Melissa S. Ma, Victoria J. Shi, Eric Koza, Misha Haq, Areeba Ahmed, Kelly A. Reynolds, Emily Poon, Murad Alam
{"title":"Correctly classifying cohort studies versus case series in systematic reviews and implications for evidence-based decision making","authors":"Melissa S. Ma, Victoria J. Shi, Eric Koza, Misha Haq, Areeba Ahmed, Kelly A. Reynolds, Emily Poon, Murad Alam","doi":"10.1007/s00403-024-03458-3","DOIUrl":"10.1007/s00403-024-03458-3","url":null,"abstract":"<div><p>The strength of a systematic review hinges in large part on the quality of evidence it appraises. Observational studies, including cohort studies and case series, are positioned lower on the hierarchy of evidence, with cohort studies typically higher than case series. The often subtle differences between these study designs may lead to misclassification and can impact the strength of recommendations derived from such data. This manuscript offers an approach to delineate the differences between cohort studies and case series and provides clinical examples of these subtleties. By providing a simple approach for distinguishing cohort studies from case series, this manuscript seeks to assist researchers performing systematic reviews.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ambika Nohria, Deesha Desai, Derek Maas, Mackenzie R. Martin, Zasca-aisha Ristianto, Fatima Bawany, Jerry Shapiro, Daniel R. Mazori, Kristen I. Lo Sicco
{"title":"Impact of an alopecia educational lecture on medical student knowledge","authors":"Ambika Nohria, Deesha Desai, Derek Maas, Mackenzie R. Martin, Zasca-aisha Ristianto, Fatima Bawany, Jerry Shapiro, Daniel R. Mazori, Kristen I. Lo Sicco","doi":"10.1007/s00403-024-03499-8","DOIUrl":"10.1007/s00403-024-03499-8","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting the Role of Antistreptococcal Therapy in Psoriasis: Insights and Evidence","authors":"Pearl Dogra, Jaideep Dogra","doi":"10.1007/s00403-024-03440-z","DOIUrl":"10.1007/s00403-024-03440-z","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angela Bonjorno Arantes, Rosimeire Takaki Rosa, Nicoly Subtil de Oliveira, Luiz Fernando Bianchini, Rodrigo Nunes Rached, Aline Cristina Batista Rodrigues Johann, Saulo Henrique Weber, Fábio Seigi Murakami, Daniela Florencio Maluf, Edvaldo Antonio Ribeiro Rosa
{"title":"Facial disbiosis and UV filters","authors":"Angela Bonjorno Arantes, Rosimeire Takaki Rosa, Nicoly Subtil de Oliveira, Luiz Fernando Bianchini, Rodrigo Nunes Rached, Aline Cristina Batista Rodrigues Johann, Saulo Henrique Weber, Fábio Seigi Murakami, Daniela Florencio Maluf, Edvaldo Antonio Ribeiro Rosa","doi":"10.1007/s00403-024-03501-3","DOIUrl":"10.1007/s00403-024-03501-3","url":null,"abstract":"<div><p>Acne is a multifactorial inflammatory disease with a robust microbial component and numerous correlations with dysbiosis states. Furthermore, various factors are recognized as triggers for skin dysbiosis, including the use of certain cosmetics. Based on these arguments, we hypothesized that using photoprotective formulations could trigger dysbiosis and the occurrence of acne manifestations. To verify this assumption, six volunteers between 19 and 23 years of age, meeting all the inclusion criteria, received two applications a day of a non-commercial sunscreen formulation developed with the sun filters ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene dispersed in a base gel, with an estimated protection factor of 28.8. The pure base gel was used as a control. The samples were applied to an area delimited by a standard template (15 cm<sup>2</sup>) in an amount corresponding to 30 mg (2 mg cm<sup>2</sup>) for ten days. At two points in time, pre- and post-sample applications, the facial skin surface was swabbed to collect extracted DNA and processed to verify divergent degrees of 16 S RNA coding sequences. The data obtained allowed us to determine the abundance of different bacterial entities at the genus and species levels. The results showed that critical species of the acne process, such as <i>Cutibacterium</i> acnes and <i>Staphylococcus epidermidis</i>, seem to tolerate the evaluated formulation well and are not significantly affected by the formulation, suggesting no interference of its use concerning dysbiosis induction. These findings refute the idea that photoprotectors may cause skin dysbiosis in men.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and safety of risankizumab in Turkish adults with chronic plaque psoriasis: a one year single-center, retrospective, real-life study","authors":"Gulsen Akoglu, Zeyneb Tecik","doi":"10.1007/s00403-024-03500-4","DOIUrl":"10.1007/s00403-024-03500-4","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Supawadee Sukseree, Noreen Karim, Ionela Mariana Nagelreiter, Robert H. Rice, Leopold Eckhart
{"title":"Identification of autophagy-regulated proteins by proteomic analysis of tape-stripped stratum corneum","authors":"Supawadee Sukseree, Noreen Karim, Ionela Mariana Nagelreiter, Robert H. Rice, Leopold Eckhart","doi":"10.1007/s00403-024-03491-2","DOIUrl":"10.1007/s00403-024-03491-2","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ibrahim ElGhareeb, Sahar ElMokadem, Marwa Elsherif, Kamal ElKashishy
{"title":"Interleukin 9 in Oral Lichen Planus: an immunohistochemical study before and after treatment by intralesional steroid injection","authors":"Mohamed Ibrahim ElGhareeb, Sahar ElMokadem, Marwa Elsherif, Kamal ElKashishy","doi":"10.1007/s00403-024-03452-9","DOIUrl":"10.1007/s00403-024-03452-9","url":null,"abstract":"<div><p>Oral Lichen Planus (OLP) is a chronic inflammatory mucocutaneous disorder of the oral mucosa. Th9 cells secrete IL9, which induces elevated levels of MMP9, exacerbating OLP disease severity. IL9 also increases Th17 levels in OLP lesions. This study aimed to detect IL9 tissue expression in patients with OLP compared to normal controls and to correlate its expression with disease severity and response to intralesional steroid therapy. This study involved 18 patients with OLP and 18 healthy, age- and sex-matched volunteers. The REU scoring system was used to monitor OLP lesions before and after treatment with 20 mg/mL intralesional triamcinolone acetonide every 2 weeks for four sessions. Biopsies for H&E and IL-9 expression were taken from patients and controls, with repeat biopsies after the fourth session for patients. A highly statistically significant increase in IL9 expression was observed in the patient group compared with the control group. A highly statistically significant decrease in both the REU score and post-treatment IL-9 expression was detected in the patient group. We can conclude that IL9 is a tissue marker of OLP activity. Future studies on therapies targeting IL-9 in OLP are needed.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142581377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandesh Raja, Adarsh Raja, Muhammad Hamza Shuja, Azzam Ali
{"title":"Clinical benefits of delgocitinib cream for chronic hand eczema: a systematic review and meta-analysis","authors":"Sandesh Raja, Adarsh Raja, Muhammad Hamza Shuja, Azzam Ali","doi":"10.1007/s00403-024-03502-2","DOIUrl":"10.1007/s00403-024-03502-2","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142562586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trace elements in psoriasis presentation and treatment","authors":"Pratiksha Patra, Tyler Harrison","doi":"10.1007/s00403-024-03468-1","DOIUrl":"10.1007/s00403-024-03468-1","url":null,"abstract":"<div><p>This systematic literature review examines the relationship between psoriasis and trace metals to elucidate the pathogenesis of this condition, and to explore their potential use as a new route of treatment. Searches were primarily conducted in three databases: PubMed, Scopus, and Embase. The initial search resulted in over 100 articles which were manually assessed by the researchers to determine relevancy. Articles were only included if they were published within the last 12 years and were held to the standards of Boote and Biele’s Literature Review Rubric to assess their quality. Of the relevant articles included in this study, the following three elements were largely discussed: calcium, magnesium, and zinc. Although not a trace metal, the macromolecule, calcium, was found to regulate the differentiation and proliferation of cells involved in the pathogenesis of psoriasis. Magnesium is thought to have an indirect relationship with psoriasis due to its role in Vitamin D absorption. Additionally, the zinc ion protects against oxidative stress, which is theorized as a mediator of the inflammatory response central to the pathogenesis of psoriasis. Many studies also investigated the serum levels of these elements to see if they were correlated with the severity of the condition. The serum levels of both calcium and zinc were found to have a negative correlation with the amount of surface area involved during a plaque psoriasis flare. These results indicate a potential benefit from evaluating the serum levels of these key modulators in patients. The lab values would indicate any deficiencies or imbalances, which can assist in a physician’s ability to determine an individualized and targeted treatment course. Findings from this review consolidate the information currently available, and support the idea that psoriasis is influenced by trace metals. While there is still limited discussion on the evaluation of this relationship, the reviews findings demonstrate that additional comprehensive research would be warranted.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"316 10","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142562596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}