{"title":"Synthesis of cerium dioxide–calcium oxide composite antibacterial materials and their use for water treatment and dye degradation","authors":"Qianqian Guo, Wei Geng, Donghui Yang, Guanbin Wen, Qing Wang, Dong Yang, Bin Zhang","doi":"10.1111/nyas.70040","DOIUrl":"https://doi.org/10.1111/nyas.70040","url":null,"abstract":"Bacterial infections have become a major challenge to global public health security. In this study, based on the concept of green synthesis, three cerium dioxide (CeO<jats:sub>2</jats:sub>)–calcium oxide (CaO) composites (CS–CeO<jats:sub>2</jats:sub>@CaO, CT–CeO<jats:sub>2</jats:sub>@CaO, and CTD–CeO<jats:sub>2</jats:sub>@CaO) were developed using chemical hydrothermal (CS), chrysanthemum tea impregnation (CT), and residue impregnation (CTD). Eggshell‐derived calcium oxide was used as the carrier, in combination with the functional components of chrysanthemum tea and its residue extract. The antibacterial efficacy of these materials against <jats:italic>Escherichia coli</jats:italic> exceeded 90% at a concentration of 50 µg/mL, and their bactericidal performance in water remained stable after six treatment cycles. Structural characterization experiments revealed that CT and CTD composites exhibited larger specific surface areas and hierarchical pores, which enhanced bacterial adsorption via π–π* interactions. X‐ray photoelectron spectroscopy analysis indicated that Ca<jats:sup>2+</jats:sup> released from the eggshell‐derived CaO caused ionic interference, while Ce<jats:sup>3+</jats:sup>/Ce<jats:sup>4+</jats:sup> redox pairs generated reactive oxygen species, together establishing a synergistic adsorption–ion–oxidation antimicrobial mechanism. Additionally, the composites exhibited dual water treatment functions: an 80% degradation of methylene blue within 40 min and efficient biofilm removal. By valorizing waste resources (eggshells and tea residues), this work offers a sustainable approach to develop cost‐effective multifunctional materials for addressing drug‐resistant bacterial infections and remediating dye‐contaminated wastewater.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"122 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145003012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lennart Hilbert, Aaron Gadzekpo, Simon Lo Vecchio, Mona Wellhäusser, Xenia Tschurikow, Roshan Prizak, Barbara Becker, Sandra Burghart, Ewa Anna Oprzeska‐Zingrebe
{"title":"Chromatin‐associated condensates as an inspiration for the system architecture of future DNA computers","authors":"Lennart Hilbert, Aaron Gadzekpo, Simon Lo Vecchio, Mona Wellhäusser, Xenia Tschurikow, Roshan Prizak, Barbara Becker, Sandra Burghart, Ewa Anna Oprzeska‐Zingrebe","doi":"10.1111/nyas.15415","DOIUrl":"https://doi.org/10.1111/nyas.15415","url":null,"abstract":"The genome stores and processes approximately 1.5 gigabytes of encoded information. In this article, we propose that the eukaryotic genome and its adaptable three‐dimensional packing in the form of chromatin offer a valuable template for the system architecture of DNA‐based digital computers. We examine embryonic and stem cells, which exhibit distinct chromatin‐associated condensates enriched in transcription machinery. These dynamic biomolecular condensates facilitate the spatial association of genes, genomic control elements, and molecular machinery responsible for reading the genomic code. Drawing a compelling analogy to the von Neumann computer architecture—which integrates storage, processing, and memory in most electronic computers—we reflect on how the operational principles of these condensates could inspire the design of a similar architecture for future DNA computers. In particular, we describe how one could recreate such an architecture by exploiting the process of surface condensation, which underlies the formation of chromatin‐associated condensates. We conclude by reviewing our initial steps of constructing synthetic DNA nanostructures that follow the same operational principles and enable programmable surface condensation. Finally, we outline how computational methods from accelerated materials design could further advance the development of DNA computer system architectures.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"14 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145003013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should governments moralize health?","authors":"Steven R Kraaijeveld","doi":"10.1111/nyas.70030","DOIUrl":"https://doi.org/10.1111/nyas.70030","url":null,"abstract":"<p><p>Health is often moralized not only by individuals, but also by governments, which was particularly conspicuous during the COVID-19 pandemic. This paper addresses the ethics of whether governments should moralize health. It first introduces a definition of moralizing health. It then distinguishes between different ways of moralizing health that affect its moral acceptability, including negative or positive framing, as well as different potential targets toward which moralizing may be directed: (1) persons, (2) behavior, or (3) society. It concludes that targeting individual persons and behavior, especially negatively, is morally unacceptable. Positive moralizing about a healthy society by governments may be more acceptable, but important conditions remain. Governments should not single out individuals or groups and moralizing should not be excessive. Moralized health outcomes should be equally achievable by all citizens and implementation of moral frames should be grounded in robust evidence that it will bring about desired outcomes (i.e., a healthier society) without being harmful or counterproductive. In short, governments should be very cautious about moralizing health. If one of the basic tasks of governments is to protect collective health, this is all too easily undermined by undue moralizing.</p>","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric D. Shah, Austin L. Chiang, Hon Chi Yip, Jacques Marescaux, Lee Swanstrom, Rishindra M. Reddy, Pierfrancesco Visaggi, Kristle L. Lynch
{"title":"Emerging innovation, artificial intelligence, and digital technology in esophagology","authors":"Eric D. Shah, Austin L. Chiang, Hon Chi Yip, Jacques Marescaux, Lee Swanstrom, Rishindra M. Reddy, Pierfrancesco Visaggi, Kristle L. Lynch","doi":"10.1111/nyas.70031","DOIUrl":"https://doi.org/10.1111/nyas.70031","url":null,"abstract":"New medical technology and techniques provide opportunities for better, faster care for patients with esophageal diseases, spanning robotics and minimally invasive techniques, artificial intelligence, medical devices, and digital health that are changing how to diagnose and manage patients with both benign and malignant esophageal diseases. We conducted a concise narrative review of recent advances in esophagology from the perspectives of innovators and physicians alike, with an emphasis on ensuring the environment around successful innovation over the next decade. To our knowledge, this is the first innovation‐oriented review centered on the clinical field of esophagology, focusing on applicable content and knowledge gaps across the several individual domains covered in this review.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"2 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tom S. Roth, Evy van Berlo, Juan Olvido Perea‐García, Mariska E. Kret
{"title":"Bornean orangutans (Pongo pygmaeus) show an attentional bias toward a male secondary sexual trait","authors":"Tom S. Roth, Evy van Berlo, Juan Olvido Perea‐García, Mariska E. Kret","doi":"10.1111/nyas.70032","DOIUrl":"https://doi.org/10.1111/nyas.70032","url":null,"abstract":"Visual attention mechanisms help organisms prioritize evolutionarily relevant stimuli, like threats and mating opportunities. Individuals may, therefore, attend to specific facial features. In humans, it has consistently been shown that secondary sexual traits and attractive faces capture and hold attention. By contrast, evidence for such biases in nonhuman primates, especially great apes, remains scarce. To address this gap, we conducted two eye‐tracking experiments with four zoo‐housed Bornean orangutans (<jats:italic>Pongo pygmaeus</jats:italic>), a species characterized by extreme sexual dimorphism. In both experiments, we found that orangutans exhibited an attentional bias toward fully flanged males, a sexually dimorphic trait of some adult males. They not only looked longer at flanged males but were also more likely to immediately fixate on them. This suggests that great ape cognition has been shaped by sexual selection in a similar fashion to humans, where attentional biases toward masculine and attractive faces are well‐documented. At the same time, we cannot rule out the possibility that individuals attended more to flanged males due to their potential threat to both sexes. Nevertheless, by demonstrating attentional attunement to a secondary sexual trait, our findings contribute to the growing understanding of how sexually selected features influence cognition in nonhuman primates.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"42 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144928369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Social media and suicide: Empirical evidence from the quasi‐exogenous geographical adoption of Twitter","authors":"Alexis Du, Thomas Renault","doi":"10.1111/nyas.70016","DOIUrl":"https://doi.org/10.1111/nyas.70016","url":null,"abstract":"Social media usage is often cited as a potential driver behind the rising suicide rates. However, distinguishing the causal effect—whether social media increases the risk of suicide—from reverse causality, where individuals already at higher risk of suicide are more likely to use social media, remains a significant challenge. In this paper, we use an instrumental variable approach to study the quasi‐exogenous geographical adoption of Twitter and its causal relationship with suicide rates. Our analysis first demonstrates that Twitter's geographical adoption was driven by the presence of certain users at the 2007 South by Southwest (SXSW) festival, which led to long‐term disparities in adoption rates across counties in the United States. Then, using a two‐stage least squares regression and controlling for a wide range of geographic, socioeconomic, and demographic factors, we find no significant relationship between Twitter adoption and suicide rates.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"27 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144927877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microstructure and high‐cycle fatigue fracture characteristics of WC‐enhanced nickel‐based laser cladding coating","authors":"Sha Wu, Wenjun Zhang, Zenghua Liu, Xuze Wu, Ziyin Xiang, Wen Liu","doi":"10.1111/nyas.70039","DOIUrl":"https://doi.org/10.1111/nyas.70039","url":null,"abstract":"Aeroengine and powertrain components operate under elevated temperatures and cyclic loading, making them prone to fatigue failure. Laser cladding (LC) has emerged as a sustainable repair technology due to its strong metallurgical bonding and flexible processing. However, rapid thermal cycles during LC can introduce defects such as pores, cracks, and inclusions that impair fatigue performance. Ni60A alloy is widely used in LC for its excellent processability, and reinforcement with tungsten carbide (WC) enhances wear and fatigue resistance through interfacial bonding, dislocation hindrance, and the formation of hard phases. Despite advances, high‐cycle fatigue (HCF) behavior and fracture mechanisms in LC‐repaired components remain underexplored—particularly the role of WC particle size, distribution, and interaction with dislocations. This study examines tensile and HCF properties of Ni60A/25%WC laser‐clad coatings at room temperature. S–N curves were generated and fracture surfaces analyzed to understand fatigue crack initiation and propagation. Energy‐dispersive spectroscopy was used to investigate the influence of WC/W<jats:sub>2</jats:sub>C on microstructure and mechanical performance. Our findings highlight how WC particle morphology and distribution affect fatigue resistance, providing insight into fatigue failure mechanisms and establishing a foundation for improved LC repair strategies of critical components in high‐performance systems.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"28 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Al2O3/MgO‐doped, CaO‐based adsorbents for CO2 capture: A performance study","authors":"Chengzhuang Zhang, Jia Fang, Xilong Xu, Meng Zhang, Zhiqiang Han, Jianxiong Liao","doi":"10.1111/nyas.70026","DOIUrl":"https://doi.org/10.1111/nyas.70026","url":null,"abstract":"We investigated direct calcination of four precursors: calcium oxalate (CaC<jats:sub>2</jats:sub>O<jats:sub>4</jats:sub>; denoted as CaO‐1), calcium carbonate (CaCO<jats:sub>3</jats:sub>; CaO‐2), calcium <jats:sc>d</jats:sc>‐gluconate monohydrate (C<jats:sub>12</jats:sub>H<jats:sub>22</jats:sub>CaO<jats:sub>14</jats:sub>·H<jats:sub>2</jats:sub>O; CaO‐3), and a commercial calcium carbonate (CaO‐4). The effects of precursor selection on CO<jats:sub>2</jats:sub> adsorption performance were systematically compared. CaO‐1 exhibited superior initial CO<jats:sub>2</jats:sub> adsorption capacity (0.63 g/g) due to hierarchical porosity, but suffered a 38% capacity loss after 10 cycles from sintering. Al<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> doping (CaO–Al<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub>, 95/5) enhanced capacity and kinetics (0.65 g/g and 0.23 g/g·min<jats:sup>−1</jats:sup>, respectively), showing 3% and 43.75% improvements over CaO‐1, respectively, though a degradation of 33.8% occurred after 20 cycles. MgO doping (CaO–MgO, 85/15) achieved exceptional cyclic stability, retaining 93% capacity over 10 cycles (55% improvement vs. CaO‐1) via inherent sintering resistance. Characterization experiments confirmed their structural evolution: Al<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> stabilized pore networks, while MgO preserved framework integrity. The results demonstrate that precursor engineering and dopant selection critically influence adsorption kinetics versus cyclic stability trade‐offs. Optimal CaO–Al<jats:sub>2</jats:sub>O<jats:sub>3</jats:sub> (95/5) and CaO–MgO (85/15) compositions propose a kinetics–stability decoupling strategy. This dual‐dopant approach addresses calcium looping challenges by balancing rapid CO<jats:sub>2</jats:sub> capture with structural durability, providing insights for cost‐effective adsorbent optimization.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"38 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dong Cao, Xuelian Huang, Lifang Luo, Yafang Liu, Jinbei Wen, Le Zeng, Jiachong Han, Junhua Li, Yujuan Li
{"title":"Elucidating causal relationships between circulating inflammatory factors and aging traits: Transcriptomics and Mendelian randomization analyses","authors":"Dong Cao, Xuelian Huang, Lifang Luo, Yafang Liu, Jinbei Wen, Le Zeng, Jiachong Han, Junhua Li, Yujuan Li","doi":"10.1111/nyas.70019","DOIUrl":"https://doi.org/10.1111/nyas.70019","url":null,"abstract":"Chronic inflammation is epidemiologically linked to aging, but the causal roles of specific inflammatory factors remain unclear. We performed bidirectional Mendelian randomization (Bi‐MR) to assess causal relationships between 91 circulating inflammatory protein genes and aging traits, including telomere length, epigenetic clocks, frailty, cognitive function, and health span. Causal estimates were derived using inverse‐variance weighted, with MR‐Egger, weighted median, Bayesian weighted Mendelian randomization, and robust adjusted profile score (MR‐RAPS) for sensitivity analysis. MRlap assessed sample overlap, and MR‐PRESSO detected pleiotropy. Transcriptomic validation was performed using GTEx and GSE236927 datasets with CIBERSORT adjustment, followed by weighted gene coexpression network analysis and independent validation in GSE123697 and GSE237029. Twelve inflammatory factor genes showed significant forward associations, and 10 showed reverse associations after false discovery rate correction. Notable forward links included <jats:italic>CASP8</jats:italic> with health span and <jats:italic>IL1A</jats:italic> and <jats:italic>CXCL10</jats:italic> with telomere length. Reverse MR identified telomere length as a causal driver of <jats:italic>IL10</jats:italic> mRNA levels. Transcriptomic analysis confirmed <jats:italic>IL10</jats:italic> as a differentially expressed, aging‐related inflammatory gene. This study provides genetic and transcriptomic evidence supporting bidirectional causal links between inflammation and aging. <jats:italic>IL10</jats:italic> emerged as a robust candidate linking immune regulation to aging biology.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"29 1","pages":""},"PeriodicalIF":5.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: “Systemic Neutralization of TGF-\u0000 \u0000 β\u0000 $ubeta$\u0000 Attenuates Osteoarthritis”","authors":"","doi":"10.1111/nyas.70068","DOIUrl":"10.1111/nyas.70068","url":null,"abstract":"<p>Xie, L., F. Tintani, X. Wang, F. Li, G. Zhen, T. Qiu, M. Wan, J. Crane, Q. Chen & X. Cao. 2016. Systemic neutralization of TGF-<span></span><math>\u0000 <semantics>\u0000 <mi>β</mi>\u0000 <annotation>$ubeta$</annotation>\u0000 </semantics></math> attenuates osteoarthritis. In “MARROW,” ed. by M. Zaidi. <i>Ann. N.Y. Acad. Sci</i>. 1376: 53–64. https://doi.org/10.1111/nyas.13000.</p><p>In the originally published article, the authors mistakenly reused the same images in Figure 1F (third row, first column), Figure 3F (first row), and Figure 3A (first and second row). They have conducted a thorough review of their raw data and have now provided the correct images for Figure 3A and Figure 3F:</p><p></p><p>There are no other changes to the main text of the paper. This correction does not affect either the quantification of the results or the conclusions drawn in the study.</p><p>We apologize for this error.</p>","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1551 1","pages":"338-339"},"PeriodicalIF":4.8,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://nyaspubs.onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.70068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}