Annals of Indian Academy of Neurology最新文献_第3页

Quantification and Clinical Correlation of Posterior Cranial Fossa Cerebrospinal Fluid Volume in Primary Hemifacial Spasm Using Magnetic Resonance Imaging. 利用磁共振成像对原发性面肌痉挛患者颅后窝脑脊液容量进行量化并与临床相关性分析

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-07-12 DOI: 10.4103/aian.aian_199_24

Dds Anudeep, Karthik Kulanthaivelu, Vikram V Holla, Nitish Kamble, Ravi Yadav, Pramod Kumar Pal, Rohan R Mahale

{"title":"Quantification and Clinical Correlation of Posterior Cranial Fossa Cerebrospinal Fluid Volume in Primary Hemifacial Spasm Using Magnetic Resonance Imaging.","authors":"Dds Anudeep, Karthik Kulanthaivelu, Vikram V Holla, Nitish Kamble, Ravi Yadav, Pramod Kumar Pal, Rohan R Mahale","doi":"10.4103/aian.aian_199_24","DOIUrl":"10.4103/aian.aian_199_24","url":null,"abstract":"Background and objective: Primary hemifacial spasm (HFS) is caused by neurovascular conflict (NVC) at the root entry zone of the facial nerve. Whether reduction of posterior cranial fossa (PCF) cerebrospinal fluid (CSF) volume is a risk factor for HFS is not clear. The study aims at the radiologic assessment of PCF CSF volume and its clinical correlation.Methods: A cross-sectional, hospital-based, case-control study was conducted, in which 50 cases of primary HFS and 50 age- and sex-matched controls were recruited. PCF CSF volume was quantified in 3-T brain magnetic resonance imaging.Results: The mean age at presentation of cases was 50.7 ± 10.7 years (42-69 years) and controls was 52.4 ± 8.7 years (45-68 years). The mean duration of symptoms was 3.5 ± 1.3 years (1.5-8 years). About 52% of patients had grade 2 (mild) severity of HFS. The mean PCF CSF volume of patients was 13,725.1 ± 909.5 mm 3 and controls was 14,458.5 ± 973.5 mm 3 ( P < 0.001). The mean PCF CSF volume of females with HFS was 13,714.8 ± 852.5 mm 3 and female controls was 14,521.8 ± 973.5 mm 3 ( P = 0.006). PCF CSF volume was significantly associated with the presence of HFS ( P = 0.007), the severity of HFS ( P < 0.001), and the presence of NVC ( P = 0.02).Conclusion: PCF CSF volume was lesser in HFS patients and was associated with the presence of HFS, the severity of HFS, and the presence of NVC. Females with HFS had smaller PCF CSF volume. Small PCF CSF volume is a risk factor for HFS, particularly in females with HFS.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Language Function in Bengali-Speaking Population with Motor Neuron Disease. 孟加拉语运动神经元疾病患者的语言功能研究

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-08 DOI: 10.4103/aian.aian_44_24

Siladitya Das, Debal Laha, Prasenjit Sengupta

{"title":"Study of Language Function in Bengali-Speaking Population with Motor Neuron Disease.","authors":"Siladitya Das, Debal Laha, Prasenjit Sengupta","doi":"10.4103/aian.aian_44_24","DOIUrl":"10.4103/aian.aian_44_24","url":null,"abstract":"Background: Motor neuron diseases (MNDs) have been traditionally considered to spare cognition. But recent findings show that multiple domains of cognition including language can be involved in MND patients. Most studies on language patterns of MND patients were conducted in Western nations, but data on Indian population is limited. This study is an attempt to explore the language functions of Bengali-speaking MND patients from this part of eastern India.Objective: To determine the prevalence and nature of language dysfunction in MND patients.Materials and methods: A single-center, hospital-based, observational, cross-sectional study. The Bengali adaptation of the Western Aphasia Battery was administered to 50 cases diagnosed with MND, attending a tertiary care hospital consecutively over a 1-year period, and fulfilling the inclusion and exclusion criteria for the study. Descriptive and inferential statistics were used for expressing results.Results: Eighteen percent of cases showed impairments in spontaneous speech. Fluency was impaired in 72%, and 22% cases showed impaired naming. Moreover, 20% and 26% of cases were impaired in repetition and comprehension, respectively. Reading and writing was impaired in 16% and 26% of cases, respectively. Significant difference was found in the primary language skill scores and aphasia quotient across age groups, while no significant difference was found in these scores across education status.Conclusions: This study describes the language profiles of Bengali-speaking MND patients from eastern India, and the findings are similar to previous research works, which have shown morpho-syntactic, lexical-semantic, and phonological errors in language function.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palatal Tremor, Periocular and Perioral Myokymia, and Pseudoathetosis in a Patient with Whipple's Disease. 一名威普尔氏病患者的腭震颤、眼周和口周肌强直以及假性肢体瘫痪。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-07-18 DOI: 10.4103/aian.aian_206_24

Vaidehi Jha, Archita Makharia, Divyani Garg, Ayush Agarwal, Divya M Radhakrishnan, Awadh Kishor Pandit, Achal Kumar Srivastava

引用次数: 0

Genetic Analysis of De Novo Variants in KMT2A mixed-lineage leukemia Identified in a Family of Wiedermann-Steiner Syndromes. 在一个 Wiedermann-Steiner 综合征家族中发现的 KMT2A 混系白血病新变异基因分析

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-08 DOI: 10.4103/aian.aian_108_24

Min Cao, Tang Dan, Xiaocheng Nie, Biao Tang, Lan Zeng, Guanghuan Pi, Ai Chen, Hongquan Luo, Shuyao Zhu

引用次数: 0

Contrast-Induced Encephalopathy: A Case Series Analysis. 对比度诱发脑病：病例系列分析。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-22 DOI: 10.4103/aian.aian_548_24

Alexander Stebner, Salome Bosshart, Nicolin Hainc, Nathalie Nierobisch, Marialuisa Zedde, Rosario Pascarella, Mayank Goyal, Johanna Ospel

{"title":"Contrast-Induced Encephalopathy: A Case Series Analysis.","authors":"Alexander Stebner, Salome Bosshart, Nicolin Hainc, Nathalie Nierobisch, Marialuisa Zedde, Rosario Pascarella, Mayank Goyal, Johanna Ospel","doi":"10.4103/aian.aian_548_24","DOIUrl":"10.4103/aian.aian_548_24","url":null,"abstract":"Background: Contrast-induced encephalopathy (CIE) is a rare adverse event linked to intravascular use of iodine-containing contrast media. The prevalence of CIE could increase in the future due to growing numbers of endovascular procedures. We provide insights from a case series of 7 patients.Methods: Cases from 3 centers were collected based on existing academic collaborations, and key factors were extracted to illustrate development and management of CIE.Results: In our retrospective case-series analysis of 7 cases from 3 countries, affected patients had an equal distribution of sex (4 women, 3 men) and a median age of 75 (IQR 63-77). Common risk factors included hypertension (5/7), hyperlipidemia (5/7), previous stroke (3/7), and type 2 diabetes (3/7). CIE developed in 3 cases after endovascular thrombectomy (EVT) for stroke, in 2 cases after aneurysm treatment, in 1 case after cardiac catheterization, and in 1 case after diagnostic computed tomography (CT) angiography without an endovascular procedure. The median procedure time was 48 min (IQR 40-81). All patients received non-ionic, low-osmolar contrast agents with volumes ranging from 100-300 ml. Symptom onset was close to contrast administration, with stroke-like neurological deficits being most common (4/7). Prednisolone was the most frequently used medication to treat the symptoms (4/7). Symptom resolution occurred in 4 out of 7 patients within two to several days, and 1 patient died, but without clear connection to CIE.Conclusion: CIE is a rare and possibly underrecognized condition, but fortunately, with a favorable outcome in most cases.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142085945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hirayama Disease: Neutral and Flexion Magnetic Resonance Imaging Manifestations and Single Tertiary Care Center Analysis on 3T Scanner. 平山症：中性和挠性磁共振成像表现及单个三级医疗中心 3T 扫描仪分析。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-21 DOI: 10.4103/aian.aian_236_24

Pankaj Kaira, Vaanika Kaira, Sameer R Verma, Sunil Kumar

{"title":"Hirayama Disease: Neutral and Flexion Magnetic Resonance Imaging Manifestations and Single Tertiary Care Center Analysis on 3T Scanner.","authors":"Pankaj Kaira, Vaanika Kaira, Sameer R Verma, Sunil Kumar","doi":"10.4103/aian.aian_236_24","DOIUrl":"10.4103/aian.aian_236_24","url":null,"abstract":"Background: Hirayama disease (HD) is a rare benign type of cervical cord myelopathy occurring commonly in young males as unilateral or bilateral asymmetrical amyotrophy of the hand and forearm muscles in C8-T1 distribution. Magnetic resonance imaging (MRI) is the best technique for the evaluation and imaging of this entity.Materials and methods: This is a retrospective review of cervical magnetic resonance images of patients that were taken for clinically suspected and diagnosed HD on 3T MRI in postcontrast neutral and flexion (30°-40°) positions from July 2019 to January 2024 at Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly.Results: Fourteen patients included in the study were males less than 34 years of age. MRI findings of cord atrophy in the lower cervical region/cervico-dorsal junction, abnormal cervical curvature, loss of attachment of the dorsal dural sac and subjacent laminae with anterior displacement, and a prominent intense enhancing posterior epidural space were observed in all 14 patients. The minimum anteroposterior cord diameters in the neutral and flexion positions were 2.9 and 2.8 mm, respectively (mean thickness of laminodural space on flexion - 5.2 mm). Other MRI findings showed variable representations.Conclusions: Flexion-position MRI has emerged as the gold standard for establishing and validating the diagnosis of HD in clinically suspected cases and should be an essential part of the protocol for the screening of clinically suspected cases of HD to aid in early treatment and therapeutic intervention. Complimentary newer sequences such as the Three-dimensional (3D)-Constructive interference in Steady State (CISS)/Fast Imaging Employing Steady-state Acquisition Cycled Phases (FIESTA-C) may reinforce better appreciation of epidural flow voids.","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Status of Tranexamic Acid in Hyperacute Treatment of Intracerebral Hemorrhage. 氨甲环酸在超急性脑出血治疗中的应用现状。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-23 DOI: 10.4103/aian.aian_435_24

Atul Philips, Jeyaraj Durai Pandian

引用次数: 0

The Phenotypic Range of Mitochondrial Myopathies and Disorders is More Diverse Than Expected. 线粒体肌病和失调症的表型范围比预期的更为多样。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-06-10 DOI: 10.4103/aian.aian_76_24

Josef Finsterer

引用次数: 0

Horizontal Gaze Palsy with Progressive Scoliosis. 伴有进行性脊柱侧凸的水平凝视麻痹。

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI: 10.4103/aian.aian_7_24

Muhammed Shadique, Leema P Cornelius, Neeraj Elango, Jered Livingston

引用次数: 0

Spastic Paraparesis in Donnai-Barrow Syndrome: A Rare Case Report from India. 唐奈-巴罗综合征痉挛性瘫痪：来自印度的罕见病例报告

IF 1.9 4区医学

Annals of Indian Academy of Neurology Pub Date : 2024-07-01 Epub Date: 2024-08-20 DOI: 10.4103/aian.aian_962_23

Swati Parida, Nikhil A Kumar, Rameshwar N Chaurasia, Anand Kumar, Abhishek Pathak, Varun K Singh

引用次数: 0