Annals of Indian Academy of Neurology最新文献

{"title":"Novel Variant in C19orf12 Gene Causing Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) - Case Report and a Brief Review of Indian Literature on MPAN.","authors":"Jayaram Saibaba, Sandeep Sibi, Deepak Amalnath, Dharanipragada Krishna Suri Subrahmanyam","doi":"10.4103/aian.aian_939_24","DOIUrl":"https://doi.org/10.4103/aian.aian_939_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperammonemic Encephalopathy due to Underlying Ornithine Transcarbamylase Deficiency.","authors":"Boby V Maramattom, Priniya Saul","doi":"10.4103/aian.aian_1069_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1069_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Tribute to a Gentle Giant (Fondly Called CHIEF).","authors":"Meenakshisundaram Umaiorubahan","doi":"10.4103/aian.aian_260_25","DOIUrl":"https://doi.org/10.4103/aian.aian_260_25","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Usefulness of 131I-MIBG Myocardial Scintigraphy in a Case of Pure Autonomic Failure - First Report in the Literature.","authors":"Ramkumar Sugumaran, Ragavendar Bhuvaneswaran, Jayaram Saibaba, Sunil K Narayan, Sai Kishore Sundarraj, Nandini Pandit","doi":"10.4103/aian.aian_990_24","DOIUrl":"https://doi.org/10.4103/aian.aian_990_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Subcutaneous and Intravenous Immunoglobulin in Patients with Multifocal Motor Neuropathy: A Systematic Review and Meta-analysis.","authors":"Indar Kumar Sharawat, Pragnya Panda, Lesa Dawman, Ananthanarayanan Kasinathan, Prateek Kumar Panda","doi":"10.4103/aian.aian_815_24","DOIUrl":"https://doi.org/10.4103/aian.aian_815_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>Multifocal motor neuropathy (MMN) is an uncommon chronic autoimmune disorder in adults. Several randomized and non-randomized studies with small sample sizes have shown promising results with subcutaneous immunoglobulin (SCIg) in MMN patients who have a stable disease course with intravenous immunoglobulin (IVIg). This systematic review aimed to compare the efficacy of SCIg and IVIg treatment in MMN patients in terms of changes in muscle power, grip strength, motor function, disability, quality of life, as well as adverse effects.</p><p><strong>Methods: </strong>Random- or fixed-effect model was used, as appropriate, to determine the pooled weighted estimates for outcome variables, depending on the degree of heterogeneity. A total of 11 publications from nine studies (110 patients, mean age 54.3 ± 3.4 years, 57% males, duration of illness 9.7 ± 2.4 years) were included in the review.</p><p><strong>Results: </strong>Changes in the Medical Research Council sum score (MRC-SS), grip strength, dexterity, and disability due to neuropathy following IVIg and SCIg administration were comparable (P = 0.30, I² = 9%; P = 0.51, I² = 0%; P = 0.45, I² = 0%; and P = 0.57, I² = 0%, respectively). Changes in health-related quality of life were numerically better with SCIg, although the difference did not reach statistical significance (P = 0.17, I² = 72%,). Over the long term, there was a trend toward fewer disease fluctuations compared to IVIg (P = 0.43), and the efficacy comparable to IVIg was maintained in terms of muscle strength, disability, and quality of life parameters (P = 0.83, 0.85, and 0.59, respectively). The incidence of moderate to severe systemic adverse effects was significantly lower with SCIg infusion compared to previous years when patients received IVIg (P = 0.03).</p><p><strong>Conclusions: </strong>SCIg can be considered an acceptable alternative to IVIg in patients with MMN, with a better safety profile.</p>","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direction-Reversing Positional Nystagmus in Typical Posterior Semicircular Canalolithiasis with Ipsicanal Transformation via Non-ampullary Arm Canalolithiasis to Posterior Cupulolithiasis.","authors":"Ajay K Vats, Andrea Castellucci, Sudhir Kothari, Shreya Vats, Manjiri Patil","doi":"10.4103/aian.aian_842_24","DOIUrl":"https://doi.org/10.4103/aian.aian_842_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel CHKB Mutation Causing Megaconial Congenital Muscular Dystrophy: A Case Report from India.","authors":"Vykuntaraju K Gowda, Varunvenkat M Srinivasan, Vikas Krishnanada, Rima Sathyakumar, Anita Mahadevan","doi":"10.4103/aian.aian_999_24","DOIUrl":"https://doi.org/10.4103/aian.aian_999_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Human Myxovirus Resistance Protein 1 (MxA) in Shunt Infections.","authors":"Reza Syahputra, Dian Kesumapramudya Nurputra, Agung Triono, Elisabeth Siti Herini","doi":"10.4103/aian.aian_895_24","DOIUrl":"https://doi.org/10.4103/aian.aian_895_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dengue-Associated Myelin Oligodendrocyte Glycoprotein Antibody-Positive Longitudinally Extensive Transverse Myelitis.","authors":"Shubhakaran Khichar, Pradeep Lalwani, Nidhi Yadav","doi":"10.4103/aian.aian_1058_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1058_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hidden Culprit: Middle Cerebral Artery Fenestration as an Overlooked Cause of Stroke in a 4 Year Old.","authors":"Pallav Bhatter, Vipul Gupta, Pallav Kumar, Dusa Srinivas Rao, Ujjwal Agarwal, Rajsrinivas Parthasarathy","doi":"10.4103/aian.aian_1088_24","DOIUrl":"https://doi.org/10.4103/aian.aian_1088_24","url":null,"abstract":"","PeriodicalId":8036,"journal":{"name":"Annals of Indian Academy of Neurology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}