Annals of Indian Academy of Neurology最新文献

筛选
英文 中文
Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention.
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-02-07 DOI: 10.4103/aian.aian_497_24
Agrata Sharma, Ayush Agarwal, Ajay Garg, Venugopalan Y Vishnu, N Nilima, Rohit Bhatia, Divyani Garg, Awadh K Pandit, Leve Joseph, Srujana Billa, Manmohan Singh, Ashish Suri, Shashank S Kale, Shailesh B Gaikwad, Mv Padma Srivastava
{"title":"Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention.","authors":"Agrata Sharma, Ayush Agarwal, Ajay Garg, Venugopalan Y Vishnu, N Nilima, Rohit Bhatia, Divyani Garg, Awadh K Pandit, Leve Joseph, Srujana Billa, Manmohan Singh, Ashish Suri, Shashank S Kale, Shailesh B Gaikwad, Mv Padma Srivastava","doi":"10.4103/aian.aian_497_24","DOIUrl":"https://doi.org/10.4103/aian.aian_497_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Uncertainty still exists regarding the benefit of surgery in the management of supratentorial spontaneous ICH (sICH), especially of the basal ganglia and thalamus. Studies have not shown the clinical benefit of early surgical management compared to best medical management plus delayed surgery, when necessary. Our aim was to compare the efficacy of different neurosurgical interventions with best medical management and best medical management alone.</p><p><strong>Methods: </strong>We conducted a single-center, retrospective study at a tertiary care center in India in sICH patients between January 2015 and December 2022. The primary outcome was functional disability evaluated by the modified Rankin Scale (mRS) at 3, 6, and 12 months. Time-to-event outcomes were compared using the Kaplan-Meier curve.</p><p><strong>Results: </strong>Among 2600 stroke patients screened, 661 had sICH. Median age was 55 years, and 250 patients (37.8%) underwent neurosurgical intervention. The most common intervention was craniotomy and hematoma evacuation. The median mRS at discharge and follow-up at 3, 6, and 12 months was lower in the conservatively managed group (4, 3, 3, and 3, respectively) compared to the surgical intervention group (5, 5, 5, 4, respectively). However, the ICH score at admission was lower in the conservatively managed group and after adjustment for ICH score, there was no statistically significant difference between the two. Among the interventions, patients undergoing decompression craniectomy had the best functional outcome.</p><p><strong>Conclusions: </strong>Neurosurgical intervention was not associated with better functional outcome when compared to conservative management.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptomatic Bevacizumab-Induced Cerebral Infarction Following Treatment for Radiation Necrosis. 放射线坏死治疗后贝伐珠单抗诱发的症状性脑梗塞。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-02-06 DOI: 10.4103/aian.aian_645_24
Boby V Maramattom
{"title":"Symptomatic Bevacizumab-Induced Cerebral Infarction Following Treatment for Radiation Necrosis.","authors":"Boby V Maramattom","doi":"10.4103/aian.aian_645_24","DOIUrl":"https://doi.org/10.4103/aian.aian_645_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurotoxicity of Calcineurin Inhibitors. 降钙素抑制剂的神经毒性
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-31 DOI: 10.4103/aian.aian_614_24
Aleksander Bajon, Jędrzej Sikora, Michal Siwek, Julia Wiecanowska, Miłosz Miedziaszczyk, Ilona Idasiak-Piechocka, Anna Mania
{"title":"Neurotoxicity of Calcineurin Inhibitors.","authors":"Aleksander Bajon, Jędrzej Sikora, Michal Siwek, Julia Wiecanowska, Miłosz Miedziaszczyk, Ilona Idasiak-Piechocka, Anna Mania","doi":"10.4103/aian.aian_614_24","DOIUrl":"https://doi.org/10.4103/aian.aian_614_24","url":null,"abstract":"<p><strong>Abstract: </strong>Cyclosporine and tacrolimus belong to the immunosuppressive drugs of the calcineurin inhibitors group. They are widely used in the treatment of patients after organ transplants. One of their complications is neurotoxicity, the mechanism of which is still not fully understood. The main risk factor for neurotoxicity is hypertension. The most common symptoms include muscle tremors, which are more common in the upper limbs, as well as migraine headaches and peripheral neuropathies. The diagnosis of neurotoxicity is based on imaging tests (magnetic resonance imaging being the most commonly used) and assessment of clinical symptoms. Preventive measures should be initiated as soon as possible to prevent permanent damage to the nerve tissue. The possible preventive methods include reduction of the dose of the administered drug, temporary or complete discontinuation of drugs, or conversion to another immunosuppressive drug. It is also essential to monitor the patient's condition, correct hypertension, electrolyte disturbances, and fight possible infections. So far, effective methods of preventing calcineurin inhibitor-induced neurotoxicity have not been demonstrated.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tardive Syndromes: A Challenging Multitude of Maladies.
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-29 DOI: 10.4103/aian.aian_657_24
Ranjot Kaur, Vaibhav Patil, Ayush Agarwal, Achal K Srivastava, Divyani Garg
{"title":"Tardive Syndromes: A Challenging Multitude of Maladies.","authors":"Ranjot Kaur, Vaibhav Patil, Ayush Agarwal, Achal K Srivastava, Divyani Garg","doi":"10.4103/aian.aian_657_24","DOIUrl":"https://doi.org/10.4103/aian.aian_657_24","url":null,"abstract":"<p><strong>Abstract: </strong>\"Tardive syndrome\" is an umbrella term for a group of drug-induced movement disorders associated with the prolonged use of mainly dopamine receptor blockers and also other medications. Early recognition followed by gradual withdrawal of the incriminating drug may lead to reversal, although not in all patients. Tardive syndromes are usually mixed movement disorders, with specific phenotypes, which may lead to severe disability. The pathophysiology remains incompletely understood. Treatment ranges from medical options, particularly dopamine-depleting agents and chemodenervation (botulinum toxin), to surgical options (deep brain stimulation and lesioning surgeries). Most studies that focused on treatment are limited by small patient numbers. Unfortunately, tardive syndromes often remain under-recognized in clinical practice. This article reviews the historical aspects, epidemiology and risk factors, pathophysiology, diagnostic criteria, clinical phenotypes, and management of tardive syndromes.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organizing Pneumonia and Immunomediated Colitis Associated with Ocrelizumab Treatment.
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-29 DOI: 10.4103/aian.aian_608_24
Daniel A García-Estévez, Coral Tejido-Sandoval, Montserrat Díaz-Gutiérrez, Clara González-Núñez, Elena Otero-Gutiérrez, Lidia Santos-López
{"title":"Organizing Pneumonia and Immunomediated Colitis Associated with Ocrelizumab Treatment.","authors":"Daniel A García-Estévez, Coral Tejido-Sandoval, Montserrat Díaz-Gutiérrez, Clara González-Núñez, Elena Otero-Gutiérrez, Lidia Santos-López","doi":"10.4103/aian.aian_608_24","DOIUrl":"https://doi.org/10.4103/aian.aian_608_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MOGAD and Mortality: A Rarity.
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-24 DOI: 10.4103/aian.aian_726_24
Uk Kandha Kumar, Pradeep K Gunasekaran, Ashna Kumar, Daisy Khera, Sarbesh Tiwari, Lokesh Saini
{"title":"MOGAD and Mortality: A Rarity.","authors":"Uk Kandha Kumar, Pradeep K Gunasekaran, Ashna Kumar, Daisy Khera, Sarbesh Tiwari, Lokesh Saini","doi":"10.4103/aian.aian_726_24","DOIUrl":"https://doi.org/10.4103/aian.aian_726_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal Chikungunya Encephalitis - A Mimic of Leukoencephalopathy.
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-24 DOI: 10.4103/aian.aian_806_24
Mahesh Kamate, Basavanagowda Thanuja, Sugata Mahapatra, Manisha Bhandankar, Virupaxi Hattiholi
{"title":"Neonatal Chikungunya Encephalitis - A Mimic of Leukoencephalopathy.","authors":"Mahesh Kamate, Basavanagowda Thanuja, Sugata Mahapatra, Manisha Bhandankar, Virupaxi Hattiholi","doi":"10.4103/aian.aian_806_24","DOIUrl":"https://doi.org/10.4103/aian.aian_806_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing Parkinson's Disease-Associated Pain in Native Patients with Malayalam Version of the King's Parkinson's Disease Pain Scale. 用马拉雅拉姆版的King’s帕金森病疼痛量表来表征本土患者帕金森病相关疼痛
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-18 DOI: 10.4103/aian.aian_701_24
Prabhu Attur Selvaraj, Asish Vijayaraghavan, Vineeth Radhakrishnan, Divya Kalikavil Puthenveedu, Gangadhara Sarma, Sankara P Sarma, Syam Krishnan
{"title":"Characterizing Parkinson's Disease-Associated Pain in Native Patients with Malayalam Version of the King's Parkinson's Disease Pain Scale.","authors":"Prabhu Attur Selvaraj, Asish Vijayaraghavan, Vineeth Radhakrishnan, Divya Kalikavil Puthenveedu, Gangadhara Sarma, Sankara P Sarma, Syam Krishnan","doi":"10.4103/aian.aian_701_24","DOIUrl":"https://doi.org/10.4103/aian.aian_701_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>Pain is an important non-motor symptom in Parkinson's disease (PD) and is often under-recognized. Pain is also a symptom frequently reported by non-PD elderly subjects. The King's Parkinson's Disease Pain Scale (KPPS) is a valid tool to characterize and quantify pain in PD and has been translated into several languages.</p><p><strong>Methods: </strong>We translated KPPS to Malayalam for native patients with PD and examined the pain characteristics in consecutive patients. Correlations with comprehensive disease-specific rating scales, including the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale (MDS-UPDRS) and the Non-Motor Symptoms Scale (NMSS), were explored. A group of age- and gender-matched subjects without PD were interviewed using KPPS to examine how the pain reported by the non-PD aging population is different from that in PD.</p><p><strong>Results: </strong>In this study, 82% of patients with PD reported at least one type of pain, compared to 31.3% of age- and gender-matched control subjects (P < 0.001). KPPS total scores (18.2 ± 14.0 vs. 1.8 ± 3.2; P < 0.001) and all the individual domain scores were significantly higher in patients. Pain scores correlated with age in control subjects (R = 0.46, P < 0.001), but not in patients; females reported more pain in both groups. Patients' pain scores were higher in the postural instability and gait difficulty subtype and showed significant correlations with MDS-UPDRS and NMSS scores.</p><p><strong>Conclusions: </strong>Pain is a prevalent symptom in PD and differs from the pain reported by a non-PD aging population. The Malayalam version of KPPS is a valid tool to characterize pain in native, Malayalam-speaking patients.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Isoniazid-Induced Cerebellitis in Diabetic Chronic Kidney Disease. 异烟肼致糖尿病慢性肾病小脑炎1例。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-16 DOI: 10.4103/aian.aian_741_24
Ramakrishna Ganapathiwar, Aumir Moin, Srinivas Nalloor, Shraddha Kedlaya K
{"title":"A Case of Isoniazid-Induced Cerebellitis in Diabetic Chronic Kidney Disease.","authors":"Ramakrishna Ganapathiwar, Aumir Moin, Srinivas Nalloor, Shraddha Kedlaya K","doi":"10.4103/aian.aian_741_24","DOIUrl":"https://doi.org/10.4103/aian.aian_741_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
All Tongue Fasciculations are Not Motor Neuron Disease. 并非所有的舌束动都是运动神经元疾病。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-01-10 DOI: 10.4103/aian.aian_690_24
Pushkar Pazhani, Saranya B Gomathy, Jayaram Saibaba, Manoj Manyem, Ramkumar Sugumaran, Sunil K Narayan
{"title":"All Tongue Fasciculations are Not Motor Neuron Disease.","authors":"Pushkar Pazhani, Saranya B Gomathy, Jayaram Saibaba, Manoj Manyem, Ramkumar Sugumaran, Sunil K Narayan","doi":"10.4103/aian.aian_690_24","DOIUrl":"https://doi.org/10.4103/aian.aian_690_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信