Annals of the New York Academy of Sciences最新文献_第8页

The pleasure of effort: Cognitive challenges trigger hedonic physiological responses 努力的乐趣认知挑战引发享乐生理反应

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-24 DOI: 10.1111/nyas.15323

Jakub Kraus, Christopher Mlynski, Franziska Hartmann, Georgia Clay, Thomas Goschke, Giorgia Silani, Veronika Job

{"title":"The pleasure of effort: Cognitive challenges trigger hedonic physiological responses","authors":"Jakub Kraus, Christopher Mlynski, Franziska Hartmann, Georgia Clay, Thomas Goschke, Giorgia Silani, Veronika Job","doi":"10.1111/nyas.15323","DOIUrl":"10.1111/nyas.15323","url":null,"abstract":"Challenging prominent neuroscientific conceptions of effort as generally aversive, recent research suggests that people can learn to seek effort. Importantly, it is unknown whether people once they learn to value effort for its instrumentality, experience pleasure when engaging in effortful tasks. In this preregistered study (N = 194), we tested the hypothesis that effort-contingent rewards in a cognitive task will induce reward-related hedonic facial responses before, during, or after effortful engagement in a subsequent non-incentivized task. The results showed that effort-contingent reward enhanced participants’ facial responses in the zygomaticus major (ZM) muscle after effort exertion (consumption phase) in the subsequent non-incentivized task, especially in high-difficulty trials. Electrical activity in the ZM was positively associated with subjective pleasure ratings in the experimental group when solving difficult trials, suggesting that it is implicitly tracking the hedonic value of effort. Our findings show that effort-contingent reward promotes effort-related reward experience, indicating that effort itself becomes intrinsically rewarding as experienced pleasure after effort exertion.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"100-111"},"PeriodicalIF":4.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143678264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In-situ responses of temperate-zone bats to climate change 温带蝙蝠对气候变化的原位响应

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-20 DOI: 10.1111/nyas.15317

Gerald Kerth, Janis M. Wolf

{"title":"In-situ responses of temperate-zone bats to climate change","authors":"Gerald Kerth, Janis M. Wolf","doi":"10.1111/nyas.15317","DOIUrl":"10.1111/nyas.15317","url":null,"abstract":"There is growing evidence that human-induced climate change poses a major threat to bats. As climate change progresses, we can only hope to mitigate its negative effects on bat populations by gaining a more comprehensive understanding of the complex interactions of all the factors involved. Drawing on recent evidence, largely from long-term field studies of individually marked bats, we discuss the multiple impacts—positive and negative—of climate change on temperate heterothermic bats and their responses to climate change in situ. For example, there is increasing evidence that warmer summers and milder winters are leading to changes in the seasonal phenology of bats, which in turn may lead to species-specific changes in demography, morphology, physiology, food availability, and roost use. We also highlight open research questions on the responses of bats to climate change. This includes better data on population trends and the underlying direct and indirect climate-related causes for changes in mortality and reproductive success. In order to assess the long-term impacts of climate change on bats, more information is needed about the relative importance of phenotypic plasticity and evolutionary adaptation in the responses of bats to climate change.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"23-34"},"PeriodicalIF":4.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15317","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143666691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-joint approach for assessing lower limb proprioception: Reliability and precision in school-aged children 多关节方法评估学龄期儿童下肢本体感觉：可靠性和精确性

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-20 DOI: 10.1111/nyas.15305

Nina Jacobs, Maud van den Bogaart, Ann Hallemans, Pieter Meyns

{"title":"Multi-joint approach for assessing lower limb proprioception: Reliability and precision in school-aged children","authors":"Nina Jacobs, Maud van den Bogaart, Ann Hallemans, Pieter Meyns","doi":"10.1111/nyas.15305","DOIUrl":"10.1111/nyas.15305","url":null,"abstract":"The joint position reproduction (JPR) approach is commonly used to assess joint position sense (JPS), but its psychometric properties in children remain unexplored. This study aimed to assess the reliability and precision of a multi-joint JPR protocol for assessing lower-limb JPS in typically developing (TD) children. Ankle, knee, and hip JPS were assessed in TD children (aged 5–12 years), on two different days, by a single rater using a standardized JPR protocol. The mean and best error (joint reproduction error, °) between the target and reproduction angle were calculated from three-dimensional kinematics for each joint across three trials. Total, joint, and limb JRE scores were provided. For JPR reliability, the intraclass correlation coefficient (ICC, 2.1) was reported. For JPR precision, the standard error of measurement (SEM) and smallest detectable difference (SDD) were calculated. Across 270 JPR trials (15 children, 8.6 ± 1.2 years, 8 boys), the mean and best JRE were 3.7° and 2.5°, respectively. The ICC ranged from poor to fair (0.01–0.44) for mean JRE, and fair to very good (0.46–0.77) for best JRE. The SEM ranged from 0.8° to 1.8°. The SDD was less than 5°, ranging from 2.3° to 4.5°. Evaluating ankle, knee, and hip JPS in children using passive JPR is more reliable and precise when using the best JRE. This study highlights the need for a multi-joint JPR approach and provide joint- and limb-specific SEM and SDD values.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"144-156"},"PeriodicalIF":4.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143666689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attention sanctuaries: Social practice guidelines and emergent strategies in attention activism 注意庇护所：注意行动主义的社会实践指南和应急策略

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-20 DOI: 10.1111/nyas.15313

D. Graham Burnett, Eve Mitchell

引用次数: 0

The natural history of social bonds 社会纽带的自然历史

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-18 DOI: 10.1111/nyas.15318

Joan B. Silk

引用次数: 0

Balancing act: The dual role of claudin-2 in disease 平衡作用：claudin‐2在疾病中的双重作用

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-18 DOI: 10.1111/nyas.15311

Shanshan Wu, Jia Gao, Yiran Han, Wenzhe Zhang, Xue Li, Derun Kong, Hua Wang, Li Zuo

{"title":"Balancing act: The dual role of claudin-2 in disease","authors":"Shanshan Wu, Jia Gao, Yiran Han, Wenzhe Zhang, Xue Li, Derun Kong, Hua Wang, Li Zuo","doi":"10.1111/nyas.15311","DOIUrl":"10.1111/nyas.15311","url":null,"abstract":"Claudin-2 (CLDN2), a tight junction protein, is predominantly found in leaky epithelial cell layers where it plays a pivotal role in forming paracellular pores necessary for the efficient transport of cations and water. Its abundance is intricately regulated by upstream signals, modulating its synthesis, transport, and localization to adapt to diverse environmental changes. Aberrant expression levels of CLDN2 are observed in numerous pathological conditions including cancer, inflammation, immune disorders, fibrosis, and kidney and biliary stones. Recent advances have uncovered the mechanisms by which the loss or restoration of CLDN2 affects functions such as epithelial barrier, cell proliferation, renewal, migration, invasion, and tissue regeneration. This exerts a dual-directional influence on the pathogenesis, perpetuation, and progression of diseases, indicating the potential to both accelerate and decelerate the course of disease evolution. Here, we discuss these nuanced bidirectional regulatory effects mediated by CLDN2, and how it may contribute to the progression or regression of disease when it becomes unbalanced.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"75-89"},"PeriodicalIF":4.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143653321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical and behavioral tracking of rhythm in music: Effects of pitch predictability, enjoyment, and expertise 音乐节奏的皮层和行为追踪：音调可预见性、享受和专业知识的影响

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-18 DOI: 10.1111/nyas.15315

Anne Keitel, Claire Pelofi, Xinyi Guan, Emily Watson, Lucy Wight, Sarah Allen, Iris Mencke, Christian Keitel, Johanna Rimmele

{"title":"Cortical and behavioral tracking of rhythm in music: Effects of pitch predictability, enjoyment, and expertise","authors":"Anne Keitel, Claire Pelofi, Xinyi Guan, Emily Watson, Lucy Wight, Sarah Allen, Iris Mencke, Christian Keitel, Johanna Rimmele","doi":"10.1111/nyas.15315","DOIUrl":"10.1111/nyas.15315","url":null,"abstract":"The cortical tracking of stimulus features is a crucial neural requisite of how we process continuous music. We here tested whether cortical tracking of the beat, typically related to rhythm processing, is modulated by pitch predictability and other top-down factors. Participants listened to tonal (high pitch predictability) and atonal (low pitch predictability) music while undergoing electroencephalography. We analyzed their cortical tracking of the acoustic envelope. Cortical envelope tracking was stronger while listening to atonal music, potentially reflecting listeners’ violated pitch expectations and increased attention allocation. Envelope tracking was also stronger with more expertise and enjoyment. Furthermore, we showed cortical tracking of pitch surprisal (using IDyOM), which suggests that listeners’ expectations match those computed by the IDyOM model, with higher surprisal for atonal music. Behaviorally, we measured participants’ ability to finger-tap to the beat of tonal and atonal sequences in two experiments. Finger-tapping performance was better in the tonal condition, indicating a positive effect of pitch predictability on behavioral rhythm processing. Cortical envelope tracking predicted tapping performance for tonal music, as did pitch-surprisal tracking for atonal music, indicating that high and low predictability might impose different processing regimes. Taken together, our results show various ways that top-down factors impact musical rhythm processing.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"120-135"},"PeriodicalIF":4.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143653320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The beautiful adolescent brain: An evolutionary developmental perspective 美丽的青少年大脑：一个进化发展的视角

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-17 DOI: 10.1111/nyas.15314

B. J. Casey, Alexandra O. Cohen, Adriana Galvan

{"title":"The beautiful adolescent brain: An evolutionary developmental perspective","authors":"B. J. Casey, Alexandra O. Cohen, Adriana Galvan","doi":"10.1111/nyas.15314","DOIUrl":"10.1111/nyas.15314","url":null,"abstract":"The adolescent brain has been characterized as a defective car, with no brakes or steering wheel—only an accelerator. This characterization has been used to explain the impulsive and risky behavior of this transient developmental period. But why do adolescents respond to the world the way they do? In this article, we consider adolescent-specific changes in the brain and behavior from a developmental evolutionary viewpoint in how they might be adaptive. We suggest ways in which the adolescent brain has evolved to explore and learn from new and changing environments as the adolescent gains independence from the caregiver and transitions into an adult. We highlight adolescent-specific changes in the brain and behavior in response to emotional and social cues that may facilitate learning to independently secure resources (e.g., food, water, and shelter) and to establish new social bonds beyond the family or pack for their own survival. Specifically, we focus on how rewards, social cues, and threats in the environment influence behavior and may serve an adaptive role for the adolescent.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"58-74"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15314","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143640695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The strength of organ, tissue, and body field effects determines the frequency of all neoplasia 器官、组织和身体场效应的强度决定了所有肿瘤的发生频率

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-17 DOI: 10.1111/nyas.15306

Piet C. de Groen

{"title":"The strength of organ, tissue, and body field effects determines the frequency of all neoplasia","authors":"Piet C. de Groen","doi":"10.1111/nyas.15306","DOIUrl":"10.1111/nyas.15306","url":null,"abstract":"In 1953, Danely Slaughter proposed the concept of field cancerization, or field effect, to explain the development of additional neoplasia of similar type. A recent theory (de Groen, 2022) states that all DNA is exposed to a constant source of damage, resulting in a constant rate of germline and somatic DNA mutations. If the field effect and constant mutation theories are correct and a single somatic mutation causes the transition from non-neoplastic to neoplastic phenotype, then all rates of neoplasia formation can be modeled by exponential equations containing a single variable that determines the chance of phenotype transition. In this perspective, studies from 1953 till 2021 originating from America, Europe, and Asia about head, chest, abdomen, pelvic, and skin neoplasia were reviewed and showed consistent field effects that are modeled by tapering exponential equations containing a single variable defining field effect strength; Pearson and linear correlation coefficients for observed and modeled data range from 0.994 to 1. Thus, existing data are compatible with a constant rate of DNA damage. Organ-specific, tissue-specific, or body-wide mutagenesis conditions determine the rate of neoplasia development and explain the co-occurrence of seemingly unrelated neoplasia at predictable frequencies. Shared risk factors explain increased risk for additional neoplasia in persons with one neoplastic lesion.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"11-22"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15306","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143640696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differentially expressed miRNAs offer new perspective into cave adaptation of Astyanax mexicanus 差异表达的mirna为墨西哥Astyanax mexicanus洞穴适应提供了新的视角

IF 4.1 3区综合性期刊

Annals of the New York Academy of Sciences Pub Date : 2025-03-13 DOI: 10.1111/nyas.15300

Tathagata Biswas, Huzaifa Hassan, Nicolas Rohner

{"title":"Differentially expressed miRNAs offer new perspective into cave adaptation of Astyanax mexicanus","authors":"Tathagata Biswas, Huzaifa Hassan, Nicolas Rohner","doi":"10.1111/nyas.15300","DOIUrl":"10.1111/nyas.15300","url":null,"abstract":"Astyanax mexicanus, a species with both surface-dwelling and multiple cave-dwelling populations, offers a unique opportunity to study repeated adaptation to dark and resource-scarce environments. While previous work has identified large-scale gene expression changes between morphs under even identical laboratory conditions, the regulatory basis of these expression differences remains largely unexplored. In this study, we focus on microRNAs (miRNAs) as key regulators of gene expression. Our analysis identified 683 mature miRNAs, establishing the first comprehensive catalog of miRNAs for this species. We identified a unique subset of differentially expressed miRNAs common to all studied cave-dwelling populations, potentially orchestrating the nuanced gene expression patterns required for survival in the cave milieu. Furthermore, we performed in silico target prediction of these miRNAs, revealing possible roles in developmental and metabolic pathways pivotal for thriving in nutrient-limited cave conditions. Interestingly, we also observed that Molino, which is the “youngest” of the three cavefish analyzed in this study, exhibited the most abundant number of differentially expressed mature miRNAs among the cave morphs. The comprehensive miRNA catalog generated, along with the insight into their differential expression across different morphs, will guide future investigations into the intricate world of miRNA-mediated evolution of complex traits.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"1546 1","pages":"173-181"},"PeriodicalIF":4.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nyas.15300","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143618242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0