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Does Food Engineering Still Need High Pressure? 食品工程还需要高压吗？
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2026-01-30 DOI: 10.1146/annurev-chembioeng-082323-120912
Robert Sevenich, Julia Matysek, Cornelia Rauh
{"title":"Does Food Engineering Still Need High Pressure?","authors":"Robert Sevenich, Julia Matysek, Cornelia Rauh","doi":"10.1146/annurev-chembioeng-082323-120912","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-082323-120912","url":null,"abstract":"<p><p>High-pressure processing (HPP), also known as high hydrostatic pressure (HHP), is essential in contemporary food engineering. This review evaluates its significance through aspects like microbial safety, nutritional and sensory quality, sustainability, market acceptance, economic viability, and technological versatility. By critically examining the current state and potential of HPP, this article highlights that, despite emerging alternatives, food engineering remains strongly reliant on high pressure as an irreplaceable technology due to its unique benefits in ensuring sustainable, high-quality, and safe food products.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146083827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Chemical Engineers in the Pharmaceutical Industry. 化学工程师在制药工业中的作用。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2026-01-21 DOI: 10.1146/annurev-chembioeng-100724-081046
Paul C Collins, Jean W Tom
{"title":"The Role of Chemical Engineers in the Pharmaceutical Industry.","authors":"Paul C Collins, Jean W Tom","doi":"10.1146/annurev-chembioeng-100724-081046","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-081046","url":null,"abstract":"<p><p>Chemical engineers have played a vital role in the pharmaceutical industry for more than a century, bridging the gap between scientific discovery and large-scale drug manufacturing. This review examines the evolution in the role of chemical engineers and their impact on the development of small molecules, biologics, and emerging modalities such as oligonucleotides and gene therapies. We provide historical context, from early breakthroughs in insulin and penicillin production to the integration of continuous processing and advanced modeling. Key areas of focus include reaction engineering, separations, crystallization, fluid dynamics, process control, and continuous manufacturing. Looking ahead, chemical engineers will be central to addressing challenges in sustainability, advanced delivery systems, and the application of artificial intelligence and data-driven technologies. As therapeutic complexity grows, the application of engineering fundamentals, integrated with life and natural sciences, remains essential for ensuring safe, efficient, and scalable manufacturing of medicines that advance global health.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146017257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymer Electrolytes for Rechargeable Sodium Batteries: Review of Characterization of Bulk and Interfacial Properties. 可充电钠电池用聚合物电解质：体积和界面特性的研究进展。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2026-01-20 DOI: 10.1146/annurev-chembioeng-100724-083133
Fati Lukeman, Piyush Deshpande, Jennifer L Schaefer
{"title":"Polymer Electrolytes for Rechargeable Sodium Batteries: Review of Characterization of Bulk and Interfacial Properties.","authors":"Fati Lukeman, Piyush Deshpande, Jennifer L Schaefer","doi":"10.1146/annurev-chembioeng-100724-083133","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-083133","url":null,"abstract":"<p><p>Sodium-based batteries are gaining momentum as a cost-effective, sustainable alternative to lithium-based batteries, driven by the global demand for scalable energy storage. At the same time, polymer electrolytes are being widely pursued as safer, more electrochemically stable alternatives to liquid electrolytes. Sodium polymer electrolytes require advancement in various aspects, such as ion transport and electrode compatibility, before application in rechargeable sodium-ion or sodium metal batteries. This review examines the progress in characterization of the bulk properties of sodium polymer electrolytes, molecular interactions in the bulk, and their interfaces/interphases with electrodes, with attention paid to differences between characterization methodology and select properties of sodium versus lithium analogs. Highlighted topics include ionic conductivity, sodium transference, ion speciation, electrochemical stability, safety, and electrochemical and chemical characterization of interfaces, interphases, and with sodium sulfur cathodes.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Polymer Engineering in Achieving Desirable Properties for Tissue Engineering Applications: Bulk Modification and Bioconjugation of Aliphatic Polyesters. 聚合物工程在组织工程应用中实现理想性能的作用：脂肪族聚酯的体修饰和生物偶联。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2026-01-16 DOI: 10.1146/annurev-chembioeng-100724-081005
Heloísa Bremm Madalosso, Camila Guindani, Pedro Henrique Hermes de Araújo, Claudia Sayer
{"title":"The Role of Polymer Engineering in Achieving Desirable Properties for Tissue Engineering Applications: Bulk Modification and Bioconjugation of Aliphatic Polyesters.","authors":"Heloísa Bremm Madalosso, Camila Guindani, Pedro Henrique Hermes de Araújo, Claudia Sayer","doi":"10.1146/annurev-chembioeng-100724-081005","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-081005","url":null,"abstract":"<p><p>Tissue engineering aims to restore, maintain, or improve damaged tissues through the use of polymer scaffolds that support cellular growth and regeneration. Copolymerization enables the fine-tuning of thermal, structural, and mechanical polymer properties, facilitating scaffold fabrication via techniques like electrospinning and 3D printing. Functionalization and bioconjugation approaches, including thiol-ene click chemistry, allow for targeted surface modification without altering bulk properties, improving interaction with biological environments and enhancing the specificity and functionality of polyester-based scaffolds. This review highlights the central role of polymer reaction engineering in advancing aliphatic polyesters for tissue engineering, focusing on recent innovations in synthetic strategies and functionalization techniques that expand their applicability in regenerative medicine.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are We Chasing After Windmills? Barriers to Carbon Dioxide Utilization. 我们是在追逐风车吗？二氧化碳利用的障碍。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2026-01-13 DOI: 10.1146/annurev-chembioeng-100724-080823
Daniel A Hickman
{"title":"Are We Chasing After Windmills? Barriers to Carbon Dioxide Utilization.","authors":"Daniel A Hickman","doi":"10.1146/annurev-chembioeng-100724-080823","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-080823","url":null,"abstract":"<p><p>The conversion of CO<sub>2</sub> into fuels and chemicals requires significant energy input to break C-O bonds and create C-C and C-H bonds. This review explores the energy and capital barriers to CO<sub>2</sub> utilization, using ethylene production as a case study by comparing CO<sub>2</sub> electroreduction with other carbon mitigation options, including carbon capture and sequestration. The world's energy and capital resources are limited-scarce, in the parlance of economics-and choosing to use them to implement one path to decarbonization displaces other options for decarbonization or other priorities. These opportunity costs are significant and should not be ignored. Instead of breaking the C-O bonds in CO<sub>2</sub> to produce chemicals and fuels, society should prioritize the higher CO<sub>2</sub> mitigation efficiencies of alternative approaches, such as carbon capture and sequestration, new process and catalyst technologies for key molecules, and capital-efficient hydrogen production.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extended Law of Corresponding States: Origins, Challenges, and Applications to Protein Solutions. 相应态扩展定律：起源、挑战和在蛋白质解决方案中的应用。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2025-12-10 DOI: 10.1146/annurev-chembioeng-100724-073401
Néstor E Valadez-Pérez, Florian Platten, Alejandro Gil-Villegas, Ramón Castañeda-Priego
{"title":"Extended Law of Corresponding States: Origins, Challenges, and Applications to Protein Solutions.","authors":"Néstor E Valadez-Pérez, Florian Platten, Alejandro Gil-Villegas, Ramón Castañeda-Priego","doi":"10.1146/annurev-chembioeng-100724-073401","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-073401","url":null,"abstract":"<p><p>The phase diagram of colloidal systems strongly depends on the nature of interparticle interactions, which reflect the physical mechanisms that stabilize the particles in the medium. In systems with dominant short-range attractions, where interactions act over distances much shorter than the particle diameter, the extended law of corresponding states asserts that an interaction potential can be described by three key parameters: effective diameter, interaction strength, and second virial coefficient. If these parameters are the same, then different systems exhibit identical phase behavior, structure, and dynamics. In this review, we outline the origin and formulation of this law and the evidence that supports it. We further examine its applicability to protein solutions near liquid-liquid phase separation and to colloidal systems with short-range attraction and long-range repulsion, exploring the possibility of a universal phase diagram and extending its relevance for understanding the nature of these complex fluids.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145720837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiscale Measurement and Modeling of Methane Emissions in US Oil and Gas Production Regions. 美国油气产区甲烷排放的多尺度测量和建模。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2025-12-10 DOI: 10.1146/annurev-chembioeng-100724-074807
David T Allen, Qining Chen, Arvind P Ravikumar, Erin E Tullos
{"title":"Multiscale Measurement and Modeling of Methane Emissions in US Oil and Gas Production Regions.","authors":"David T Allen, Qining Chen, Arvind P Ravikumar, Erin E Tullos","doi":"10.1146/annurev-chembioeng-100724-074807","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100724-074807","url":null,"abstract":"<p><p>The emergence of the United States as the leading global producer of oil and gas has driven increased interest in the greenhouse gas emissions from US energy supply chains. Methane emissions are a major portion of these greenhouse gas emissions, and the spatial and temporal patterns of methane emissions from oil and gas sources are complex. A wide variety of measurement and modeling approaches for estimating methane emissions from US oil and gas supply chains have emerged over the last decade, and this review summarizes their current status and prospects for improvement. Although no single measurement method or modeling approach will be successful in accurately characterizing all emissions, the integration of multi-scale measurement and modeling approaches can provide accurate and comprehensive estimates of emissions.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145720882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Introduction. 介绍。
IF 7.6 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2025-06-01 DOI: 10.1146/annurev-chembioeng-043025-010930
{"title":"Introduction.","authors":"","doi":"10.1146/annurev-chembioeng-043025-010930","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-043025-010930","url":null,"abstract":"","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"16 1","pages":"i-ii"},"PeriodicalIF":7.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging the Immunological Impacts of Irreversible Electroporation as a New Frontier for Cancer Therapy. 利用不可逆电穿孔的免疫学影响作为癌症治疗的新前沿。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2025-06-01 Epub Date: 2025-02-04 DOI: 10.1146/annurev-chembioeng-082223-054259
Joseph R Vallin, Samira M Azarin
{"title":"Leveraging the Immunological Impacts of Irreversible Electroporation as a New Frontier for Cancer Therapy.","authors":"Joseph R Vallin, Samira M Azarin","doi":"10.1146/annurev-chembioeng-082223-054259","DOIUrl":"10.1146/annurev-chembioeng-082223-054259","url":null,"abstract":"<p><p>Irreversible electroporation (IRE) is a nonthermally mediated tissue ablation modality that makes use of short pulsed electric fields to destroy cancerous lesions in situ. In the past two decades, IRE has established itself not only as an effective means to ablate small, unresectable tumor masses but also as a tool particularly qualified to modulate the tumor microenvironment in a way that dismantles pathways of cancer immunosuppression and permits the development of a systemic antitumor immune response. However, despite its immune-stimulating tendencies, for most cancers conventional IRE alone is insufficient to establish an immune response robust enough to fully eliminate disseminated disease and prevent recurrence. Here, we describe the current understanding of the histological and immunological effects of IRE, as well as recent efforts to optimize IRE parameters and develop rational combination therapies to increase the efficacy of the resulting immune response.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":"169-193"},"PeriodicalIF":12.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selected Chemical Engineering Applications in Nuclear-Waste Processing at the Savannah River Site. 选择化学工程在萨凡纳河核废物处理中的应用。
IF 12.8 2区 工程技术
Annual review of chemical and biomolecular engineering Pub Date : 2025-06-01 Epub Date: 2025-02-27 DOI: 10.1146/annurev-chembioeng-082223-053509
Steven H Crouse, Rupanjali Prasad, Nischal Maharjan, Viviana Cardenas Ocampo, Wesley H Woodham, Dan P Lambert, Ronald W Rousseau, Martha A Grover
{"title":"Selected Chemical Engineering Applications in Nuclear-Waste Processing at the Savannah River Site.","authors":"Steven H Crouse, Rupanjali Prasad, Nischal Maharjan, Viviana Cardenas Ocampo, Wesley H Woodham, Dan P Lambert, Ronald W Rousseau, Martha A Grover","doi":"10.1146/annurev-chembioeng-082223-053509","DOIUrl":"10.1146/annurev-chembioeng-082223-053509","url":null,"abstract":"<p><p>The Savannah River Site has been successfully processing and immobilizing nuclear waste since 1996. However, recent developments in both the scientific understanding of chemical principles and the engineering of immobilizing nuclear-waste systems demand a review of the state of the art. These recent advances have significance to other locations that immobilize nuclear waste. The subject matter of this review may find special applicability to chemical engineers interested in hazardous chemical processes (such as processing toxic and radioactive nuclear waste) and to those in the nuclear industry curious about current research in nuclear-waste processing at a site that has eclipsed the quarter-century mark of large-scale (136 million L total) nuclear-waste processing.</p>","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":"349-370"},"PeriodicalIF":12.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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