Polyneuropathy due to n-Hexane Intoxication - A Case Series.

IF 1.9 4区医学 Q3 CLINICAL NEUROLOGY

Annals of Indian Academy of Neurology Pub Date : 2025-05-09 DOI:10.4103/aian.aian_39_25

Khichar P Shubhakaran, Pradeep Lalwani, Nidhi Yadav

引用次数: 0

Abstract

Abstract: n-Hexane, a volatile organic chemical, is notorious for its neurotoxicity in occupational settings. We present four patients working in a needle manufacturing factory who presented with polyneuropathy after exposure to n-hexane by inhalation. Cerebrospinal fluid showed albuminocytological dissociation. Nerve conduction study (NCV) showed primary demyelination with secondary axonal polyneuropathy. Excluding the other possible causes, the diagnosis of n-hexane neuropathy was kept. Patients were managed with symptomatic treatment and showed marked improvement in 6-month follow-up.

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正己烷中毒引起的多神经病变-一个病例系列。

摘要：正己烷是一种挥发性有机化学物质，在职业环境中因其神经毒性而臭名昭著。我们报告了四名在针厂工作的患者，他们在吸入正己烷后出现了多神经病变。脑脊液显示白蛋白细胞分离。神经传导研究（NCV）显示原发性脱髓鞘伴继发性轴突多发性神经病。排除其他可能的原因，保留正己烷神经病的诊断。患者给予对症治疗，随访6个月，症状明显改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Indian Academy of Neurology Nervous System Diseases-

CiteScore

2.20

自引率

11.80%

发文量

293

审稿时长

29 weeks

期刊介绍： The journal has a clinical foundation and has been utilized most by clinical neurologists for improving the practice of neurology. While the focus is on neurology in India, the journal publishes manuscripts of high value from all parts of the world. Journal publishes reviews of various types, original articles, short communications, interesting images and case reports. The journal respects the scientific submission of its authors and believes in following an expeditious double-blind peer review process and endeavors to complete the review process within scheduled time frame. A significant effort from the author and the journal perhaps enables to strike an equilibrium to meet the professional expectations of the peers in the world of scientific publication. AIAN believes in safeguarding the privacy rights of human subjects. In order to comply with it, the journal instructs all authors when uploading the manuscript to also add the ethical clearance (human/animals)/ informed consent of subject in the manuscript. This applies to the study/case report that involves animal/human subjects/human specimens e.g. extracted tooth part/soft tissue for biopsy/in vitro analysis.