Annals of Indian Academy of Neurology最新文献_第10页

Evolution of Sleep Apnea and Arousals in Patients with Ischemic Stroke: A Longitudinal Follow-Up Study. 缺血性脑卒中患者睡眠呼吸暂停和觉醒的演变：一项纵向随访研究。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-05 DOI: 10.4103/aian.aian_439_24

P R Srijithesh, Sivasubramanian Mythirayee, Doniparthi Venkata Seshagiri, Nitish L Kamble, Sanjib Sinha, Ravi Yadav

{"title":"Evolution of Sleep Apnea and Arousals in Patients with Ischemic Stroke: A Longitudinal Follow-Up Study.","authors":"P R Srijithesh, Sivasubramanian Mythirayee, Doniparthi Venkata Seshagiri, Nitish L Kamble, Sanjib Sinha, Ravi Yadav","doi":"10.4103/aian.aian_439_24","DOIUrl":"10.4103/aian.aian_439_24","url":null,"abstract":"Background and objectives: Sleep-disordered breathing (SDB) is characterized by pauses or shallow breathing during sleep. It is linked to poorer outcomes and increased stroke recurrence in stroke patients. We aimed to evaluate the proportion, severity, type, and evolution of SDB and arousals in ischemic stroke patients.Methods: Ischemic stroke patients were recruited to evaluate SDB. Patients underwent overnight polysomnography (PSG) twice - within 1 month of stroke onset and again after 3 months. Clinical outcomes were evaluated at 6, 18, and 24 months.Results: Of 141 acute ischemic stroke patients screened, 111 patients recruited in the study and 105 patients had technically adequate polysomnography. The mean age of patients was 50.5 years (standard deviation [SD]: 12.30), 78.4% of the patients were males, and the mean body mass index was 26 (SD: 5.4). Results showed that 81.9% had an apnea-hypopnea index (AHI) ≥5, with 12.5% having an AHI >30. The median arousal index (ArI) was 15.4 (interquartile range [IQR]: 0.5-50.5), which increased as the apnea increased. During follow-up, 56.8% patients had an AHI ≥5, with 12.5% having severe apnea. The median ArI decreased from 15.4 (IQR: 0.5-50.5) initially to 11.54 (IQR: 0.5-21.1) at follow-up. Numerical change in AHI severity categories were noted during the follow-up (mild: 8 vs 15; moderate: 17 vs 11; severe 19vs 7). For AHI >30, ArI decreased from 24.63 (IQR: 0.7-50.05) to 10.54 (IQR: 7.1-15.07) at follow-up. Sleep efficiency and rapid eye movement (REM) sleep duration increased on follow-up.Conclusions: The study showed a high proportion of SDB in acute ischemic stroke patients. In the follow-up, SDB improved, as reflected in AHI and ArI changes.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"651-656"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Broad Autism Phenotype Questionnaire - Translation and Validation in a South Indian Language. 广泛的自闭症表型问卷-翻译和验证在南印度语言。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-06 DOI: 10.4103/aian.aian_147_24

Betsy Baby, Sandhya Pushpagiri, P Ravi Prasad Varma, L S Saritha, S J Dhiya, Shoba S Meera, M Rekha, Manju Mohan, Soumya Sundaram

{"title":"Broad Autism Phenotype Questionnaire - Translation and Validation in a South Indian Language.","authors":"Betsy Baby, Sandhya Pushpagiri, P Ravi Prasad Varma, L S Saritha, S J Dhiya, Shoba S Meera, M Rekha, Manju Mohan, Soumya Sundaram","doi":"10.4103/aian.aian_147_24","DOIUrl":"10.4103/aian.aian_147_24","url":null,"abstract":"Background and objectives: Broad Autism Phenotype (BAP) refers to specific behaviors or minor deficits in social/communication skills not meeting the diagnostic criteria for autism spectrum disorders (ASDs). The BAP Questionnaire (BAPQ) measures aloof personality (AP), rigid personality (RP), and pragmatic language (PL) deficits of BAP. The study objective is to translate and validate BAPQ into Malayalam, a South Indian language, and to establish new cut-off scores for detecting BAP in the Indian population.Methods: BAPQ was translated into Malayalam (BAPQ-M), following which it was tested for reliability and internal consistency and factor analysis was conducted in 40 parents of ASD and neurotypical children. The receiver operating characteristic curve analysis generated new cut-off scores.Results: The content validity index was ≥ 0.8 for each item. For the self and informant versions, Cronbach's α was 0.753 and 0.807, respectively, while Spearman's correlation coefficient was 0.953 ( P < 0.001) and 0.918 ( P < 0.001). The items demonstrated good communality (0.532-0.870), and on factor rotation, 12 components had eigenvalues > 1, which explained 72.3% of the total variance. The new cut-off scores for total estimate, AP, RP, and PL subscales were 2.60 (sensitivity 0.825; specificity 0.575; odds ratio [OR] 6.38, 95% confidence interval [CI] 2.28-17.84; P < 0.001), 2.60 (sensitivity 0.60; specificity 0.75; OR 4.50, 95% CI 1.73-11.70; P 0.002), 2.90 (sensitivity 0.8; specificity 0.475; OR 3.62, 95% CI 1.342-9.77; P 0.011), and 2.70 (sensitivity 0.5; specificity 0.825; OR 4.71, 95% CI 1.69-13.13; P 0.003), respectively.Conclusions: BAPQ-M has good psychometric properties for determining the presence of BAP among the people of Kerala, a South Indian state.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"668-676"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Learning Curve - A Neurosurgeon's Memoir. 学习曲线——一位神经外科医生的回忆录。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-17 DOI: 10.4103/aian.aian_882_24

Venkataraman Sundaram

引用次数: 0

Piriformis Syndrome as a Cause of Non-discogenic Sciatic Pain in a Young Bharatanatyam Dancer. 一名年轻的印度印度舞蹈演员因梨状肌综合症而导致非盘源性坐骨神经痛。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-09-09 DOI: 10.4103/aian.aian_401_24

Thomas Mathew, Akshata Huddar, Shagun Bhardwaj, Sharath Kumar Goddu Govindappa

引用次数: 0

Posterior Circulation Stroke Due to Arterial Thoracic Outlet Syndrome: A Case Report and Literature Review. 动脉胸廓出口综合征所致后循环卒中1例报告及文献复习。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-02 DOI: 10.4103/aian.aian_442_24

Raiz Iqbal, V Sriramakrishnan, S Saravanan, K Rajesh, F Jason Ambrose, R Nandini

引用次数: 0

Tyrosine Kinase Inhibitor-Induced Intracranial Artery Stenosis - A Rare Cause of TIA in a Patient of Chronic Myeloid Leukemia. 酪氨酸激酶抑制剂诱发的颅内动脉狭窄--慢性髓性白血病患者发生 TIA 的罕见原因。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-10-08 DOI: 10.4103/aian.aian_411_24

Sumedh S Agrawal, Nikith A Shetty, Nisha Shenoy, Arvind N Prabhu, Aparna R Pai

引用次数: 0

Developing an Index to Measure the Value of Health Care Provided to Stroke Patients. 制定衡量中风患者医疗保健价值的指数。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-11-19 DOI: 10.4103/aian.aian_1084_23

Halil Şengül, Sabahattin Aydın, Emrah Önder, Arzu Bulut

{"title":"Developing an Index to Measure the Value of Health Care Provided to Stroke Patients.","authors":"Halil Şengül, Sabahattin Aydın, Emrah Önder, Arzu Bulut","doi":"10.4103/aian.aian_1084_23","DOIUrl":"10.4103/aian.aian_1084_23","url":null,"abstract":"Background and objectives: It is possible to evaluate health services for stroke patients based on clinical benefits. However, in recent years, questions about responsiveness and outcomes have also emerged. Currently, there is no index that can assess health-care services for stroke patients along these three dimensions. This study introduces the first index designed to measure the value generated by health-care services for stroke patients.Methods: The Case-Mix Variables Data Collection Reference Guide, developed through a review of national and international stroke guidelines, underwent content validation by 10 neurologists and 10 interventional radiologists. Questions with a content validity index exceeding 0.80, along with the World Health Organization responsiveness questionnaire and the Patient-Reported Outcomes Measurement Information System Global-10 short form, were subjected to pairwise comparison by two neurologists, two interventional radiologists, and two public health physicians using the analytic hierarchy process (AHP) method.Results: In the comprehensive ranking of questions formulated using the AHP method and assessed by experts for importance and global weights, new stroke follow-up emerged as the most crucial, garnering an index score of 0.09. Conversely, questioning patients about their alcohol use status was deemed the least significant by experts, registering an index score of 0.00021.Conclusions: Our AHP analyses have furnished an index for gauging the factors that contribute to the value of health-care services rendered to stroke patients.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"695-705"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Prospective Single-Arm Cohort Study of Immune-mediated Seizures/Epilepsy Without Encephalopathy (ISEWE) in Children from a Tertiary Care Hospital in South India. 一项来自南印度三级医院的儿童免疫介导的癫痫发作/无脑病癫痫（ISEWE）的前瞻性单臂队列研究

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-13 DOI: 10.4103/aian.aian_408_24

Basavanagowda Thanuja, Mahesh Kamate

{"title":"A Prospective Single-Arm Cohort Study of Immune-mediated Seizures/Epilepsy Without Encephalopathy (ISEWE) in Children from a Tertiary Care Hospital in South India.","authors":"Basavanagowda Thanuja, Mahesh Kamate","doi":"10.4103/aian.aian_408_24","DOIUrl":"10.4103/aian.aian_408_24","url":null,"abstract":"Acute-onset seizures in children pose a diagnostic and therapeutic dilemma. Some epilepsy cases presenting with seizures but without encephalopathy, though treatable with immunotherapy, are often missed due to lack of suspicion of immune mechanism in the context of absent encephalitis. A prospective study was conducted on premorbidly normal children with new-onset seizures occurring in clusters, with normal neuroimaging. Investigations included electroencephalogram (EEG), cerebrospinal fluid examination, and testing for autoantibodies. All cases received methylprednisolone pulse therapy along with antiseizure medications (ASMs), followed by monthly dexamethasone oral pulse therapy. Fifteen cases were enrolled (11 males, four females). Mean age at seizure onset was 4.6 years. Focal seizures were present in 13/15 (86.7%) cases. Magnetic resonance imaging of the brain was normal in all. EEG showed interictal epileptiform discharges in 12 cases (focal in nine) and ictal record in two cases. On monthly oral steroids, number of ASMs could be reduced. Eight cases never had a relapse, while seven did have it. Relapses were more common if more than three ASMs were tried and less if steroids were started within 30 days. Immune-mediated seizures/epilepsy without encephalopathy is a new, important, and treatable entity. Early diagnosis and institution of immunotherapy results in significant improvement in seizure control and also reduces the need for long-term polytherapy. Awareness of this entity is crucial, especially when premorbidly normal children present with new-onset clusters of refractory seizures.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"710-714"},"PeriodicalIF":1.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Acute Disseminated Encephalomyelitis (RADEM) Presenting Beyond "Sixteen-and-a-Half Syndromes". 复发性急性播散性脑脊髓炎（RADEM）表现超过“十六和半综合征”。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-12-04 DOI: 10.4103/aian.aian_468_24

Baiakmenlang Synmon, Shri Ram Sharma, Mahendre Thakre, Ayush Jain, Sri Hari J

引用次数: 0

Late-Onset Presentation of Spastic Paraplegia 3A ( ATL1 -HSP) and Its Rare Occurrence with Multiple Spinal Neurofibromas. 迟发性痉挛性截瘫 3A（ATL1-HSP）及其罕见的多发性脊髓神经纤维瘤。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-11-01 Epub Date: 2024-11-12 DOI: 10.4103/aian.aian_308_24

Anudeep Ds Davuluri, Sangeeth T Ananthasubramanian, Saraswati Nashi, Faheem Arshad, Hansashree Padmanabha, Seena Vengalil, Rohan Mahale, Pooja Mailankody, P R Srijithesh, Girish B Kulkarni, Mathuranath S Pavagada, Suvarna Alladi, Atchayaram Nalini

引用次数: 0