Annals of Indian Academy of Neurology最新文献_第6页

MEG or No MEG, That is the Question. "MEG，还是没有 MEG，这是一个问题"。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-09-01 Epub Date: 2024-10-17 DOI: 10.4103/aian.aian_830_24

Chaturbhuj Rathore

引用次数: 0

Atypical Bilateral Posterior Semicircular Canalolithiasis - A Case Series. 非典型双侧后半规管结石--一个病例系列。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-08-01 DOI: 10.4103/aian.aian_387_24

Ajay K Vats, Shreya Vats, Sudhir Kothari, Nishant Aswani

{"title":"Atypical Bilateral Posterior Semicircular Canalolithiasis - A Case Series.","authors":"Ajay K Vats, Shreya Vats, Sudhir Kothari, Nishant Aswani","doi":"10.4103/aian.aian_387_24","DOIUrl":"https://doi.org/10.4103/aian.aian_387_24","url":null,"abstract":"Abstract: Barany Society includes bilateral typical posterior semicircular canal benign paroxysmal positional vertigo (PSC-BPPV) in its classification of multicanal subtype. In the past decade, less-common and atypical subtypes of PSC-BPPV, like short-arm and non-ampullary arm posterior semicircular canalolithiasis, have emerged, requiring the conduct of conventional and auxiliary positional tests on both sides to uncover their bilaterality. Authors hereby report three atypical less-common subtypes of bilateral PSC-BPPV, discussing their clinicodemographic profiles, management by repositioning maneuvers and physical therapy, and follow up. Both Case 2 and Case 3 are precisely tri-canalolithiasis (bilateral ampullary arm posterior semicircular canalolithiasis with co-occurring right non-ampullary arm posterior semicircular canalolithiasis in Case 2 and bilateral short arm with co-occurring left ampullary arm posterior semicircular canalolithiasis in Case 3), which has not been reported previously in the literature. There has been only one previously reported case of bilateral non-ampullary arm semicircular canalolithiasis, and it is now observed in Case 1.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurodevelopmental Disorder with Severe Motor Impairment and Absent Language (NEDMIAL) Due to DHX30 Mutations: First Indian Report of Two Cases. DHX30 基因突变导致的严重运动障碍和无语言的神经发育障碍（NEDMIAL）：印度首次报告的两例病例。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-16 DOI: 10.4103/aian.aian_253_24

Pradeep Kumar Gunasekaran, Yashu Sharma, Vikas Bhatia, Arushi Gahlot Saini

引用次数: 0

Safety and Efficacy of Newer Oral Anticoagulants Versus Vitamin K Antagonists in the Management of Cerebral Venous Thrombosis: A Single-Center Ambispective Study from South India. 新型口服抗凝剂与维生素 K 拮抗剂治疗脑静脉血栓的安全性和有效性：印度南部单中心前瞻性研究》。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-06-21 DOI: 10.4103/aian.aian_1096_23

Rithvik Ramesh, Lakshmi Narasimhan Ranganathan, Sriram Raguraman, Kamlesh Jayakumar, Braveen Rajamanoharan, Varun Kishore Loganathan, Philo Hazeena, Sundar Shanmugam, Deepa Avadhani, Karthik Sankar

{"title":"Safety and Efficacy of Newer Oral Anticoagulants Versus Vitamin K Antagonists in the Management of Cerebral Venous Thrombosis: A Single-Center Ambispective Study from South India.","authors":"Rithvik Ramesh, Lakshmi Narasimhan Ranganathan, Sriram Raguraman, Kamlesh Jayakumar, Braveen Rajamanoharan, Varun Kishore Loganathan, Philo Hazeena, Sundar Shanmugam, Deepa Avadhani, Karthik Sankar","doi":"10.4103/aian.aian_1096_23","DOIUrl":"10.4103/aian.aian_1096_23","url":null,"abstract":"Introduction: Cerebral Venous Thrombosis (CVT) poses a rare but life-threatening challenge, warranting meticulous treatment approaches. Traditional therapy involves Vitamin K Antagonists (VKAs), but Newer Oral Anticoagulants (NOACs) offer potential advantages. This study addresses a crucial knowledge gap in the Indian context, analyzing real-world data to guide CVT management decisions.Methods: A single-center, ambispective cohort study included consecutive adult CVT patients. Data collection encompassed demographics, clinical data, imaging, and treatment details. Patients were categorized into VKA and NOAC groups. Outcomes measured recanalization status, functional outcomes, bleeding events, and adverse drug reactions.Results: Among 181 enrolled patients, NOAC-treated (Group B) individuals had significantly higher rates of complete recanalization (58.5% vs. 31.1%) with a similar incidence of adverse events and also displayed better functional outcomes at weeks 8 and 12 compared to VKA-treated (Group A) patients. Recurrent thromboembolic events were absent in both groups during follow-up.Conclusion: This study highlights NOACs' potential advantages in CVT management, including improved functional outcomes, enhanced recanalization, and similar bleeding risk. Adverse events were milder with NOACs. While acknowledging limitations, these findings support NOACs as a promising alternative to VKAs, advancing CVT care and outcomes.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombolysis for Ischemic Stroke Despite Recent Ingestion of Direct Oral Anticoagulants - A Growing Dilemma Also in India. 尽管最近服用了直接口服抗凝剂，缺血性脑卒中仍需溶栓治疗--这在印度也是一个日益严重的难题。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-20 DOI: 10.4103/aian.aian_524_24

Thomas R Meinel, Naveen K Paramasivan, Bijoy K Menon, Urs Fischer, David J Seiffge

{"title":"Thrombolysis for Ischemic Stroke Despite Recent Ingestion of Direct Oral Anticoagulants - A Growing Dilemma Also in India.","authors":"Thomas R Meinel, Naveen K Paramasivan, Bijoy K Menon, Urs Fischer, David J Seiffge","doi":"10.4103/aian.aian_524_24","DOIUrl":"10.4103/aian.aian_524_24","url":null,"abstract":"The administration of intravenous thrombolysis (IVT) for patients with acute ischemic stroke who have recently ingested direct oral anticoagulants (DOACs) presents a clinical challenge due to the perceived increased risk of intracranial hemorrhage (ICH). Traditional guidelines from the US and European authorities advise against IVT within 48 h of last DOAC ingestion, unless specific coagulation tests indicate safety. However, emerging observational studies suggest that IVT might be safe in selected patients. A US stroke registry study and a global multicenter cohort study both reported no significant increase in symptomatic ICH among patients on DOACs compared to those not on anticoagulants. A systematic review of all published observational studies further supported these findings, showing comparable bleeding rates and functional outcomes in DOAC-treated patients. Reversal agents like idarucizumab for dabigatran have demonstrated potential in facilitating safer IVT administration, though logistical and cost-related barriers limit their widespread use. The variability in global guidelines reflects differing approaches to risk assessment and resource availability, highlighting the need for individualized treatment decisions. In India, the increasing prevalence of atrial fibrillation and stroke as well as prescription of DOACs necessitate adapted guidelines that consider local health-care infrastructure. Despite the promising observational data, the lack of randomized controlled trials underscores the need for further research to establish robust evidence for IVT use in this context. Collaborative international efforts and inclusion of diverse patient populations in future studies will be crucial to refine treatment protocols and improve outcomes for stroke patients on DOACs.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142085949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote Intracerebral Haemorrhage Secondary to Vessel Rupture Following Bridging Intravenous Thrombolysis (Causal or Incidental) with Successful Endovascular Treatment: A Rare Case Report. 静脉溶栓（因果或偶然）与血管内治疗成功衔接后，血管破裂继发远端脑出血：罕见病例报告。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-23 DOI: 10.4103/aian.aian_285_24

Piyush Ojha, Gaurav Goel, Mandar Waghralkar, Anshu Mahajan

引用次数: 0

Cervical Artery Dissection: Clinical Outcomes and Functional Outcome Predictors from a Tertiary Care Center in India. 颈动脉离断：来自印度一家三级医疗中心的临床结果和功能性结果预测指标。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-07-18 DOI: 10.4103/aian.aian_134_24

Ayush Agarwal, Ajay Garg, Yamini Antil, Rohit Bhatia, Leve Joseph, Agrata Sharma, Sushant Agarwal, Ashish Upadhyay, Venugopalan Y Vishnu, M V Padma Srivastava

引用次数: 0

LEUDEN Syndrome: A Novel Hypomyelinating Leukoencephalopathy in a 1-Year-Old Girl. LEUDEN 综合征：一名 1 岁女童的新型骨髓抑制性白质脑病

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-16 DOI: 10.4103/aian.aian_257_24

Singanamalla Bhanudeep, Bramhini Bhargavi Koneti

引用次数: 0

Study of Language Function in Bengali-Speaking Population with Motor Neuron Disease. 孟加拉语运动神经元疾病患者的语言功能研究

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-08 DOI: 10.4103/aian.aian_44_24

Siladitya Das, Debal Laha, Prasenjit Sengupta

{"title":"Study of Language Function in Bengali-Speaking Population with Motor Neuron Disease.","authors":"Siladitya Das, Debal Laha, Prasenjit Sengupta","doi":"10.4103/aian.aian_44_24","DOIUrl":"10.4103/aian.aian_44_24","url":null,"abstract":"Background: Motor neuron diseases (MNDs) have been traditionally considered to spare cognition. But recent findings show that multiple domains of cognition including language can be involved in MND patients. Most studies on language patterns of MND patients were conducted in Western nations, but data on Indian population is limited. This study is an attempt to explore the language functions of Bengali-speaking MND patients from this part of eastern India.Objective: To determine the prevalence and nature of language dysfunction in MND patients.Materials and methods: A single-center, hospital-based, observational, cross-sectional study. The Bengali adaptation of the Western Aphasia Battery was administered to 50 cases diagnosed with MND, attending a tertiary care hospital consecutively over a 1-year period, and fulfilling the inclusion and exclusion criteria for the study. Descriptive and inferential statistics were used for expressing results.Results: Eighteen percent of cases showed impairments in spontaneous speech. Fluency was impaired in 72%, and 22% cases showed impaired naming. Moreover, 20% and 26% of cases were impaired in repetition and comprehension, respectively. Reading and writing was impaired in 16% and 26% of cases, respectively. Significant difference was found in the primary language skill scores and aphasia quotient across age groups, while no significant difference was found in these scores across education status.Conclusions: This study describes the language profiles of Bengali-speaking MND patients from eastern India, and the findings are similar to previous research works, which have shown morpho-syntactic, lexical-semantic, and phonological errors in language function.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification and Clinical Correlation of Posterior Cranial Fossa Cerebrospinal Fluid Volume in Primary Hemifacial Spasm Using Magnetic Resonance Imaging. 利用磁共振成像对原发性面肌痉挛患者颅后窝脑脊液容量进行量化并与临床相关性分析

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-07-12 DOI: 10.4103/aian.aian_199_24

Dds Anudeep, Karthik Kulanthaivelu, Vikram V Holla, Nitish Kamble, Ravi Yadav, Pramod Kumar Pal, Rohan R Mahale

{"title":"Quantification and Clinical Correlation of Posterior Cranial Fossa Cerebrospinal Fluid Volume in Primary Hemifacial Spasm Using Magnetic Resonance Imaging.","authors":"Dds Anudeep, Karthik Kulanthaivelu, Vikram V Holla, Nitish Kamble, Ravi Yadav, Pramod Kumar Pal, Rohan R Mahale","doi":"10.4103/aian.aian_199_24","DOIUrl":"10.4103/aian.aian_199_24","url":null,"abstract":"Background and objective: Primary hemifacial spasm (HFS) is caused by neurovascular conflict (NVC) at the root entry zone of the facial nerve. Whether reduction of posterior cranial fossa (PCF) cerebrospinal fluid (CSF) volume is a risk factor for HFS is not clear. The study aims at the radiologic assessment of PCF CSF volume and its clinical correlation.Methods: A cross-sectional, hospital-based, case-control study was conducted, in which 50 cases of primary HFS and 50 age- and sex-matched controls were recruited. PCF CSF volume was quantified in 3-T brain magnetic resonance imaging.Results: The mean age at presentation of cases was 50.7 ± 10.7 years (42-69 years) and controls was 52.4 ± 8.7 years (45-68 years). The mean duration of symptoms was 3.5 ± 1.3 years (1.5-8 years). About 52% of patients had grade 2 (mild) severity of HFS. The mean PCF CSF volume of patients was 13,725.1 ± 909.5 mm 3 and controls was 14,458.5 ± 973.5 mm 3 ( P < 0.001). The mean PCF CSF volume of females with HFS was 13,714.8 ± 852.5 mm 3 and female controls was 14,521.8 ± 973.5 mm 3 ( P = 0.006). PCF CSF volume was significantly associated with the presence of HFS ( P = 0.007), the severity of HFS ( P < 0.001), and the presence of NVC ( P = 0.02).Conclusion: PCF CSF volume was lesser in HFS patients and was associated with the presence of HFS, the severity of HFS, and the presence of NVC. Females with HFS had smaller PCF CSF volume. Small PCF CSF volume is a risk factor for HFS, particularly in females with HFS.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0