Annals of Indian Academy of Neurology最新文献

{"title":"Jaw-Opening Myoclonus: A Rare and Distinctive Sign in Subacute Sclerosing Panencephalitis.","authors":"Bhavani Madduluri, Suryaprabha Turaga, Yenni Harika, Sabeeha Naaz, S Arun","doi":"10.4103/aian.aian_1075_24","DOIUrl":"10.4103/aian.aian_1075_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"469-471"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Electrical Evolution of \"Pseudo\" Spike-Wave Activation in Sleep EEG Patterns in Self-Limited Childhood Epilepsies.","authors":"Neetha Balaram, Smita Balachandran, Abdul V Gafoor, S R Ratheesh","doi":"10.4103/aian.aian_899_24","DOIUrl":"10.4103/aian.aian_899_24","url":null,"abstract":"<p><strong>Abstract: </strong>The purpose of this study was to identify the pseudo spike-wave activation in sleep (SWAS) patterns in the electroencephalogram (EEG) of self-limited focal epilepsies of childhood (SeLFE) and study their clinical and electrical evolution. Sleep EEG and clinical data of children aged 2-12 years with SeLFE and pseudo-SWAS were collected retrospectively from our EEG database and were followed periodically every 6 months with clinical, EEG, and neurocognitive assessments. Nine children were identified and were grouped as follows: (a) pseudo-SWAS pattern caused by type 1 occipitofrontal spikes in five children, who had no clinical worsening on follow-up, and this pattern resolved within 3 years; (b) pseudo-SWAS pattern without occipitofrontal spikes in three children that was caused by diffusion of pre-existing focal spikes; and (c) pseudo-SWAS pattern induced by antiseizure medication in one child, which completely resolved on withdrawing the medication. Electro-clinical dissociation occurred in pseudo-SWAS, and none of them evolved to developmental and/or epileptic encephalopathy with SWAS. Identification of these patterns helps to avoid inadvertent use of antiseizure medications and immunomodulators.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"426-431"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Cardiac Assessment in Idiopathic Inflammatory Myopathies.","authors":"Sruthi S Nair","doi":"10.4103/aian.aian_543_25","DOIUrl":"10.4103/aian.aian_543_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":"28 3","pages":"344-345"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction Tasks in Diagnosis of Early Cognitive Impairment - A Critical Revisitation.","authors":"Sayooja Sachithanandan, P K Parvathy, S R Sushama, P G Rajesh, Meenu Surendran, Anjali Suku, Prinu Jose, Jeemon Panniyammakal, Ravi Prasad Varma, Ramshekhar N Menon","doi":"10.4103/aian.aian_1000_24","DOIUrl":"10.4103/aian.aian_1000_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>This study aimed to look at the utility of the clock drawing test (CDT) and cube construction test (CCT) in diagnosing early cognitive impairment (ECI) and the correlations among various demographic variables and neuropsychological tests.</p><p><strong>Methods: </strong>This is a retrospective study with data collected from an ongoing registry. Elderly with at least 8 years of formal education were categorized into cognitively normal (CN), mild cognitive impairment (MCI), and early dementia (ED) as per established criteria. Their CDT and CCT scores were assessed using a scoring system and errors were also analysed by the principal investigator blinded to the clinical diagnosis.</p><p><strong>Results: </strong>A total of 228 subjects with a mean age of 69 ± 6.7 years were categorized into three groups: 80 CN subjects, 77 with MCI, and 71 with ED. Age was negatively and the level of education was positively correlated to CDT and CCT scores among CN, but not in ECI. Qualitative errors on CDT included significantly more graphic, spatial, and conceptual errors and stimulus-bound responses among ED compared to CN and the latter two error subsets compared to MCI. Logistic regression revealed that higher age and lower quantitative CDT scores were independent predictors for classifying ECI from CN. The addition of qualitative errors of CDT rendered a greater effect size in classifying ED from MCI and CN.</p><p><strong>Conclusions: </strong>CDT and CCT scores performed better in diagnosing ED and MCI from CN. CDT scored better as a diagnostic tool than CCT possibly due to better objectivity in the scoring system with qualitative information.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"406-413"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic Variations in Clinical Presentations of Paramyotonia Congenita in Two Brothers.","authors":"Kamalesh Tayade, Vishakha Ghadi, Dynaneshwar Asole, Haresh Bharote, Anil Venkatachalam","doi":"10.4103/aian.aian_1070_24","DOIUrl":"10.4103/aian.aian_1070_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"476-478"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal Systolic Blood Pressure Control After Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis.","authors":"Baikuntha Panigrahi, Rohit Bhatia, Partha Haldar, Risha Sarkar, Imnameren Longkumer","doi":"10.4103/aian.aian_1087_24","DOIUrl":"10.4103/aian.aian_1087_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>The optimal systolic blood pressure (SBP) control after endovascular thrombectomy (EVT) is unclear. This study aimed to determine whether intensive SBP control (<140 mmHg) within 24 h post-EVT, compared to conventional management (<180 mmHg), leads to a better functional outcome, defined as a modified Rankin Scale (mRS) score of 0-2 at 90 days.</p><p><strong>Methods: </strong>Following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, we searched databases (PubMed, Scopus, EMBASE, Google Scholar, Web of Science) for English language articles up to March 15, 2024. We included randomized controlled trials (RCTs) and observational studies comparing intensive versus conventional SBP control up to 24 h post-EVT. Studies without separate primary outcome data and case series/reports were excluded. The primary outcome was functional independence (mRS 0-2 at 90 days).</p><p><strong>Results: </strong>Twelve studies (n = 5152 patients; five RCTs and seven observational studies) were included, and a primary analysis of the RCTs, along with a secondary exploratory analysis of the observational studies were conducted. The analysis of RCTs favored conventional control for the primary outcome (risk ratio [RR]- 0.81; 95% confidence interval [CI]- 0.73-0.90; P < 0.0001). Mortality rates (RR- 1.14, 95% CI- 0.89-1.45; P = 0.29) and the risk of symptomatic intracranial hemorrhage (RR- 1.10, 95% CI- 0.77-1.58; P = 0.60) were similar in both groups. The secondary exploratory analysis of observational data favored the intensive arm for the primary outcome (RR- 1.28, 95% CI- 1.17-1.41; P < 0.00001).</p><p><strong>Conclusions: </strong>Our primary analysis of RCTs showed that intensive control was associated with poorer functional outcomes, with no significant impact on mortality rate or the risk of symptomatic intracranial hemorrhage. Although observational studies suggested better outcomes with intensive control, we recommend conventional management based on Level 1 evidence from RCTs.PROSPERO Registration no - CRD42023463173.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"323-332"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usefulness of 131 I-MIBG Myocardial Scintigraphy in a Case of Pure Autonomic Failure - First Report in the Literature.","authors":"Ramkumar Sugumaran, Ragavendar Bhuvaneswaran, Jayaram Saibaba, Sunil K Narayan, Sai Kishore Sundarraj, Nandini Pandit","doi":"10.4103/aian.aian_990_24","DOIUrl":"10.4103/aian.aian_990_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"445-447"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Venous Thrombosis: Selected Persisting Areas of Uncertainty.","authors":"Thalia S Field, Sanjith Aaron, Sarvani Chetty, Alejandro Fuerte-Hortigon, Mays Garah, Yundi Wang","doi":"10.4103/aian.aian_162_25","DOIUrl":"10.4103/aian.aian_162_25","url":null,"abstract":"<p><strong>Abstract: </strong>Although a rare stroke type, recent large collaborative efforts have further improved the state of knowledge regarding management of cerebral venous thrombosis (CVT). However, several areas of uncertainty remain. In this review, we focus on existing evidence and priorities for future research in some select areas in the acute management and longer-term follow-up of CVT: the role of endovascular therapy, management of CVT associated with head and neck infection, management of CVT associated with head trauma, monitoring for papilledema and vision loss, and the role of prophylactic antiseizure medication.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"307-313"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Bloomy Rind on Cheese Sign\" - A Radiological Biomarker of Leptomeningeal Metastasis.","authors":"Reshma Sultana Shaik, Sireesha Yareeda, Srikanth Reddy, Madhur Kumar Srivastava, Megha S Uppin, Praneetha Sagi","doi":"10.4103/aian.aian_971_24","DOIUrl":"10.4103/aian.aian_971_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"432-434"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Prof. Jose Berciano's Letter to the Editor on \"Intravenous Methylprednisolone in Guillain-Barré Syndrome: The Way Forward?\"","authors":"Kameshwar Prasad","doi":"10.4103/aian.aian_476_25","DOIUrl":"10.4103/aian.aian_476_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"457-458"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}