Applied Radiation and Isotopes最新文献_第3页

Recovered water - H218O from the 18F[FDG] production as liquid radioactive waste 从 18F[FDG] 生产中回收的水 - H218O 作为液态放射性废物。

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-19 DOI: 10.1016/j.apradiso.2025.111691

Magdalena Długosz-Lisiecka , Teresa Jakubowska

引用次数: 0

Development of a current measurement system for 4πγ ionization chamber

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-18 DOI: 10.1016/j.apradiso.2025.111684

Cong Chen , Weihua Zeng , Zhijie Yang , Shengli Hou , Juncheng Liang , Haoran Liu

引用次数: 0

Gravimetric drop-on-demand inkjet deposition for imaging phantoms with traceable activity

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-18 DOI: 10.1016/j.apradiso.2025.111683

Sean P. Jollota , Denis E. Bergeron , R. Michael Verkouteren , Svetlana Nour , Ryan P. Fitzgerald , Ohyun Kwon , Jeffrey L. Radtke , Bryan P. Bednarz , Brian W. Miller , Larry A. DeWerd

引用次数: 0

Integral cross section measurement of the 19F( γ, n)18F reaction for 12-20 MeV bremsstrahlung photons 12-20 MeV轫致辐射光子19F(γ, n)18F反应的积分截面测量。

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-18 DOI: 10.1016/j.apradiso.2025.111673

Shaima Akbar , M.M. Musthafa , C.V. Midhun , Swapna Lilly Cyriac , Resmi K. Bharathan , Silpa Ajaykumar , Antony Joseph , K.C. Jagadeesan

引用次数: 0

Assessment of the effectiveness of Monte Carlo Simulation for dose control at the Moroccan Boukhalef ionization facility

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-17 DOI: 10.1016/j.apradiso.2025.111682

Youssef El-ouardi , Adil Aknouch , Halima Jemmal

{"title":"Assessment of the effectiveness of Monte Carlo Simulation for dose control at the Moroccan Boukhalef ionization facility","authors":"Youssef El-ouardi , Adil Aknouch , Halima Jemmal","doi":"10.1016/j.apradiso.2025.111682","DOIUrl":"10.1016/j.apradiso.2025.111682","url":null,"abstract":"<div><div>Controlling the absorbed dose received by a target is a major challenge encountered during ionizing radiation applications. For experimentally measuring absorbed dose, dosimetric systems are used. On the other hand, in addition to experimental methods of dose measurement, there are other alternatives for calculating absorbed doses, these are numerical methods based on the Monte Carlo method which are very sophisticated and widely used throughout the world. The objective of this work is to demonstrate the effectiveness of Monte Carlo simulation for the contribution to dose control during the dosimetry operation at the Moroccan Boukhalef ionization facility (SIBO). In this study, a comparison is made between Monte Carlo simulation and a dose measurement experiment through the EPR/alanine dosimetry system. This comparison is made in terms of absorbed dose rate in a cylindrical shaped container filled with Expanded Polystyrene (EPS). The results obtained show a good agreement between the Monte simulation and the dose measurement experiment with differences not exceeding 6%. Therefore, Monte Carlo simulation is able to replace or complement experimental methods of dose measurements at the Moroccan Bokhlalef ionization facility.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111682"},"PeriodicalIF":1.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation spectroscopy of irradiated VVER-1200 fuel with burnable Am-absorber: A computational approach

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-16 DOI: 10.1016/j.apradiso.2025.111674

Sergey V. Bedenko , Gennady N. Vlaskin , Sergey D. Polozkov , Dmitry G. Veretennikov , Alexey S. Demin , Nima Ghal-Eh , Faezeh Rahmani

{"title":"Radiation spectroscopy of irradiated VVER-1200 fuel with burnable Am-absorber: A computational approach","authors":"Sergey V. Bedenko , Gennady N. Vlaskin , Sergey D. Polozkov , Dmitry G. Veretennikov , Alexey S. Demin , Nima Ghal-Eh , Faezeh Rahmani","doi":"10.1016/j.apradiso.2025.111674","DOIUrl":"10.1016/j.apradiso.2025.111674","url":null,"abstract":"<div><div>Safe storage of fresh and irradiated fuel is ensured by solving the problem of photon emission protection. The neutron component is usually not taken into account due to its low intensity. However, for the new VVER-1200 fuel, the neutron component consideration is a mandatory procedure for radiation safety. In this study, the radiation dose was calculated for a fuel consisting of UO<sub>2</sub> with a heterogeneous distribution of Am<sub>2</sub>O<sub>2</sub> microcapsules, and the (α, n) component of the neutron background was evaluated. A comparative analysis of radiation characteristics of fuel assemblies shows that there is a significant excess in both the neutron and the photon components of the fuel under study. The yield and dose of neutrons from Am−containing fuel exceed those of uranium−based fuels by a factor of two, and when calculating the dose, it is necessary to take into account the energy spectrum of (α, n) neutrons in Am<sub>2</sub>O<sub>2</sub> microcapsules. The analysis of the impact of Am on the photon component indicates that ensuring radiation safety for both fresh and irradiated fuels necessitates addressing challenges associated with photon radiation protection. This study aims to establish comprehensive procedures and guidelines for the handling of novel fuel materials during both production and post-irradiation processes within the reactor environment.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111674"},"PeriodicalIF":1.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heterogeneous head phantom for validating treatment planning system in boron neutron capture therapy

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-16 DOI: 10.1016/j.apradiso.2025.111681

Yi-Lian Wang , Wei-Lin Chen , Zhao-Ming Pan , Rong-Jiun Sheu

{"title":"Heterogeneous head phantom for validating treatment planning system in boron neutron capture therapy","authors":"Yi-Lian Wang , Wei-Lin Chen , Zhao-Ming Pan , Rong-Jiun Sheu","doi":"10.1016/j.apradiso.2025.111681","DOIUrl":"10.1016/j.apradiso.2025.111681","url":null,"abstract":"<div><div>In clinical boron neutron capture therapy (BNCT), the distribution of dose to a heterogeneous medium that is predicted by a treatment planning system (TPS) should be experimentally validated. A head phantom specifically developed for this purpose is described and demonstrated herein. The cylindrical phantom exhibits distinct regions made from four materials (polymethyl methacrylate, calcium phosphate, air, and boric acid) to approximate a head structure with explicitly defined skin, skull, and brain tissue with a cavity and tumor within. Multiple gold activation wires were consecutively embedded in the phantom along the neutron beam central axis to provide direct measurements of <sup>197</sup>Au(n,γ)<sup>198</sup>Au reaction rates at various depths and interfaces, enabling comparison with numerical predictions. The heterogeneous head phantom was irradiated and tested at the Tsing Hua Open-pool Reactor BNCT facility, and the measured reaction rates were compared with the results of two calculation methods: Monte Carlo simulations based on an analytical geometry model and TPS predictions based on voxel-based geometry created from computed tomography images. The specifications of the phantom and reported results can serve as a reference suite of test problems for BNCT dosimetry.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111681"},"PeriodicalIF":1.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression rate of LAT1 in high-grade parotid gland carcinoma and potential of BNCT as a treatment option for recurrent parotid gland carcinoma 高级别腮腺癌中LAT1的表达率及BNCT作为复发性腮腺癌治疗选择的潜力

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-13 DOI: 10.1016/j.apradiso.2025.111657

Yusuke Kikuoka , Teruhito Aihara , Masaaki Higashino , Yoshitaka Kurisu , Shin-ichi Haginomori , Keiji Nihei , Koji Ono

{"title":"Expression rate of LAT1 in high-grade parotid gland carcinoma and potential of BNCT as a treatment option for recurrent parotid gland carcinoma","authors":"Yusuke Kikuoka , Teruhito Aihara , Masaaki Higashino , Yoshitaka Kurisu , Shin-ichi Haginomori , Keiji Nihei , Koji Ono","doi":"10.1016/j.apradiso.2025.111657","DOIUrl":"10.1016/j.apradiso.2025.111657","url":null,"abstract":"<div><h3>Purpose</h3><div>Boron neutron capture therapy (BNCT) perform as a treatment option for locally advanced or recurrent unresectable head and neck cancers since June 2020 in Japan. The effect of BNCT on parotid carcinoma, which presents a variety of histologic types, remains unclear. The object of this study was to investigate the antitumor efficacy of BNCT against parotid gland carcinoma by focusing on LAT1, which is involved in the uptake of L-BPA, the boron compound used in BNCT.</div></div><div><h3>Materials and methods</h3><div>We performed a retrospective review of 42 high-grade parotid gland carcinoma cases. We immunostained specimens using an anti-LAT1 monoclonal antibody to assess the LAT1 expression rate. We divided the patients into two groups: LAT1 expression rate below 10% (negative group) and 10% or higher (positive group), and performed a survival rate analysis.</div></div><div><h3>Results</h3><div>The study included 42 patients categorized by histological three type into mucoepidermoid carcinoma (MEC), salivary duct carcinoma (SDC), and adenoid cystic carcinoma (AdCC). The LAT1 expression rate in the 42 cases was 37.5%, and the rates for each histological type were: AdCC 15.0%; MEC 17.5%; and SDC 60.0%. The 5-year disease-free survival (DFS) rates were 46.8% in the positive group and 81.8% in the negative group (p = 0.17).</div></div><div><h3>Conclusions</h3><div>The LAT1 expression rate was 37.5% in cases of high-grade parotid gland carcinoma, and SDC exhibited particularly high expression. From the perspective of LAT1 expression, our results indicated that L-BPA-based BNCT is likely to achieve therapeutic efficacy against parotid gland carcinoma.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111657"},"PeriodicalIF":1.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shielding design and heat transfer analysis of the transportation container of a hot batch in the 99Mo production facility 99Mo生产装置热批运输容器屏蔽设计及传热分析

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-13 DOI: 10.1016/j.apradiso.2025.111672

Abouzar Kiyani , Ali Bahrami Samani , Reza Pourimani , Seyed Milad Miremad

{"title":"Shielding design and heat transfer analysis of the transportation container of a hot batch in the 99Mo production facility","authors":"Abouzar Kiyani , Ali Bahrami Samani , Reza Pourimani , Seyed Milad Miremad","doi":"10.1016/j.apradiso.2025.111672","DOIUrl":"10.1016/j.apradiso.2025.111672","url":null,"abstract":"<div><div>In molybdenum-99 (<sup>99</sup>Mo) production facilities via the fission method, appropriate transportation containers must be used to transfer irradiated targets from the irradiation facility to the processing facility, following the requirements for transferring radioactive materials. In the <sup>99</sup>Mo production industrial plan of Iran, the transportation container must be capable of carrying a holster containing nine irradiated low-enriched uranium targets, known as a hot batch. In this article, the proper shielding of two-layer containers based on the gamma spectrum emitted from the radioisotope inventory of a local hot batch, including fission products, activation products, and other radioisotopes produced from their decay chains, was investigated by using Monte Carlo code MCNP6. The simulation results indicated that a two-part container including a moving part of depleted uranium with a thickness of 7 cm and a fixed part of lead with a thickness of 7.2 cm could be an appropriate choice for the local hot batch transport. Also, heat transfer analysis using ANSYS software showed that transporting the hot batch immersed in water inside the container improved thermal distribution.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111672"},"PeriodicalIF":1.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

“Nanoparticle-based sensitizers in prostate cancer treatment: Enhancing radiotherapy efficacy through innovative nanotechnology: Narrative review” 纳米颗粒致敏剂在前列腺癌治疗中的应用：通过创新纳米技术提高放疗疗效：叙述性综述。

IF 1.6 3区工程技术

Applied Radiation and Isotopes Pub Date : 2025-01-12 DOI: 10.1016/j.apradiso.2025.111671

Mohsen Shafiee , Elahe Soltani Fard , Sina Taghvimi , Ahmad Movahedpour , Pegah Mousavi , Seyed Masoud Rezaeijo , Seyyed Hossein Khatami , Omid Azadbakht

{"title":"“Nanoparticle-based sensitizers in prostate cancer treatment: Enhancing radiotherapy efficacy through innovative nanotechnology: Narrative review”","authors":"Mohsen Shafiee , Elahe Soltani Fard , Sina Taghvimi , Ahmad Movahedpour , Pegah Mousavi , Seyed Masoud Rezaeijo , Seyyed Hossein Khatami , Omid Azadbakht","doi":"10.1016/j.apradiso.2025.111671","DOIUrl":"10.1016/j.apradiso.2025.111671","url":null,"abstract":"<div><div>For men with localized prostate cancer, radiotherapy (RT) remains a common therapeutic option. Although radiotherapy has had significant success, it remains an intractable issue in promoting radiation damage to tumor tissue while reducing adverse effects on healthy tissue. Chemicals or pharmacological substances known as radiosensitizers can increase the killing effect on tumor cells by accelerating DNA damage and indirectly producing free radicals. Of all the approaches to improving RT management outcomes, metal nanoparticle-enhanced radiation for prostate cancer patient therapy is a unique strategy that has sparked scientific attention in the past decade. Most current data is based on targeted RT with gold nanoparticles, among the most studied materials. Nevertheless, several novel materials have also been employed in preclinical settings. This study assesses existing dosimetric data on prostate cancer tissue as well as the likely future influence on treatment options and patient outcomes since further research in a clinical setting is necessary.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"218 ","pages":"Article 111671"},"PeriodicalIF":1.6,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0