Annals of Indian Academy of Neurology最新文献

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Detection of Medium Vessel Occlusions (MeVOs) using Velocity-Encoded Vessel Maps in Selection and Endovascular Treatment of Double MeVO - A Case Report. 用速度编码血管图检测中血管闭塞(MeVOs)在双MeVOs的选择和血管内治疗中的应用- 1例报告。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-06-04 DOI: 10.4103/aian.aian_1115_24
Santhosh Ks Annayappa, Johanna M Ospel, Mayank Goyal, Nishita Singh, Nima Kashani
{"title":"Detection of Medium Vessel Occlusions (MeVOs) using Velocity-Encoded Vessel Maps in Selection and Endovascular Treatment of Double MeVO - A Case Report.","authors":"Santhosh Ks Annayappa, Johanna M Ospel, Mayank Goyal, Nishita Singh, Nima Kashani","doi":"10.4103/aian.aian_1115_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1115_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intersection of Autoimmunity: NMDA Positivity, Hypertrophic Pachymeningitis, and Primary CNS Angiitis in a Single Patient - A Diagnostic Challenge. 自身免疫的交叉:NMDA阳性,增生性厚性脑膜炎和原发性中枢神经系统脉管炎在一个单一的病人-诊断的挑战。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-30 DOI: 10.4103/aian.aian_147_25
Ravi P Singh, S Rima, Seetam Kumar, Parth Lalaji, Karthik Kulanthaivelu, Anita Mahadevan, T C Yasha, Girish B Kulkarni, Subasree Ramakrishnan, Ajay Asranna, Raghavendra Kenchiah
{"title":"Intersection of Autoimmunity: NMDA Positivity, Hypertrophic Pachymeningitis, and Primary CNS Angiitis in a Single Patient - A Diagnostic Challenge.","authors":"Ravi P Singh, S Rima, Seetam Kumar, Parth Lalaji, Karthik Kulanthaivelu, Anita Mahadevan, T C Yasha, Girish B Kulkarni, Subasree Ramakrishnan, Ajay Asranna, Raghavendra Kenchiah","doi":"10.4103/aian.aian_147_25","DOIUrl":"https://doi.org/10.4103/aian.aian_147_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare NF140-Positive Nodopathy Masquerading as Fulminant Guillain-Barré Syndrome: A Diagnostic Challenge. 伪装成暴发性吉兰-巴勒综合征的罕见nf140阳性病理:诊断挑战。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-30 DOI: 10.4103/aian.aian_249_25
Manu Vincent, Aswin Mathew Thomas, B Subitha
{"title":"Rare NF140-Positive Nodopathy Masquerading as Fulminant Guillain-Barré Syndrome: A Diagnostic Challenge.","authors":"Manu Vincent, Aswin Mathew Thomas, B Subitha","doi":"10.4103/aian.aian_249_25","DOIUrl":"https://doi.org/10.4103/aian.aian_249_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Restless Legs Syndrome in Patients Who Underwent Percutaneous Coronary Intervention in a Tertiary Care Hospital: A Cross-Sectional Study. 在三级医院接受经皮冠状动脉介入治疗的患者中不宁腿综合征的患病率:一项横断面研究。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-26 DOI: 10.4103/aian.aian_59_25
Anupama Gupta, Sriloy Mohanty, Varun Chhabra, Asmita Shukla, Partha Haldar, Rohit Bhatia, Gautam Sharma
{"title":"Prevalence of Restless Legs Syndrome in Patients Who Underwent Percutaneous Coronary Intervention in a Tertiary Care Hospital: A Cross-Sectional Study.","authors":"Anupama Gupta, Sriloy Mohanty, Varun Chhabra, Asmita Shukla, Partha Haldar, Rohit Bhatia, Gautam Sharma","doi":"10.4103/aian.aian_59_25","DOIUrl":"https://doi.org/10.4103/aian.aian_59_25","url":null,"abstract":"<p><strong>Background and objectives: </strong>Restless legs syndrome (RLS) is a risk for cardiovascular diseases and increases the risk of adverse cardiovascular outcomes following percutaneous coronary intervention (PCI). We aimed to determine the prevalence of RLS and its associated factors among coronary artery disease (CAD) patients undergoing PCI.</p><p><strong>Methods: </strong>This was a cross-sectional study conducted among CAD patients undergoing PCI at a tertiary care institute in India. All study participants underwent a detailed evaluation of RLS symptoms. Clinical and sleep evaluations were done through a prestructured questionnaire, Pittsburgh Sleep Quality Index, Berlin Questionnaire, and Epworth Sleepiness Scale. RLS was diagnosed according to the International Classification of Sleep Disorders-3rd edition. The symptoms and severity were characterized by using the All India Institute of Medical Sciences (AIIMS) RLS Questionnaire for Indian Patients and the International Restless Legs Syndrome Study Group (IRLSSG) rating scale.</p><p><strong>Results: </strong>Of 116 post-PCI study participants, with a mean age of 51.9 ± 8.5 years and in whom males constituted 92.5%, 25 (21.6%, 95% confidence interval = 14-30) patients had RLS. The prevalence of RLS was significantly higher among those with poor sleep quality (27.5% vs. 8.33%, P = 0.02). Among patients with RLS, the mean (standard deviation [SD]) age of onset of symptoms was 48.5 (10.2) years, and its median (interquartile range) duration was 24 (8-42) months. Mean (SD) IRLSSG score was 17.2 ± 7.3. Four (16%) patients had mild RLS, 14 (56%) had moderate RLS, six (24%) had severe RLS, and one (4%) had very severe RLS.</p><p><strong>Conclusions: </strong>One in five patients with PCI had RLS. Identification and optimal treatment of RLS in these patients could improve their quality of life.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144140993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Anti-MOG Antibody-Associated Disease (MOGAD) with Coexisting Myasthenia Gravis: A Rare Association. 小儿抗mog抗体相关疾病(MOGAD)与并存重症肌无力:罕见的关联
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-21 DOI: 10.4103/aian.aian_1019_24
Saheli Roy, Nishigandha S Joshi, Basit Ali, Vrajesh Udani
{"title":"Pediatric Anti-MOG Antibody-Associated Disease (MOGAD) with Coexisting Myasthenia Gravis: A Rare Association.","authors":"Saheli Roy, Nishigandha S Joshi, Basit Ali, Vrajesh Udani","doi":"10.4103/aian.aian_1019_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1019_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Educational and Socioeconomic Correlates of Stroke Risk Behaviors: Findings from the SPRINT INDIA Trial. 卒中风险行为的教育和社会经济相关性:来自SPRINT印度试验的发现。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-19 DOI: 10.4103/aian.aian_933_24
Shweta Jain Verma, Gurnoor Kaur, Arya Devi, Deepti Arora, Aneesh Dhasan, P N Sylaja, Dheeraj Khurana, Vijaya Pamidimukkala, Biman Kanti Ray, Vivek Nambiar, Sanjith Aaron, Gaurav Mittal, Sundarachary Nagarjunakonda, Aparna R Pai, Sankar Prasad Gorthi, Somasundaram Kumaravelu, Yerasu Muralidhar Reddy, Sunil Narayan, Nomal Chandra Borah, Rupjyoti Das, Girish Baburao Kulkarni, Vikram Huded, Thomas Mathew, Mv Padma Srivastava, Rohit Bhatia, Pawan Kumar Ojha, Jayanta Roy, Sherly Mary Abraham, Anand Girish Vaishnav, Arvind Sharma, Sheikh Jabeen, Abhishek Pathak, Sanjeev Kumar Bhoi, Sudhir Sharma, Sulena Sulena, Aralikatte Onkarappa Saroja, Neetu Ramrakhiani, Madhusudhan Byadarahalli Kempegowda, Mahesh Kate, Tina George, Ivy Sebastian, Meenakshi Sharma, Rupinder Dhaliwal, Rahul Huilgol, Jeyaraj D Pandian
{"title":"Educational and Socioeconomic Correlates of Stroke Risk Behaviors: Findings from the SPRINT INDIA Trial.","authors":"Shweta Jain Verma, Gurnoor Kaur, Arya Devi, Deepti Arora, Aneesh Dhasan, P N Sylaja, Dheeraj Khurana, Vijaya Pamidimukkala, Biman Kanti Ray, Vivek Nambiar, Sanjith Aaron, Gaurav Mittal, Sundarachary Nagarjunakonda, Aparna R Pai, Sankar Prasad Gorthi, Somasundaram Kumaravelu, Yerasu Muralidhar Reddy, Sunil Narayan, Nomal Chandra Borah, Rupjyoti Das, Girish Baburao Kulkarni, Vikram Huded, Thomas Mathew, Mv Padma Srivastava, Rohit Bhatia, Pawan Kumar Ojha, Jayanta Roy, Sherly Mary Abraham, Anand Girish Vaishnav, Arvind Sharma, Sheikh Jabeen, Abhishek Pathak, Sanjeev Kumar Bhoi, Sudhir Sharma, Sulena Sulena, Aralikatte Onkarappa Saroja, Neetu Ramrakhiani, Madhusudhan Byadarahalli Kempegowda, Mahesh Kate, Tina George, Ivy Sebastian, Meenakshi Sharma, Rupinder Dhaliwal, Rahul Huilgol, Jeyaraj D Pandian","doi":"10.4103/aian.aian_933_24","DOIUrl":"https://doi.org/10.4103/aian.aian_933_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>Secondary Prevention by Structured Semi-Interactive Stroke Prevention Package in India (SPRINT INDIA) trial was a randomized control trial that enrolled 4298 stroke patients and administered educational interventions at 31 centers across India, with the aim to reduce recurrent stroke through increased stroke knowledge. This SPRINT INDIA trial post hoc study aims to investigate the incidence of recurrent stroke, high-risk transient ischemic attack (TIA), acute coronary syndrome (ACS), death, and lifestyle behavioral factors at 1 year. In addition, it examines the relationship between patients' baseline characteristics and education levels, risk factors, and outcomes and performs subgroup analysis within the intervention and control groups.</p><p><strong>Methods: </strong>Participants were randomly assigned (1:1) to either intervention or control group through computer-based randomization on web. Intervention included stroke prevention Short Message Service messages, short-duration videos, and printed workbooks. Baseline assessments captured demographic and educational data, classifying patients into three categories: no schooling, less than high school, and high school or above. Primary outcome was a composite of recurrent stroke, high-risk TIA, ACS, and mortality at 1 year. Chi-square tests and analysis of variance were used to evaluate educational disparities across various variables.</p><p><strong>Results: </strong>The intervention did not reduce primary outcomes at 1 year among patients with different educational levels. Higher educational group was associated with enhanced medication adherence (94.3% vs 85.4%; P < 0.001), increased physical activity (5497.91 ± 4117.7 vs 6169.91±4828.8; P < 0.001), lower triglyceride levels, and decreased engagement in behavioral risk factors like alcohol intake (5.1% vs 6.8%; P = 0.013) and tobacco use (smoked and chewed) (4% vs 7.9%; P < 0.001 and 5.8% vs 11.6%; P = 0.020).</p><p><strong>Conclusions: </strong>Personalized secondary stroke prevention, tailored to educational levels, is crucial for effective stroke management.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyneuropathy due to n-Hexane Intoxication - A Case Series. 正己烷中毒引起的多神经病变-一个病例系列。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-09 DOI: 10.4103/aian.aian_39_25
Khichar P Shubhakaran, Pradeep Lalwani, Nidhi Yadav
{"title":"Polyneuropathy due to n-Hexane Intoxication - A Case Series.","authors":"Khichar P Shubhakaran, Pradeep Lalwani, Nidhi Yadav","doi":"10.4103/aian.aian_39_25","DOIUrl":"https://doi.org/10.4103/aian.aian_39_25","url":null,"abstract":"<p><strong>Abstract: </strong>n-Hexane, a volatile organic chemical, is notorious for its neurotoxicity in occupational settings. We present four patients working in a needle manufacturing factory who presented with polyneuropathy after exposure to n-hexane by inhalation. Cerebrospinal fluid showed albuminocytological dissociation. Nerve conduction study (NCV) showed primary demyelination with secondary axonal polyneuropathy. Excluding the other possible causes, the diagnosis of n-hexane neuropathy was kept. Patients were managed with symptomatic treatment and showed marked improvement in 6-month follow-up.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Sketch of Parkinson's Disease in India. 印度帕金森病的基因图谱。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-07 DOI: 10.4103/aian.aian_1021_24
Suvorit S Bhowmick, Soaham D Desai
{"title":"Genetic Sketch of Parkinson's Disease in India.","authors":"Suvorit S Bhowmick, Soaham D Desai","doi":"10.4103/aian.aian_1021_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1021_24","url":null,"abstract":"<p><strong>Abstract: </strong>By the current estimates, India is likely to face an alarmingly high burden of Parkinson's disease (PD) in the next two decades. Untangling the pathophysiology of PD through genetic research is the key to precision medicine and prevention strategies. This narrative review serves dual purpose of recapitulating phenomenology of monogenic diseases presenting with parkinsonism and synthesizing knowledge on PD genetics gained through research in India over the past two decades. Recent studies have detected rare genetic variants in 15%-20% of the early-onset PD patients in India. Due to lack of segregation analysis and functional validation, a vast majority of these remain as variants of uncertain significance. Nevertheless, several potentially pathogenic variants detected in the Indian PD patients are not yet cited in the global genetic databases such as Movement Disorder Society Genetic mutation database. Biallelic mutations (pathogenic single-nucleotide variants and copy number variants) in the PRKN gene account for 3%-5% of monogenic early-onset PD in the Indian population. About 2%-3% of the Indian EOPD patients carry pathogenic variants in the genes associated with atypical parkinsonism, such as PLA2G6, suggesting that initially, they may be indistinguishable from monogenic PD. Up to 10% of the PD patients in India carry heterozygous pathogenic variants in GBA1, a risk factor gene. Genetic research in India has several critical gaps, such as uneven geographic or ethnic representation, discrepancies in variant classification, and lack of large-scale genome-wide association studies. Sustained nationwide as well as international collaborative efforts are needed to bridge these gaps and foster translational science.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hidden Culprit: Middle Cerebral Artery Fenestration as an Overlooked Cause of Stroke in a 4 Year Old. 隐藏的罪魁祸首:大脑中动脉开窗是4岁儿童中风的一个被忽视的原因。
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-01 Epub Date: 2025-03-25 DOI: 10.4103/aian.aian_1088_24
Pallav Bhatter, Vipul Gupta, Pallav Kumar, Dusa Srinivas Rao, Ujjwal Agarwal, Rajsrinivas Parthasarathy
{"title":"Hidden Culprit: Middle Cerebral Artery Fenestration as an Overlooked Cause of Stroke in a 4 Year Old.","authors":"Pallav Bhatter, Vipul Gupta, Pallav Kumar, Dusa Srinivas Rao, Ujjwal Agarwal, Rajsrinivas Parthasarathy","doi":"10.4103/aian.aian_1088_24","DOIUrl":"10.4103/aian.aian_1088_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"471-473"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Variant in C19orf12 Gene Causing Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) - Case Report and a Brief Review of Indian Literature on MPAN. C19orf12基因引起线粒体膜蛋白相关神经变性(MPAN)的新变异-病例报告和印度关于MPAN的文献综述
IF 1.9 4区 医学
Annals of Indian Academy of Neurology Pub Date : 2025-05-01 Epub Date: 2025-04-12 DOI: 10.4103/aian.aian_939_24
Jayaram Saibaba, Sandeep Sibi, Deepak Amalnath, Dharanipragada Krishna Suri Subrahmanyam
{"title":"Novel Variant in C19orf12 Gene Causing Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) - Case Report and a Brief Review of Indian Literature on MPAN.","authors":"Jayaram Saibaba, Sandeep Sibi, Deepak Amalnath, Dharanipragada Krishna Suri Subrahmanyam","doi":"10.4103/aian.aian_939_24","DOIUrl":"10.4103/aian.aian_939_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":"450-452"},"PeriodicalIF":1.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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