Annals of Indian Academy of Neurology最新文献_第9页

Occipital Localization of Electrocardiographic Artifacts in Pediatric Electroencephalograms: A Novel Observation and Implications. 小儿脑电图中心电图伪影的枕骨定位：新的观察结果和意义。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-21 DOI: 10.4103/aian.aian_1116_23

Gosala R K Sarma, Sowmyashree M Kaku, Manjula W James, Ashok Mysore

引用次数: 0

Prevalence and Severity of Central Sensitization in Post-Polio Syndrome: Associations with Clinical Measures and Quality of Life. 脊髓灰质炎后综合征中枢过敏的患病率和严重程度：与临床指标和生活质量的关系

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-22 DOI: 10.4103/aian.aian_1040_23

Arzu Y On, Emre Latifoglou, Ece Çınar, Göksel Tanıgör

{"title":"Prevalence and Severity of Central Sensitization in Post-Polio Syndrome: Associations with Clinical Measures and Quality of Life.","authors":"Arzu Y On, Emre Latifoglou, Ece Çınar, Göksel Tanıgör","doi":"10.4103/aian.aian_1040_23","DOIUrl":"10.4103/aian.aian_1040_23","url":null,"abstract":"Objectives: To investigate the presence and severity of central sensitization (CS) and its associations with clinical measures and quality of life (QoL) in individuals with a history of paralytic poliomyelitis with and without post-polio syndrome (PPS).Methods: In this cross-sectional study, we included 98 individuals with a history of poliomyelitis, in whom 82 (83.6%) met the criteria of PPS. We used CS Inventory (CSI) to evaluate the presence and severity of CS. We evaluated the severity of fatigue, pain, polio-related impairments, and QoL using a Numerical Rating Scale in addition to Fatigue Severity Scale, Self-reported Impairments in Persons with late effects of Polio rating scale (SIPP), and Nottingham Health Profile (NHP).Results: CS was present in 52.4% of patients with PPS, of which 63% are classified as severe to extreme. Those with CS reported more severe symptoms, more polio-related impairments, and worse QoL than those without CS. Severity of CS showed significant positive correlations with severity of fatigue, pain, SIPP, and NHP scales in those with PPS. CSI did not indicate CS in any of those without PPS.Conclusion: CS was present in more than half of the individuals with PPS and correlated with more severe pain, fatigue, and more polio-related impairments, in addition to poorer QoL. These findings suggest that CS may contribute to the clinical picture in a subgroup of individuals with PPS. Thus, identification and appropriate management of CS patients may potentially help alleviate their symptoms and improve their QoL.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141439996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serial MRI Changes in Febrile Infection-Related Epilepsy Syndrome (FIRES): A Clinical and Radiologic Exploration. 发热感染相关癫痫综合征（FIRES）的磁共振成像序列变化：临床与放射学探索。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-20 DOI: 10.4103/aian.aian_823_23

Savith Kumar, Anvesh Apkari, Suryanarayan Sharma

引用次数: 0

Characterization of Event Related Desynchronization in Chronic Stroke Using Motor Imagery Based Brain Computer Interface for Upper Limb Rehabilitation. 利用基于运动想象的脑机接口进行上肢康复训练，描述慢性中风患者与事件相关的非同步化特征

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-05 DOI: 10.4103/aian.aian_1056_23

Sagila K Gangadharan, Subasree Ramakrishnan, Andrew Paek, Akshay Ravindran, Vinod A Prasad, Jose L Contreras Vidal

{"title":"Characterization of Event Related Desynchronization in Chronic Stroke Using Motor Imagery Based Brain Computer Interface for Upper Limb Rehabilitation.","authors":"Sagila K Gangadharan, Subasree Ramakrishnan, Andrew Paek, Akshay Ravindran, Vinod A Prasad, Jose L Contreras Vidal","doi":"10.4103/aian.aian_1056_23","DOIUrl":"10.4103/aian.aian_1056_23","url":null,"abstract":"Objective: Motor imagery-based brain-computer interface (MI-BCI) is a promising novel mode of stroke rehabilitation. The current study aims to investigate the feasibility of MI-BCI in upper limb rehabilitation of chronic stroke survivors and also to study the early event-related desynchronization after MI-BCI intervention.Methods: Changes in the characteristics of sensorimotor rhythm modulations in response to a short brain-computer interface (BCI) intervention for upper limb rehabilitation of stroke-disabled hand and normal hand were examined. The participants were trained to modulate their brain rhythms through motor imagery or execution during calibration, and they played a virtual marble game during the feedback session, where the movement of the marble was controlled by their sensorimotor rhythm.Results: Ipsilesional and contralesional activities were observed in the brain during the upper limb rehabilitation using BCI intervention. All the participants were able to successfully control the position of the virtual marble using their sensorimotor rhythm.Conclusions: The preliminary results support the feasibility of BCI in upper limb rehabilitation and unveil the capability of MI-BCI as a promising medical intervention. This study provides a strong platform for clinicians to build upon new strategies for stroke rehabilitation by integrating MI-BCI with various therapeutic options to induce neural plasticity and recovery.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling Distinctive MRI Characteristics in the Diagnosis of GFAP Astrocytopathy: A Rare Autoimmune Neuroinflammatory Disorder. 揭示诊断 GFAP 星形细胞病的独特 MRI 特征：一种罕见的自身免疫性神经炎性疾病

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-10 DOI: 10.4103/aian.aian_1134_23

Bheru D Charan, Shikha Priya, Vinay Goel, Pinky Chhatarpal, Savyasachi Jain, Anu Gupta, Ajay Garg

引用次数: 0

Navigating the Uncharted: A Rare Case of Ocular Flutter and Intermittent Jaw Movements in a Case of Chronic Lymphoid Leukemia. 探索未知领域：慢性淋巴细胞白血病患者眼球震颤和间歇性下颌运动的罕见病例。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-20 DOI: 10.4103/aian.aian_22_24

Kunal Arora, Amit S Singh, Rajeev Bedi, Ketan Dang, Arunjeet Kaur

引用次数: 0

Understanding Psychosocial Functioning, Caregiver Burden, and Neuropalliative Care in Parkinson's Disease - A Mixed-Methods Study. 了解帕金森病患者的社会心理功能、护理者负担和神经姑息治疗--一项混合方法研究。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-21 DOI: 10.4103/aian.aian_83_24

Prerna Sharma, Upasana Baruah, Akanksha Yadav, Suman Kushwaha, Rajinder K Dhamija

{"title":"Understanding Psychosocial Functioning, Caregiver Burden, and Neuropalliative Care in Parkinson's Disease - A Mixed-Methods Study.","authors":"Prerna Sharma, Upasana Baruah, Akanksha Yadav, Suman Kushwaha, Rajinder K Dhamija","doi":"10.4103/aian.aian_83_24","DOIUrl":"10.4103/aian.aian_83_24","url":null,"abstract":"Background: Despite advancements in treatment, patients with Parkinson's disease (PD) experience a range of symptoms that affect their quality of life. There is a need to integrate neuropalliative care into standard care. The aim of the study is to understand the psychosocial functioning in persons with PD and explore their caregivers' burden.Methods: The study utilizes a mixed-methods design where 50 patient-caregiver dyads attending the outpatient services of the movement disorder clinic at a tertiary care hospital were measured on psychosocial functioning and caregiver burden and palliative care outcomes for a period of 6 months. Focus group discussions were conducted with 18 patient-caregiver dyads to understand the needs of palliative care.Results: It was found that caregiver burden was positively correlated with palliative care outcomes scores of patients ( r = 0.586) and caregivers ( r = 0.675) and psychosocial functioning was positively correlated with palliative care outcomes of patients ( r = 0.708). The psychosocial functioning score was higher among female patients (indicating worse functioning) than males, and female caregivers experienced significantly higher caregiver burden. The qualitative findings reveal that there is a substantial gap in awareness about palliative care, lack of information, presence of stigmatizing beliefs, and lack of adequate accessibility to palliative facilities.Conclusion: The study lays the foundation for future PD neuropalliative care research, guiding interventions, and exploration of regional variations in PD experiences in India. There is a need to address caregiver burden in PD in India.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical Presentation of Seronegative Paraneoplastic Lambert-Eaton Myasthenic Syndrome with Cerebellar Ataxia. 血清阴性副肿瘤性兰伯特-伊顿肌萎缩综合征伴小脑共济失调的非典型表现。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-20 DOI: 10.4103/aian.aian_979_23

Shalesh Rohatgi, Siddharth Nimal, Satish Nirhale, Prajwal Rao, Pravin Naphade, Prashant Dubey, Advait Gitay, Pranit Khandait, Khusboo Hatekar, Salil Gundewar

引用次数: 0

Getting to the Core of Stroke. 了解中风的核心。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-21 DOI: 10.4103/aian.aian_455_24

Abhishek Anand, Rohit Bhatia

引用次数: 0

Determining Effectiveness of "Off-Label Therapies" for Multiple Sclerosis in a Real-World Setting. 在真实世界中确定 "标示外疗法 "对多发性硬化症的疗效。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-05-01 Epub Date: 2024-06-24 DOI: 10.4103/aian.aian_114_24

Lekha Pandit, Sharik Mustafa, Akshatha Sudhir, Puneeth Malapur, Anitha D'Cunha

{"title":"Determining Effectiveness of \"Off-Label Therapies\" for Multiple Sclerosis in a Real-World Setting.","authors":"Lekha Pandit, Sharik Mustafa, Akshatha Sudhir, Puneeth Malapur, Anitha D'Cunha","doi":"10.4103/aian.aian_114_24","DOIUrl":"10.4103/aian.aian_114_24","url":null,"abstract":"Objective: To determine the factors, if any, that are associated with the efficacy of \"off-label therapies\" (OLTs) for multiple sclerosis (MS).Methods: Consecutive patients (N = 174) with relapsing-remitting MS (RRMS) or secondary progressive MS (SPMS) with relapses, on OLTs with a generic formulation of azathioprine, mycophenolate mofetil, or rituximab biosimilar for ≥2 years were included. Annualized relapse rate (ARR) and expanded disability status score (EDSS) 1 year before and ≥2 years after starting OLTs were recorded. Optical coherence tomography (OCT) was done at baseline and at the end of the study.Results: During a median period of 4.1 years (2.4-24), ARR reduced in all (P < 0.0001) and EDSS improved in RRMS (P < 0.0001) patients but not in SPMS (P < 0.31) patients. Good responders were those who had RRMS (P = 0.001, odds ratio [OR] 0.04, 95% confidence interval [CI] 0.01-0.15), female gender (P 0.008, OR 6.67, 95% CI 1.7-26.8), and had early access to OLT (P = 0.006, OR 1.2, 95% CI 1.05-1.40). Baseline peripapillary retinal nerve fiber layer thickness identified the risk of conversion to SPMS (P < 0.01, OR 1.03; 95% CI 1.01-1.06).Conclusions: This limited prospective study suggests that early identification of patients who could potentially respond to unconventional but accessible therapies may be valuable in the treatment of MS, particularly in resource-poor regions.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11232820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141442060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0