Annals of Biomedical Engineering最新文献

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On-field Head Acceleration Exposure Measurements Using Instrumented Mouthguards: Multi-stage Screening to Optimize Data Quality 使用仪器护齿进行现场头部加速度暴露测量:多阶段筛选,优化数据质量。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-08-03 DOI: 10.1007/s10439-024-03592-z
Adam C. Clansey, Daniel Bondi, Rebecca Kenny, David Luke, Zaryan Masood, Yuan Gao, Marko Elez, Songbai Ji, Alexander Rauscher, Paul van Donkelaar, Lyndia C. Wu
{"title":"On-field Head Acceleration Exposure Measurements Using Instrumented Mouthguards: Multi-stage Screening to Optimize Data Quality","authors":"Adam C. Clansey,&nbsp;Daniel Bondi,&nbsp;Rebecca Kenny,&nbsp;David Luke,&nbsp;Zaryan Masood,&nbsp;Yuan Gao,&nbsp;Marko Elez,&nbsp;Songbai Ji,&nbsp;Alexander Rauscher,&nbsp;Paul van Donkelaar,&nbsp;Lyndia C. Wu","doi":"10.1007/s10439-024-03592-z","DOIUrl":"10.1007/s10439-024-03592-z","url":null,"abstract":"<div><p>Instrumented mouthguards (iMGs) are widely applied to measure head acceleration event (HAE) exposure in sports. Despite laboratory validation, on-field factors including potential sensor skull-decoupling and spurious recordings limit data accuracy. Video analysis can provide complementary information to verify sensor data but lacks quantitative kinematics reference information and suffers from subjectivity. The purpose of this study was to develop a rigorous multi-stage screening procedure, combining iMG and video as independent measurements, aimed at improving the quality of on-field HAE exposure measurements. We deployed iMGs and gathered video recordings in a complete university men’s ice hockey varsity season. We developed a four-stage process that involves independent video and sensor data collection (Stage I), general screening (Stage II), cross verification (Stage III), and coupling verification (Stage IV). Stage I yielded 24,596 iMG acceleration events (AEs) and 17,098 potential video HAEs from all games. Approximately 2.5% of iMG AEs were categorized as cross-verified and coupled iMG HAEs after Stage IV, and less than 1/5 of confirmed or probable video HAEs were cross-verified with iMG data during stage III. From Stage I to IV, we observed lower peak kinematics (median peak linear acceleration from 36.0 to 10.9 g; median peak angular acceleration from 3922 to 942 rad/s<sup>2</sup>) and reduced high-frequency signals, indicative of potential reduction in kinematic noise. Our study proposes a rigorous process for on-field data screening and provides quantitative evidence of data quality improvements using this process. Ensuring data quality is critical in further investigation of potential brain injury risk using HAE exposure data.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 10","pages":"2666 - 2677"},"PeriodicalIF":3.0,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endothelial Cell Transcription Modulation in Cerebral Aneurysms After Endovascular Flow Diversion 血管内血流分流后脑动脉瘤的内皮细胞转录调控
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-08-02 DOI: 10.1007/s10439-024-03591-0
Guilherme Barros, Emma Federico, Patrick Fillingham, Pritha Chanana, Naoki Kaneko, Ying Zheng, Louis J. Kim, Michael R. Levitt
{"title":"Endothelial Cell Transcription Modulation in Cerebral Aneurysms After Endovascular Flow Diversion","authors":"Guilherme Barros,&nbsp;Emma Federico,&nbsp;Patrick Fillingham,&nbsp;Pritha Chanana,&nbsp;Naoki Kaneko,&nbsp;Ying Zheng,&nbsp;Louis J. Kim,&nbsp;Michael R. Levitt","doi":"10.1007/s10439-024-03591-0","DOIUrl":"10.1007/s10439-024-03591-0","url":null,"abstract":"<div><h3>Purpose</h3><p>Flow diverting stents (FDS) are used to treat cerebral aneurysms, by promoting thrombosis and occlusion of the aneurysm sac. However, retreatment is required in some cases, and the biologic basis behind treatment outcome is not known. The goal of this study was to understand how changes in hemodynamic flow after FDS placement affect aneurysmal endothelial cell (EC) activity.</p><h3>Methods</h3><p>Three-dimensional models of patient-specific aneurysms were created to quantify the EC response to FDS placement. Computational fluid dynamic simulations were used to determine the hemodynamic impact of FDS. Two identical models were created for each patient; into one a FDS was inserted. Each model was then populated with human carotid ECs and subjected to patient-specific pulsatile flow for 24 h. ECs were isolated from aneurysm dome from each model and bulk RNA sequencing was performed.</p><h3>Results</h3><p>Paired untreated and treated models were created for four patients. Aneurysm dome EC analysis revealed 366 (2.6%) significant gene changes between the untreated and FDS conditions, out of 13909 total expressed genes. Gene set enrichment analysis of the untreated models demonstrated enriched gene ontology terms related to cell adhesion, growth/tensile activity, cytoskeletal organization, and calcium ion binding. In the FDS models, enriched terms were related to cellular proliferation, ribosomal activity, RNA splicing, and protein folding.</p><h3>Conclusion</h3><p>Treatment of cerebral aneurysms with FDS induces significant EC gene transcription changes related to aneurysm hemodynamics in patient-specific <i>in vitro</i> 3D-printed models subjected to pulsatile flow. Further investigation is needed into the relationship between transcriptional change and treatment outcome.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 12","pages":"3253 - 3263"},"PeriodicalIF":3.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Academic Citation Partnership: A Predatory Practice that Undermines Scholarly Integrity 学术引用伙伴关系:损害学术诚信的掠夺性做法。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-08-02 DOI: 10.1007/s10439-024-03598-7
Louie Giray
{"title":"Academic Citation Partnership: A Predatory Practice that Undermines Scholarly Integrity","authors":"Louie Giray","doi":"10.1007/s10439-024-03598-7","DOIUrl":"10.1007/s10439-024-03598-7","url":null,"abstract":"<div><p>Recently, academic circles have raised concerns about academic citation partnerships. Many researchers receive emails offering these partnerships, often landing in their spam folders. In this paper, I refer to academic citation partnerships as unethical collaborative arrangements where researchers or authors agree to cite each other's work in their academic publications to enhance their academic profiles, often measured by metrics like the h-index. I discuss the characteristics of such partnerships, individuals, and groups who are commonly involved in academic citation partnerships, and clarify what is not considered an academic citation partnership. I argue that these partnerships are predatory and pose a serious threat to scholarly integrity. Such solicitations blur ethical boundaries by treating citations as commodities, similar to predatory journals and conferences. These partnerships compromise the authenticity of scholarly discourse, artificially inflate perceived impacts, and distort academic evaluations. They undermine the pursuit of knowledge for its intrinsic value and exacerbate inequalities in academia by favoring those who can manipulate citation metrics through resources or networks. Addressing this issue requires a commitment to vigilance and adherence to ethical citation standards, ensuring academic discourse that is intellectually honest and genuinely beneficial to academia.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 11","pages":"2911 - 2915"},"PeriodicalIF":3.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue Engineered 3D Constructs for Volumetric Muscle Loss 组织工程三维结构治疗肌肉体积损失。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-31 DOI: 10.1007/s10439-024-03541-w
Sonal Gahlawat, Doga Oruc, Nikhil Paul, Mark Ragheb, Swati Patel, Oyinkansola Fasasi, Peeyush Sharma, David I. Shreiber, Joseph W. Freeman
{"title":"Tissue Engineered 3D Constructs for Volumetric Muscle Loss","authors":"Sonal Gahlawat,&nbsp;Doga Oruc,&nbsp;Nikhil Paul,&nbsp;Mark Ragheb,&nbsp;Swati Patel,&nbsp;Oyinkansola Fasasi,&nbsp;Peeyush Sharma,&nbsp;David I. Shreiber,&nbsp;Joseph W. Freeman","doi":"10.1007/s10439-024-03541-w","DOIUrl":"10.1007/s10439-024-03541-w","url":null,"abstract":"<div><p>Severe injuries to skeletal muscles, including cases of volumetric muscle loss (VML), are linked to substantial tissue damage, resulting in functional impairment and lasting disability. While skeletal muscle can regenerate following minor damage, extensive tissue loss in VML disrupts the natural regenerative capacity of the affected muscle tissue. Existing clinical approaches for VML, such as soft-tissue reconstruction and advanced bracing methods, need to be revised to restore tissue function and are associated with limitations in tissue availability and donor-site complications. Advancements in tissue engineering (TE), particularly in scaffold design and the delivery of cells and growth factors, show promising potential for regenerating damaged skeletal muscle tissue and restoring function. This article provides a brief overview of the pathophysiology of VML and critiques the shortcomings of current treatments. The subsequent section focuses on the criteria for designing TE scaffolds, offering insights into various natural and synthetic biomaterials and cell types for effectively regenerating skeletal muscle. We also review multiple TE strategies involving both acellular and cellular scaffolds to encourage the development and maturation of muscle tissue and facilitate integration, vascularization, and innervation. Finally, the article explores technical challenges hindering successful translation into clinical applications.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 9","pages":"2325 - 2347"},"PeriodicalIF":3.0,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On-Field Evaluation of Mouthpiece-and-Helmet-Mounted Sensor Data from Head Kinematics in Football 从足球头部运动学角度对口罩和头盔传感器数据进行现场评估。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-25 DOI: 10.1007/s10439-024-03583-0
Ty D. Holcomb, Madison E. Marks, N. Stewart Pritchard, Logan E. Miller, Steve Rowson, Garrett S. Bullock, Jillian E. Urban, Joel D. Stitzel
{"title":"On-Field Evaluation of Mouthpiece-and-Helmet-Mounted Sensor Data from Head Kinematics in Football","authors":"Ty D. Holcomb,&nbsp;Madison E. Marks,&nbsp;N. Stewart Pritchard,&nbsp;Logan E. Miller,&nbsp;Steve Rowson,&nbsp;Garrett S. Bullock,&nbsp;Jillian E. Urban,&nbsp;Joel D. Stitzel","doi":"10.1007/s10439-024-03583-0","DOIUrl":"10.1007/s10439-024-03583-0","url":null,"abstract":"<div><h3>Purpose</h3><p>Wearable sensors are used to measure head impact exposure in sports. The Head Impact Telemetry (HIT) System is a helmet-mounted system that has been commonly utilized to measure head impacts in American football. Advancements in sensor technology have fueled the development of alternative sensor methods such as instrumented mouthguards. The objective of this study was to compare peak magnitude measured from high school football athletes dually instrumented with the HIT System and a mouthpiece-based sensor system.</p><h3>Methods</h3><p>Data was collected at all contact practices and competitions over a single season of spring football. Recorded events were observed and identified on video and paired using event timestamps. Paired events were further stratified by removing mouthpiece events with peak resultant linear acceleration below 10 g and events with contact to the facemask or body of athletes.</p><h3>Results</h3><p>A total of 133 paired events were analyzed in the results. There was a median difference (mouthpiece subtracted from HIT System) in peak resultant linear and rotational acceleration for concurrently measured events of 7.3 g and 189 rad/s<sup>2</sup>. Greater magnitude events resulted in larger kinematic differences between sensors and a Bland Altman analysis found a mean bias of 8.8 g and 104 rad/s<sup>2</sup>, respectively.</p><h3>Conclusion</h3><p>If the mouthpiece-based sensor is considered close to truth, the results of this study are consistent with previous HIT System validation studies indicating low error on average but high scatter across individual events. Future researchers should be mindful of sensor limitations when comparing results collected using varying sensor technologies.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 10","pages":"2655 - 2665"},"PeriodicalIF":3.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterogeneous Mechanical Stress and Interstitial Fluid Flow Predictions Derived from DCE-MRI for Rat U251N Orthotopic Gliomas 根据 DCE-MRI 对大鼠 U251N 正位胶质瘤的异质机械应力和间质流体流动进行预测
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-24 DOI: 10.1007/s10439-024-03569-y
Julian A. Rey, Katelynn G. Spanick, Glauber Cabral, Isabel N. Rivera-Santiago, Tavarekere N. Nagaraja, Stephen L. Brown, James R. Ewing, Malisa Sarntinoranont
{"title":"Heterogeneous Mechanical Stress and Interstitial Fluid Flow Predictions Derived from DCE-MRI for Rat U251N Orthotopic Gliomas","authors":"Julian A. Rey,&nbsp;Katelynn G. Spanick,&nbsp;Glauber Cabral,&nbsp;Isabel N. Rivera-Santiago,&nbsp;Tavarekere N. Nagaraja,&nbsp;Stephen L. Brown,&nbsp;James R. Ewing,&nbsp;Malisa Sarntinoranont","doi":"10.1007/s10439-024-03569-y","DOIUrl":"10.1007/s10439-024-03569-y","url":null,"abstract":"<div><p>Mechanical stress and fluid flow influence glioma cell phenotype in vitro, but measuring these quantities in vivo continues to be challenging. The purpose of this study was to predict these quantities in vivo, thus providing insight into glioma physiology and potential mechanical biomarkers that may improve glioma detection, diagnosis, and treatment. Image-based finite element models of human U251N orthotopic glioma in athymic rats were developed to predict structural stress and interstitial flow in and around each animal's tumor. In addition to accounting for structural stress caused by tumor growth, our approach has the advantage of capturing fluid pressure-induced structural stress, which was informed by in vivo interstitial fluid pressure (IFP) measurements. Because gliomas and the brain are soft, elevated IFP contributed substantially to tumor structural stress, even inverting this stress from compressive to tensile in the most compliant cases. The combination of tumor growth and elevated IFP resulted in a concentration of structural stress near the tumor boundary where it has the greatest potential to influence cell proliferation and invasion. MRI-derived anatomical geometries and tissue property distributions resulted in heterogeneous interstitial fluid flow with local maxima near cerebrospinal fluid spaces, which may promote tumor invasion and hinder drug delivery. In addition, predicted structural stress and interstitial flow varied markedly between irradiated and radiation-naïve animals. Our modeling suggests that relative to tumors in stiffer tissues, gliomas experience unusual mechanical conditions with potentially important biological (e.g., proliferation and invasion) and clinical consequences (e.g., drug delivery and treatment monitoring).</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 11","pages":"3053 - 3066"},"PeriodicalIF":3.0,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Tear Size and Location on Supraspinatus Tendon Strain During Activities of Daily Living and Physiotherapy 撕裂大小和位置对日常生活活动和物理治疗中冈上肌腱拉伤的影响
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-20 DOI: 10.1007/s10439-024-03538-5
Mason Garcia, Gabriel Landi, Bailee Covan, Daniela Caro, Mohammad Khak, Ahmad Hedayatzadeh Razavi, Joseph P. DeAngelis, Arun J. Ramappa, Ara Nazarian
{"title":"Effect of Tear Size and Location on Supraspinatus Tendon Strain During Activities of Daily Living and Physiotherapy","authors":"Mason Garcia,&nbsp;Gabriel Landi,&nbsp;Bailee Covan,&nbsp;Daniela Caro,&nbsp;Mohammad Khak,&nbsp;Ahmad Hedayatzadeh Razavi,&nbsp;Joseph P. DeAngelis,&nbsp;Arun J. Ramappa,&nbsp;Ara Nazarian","doi":"10.1007/s10439-024-03538-5","DOIUrl":"10.1007/s10439-024-03538-5","url":null,"abstract":"<div><p>The supraspinatus tendon plays a crucial role in shoulder abduction, making it one of the common structures affected by injury. Clinically, crescent-shaped tears are the most commonly seen tear shape. By developing six specimen-specific, three-dimensional, supraspinatus-infraspinatus finite element model with heterogeneous material properties, this study aimed to examine the changes in tissue deformation (maximum principal strain) of the supraspinatus tendon due to specimen-specific material properties and rotator cuff tear size. FE models with small- and medium-sized full-thickness crescent-shaped tears were subjected to loads seen during activities of daily living and physiotherapy. Six fresh-frozen cadaveric shoulders were dissected to mechanically test the supraspinatus tendon and develop and validate FE models that can be used to assess changes in strain due to small (&lt; 1 cm, equivalent to 20-30% of the tendon width) and medium-sized (1–3 cm, equivalent to 40–50% of the tendon width) tears that are located in the middle and posterior regions of the supraspinatus tendon. FE predictions of maximum principal strain at the tear tips were examined to determine whether failure strain was reached during activities of daily living (drinking and brushing teeth) and physiotherapy exercises (prone abduction and external rotation at 90° abduction). No significant differences were observed between the middle and posterior tear failure loads for small- and medium-sized tears. For prone abduction, there was a potential risk for tear progression (exceeded failure strain) for medium-sized tears in the supraspinatus tendon's middle and posterior regions. For external rotation at 90° abduction, one model with a middle tear and two with posterior tears experienced failure. For all daily activity loads, the strain never exceeded the failure strain. Our three-dimensional supraspinatus-infraspinatus FE model shows that small tears appear unlikely to progress based on the regional strain response; however, medium-sized tears are at higher risk during more strenuous physiotherapy exercises. Furthermore, differences in patient-specific tendon material properties are important in determining whether the tear will progress. Therefore, patient-specific management plans based on tear size may be beneficial to improve clinical outcomes.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 9","pages":"2496 - 2508"},"PeriodicalIF":3.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Instrumented Mouthguards During Direct Jaw Impacts Seen in Boxing 拳击比赛中颚骨直接撞击时仪器护齿的准确性。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-19 DOI: 10.1007/s10439-024-03586-x
Jay Venkatraman, Mitchell Z. Abrams, Donald Sherman, Maria Ortiz-Paparoni, Jefferson R. Bercaw, Robert E. MacDonald, Jason Kait, Elizabeth Dimbath, Derek Pang, Alexandra Gray, Jason F. Luck, Cameron R. Bass, Cynthia A. Bir
{"title":"Accuracy of Instrumented Mouthguards During Direct Jaw Impacts Seen in Boxing","authors":"Jay Venkatraman,&nbsp;Mitchell Z. Abrams,&nbsp;Donald Sherman,&nbsp;Maria Ortiz-Paparoni,&nbsp;Jefferson R. Bercaw,&nbsp;Robert E. MacDonald,&nbsp;Jason Kait,&nbsp;Elizabeth Dimbath,&nbsp;Derek Pang,&nbsp;Alexandra Gray,&nbsp;Jason F. Luck,&nbsp;Cameron R. Bass,&nbsp;Cynthia A. Bir","doi":"10.1007/s10439-024-03586-x","DOIUrl":"10.1007/s10439-024-03586-x","url":null,"abstract":"<div><h3>Purpose</h3><p>Measuring head kinematics data is important to understand and develop methods and standards to mitigate head injuries in contact sports. Instrumented mouthguards (iMGs) have been developed to address coupling issues with previous sensors. Although validated with anthropomorphic test devices (ATDs), there is limited post-mortem human subjects (PMHS) data which provides more accurate soft tissue responses. This study evaluated two iMGs (Prevent Biometrics (PRE) and Diversified Technical Systems (DTS) in response to direct jaw impacts.</p><h3>Methods</h3><p>Three unembalmed male cadaver heads were properly fitted with two different boil-and-bite iMGs and impacted with hook (4 m/s) and uppercut (3 m/s) punches. A reference sensor (REF) was rigidly attached to the base of the skull, impact kinematics were transformed to the head center of gravity and linear and angular kinematic data were compared to the iMGs including Peak Linear Acceleration, Peak Angular Acceleration, Peak Angular Velocity, Head Injury Criterion (HIC), HIC duration, and Brain Injury Criterion.</p><h3>Results</h3><p>Compared to the REF sensor, the PRE iMG underpredicted most of the kinematic data with slopes of the validation regression line between 0.72 and 1.04 and the DTS overpredicted all the kinematic data with slopes of the regression line between 1.4 and 8.7.</p><h3>Conclusion</h3><p>While the PRE iMG was closer to the REF sensor compared to the DTS iMG, the results did not support the previous findings reported with use of ATDs. Hence, our study highlights the benefits of using PMHS for validating the accuracy of iMGs since they closely mimic the human body compared to any ATD’s mandible.</p></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 12","pages":"3219 - 3227"},"PeriodicalIF":3.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141722912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Marker-Based Motion Capture of the Human Spine: A Scoping Review of Study Design and Outcomes 基于光学标记的人体脊柱运动捕捉:研究设计与结果范围综述》。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-18 DOI: 10.1007/s10439-024-03567-0
Claudia F. Romero-Flores, Rogelio Bustamante-Bello, Marcos Moya Bencomo, Erick Axel Martinez-Ríos, Luis Montesinos
{"title":"Optical Marker-Based Motion Capture of the Human Spine: A Scoping Review of Study Design and Outcomes","authors":"Claudia F. Romero-Flores,&nbsp;Rogelio Bustamante-Bello,&nbsp;Marcos Moya Bencomo,&nbsp;Erick Axel Martinez-Ríos,&nbsp;Luis Montesinos","doi":"10.1007/s10439-024-03567-0","DOIUrl":"10.1007/s10439-024-03567-0","url":null,"abstract":"<div><p>Biomechanical analysis of the human spine is crucial to understanding injury patterns. Motion capture technology has gained attention due to its non-invasive nature. Nevertheless, traditional motion capture studies consider the spine a single rigid segment, although its alignment changes during movement. Moreover, guidelines that indicate where markers should be placed for a specific exercise do not exist. This study aims to review the methods used to assess spine biomechanics using motion capture systems to determine the marker sets used, the protocols used, the resulting parameters, the analysed activities, and the characteristics of the studied populations. PRISMA guidelines were used to perform a Scoping Review using SCOPUS and Web of Science databases. Fifty-six journal and conference articles from 1997 to 2023 were considered for the analysis. This review showed that Plug-in-Gait is the most used marker set. The lumbar spine is the segment that generates the most interest because of its high mobility and function as a weight supporter. Furthermore, angular position and velocity are the most common outcomes when studying the spine. Walking, standing, and range of movement were the most studied activities compared to sports and work-related activities. Male and female participants were recruited similarly across all included articles. This review presents the motion capture techniques and measurement outcomes of biomechanical studies of the human spine, to help standardize the field. This work also discusses trends in marker sets, study outcomes, studied segments and segmentation approaches.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><img></picture></div></div></figure></div></div>","PeriodicalId":7986,"journal":{"name":"Annals of Biomedical Engineering","volume":"52 9","pages":"2373 - 2387"},"PeriodicalIF":3.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational Hemodynamics-Based Growth Prediction for Small Abdominal Aortic Aneurysms: Laminar Simulations Versus Large Eddy Simulations 基于计算血流动力学的小型腹主动脉瘤生长预测:层流模拟与大涡流模拟。
IF 3 2区 医学
Annals of Biomedical Engineering Pub Date : 2024-07-17 DOI: 10.1007/s10439-024-03572-3
Mostafa Rezaeitaleshmahalleh, Zonghan Lyu, Nan Mu, Min Wang, Xiaoming Zhang, Todd E. Rasmussen, Robert D. McBane II, Jingfeng Jiang
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