-with or without a copper intrauterine device-and, in selected extensive resections, a three-month estrogen-progestin regimen. Endometriosis was diagnosed laparoscopically and, when lesions were excised, confirmed histologically.</p><p><strong>Results: </strong>The most common indications for the surgery were endometriosis (40.6%), recurrent pregnancy loss (38.0%), and infertility (19.3%). Septal morphology was subseptate in 67.7%, septate in 20.0%, and complete septate in 12.2%, and bipolar energy was used in 65.1% of procedures. No uterine perforations, fluid-overload syndromes, or major hemorrhages occurred, and one case of postoperative endometritis (0.6%) was recorded. Second-look hysteroscopy, performed in 69 patients (44.5%), showed intrauterine adhesions in 3/69 (4.3%; grade I 2.9%, grade II 1.4%); residual septal tissue was observed in 50/69 (72.5%), predominantly in extensive septa. Histologically confirmed endometriosis, identified on concomitant laparoscopy, was present in 126/155 (81.3%) and did not differ across septal types (p = 0.103).</p><p><strong>Conclusions: </strong>Monopolar and bipolar electrosurgical hysteroscopic metroplasty showed a good safety profile with negligible major complications, low adhesion rates, and minimal infection. Bipolar systems further enhance safety by enabling isotonic fluid use.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes and prognostic factors in patients with synchronous endometrial and ovarian cancer. 同时性子宫内膜癌和卵巢癌患者的预后和预后因素。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-04 DOI: 10.1007/s00404-025-08164-7
Xiaofei Lu, Honglan Zhu
{"title":"Outcomes and prognostic factors in patients with synchronous endometrial and ovarian cancer.","authors":"Xiaofei Lu, Honglan Zhu","doi":"10.1007/s00404-025-08164-7","DOIUrl":"https://doi.org/10.1007/s00404-025-08164-7","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze prognostic factors and survival outcomes in patients with synchronous endometrial and ovarian cancer (SEOC) to guide clinical management.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients diagnosed with SEOC at Peking University People's Hospital between January 2004 and December 2024. Clinicopathological data were collected, and oncological outcomes, including progression-free survival (PFS) and overall survival (OS), were analyzed along with their associated prognostic factors.</p><p><strong>Results: </strong>Among 64 included patients, vaginal bleeding was the predominant presenting symptom. Thirty-six patients were diagnosed with concordant endometrioid carcinoma, which was the most common histological type. All patients underwent surgical treatment, among whom 56 received platinum-based chemotherapy postoperatively, with a platinum sensitivity rate of 67.9%. The median PFS and OS were 27 months (range 3-215) and 41 months (range 7-246), respectively. On multivariate analysis, advanced FIGO stage of ovarian cancer (HR = 2.764; 95% CI 1.169-6.536, P = 0.021) independently predicted worse PFS, while platinum resistance (HR = 6.962; 95% CI 2.052-23.619, P = 0.002) was significantly associated with reduced OS.</p><p><strong>Conclusions: </strong>In this cohort, platinum sensitivity was observed in 67.9% of cases. The advanced ovarian FIGO stage and platinum resistance independently correlated with inferior survival, underscoring the urgent need for tailored therapeutic strategies and intensified surveillance in platinum-resistant SEOC.</p>","PeriodicalId":8330,"journal":{"name":"Archives of Gynecology and Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of behavioural interventions in managing gestational weight gain in overweight and obese pregnant women: A Scoping Review. 行为干预在管理超重和肥胖孕妇妊娠期体重增加中的作用:范围综述。
IF 2.5 3区 医学
Archives of Gynecology and Obstetrics Pub Date : 2025-09-03 DOI: 10.1007/s00404-025-08144-x
Rukmini Padiyar, Jyothi Shetty, Sanya Anklesaria, T S Shwetha, Shripad Hebbar, G Shyamala, Suvarna Hebbar, Preetha Ramachandra
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