Annual review of chemical and biomolecular engineering最新文献_第2页

Organic Mixed Conductors for Neural Biomimicry and Biointerfacing. 用于神经仿生和生物界面的有机混合导体。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2025-01-29 DOI: 10.1146/annurev-chembioeng-082323-114810

Dace Gao, Tom P A van der Pol, Chiara Musumeci, Deyu Tu, Simone Fabiano

引用次数: 0

On-Demand Polymer Materials for Sustainability and Space. 可持续性和空间的按需高分子材料。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2025-01-15 DOI: 10.1146/annurev-chembioeng-082223-101241

Micah S Ziegler, Blair Brettmann

引用次数: 0

Microfluidic and Computational Tools for Neurodegeneration Studies. 神经退行性变研究的微流体和计算工具。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2025-01-15 DOI: 10.1146/annurev-chembioeng-082223-054547

Kin Gomez, Victoria R Yarmey, Hrishikesh Mane, Adriana San-Miguel

{"title":"Microfluidic and Computational Tools for Neurodegeneration Studies.","authors":"Kin Gomez, Victoria R Yarmey, Hrishikesh Mane, Adriana San-Miguel","doi":"10.1146/annurev-chembioeng-082223-054547","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-082223-054547","url":null,"abstract":"Understanding the molecular, cellular, and physiological components of neurodegenerative diseases (NDs) is paramount for developing accurate diagnostics and efficacious therapies. However, the complexity of ND pathology and the limitations associated with conventional analytical methods undermine research. Fortunately, microfluidic technology can facilitate discoveries through improved biomarker quantification, brain organoid culture, and small animal model manipulation. Because this technology can increase experimental throughput and the number of metrics that can be studied in concert, it demands more sophisticated computational tools to process and analyze results. Advanced analytical algorithms and machine learning platforms can address this challenge in data generated from microfluidic systems, but they can also be used outside of devices to discern patterns in genomic, proteomic, anatomical, and cognitive data sets. We discuss these approaches and their potential to expedite research discoveries and improve clinical outcomes through ND characterization, diagnosis, and treatment platforms.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Models for Decarbonization in the Chemical Industry. 化工行业的脱碳模式。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1146/annurev-chembioeng-100522-114115

Yuan Yao, Kai Lan, Thomas E Graedel, Narasimha D Rao

{"title":"Models for Decarbonization in the Chemical Industry.","authors":"Yuan Yao, Kai Lan, Thomas E Graedel, Narasimha D Rao","doi":"10.1146/annurev-chembioeng-100522-114115","DOIUrl":"10.1146/annurev-chembioeng-100522-114115","url":null,"abstract":"Various technologies and strategies have been proposed to decarbonize the chemical industry. Assessing the decarbonization, environmental, and economic implications of these technologies and strategies is critical to identifying pathways to a more sustainable industrial future. This study reviews recent advancements and integration of systems analysis models, including process analysis, material flow analysis, life cycle assessment, techno-economic analysis, and machine learning. These models are categorized based on analytical methods and application scales (i.e., micro-, meso-, and macroscale) for promising decarbonization technologies (e.g., carbon capture, storage, and utilization, biomass feedstock, and electrification) and circular economy strategies. Incorporating forward-looking, data-driven approaches into existing models allows for optimizing complex industrial systems and assessing future impacts. Although advances in industrial ecology-, economic-, and planetary boundary-based modeling support a more holistic systems-level assessment, more efforts are needed to consider impacts on ecosystems. Effective applications of these advanced, integrated models require cross-disciplinary collaborations across chemical engineering, industrial ecology, and economics.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":"139-161"},"PeriodicalIF":7.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Introduction. 介绍。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-07-01 DOI: 10.1146/annurev-ch-15-040824-100001

Michael F Doherty, Rachel A Segalman, Ravi S Kane

引用次数: 0

Reassessing the Standard Chemotaxis Framework for Understanding Biased Migration in Helicobacter pylori. 重新评估理解幽门螺杆菌偏性迁移的标准趋化性框架。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-07-01 Epub Date: 2024-07-03 DOI: 10.1146/annurev-chembioeng-100722-114625

Jyot D Antani, Aakansha Shaji, Rachit Gupta, Pushkar P Lele

{"title":"Reassessing the Standard Chemotaxis Framework for Understanding Biased Migration in Helicobacter pylori.","authors":"Jyot D Antani, Aakansha Shaji, Rachit Gupta, Pushkar P Lele","doi":"10.1146/annurev-chembioeng-100722-114625","DOIUrl":"10.1146/annurev-chembioeng-100722-114625","url":null,"abstract":"Helicobacter pylori infections are a major cause of peptic ulcers and gastric cancers. The development of robust inflammation in response to these flagellated, motile bacteria is correlated with poor prognosis. Chemotaxis plays a crucial role in H. pylori colonization, enabling the bacteria to swim toward favorable chemical environments. Unlike the model species of bacterial chemotaxis, Escherichia coli, H. pylori cells possess polar flagella. They run forward by rotating their flagella counterclockwise, whereas backward runs are achieved by rotating their flagella clockwise. We delve into the implications of certain features of the canonical model of chemotaxis on our understanding of biased migration in polarly flagellated bacteria such as H. pylori. In particular, we predict how the translational displacement of H. pylori cells during a backward run could give rise to chemotaxis errors within the canonical framework. Also, H. pylori lack key chemotaxis enzymes found in E. coli, without which sensitive detection of ligands with a wide dynamic range seems unlikely. Despite these problems, H. pylori exhibit robust ability to migrate toward urea-rich sources. We emphasize various unresolved questions regarding the biophysical mechanisms of chemotaxis in H. pylori, shedding light on potential directions for future research. Understanding the intricacies of biased migration in H. pylori could offer valuable insights into how pathogens breach various protective barriers in the human host.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":" ","pages":"51-62"},"PeriodicalIF":7.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138481848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Will Hydrogen Be a New Natural Gas? Hydrogen Integration in Natural Gas Grids. 氢气会成为新的天然气吗？天然气电网中的氢整合。

IF 7.6 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-07-01 DOI: 10.1146/annurev-chembioeng-100522-110306

Gerald Linke

{"title":"Will Hydrogen Be a New Natural Gas? Hydrogen Integration in Natural Gas Grids.","authors":"Gerald Linke","doi":"10.1146/annurev-chembioeng-100522-110306","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100522-110306","url":null,"abstract":"Hydrogen is similar to natural gas in terms of its physical and chemical properties but does not release carbon dioxide when burnt. This makes hydrogen an energy carrier of great importance in climate policy, especially as an enabler of increasing integration of volatile renewable energy, progressive electrification, and effective emission reductions in the hard-to-decarbonize sectors. Leaving aside the problems of transporting hydrogen as a liquid, technological challenges along the entire supply chain can be considered as solved in principle, as shown in the experimental findings of the Hydrogen Innovation Program of the German Technical and Scientific Association for Gas and Water. By scaling up production and end-use capacities and, most importantly, producing hydrogen in regions with abundant renewable energy, hydrogen and its applications can displace natural gas at affordable prices in the medium term. However, this substitution will take place at different rates in different regions and with different levels of added value, all of which must be understood for hydrogen uptake to be successful.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"15 1","pages":"63-80"},"PeriodicalIF":7.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluid Ejections in Nature 自然界中的流体喷射

IF 8.4 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-04-26 DOI: 10.1146/annurev-chembioeng-100722-113148

Elio J. Challita, Pankaj Rohilla, M. Saad Bhamla

引用次数: 0

Biological Upcycling of Plastics Waste 塑料废弃物的生物升级再造

IF 8.4 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-04-15 DOI: 10.1146/annurev-chembioeng-100522-115850

Ross R. Klauer, D. Alex Hansen, Derek Wu, Lummy Maria Oliveira Monteiro, Kevin V. Solomon, Mark A. Blenner

{"title":"Biological Upcycling of Plastics Waste","authors":"Ross R. Klauer, D. Alex Hansen, Derek Wu, Lummy Maria Oliveira Monteiro, Kevin V. Solomon, Mark A. Blenner","doi":"10.1146/annurev-chembioeng-100522-115850","DOIUrl":"https://doi.org/10.1146/annurev-chembioeng-100522-115850","url":null,"abstract":"Plastic wastes accumulate in the environment, impacting wildlife and human health and representing a significant pool of inexpensive waste carbon that could form feedstock for the sustainable production of commodity chemicals, monomers, and specialty chemicals. Current mechanical recycling technologies are not economically attractive due to the lower-quality plastics that are produced in each iteration. Thus, the development of a plastics economy requires a solution that can deconstruct plastics and generate value from the deconstruction products. Biological systems can provide such value by allowing for the processing of mixed plastics waste streams via enzymatic specificity and using engineered metabolic pathways to produce upcycling targets. We focus on the use of biological systems for waste plastics deconstruction and upcycling. We highlight documented and predicted mechanisms through which plastics are biologically deconstructed and assimilated and provide examples of upcycled products from biological systems. Additionally, we detail current challenges in the field, including the discovery and development of microorganisms and enzymes for deconstructing non–polyethylene terephthalate plastics, the selection of appropriate target molecules to incentivize development of a plastic bioeconomy, and the selection of microbial chassis for the valorization of deconstruction products.","PeriodicalId":8234,"journal":{"name":"Annual review of chemical and biomolecular engineering","volume":"57 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140571712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CRISPR Tools for Engineering Prokaryotic Systems: Recent Advances and New Applications 用于原核系统工程的 CRISPR 工具：最新进展和新应用

IF 8.4 2区工程技术

Annual review of chemical and biomolecular engineering Pub Date : 2024-04-10 DOI: 10.1146/annurev-chembioeng-100522-114706

Diego Alba Burbano, Cholpisit Kiattisewee, Ava V. Karanjia, Ryan A.L. Cardiff, Ian D. Faulkner, Widianti Sugianto, James M. Carothers

引用次数: 0