Archives of Dermatological Research最新文献

{"title":"Association of inflammatory bowel disease with hidradenitis suppurativa: a global TriNetX database study","authors":"Hannah Verma, Omar Alani, Benjamin D. Hu, Dev Patel, Raphaella Lambert, Grace Rabinowitz, Benjamin Gerstein, Mahaa Ayub, Ahuva Cices, Nicholas Gulati, Jonas A. Adalsteinsson","doi":"10.1007/s00403-025-04360-2","DOIUrl":"10.1007/s00403-025-04360-2","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and validity of Pemphigus Oral Lesions Intensity Score (POLIS) in pemphigus vulgaris","authors":"Maryam Daneshpazhooh,&nbsp;Fatemeh Lotfi,&nbsp;Soodeh Yazdinezhad,&nbsp;Pedram Nourmohammadpour,&nbsp;Kamran Balighi,&nbsp;Amirhoushang Ehsani,&nbsp;Hamidreza Mahmoudi,&nbsp;Ala Ehsani,&nbsp;Amirhossein Rahimnia","doi":"10.1007/s00403-025-04361-1","DOIUrl":"10.1007/s00403-025-04361-1","url":null,"abstract":"<div>\u0000 \u0000 <p>Oral involvement in pemphigus vulgaris (PV) may present as the first or sole symptom. The absence of a reliable oral-specific scoring system complicates disease assessment, monitoring, and clinical trials. This study aimed to evaluate the reliability and validity of the Pemphigus Oral Lesions Intensity Score (POLIS) in comparison with the oral section of Pemphigus Disease Area Index (PDAI-oral), alongside completion time and variable correlations. A cross-sectional study was conducted in the clinic of a referral dermatology hospital. Sixty-eight confirmed oral PV patients (female-male ratio, 1.5:1) with an age of 47.29 ± 11.62 and a disease duration of 5.15 ± 4.08 years were enrolled. Two expert dermatologists examined each patient separately and documented the score and completion time of PDAI-oral and POLIS. A follow-up session was conducted for repeated assessment, in which 14 patients participated. Excellent inter-rater reliability was observed for both PDAI-oral (ICC = 0.958) and POLIS (ICC = 0.928). The strong and statistically significant Pearson correlation between these two scoring systems (<i>r</i> = 0.724, p-value &lt; 0.001 for dermatologist No. 1 and <i>r</i> = 0.746, p-value &lt; 0.001 for dermatologist No. 2) demonstrated POLIS validation in our study. However, the required time for completing POLIS was significantly more than PDAI. POLIS may serve as a comprehensive method for assessing oral PV, addressing both clinical severity and patient-reported aspects of the disease.</p>\u0000 </div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144927013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of 308 nm excimer light in combination with either topical Tazarotene gel 0.1% or topical betamethasone valerate ointment 0.1% in treatment of plaque psoriasis: a clinical and dermoscopic study","authors":"Doaa S. Sayed,&nbsp;Aliaa Effat,&nbsp;Heba Hassan,&nbsp;Eman Fathy","doi":"10.1007/s00403-025-04359-9","DOIUrl":"10.1007/s00403-025-04359-9","url":null,"abstract":"<div>\u0000 \u0000 <p>The excimer light at 308 nm is a common tool in dermatology for a variety of conditions. It works well for hard-to-treat psoriasis subtypes. Using topical corticosteroids is the cornerstone of treating psoriasis. The only topical retinoid that is currently prescribed to treat psoriasis is tazarotene; it lowers inflammation, epidermal hyperproliferation, and aberrant keratinocyte differentiation. Objectives were to assess the safety and effectiveness of 308 nm excimer light monotherapy versus its combination with either topical tazarotene gel 0.1% or betamethasone valerate ointment 0.1% for treatment of localized chronic plaque psoriasis. Thirty psoriasis vulgaris patients (a total of 90 lesions) were divided into 3 groups; group 1: received excimer light alone, group 2: received excimer light with topical tazarotene gel 0.1%, and group 3: received excimer light with topical betamethasone valerate ointment 0.1% for 12 weeks. Assessment was done by photographs, psoriasis severity (TES) score and dermoscopy. A markedly significant improvement in the baseline TES scores after 6 and 12 weeks of treatment was detected in all studied groups. Group 2 achieved a significant improvement after 6 weeks compared to the other 2 groups (<i>p</i> = 0.016). However, after 12 weeks of treatment, groups 2 and 3 achieved significant improvement in their TES scores compared to group 1 but with no significant difference in between (<i>p</i> = 0.229). We concluded that Excimer light combined with topical Tazarotene gel is an efficient and safe line of treatment for psoriasis. It works more effectively than either excimer light monotherapy or excimer light plus topical betamethasone valerate ointment.</p>\u0000 </div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144926926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of polynucleotide, fractional CO2 laser, and their combination in treating striae distensae: a randomized intraindividual clinical trial","authors":"Wilai Thanasarnaksorn,&nbsp;Manida Sintopachakul,&nbsp;Atchima Suwanachinda,&nbsp;Punyaphat Sirithanabadeekul","doi":"10.1007/s00403-025-04348-y","DOIUrl":"10.1007/s00403-025-04348-y","url":null,"abstract":"<div><p>Striae distensae (SD), or stretch marks, are common atrophic dermal scars that can significantly impact psychological well-being. Despite various treatment options, effective management remains challenging. Fractional CO₂ laser (FrCO₂) therapy is widely used for its ability to stimulate collagen and elastin remodeling but carries a risk of post-inflammatory hyperpigmentation (PIH). Polynucleotides (PN), with larger molecular structures and higher concentrations than polydeoxyribonucleotide (PDRN), improve fibroblast viability and enhance collagen synthesis, both of which are essential for tissue repair and regeneration. This study aimed to evaluate the efficacy and safety of PN injections compared with FrCO₂ laser monotherapy and their combination in the treatment of SD. In a 20-week prospective, randomized, intraindividual clinical trial, twenty volunteers with SD persisting for over 12 months were enrolled. Each abdominal lesion was divided into three treatment zones: PN monotherapy, FrCO₂ laser monotherapy, and a combination of both. Outcomes were assessed using digital photography, Antera 3D imaging, and histological evaluations at baseline and weeks 4, 8, 12, and 20. Nineteen patients completed the trial which mean age was 42.45 ± 11.94 years. After a 20-week period, three treatment groups—polynucleotide injections, fractional CO2 laser, and their combination—showed significant improvement in the volume and width of striae (<i>P</i> &lt; 0.001, mean vol change; -0.73, -0.67. -0.77, mean width change; -0.18, -0.18, -0.2 respectively). No statistically significant differences were found between groups regarding striae volume and width reduction; however, the combination therapy showed the highest mean reduction in improving both the volume and width of striae. Polynucleotide treatment was most effective in improving roughness and the Manchester scar scale of striae and exhibited fewer adverse effects compared to FrCO2 laser and combined therapy. Melanin levels increased in the laser and combined treatment groups but remained unchanged in the Polynucleotide group. In conclusion, PN injections are a safe and effective option for treating SD, with comparable efficacy to FrCO₂ laser and fewer side effects. The combination of PN and laser may offer enhanced outcomes through potential synergistic mechanisms however it still carries a high risk of PIH associated with FrCO₂. Further studies are needed to evaluate long-term efficacy and safety.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imiquimod-induced psoriasis-like inflammation model in calcium-differentiated human keratinocytes mimics psoriasis-associated biomolecules and signaling pathways","authors":"Mustafa Cakir,&nbsp;Seda Keskin,&nbsp;Yigit Uyanikgil,&nbsp;Serife Cakir,&nbsp;Eda Acikgoz","doi":"10.1007/s00403-025-04336-2","DOIUrl":"10.1007/s00403-025-04336-2","url":null,"abstract":"<div><p>Dysregulation of keratinocytes and immune response are remarkable phenomena that trigger inflammation in the psoriasis pathology. In vitro models for elucidating psoriasis pathogenesis and treatment provide the potential to mimic enhanced systems that more accurately represent the disease phenotype and immunopathogenesis. The aim of this study was to investigate the morphological, molecular and biochemical changes of cell–cell interactions in CaCl₂-differentiated HaCaT cells under imiquimod (IMQ)-induced inflammatory conditions. To establish this model, HaCaT cells were differentiated with CaCl₂ and then stimulated with IMQ to induce psoriatic inflammation. Morphological analyses were evaluated on inverted microscope images and HE-stained cells under light microscopy. Cell proliferation was analyzed by the MTT assay and confirmed with the PCNA biomarker. Psoriasis-associated biomarkers were evaluated by immunofluorescence staining. Cytokine levels were measured by ELISA, and the expressions of Toll-like receptors (TLRs), NLRP3 inflammasome, angiogenic, hypoxia, and TGF-β/Smads genes were assessed by qRT-PCR. The results revealed that IMQ-induced HaCaT cells exhibited morphology and organization mimicking psoriatic keratinocytes. The expressions of CK17, PCNA, actin, prohibitin and inflammatory cytokines were significantly increased in the IMQ group. Furthermore, significant changes were detected in the gene expression levels of inflammation-related TLRs, NLRP3 inflammasome complex, angiogenic, hypoxia, and TGF-β/Smads. This model effectively mimics psoriatic inflammatory responses in HaCaT cells and may serve as a cost-effective tool to evaluate the anti-psoriatic potential of new drug candidates.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Academic Dermatologist Research Productivity Including Career Age Adjustments and Institutional Comparisons","authors":"Brailyn Weber,&nbsp;Abel Woldu,&nbsp;Nawang Singhe,&nbsp;Maritza V. Steele,&nbsp;Milki Gemeda,&nbsp;Sara Hylwa,&nbsp;Christopher L. Deufel","doi":"10.1007/s00403-025-04356-y","DOIUrl":"10.1007/s00403-025-04356-y","url":null,"abstract":"<div><p>The research productivity of academic dermatology faculty and institutions is frequently assessed by quantitative bibliometrics, for which there are few established benchmarks. The objective of this study was to quantify bibliometrics for dermatology faculty from high-performing academic institutions, measure productivity changes throughout a career, and analyze productivity changes over time. The authors obtained peer-reviewed articles from 1973 to 2023 using Scopus for 410 faculty dermatologists from the 10 highest-ranked United States institutions as determined by Doximity in 2023. This data was used to generate cumulative distribution functions for various bibliometric performance metrics as a function of both career age and among academic institutions. These metrics included authorships (<span>(:dot{A})</span>), first or last authorships (<span>(:dot{FL})</span>), monograph equivalents (<span>(:dot{ME})</span>), h-index, and ha-index. The authors additionally explored bibliometric inflation from the period of 1991 to 2023. Publication rates increased substantially over the course of a dermatologist’s career and peaked after 15–25 years for <span>(:dot{FL})</span> and <span>(:dot{ME})</span>. Median bibliometrics at career ages (1, 10, 20, 30) were <span>(:dot{A})</span>=(1.0, 1.7, 3.4, 3.4) year^− 1, <span>(:dot{FL})</span>=(0.4, 0.6, 1.1, 0.6) year^− 1, <span>(:dot{ME})</span>=(0.3, 0.4, 0.6, 0.4) year^− 1, h-index=(0, 6, 16, 26), and ha-index=(0.5, 3.4, 7.9, 12.6). Between 1991 and 2023, the median number of authors per paper doubled and <span>(:dot{A})</span> increased by 36%, while <span>(:dot{FL})</span> and <span>(:dot{ME})</span> were stable. Inter-institutional performance was comparable, including distributions of lower and higher-performing faculty. In conclusion, intercomparison of academic dermatologist bibliometric performance requires adjustments for career age and era. In the presented work, the authors provide tabulated data for percentile ranking of faculty. Research productivity, measured by <span>(:dot{FL})</span> and <span>(:dot{ME})</span>, has not changed in over 30 years. Lastly, highly ranked institutions have similar distributions of lower and higher performers.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: A 16-week split-face randomized placebo controlled study on the utility of adding intradermal platelet rich plasma to 2% hydroquinone cream in the treatment of melasma","authors":"Neelam Chhajed,&nbsp;Saurabh Singh,&nbsp;Anupama Bains,&nbsp;Abhishek Bhardwaj,&nbsp;Anil Budania,&nbsp;Utkrist Lahoria,&nbsp;Maninder Kaur,&nbsp;Richa Mishra,&nbsp;Saptarshi Mandal","doi":"10.1007/s00403-025-04350-4","DOIUrl":"10.1007/s00403-025-04350-4","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy and safety of clindamycin phosphate/benzoyl peroxide versus adapalene/benzoyl peroxide in acne treatment: a systematic review and meta-analysis","authors":"Song Zhang,&nbsp;Ibrahim Serag,&nbsp;Tangatarova Sofia,&nbsp;Sama Mahmoud Gamal,&nbsp;Mahmoud G. A. Saleh,&nbsp;E. A. Shaban,&nbsp;Mostafa Hossam El Din Moawad","doi":"10.1007/s00403-025-04353-1","DOIUrl":"10.1007/s00403-025-04353-1","url":null,"abstract":"<div>\u0000 \u0000 <p>Acne vulgaris is a common dermatological disorder, primarily affecting adolescents and young adults, often leading to both physical and psychological distress. Combination therapies such as Clindamycin phosphate/Benzoyl Peroxide (CLIN/BPO) and Adapalene/Benzoyl Peroxide (ADAP/BPO) are widely used for treatment; however, direct comparative analyses of their efficacy and safety remain limited. This systematic review and meta-analysis aimed to compare the efficacy and safety profiles of CLIN/BPO versus ADAP/BPO in the treatment of acne vulgaris. A systematic literature search was conducted following PRISMA guidelines across PubMed, Scopus, Web of Science, and Cochrane Library databases. Randomized controlled trials (RCTs) comparing CLIN/BPO with ADAP/BPO were included. Data on treatment-emergent adverse events (TEAEs), treatment discontinuation due to TEAEs, AS reactions, and total lesion count were extracted and analyzed using RevMan 5.3 with a fixed effects model. Three RCTs from the USA and Argentina, including 556 participants, were analyzed. The risk of bias assessment classified two studies as low-risk and one with some concerns. The meta-analysis demonstrated that CLIN/BPO significantly reduced the risk of TEAEs compared to ADAP/BPO (OR = 0.32; 95% CI: 0.21–0.47; <i>p</i> &lt; 0.0001). Additionally, treatment discontinuation due to TEAEs was lower with CLIN/BPO (OR = 0.10; 95% CI: 0.02–0.55; <i>p</i> = 0.008). CLIN/BPO was associated with fewer application site (AS) side effects (OR = 0.40; 95% CI: 0.28–0.55; <i>p</i> &lt; 0.00001), particularly in terms of reduced pain, dryness, and irritation. However, no significant differences were observed in AS exfoliation, dermatitis, erythema, or pruritus. Both treatments showed comparable efficacy in reducing total lesion count (MD = 2.55; 95% CI: -4.11 to 9.22; <i>p</i> = 0.45). CLIN/BPO exhibits a superior safety and tolerability profile compared to ADAP/BPO, with significantly lower rates of TEAEs and AS reactions, while maintaining equivalent efficacy in lesion reduction. These findings suggest that CLIN/BPO may be the preferred option for patients prioritizing safety without compromising treatment effectiveness.</p>\u0000 </div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of ischemia-modified albumin levels and thiol/disulfide balance in patients with acne vulgaris","authors":"Esranur Ünal,&nbsp;Göknur Kalkan,&nbsp;Salim Neşelioğlu,&nbsp;Sinem Örnek Özdemir","doi":"10.1007/s00403-025-04351-3","DOIUrl":"10.1007/s00403-025-04351-3","url":null,"abstract":"<div><p>Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit. The role of oxidative stress in AV remains controversial, with inconsistent findings in previous studies. This study aimed to investigate the relationship between AV and oxidative stress by assessing thiol/disulfide homeostasis parameters and ischemia-modified albumin (IMA) levels as oxidative stress biomarkers. Seventy-five AV patients and 75 age- and sex-matched healthy controls were included in the study. Peripheral blood samples were analyzed for IMA, native thiol (NT), total thiol (TT), NT/TT, disulfide, disulfide/NT, and disulfide/TT. Disease severity was evaluated using the global acne grading system (GAGS), and group comparisons were performed. IMA levels were significantly higher in AV patients than in controls (0.85 ± 0.14 vs. 0.79 ± 0.18, <i>p</i> &lt; 0.05). NT and TT levels were lower in the AV group (317.6 vs. 421.7, <i>p</i> &lt; 0.001; 347.2 vs. 473, <i>p</i> &lt; 0.001), while disulfide/NT and disulfide/TT ratios were higher (5.97 vs. 4.52, <i>p</i> &lt; 0.001; 5.33 vs. 4.15, <i>p</i> &lt; 0.001). No significant differences were observed in disulfide levels (<i>p</i> &gt; 0.05). IMA levels were significantly higher in mild cases compared to moderate cases (0.89 ± 0.2 vs. 0.83 ± 0.21, <i>p</i> &lt; 0.05), whereas thiol/disulfide parameters did not differ between them (<i>p</i> &gt; 0.05). Significant correlations were observed between GAGS scores and IMA, NT, TT, and disulfide levels (<i>r</i> = -0.323, <i>p</i> = 0.005; <i>r</i> = 0.310, <i>p</i> = 0.007; <i>r</i> = 0.304, <i>p</i> = 0.008; <i>r</i> = 0.254, <i>p</i> = 0.028, respectively). The findings indicate oxidative stress contributes to AV pathogenesis, as evidenced by elevated IMA levels and a shift in thiol/disulfide homeostasis toward a more oxidant state. Although statistically significant correlations were found between oxidative stress markers and GAGS scores, the direction of these correlations was contrary to expectations, suggesting that there may not be a direct relationship between oxidative stress and disease severity.</p></div>","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of marital status with disease stage at presentation and disease-specific outcomes in cutaneous head and neck melanoma patients","authors":"Divya Sharma,&nbsp;Mitchell A. Taylor,&nbsp;Sierra I. Thomas,&nbsp;Bhavya Sharma,&nbsp;Patrick Tassone,&nbsp;Erin X. Wei","doi":"10.1007/s00403-025-04341-5","DOIUrl":"10.1007/s00403-025-04341-5","url":null,"abstract":"","PeriodicalId":8203,"journal":{"name":"Archives of Dermatological Research","volume":"317 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144880927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}