Christopher A. Guirguis, Lauren M. Ching, Laura K. Ferris
{"title":"Biologics and skin cancer risk in psoriasis patients","authors":"Christopher A. Guirguis, Lauren M. Ching, Laura K. Ferris","doi":"10.1007/s00403-024-03706-6","DOIUrl":"10.1007/s00403-024-03706-6","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research advances in the promotion of diabetic wound healing by Baicalin","authors":"Siping Xu, Wenhua Zhang, Xuanfen Zhang","doi":"10.1007/s00403-025-03850-7","DOIUrl":"10.1007/s00403-025-03850-7","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sjögren’s syndrome and psoriasis: a two-sample Mendelian randomization study","authors":"Bingqing Dai, Yu Xin, Wang Jun","doi":"10.1007/s00403-025-03836-5","DOIUrl":"10.1007/s00403-025-03836-5","url":null,"abstract":"<div><p>Primary Sjögren’s Syndrome (PSS) and psoriasis are frequently observed to co-occur in clinical settings. However, the causal associations and underlying mechanisms between PSS and psoriasis remain poorly defined. In this study, we conducted bidirectional MR analysis to explore the causal relationship between PSS and psoriasis using four MR methods: inversevariance weighted, MR-Egger regression, weighted median, and weighted mode. Sensitivity analyses were carried out, employing different models and testing methods for comparison to assess the influence of heterogeneity and pleiotropy on our findings and to confirm the robustness of these results. We primarily employed the Inverse Variance Weighting (IVW) method for our analysis. A p-value of less than 0.05 indicates a significant causal relationship, while a p-value greater than 0.05 suggests the absence of such a relationship. The IVW analysis confirmed a causal relationship between psoriasis and primary Sjögren’s syndrome (PSS) (OR: 3.149E-10, 95% CI 1.114E-18-0.089, P = 0.028), with the weighted median yielding similar results. Conversely, there was no causal association found between PSS and the risk of developing psoriasis (OR: 1.000, 95% CI 0.999–1.000, P = 0.328). This study reveals a causal relationship between primary Sjögren’s syndrome (PSS) and psoriasis, demonstrating that psoriasis increases the risk of developing PSS, while the reverse is not true. This potential causal link offers new insights into the etiology of both PSS and psoriasis.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00403-025-03836-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empowering tattooists in melanoma screening: campaigns, education, and the need for further evaluation","authors":"Nicolas Kluger, Christa De Cuyper","doi":"10.1007/s00403-025-03852-5","DOIUrl":"10.1007/s00403-025-03852-5","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue Cao, Wentao Zhang, Zhongyuan Jia, Shaohong Ma, Lixia Liu
{"title":"Stable vitiligo treated by transplantation of autologous melanocytes: a meta-analysis","authors":"Xue Cao, Wentao Zhang, Zhongyuan Jia, Shaohong Ma, Lixia Liu","doi":"10.1007/s00403-025-03846-3","DOIUrl":"10.1007/s00403-025-03846-3","url":null,"abstract":"<div><h3>Objective</h3><p>To systematically evaluate the efficacy of culture and nonculture autologous melanocyte transplantation and other methods for stable vitiligo.</p><h3>Methods</h3><p>PubMed, Embase, WebofScience, TheCochraneLibrary, Chinese Journal Full-text Database (CNKI), VIP Chinese Scientific Journal Full-text Database (VIP), Wanfang database, were included in the clinical study of autologous cell transplantation for the treatment of stable vitiligo. For the meta-analysis of the corresponding studies with Revman5.3 software.</p><h3>Results</h3><p>17 high-quality studies were included in this meta-analysis, totaling 1199 patients, Meta-analysis showed that there was no significant difference in the efficacy of autologous cultured melanocytes transplantation (CMT) and melanocytes + keratinocytes, CMT and autologous nonculture suspension transplantation (NCES) in stable vitiligo (P > 0.05); There was a significant difference between CMT and CMT + phototherapy in stable vitiligo (P < 0.00001); There was no significant difference in the efficacy of NCES and NCES + other components, NCES and NCES + other therapies, and NCES and NCES + phototherapy for stable vitiligo (P > 0.05); There was a significant difference in the efficacy of cell transplantation and cell transplantation and cell transplantation + other therapy, cell transplantation and cell transplantation + phototherapy,cell transplantation and cell transplantation + narrow spectrum ultraviolet (NBUVB) in stable vitiligo (P < 0.00001).</p><h3>Conclusion</h3><p>Both NCES and CMT transplantation treated stable vitiligo and had no direct relationship with the components contained in the suspension. Melanocyte transplantation and melanocyte transplantation combined with other treatment methods is better than single melanocyte transplantation for vitiligo. Due to the number and quality of included studies, the above conclusions need to be confirmed by more reasonably designed randomized controlled clinical studies.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on “Is vitamin D deficiency a more frequent finding in hirsutism or not?”","authors":"Anna Vittoria Mattioli","doi":"10.1007/s00403-025-03832-9","DOIUrl":"10.1007/s00403-025-03832-9","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evelyn F. Fagan, Christopher Reagen, Bianca Ituarte, Joseph T. McGrath, Sarah Lonowski, Erin X. Wei
{"title":"Sleep disturbances in psoriasis, an analysis of biometric data from the all of us database","authors":"Evelyn F. Fagan, Christopher Reagen, Bianca Ituarte, Joseph T. McGrath, Sarah Lonowski, Erin X. Wei","doi":"10.1007/s00403-024-03699-2","DOIUrl":"10.1007/s00403-024-03699-2","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Demographic and clinicopathological features of cutaneous vasculitis","authors":"Milad Gandomi-Mohammadabadi, Alireza Gandomi-Mohammadabadi, Maryam Nasimi, Ifa Etesami, Hamidreza Mahmoudi, Zeinab Aryanian, Parvaneh Hatami","doi":"10.1007/s00403-025-03835-6","DOIUrl":"10.1007/s00403-025-03835-6","url":null,"abstract":"<div><h3>Background & objective</h3><p>Cutaneous vasculitis has different clinical manifestations. It may be idiopathic or associated with infections, medications, etc.Skin is involved in both small vessel vasculitis (SVV) and medium vascular vasculitis.We aimed to evaluate clinical signs, laboratory and pathological changes of cutaneous vasculitis among Iranian people.</p><h3>Material & methods</h3><p>This study was a descriptive study performed on 74 patients with cutaneous vasculitis from March 2011 to February 2019. Information includes histopathological data, as well as clinical variables including the age of onset, sex, area of involvement, type of lesion, symptoms, and diagnosis. Pathological and laboratory changes were collected and recorded as well.</p><h3>Results</h3><p>Of the 74 patients studied, hypersensitivity vasculitis 52(70%) was the most common form.Most of the patients had lower extremities involvement. The most common clinical features and symptoms were petechiae or purpura and itching. Fever, limb edema, and arthralgia were the most common symptoms, occurring in 26%, 20%, and 18% of patients, respectively. Among patients, 18 (24%) had taken medication before the lesions, 10 (13%) had vasculitis due to infection, and 44 (59%) were diagnosed as idiopathic form. The most common treatment was prednisolone in 69 patients (93%) with a mean dose of 15.6 ± 35 mg.</p><h3>Conclusion</h3><p>The study would be useful in understanding the various specific and non specific features of cutaneous vasculitis, helping the clinician to manage the condition.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neha Arora, Ashley Wittmer, Mojahed Mohammad K. Shalabi, Frank Jing, Umer Nadir, Benjamin F. Kelley, Stanislav N. Tolkachjov
{"title":"Surgical outcomes of Adenoid cystic carcinoma treated with Mohs Micrographic Surgery and excision: a systematic review","authors":"Neha Arora, Ashley Wittmer, Mojahed Mohammad K. Shalabi, Frank Jing, Umer Nadir, Benjamin F. Kelley, Stanislav N. Tolkachjov","doi":"10.1007/s00403-025-03842-7","DOIUrl":"10.1007/s00403-025-03842-7","url":null,"abstract":"<div><p>Adenoid cystic carcinoma (ACC) is a rare cancer that most commonly occurs in the salivary glands, making up approximately 2–4% of all head and neck malignancies. Treatment for ACC varies, with combinations of surgical excision, adjuvant radiotherapy, and chemotherapy reported in the literature. In this study, we aim to assess ACC recurrence rates with Mohs Micrographic Surgery (MMS) treatment compared to traditional wide local excision (WLE). In June of 2024, a comprehensive review of the literature was performed using the following keywords: “Adenoid Cystic Carcinoma” and/or “Mohs Micrographic Surgery” and/or “MMS” and/or “excision.” Between the two databases, 25 articles were identified which included a total of 30 patients. Among all the articles, 30 procedures were documented — 8 MMS and 22 WLE. Patients with ACC treated with WLE had a higher rate of recurrence (40.9%) compared to those treated with MMS (12.5%). Limitations include a small number of tumors treated and reporting bias. MMS for the treatment of ACC demonstrated a decreased recurrence rate compared to WLE. Further studies with larger sample sizes are needed to confirm the benefit of MMS over WLE.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}