APL Materials最新文献

{"title":"Neuralized and vascularized fast bone regeneration using recombinant humanized type 1 collagen and native bone composite inorganic salts","authors":"Peng Hou, Song Chen, Tuerxun Maimaitiaili, Shengjie Wang, Yan Wei, Jianfei Tang","doi":"10.1063/5.0257593","DOIUrl":"https://doi.org/10.1063/5.0257593","url":null,"abstract":"Bone injury is a prevalent condition in clinical therapy that can lead to significant functional impairments and substantially disrupt the quality of life for patients. However, there has been a limited breakthrough in achieving neuralized and vascularized rapid bone regeneration. In this study, we collaborated with recombinant humanized collagen 1 (rhCOL1), native bone composite inorganic salts (NBCISs), methacrylated silk fibroin (SilMA), and bone marrow mesenchymal stem cells (BMSCs) to construct biomimetic organic and bio-mineralized multifunctional organoids for the repair of bone defects, achieving neuralized and vascularized bone regeneration within just six weeks in rabbits. We first determined the optimal concentration of SilMA (10%) by comprehensively evaluating crosslinking, operability, and BMSC proliferation. The rhCOL1 and NBCIS mixture was prepared using a ratio of 3:7, in reference to native bone, and was subsequently added to create biomimetic organic and biomineralized microenvironments for the NCSilMA. Similarly, the proportions of the added mixture were optimized based on their effects on compressive modulus, swelling, and degradation. As a result, we successfully constructed a biomimetic organic and biomineralized multifunctional hydrogel scaffold for bone defect repair, characterized by excellent biodegradability, appropriate strength, good biocompatibility, and osteoinductive biological function. Finally, the BMSC-loaded NCSilMA (organoids) achieved neuralized and vascularized rapid bone regeneration, with up-regulated osteogenic genes and enhanced cell colonization, collagen, and polysaccharide deposition.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"13 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.aip.org/aip/apm/article-pdf/doi/10.1063/5.0257593/20418432/031103_1_5.0257593.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147334096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low resistivity achieved through enhanced sintering activity in silver paste with submicron particles created through nanoparticle self-assembly","authors":"Chenhe Zhang, Zhe Huang, Panzhen Li, Jin Yang, Siwei Tang, Yunzhu Ma, Wensheng Liu","doi":"10.1063/5.0252843","DOIUrl":"https://doi.org/10.1063/5.0252843","url":null,"abstract":"Silver powder’s size and dispersion affect the performance of conductive silver paste. Micron-sized silver powder has good dispersibility but poor sintering activity at low temperatures. In contrast, silver nano-powder sinters at low temperatures but tends to agglomerate. To address the aforementioned issues, this paper employs a chemical reduction method to prepare high-sintering-activity submicron spherical silver powder with a large number of nanoscale bumps on its surface. The study investigates the effects of various factors on the surface morphology and particle size distribution of the silver powder, including the amount of citric acid added, the speed of the reducing agent’s addition, the pH value, and the temperature of the reaction solutions. In addition, silver pastes with varying silver powder contents (60, 70, 80, and 85 wt. %) were prepared to test their resistivity. The results indicate that the lowest resistivity of 8.9 × 10−6 Ω cm was achieved when the silver powder content was 85 wt. % and the conductive silver paste was sintered at 250 °C for 30 min. Furthermore, the prepared conductive silver pastes maintained good resistivity even when sintered at low temperatures.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"13 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D printing of multifunctional hydrogel scaffolds based on recombinant collagen for bile duct repair","authors":"Jianquan Zhang, Yuanhui Gao, Yijun Yang, Qiuhua Cheng, Longbao Feng, Zhongwen Lei, Xiaoyu Zhang, Yang Xiang","doi":"10.1063/5.0251988","DOIUrl":"https://doi.org/10.1063/5.0251988","url":null,"abstract":"Bile duct injuries remain a significant clinical challenge following hepatobiliary surgeries. Recently, 3D-printed tubular scaffolds have shown promise as effective solutions for bile duct tissue repair. This study presents a novel bi-layered bile duct scaffold, fabricated using advanced three-dimensional printing technology. The inner layer of this scaffold is constructed from poly(ε-caprolactone) methacrylate (PCLMA), which imparts high mechanical strength. The outer layer is composed of biocompatible methacrylated recombinant type I collagen (rColMA) and ε-poly(L-lysine)-methacrylamide (EPLMA), providing excellent antibacterial properties. In addition, encapsulated interleukin-6-loaded liposomes (IL-6@Lip) are incorporated into the outer layer to further promote tissue regeneration. This innovative design creates an optimal microenvironment for the growth and differentiation of bone marrow mesenchymal stem cells (BMSCs) into bile duct-like cells. These differentiated cells contribute to bile duct tissue regeneration, as evidenced by the expression of key differentiation markers, including CK7, CK19, AQP1, AE2, and CX43. The rColMA/EPLMA/IL-6@Lip hydrogel in the outer layer of the scaffold significantly enhances BMSC proliferation and their differentiation into bile duct epithelial cells. Furthermore, in vivo experiments show that the PCLMA//rColMA/EPLMA/IL-6@Lip bi-layered scaffold does not induce bile stasis. This novel, pre-differentiated 3D-printed active scaffold offers valuable insights into bile duct tissue regeneration and replacement research.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"13 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147333146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic micro-protrusion arrays with wrinkled polypyrrole surfaces for enhancing the performance of flexible pressure sensors","authors":"Ruixue Sun, Jie Lu, Pei Li, Pingan Yang, Jianchun Jiang, Mengjie Shou, Changrong Liao","doi":"10.1063/5.0250049","DOIUrl":"https://doi.org/10.1063/5.0250049","url":null,"abstract":"Flexible sensing technology has been developed and improved rapidly in recent years, attracting widespread attention and research. Magnetic composites have great potential in the field of flexible sensing due to their excellent conductivity and magnetic controllability. Here, a performance enhanced flexible double-layer piezocapacitive sensor, PPy-SMPA, was proposed. The sensor consists of a substrate with surface micro-protrusion arrays formed by magnetic materials and a wrinkled PPy sensitive layer polymerized by chemical deposition. The internal micro-capacitance model of the sensor at different pressures was constructed, and the effects of the distribution degree of magnetic particles and the aspect ratio of the micro-protrusion on the equivalent capacitance were discussed. The sensor exhibited excellent cyclic stability, dynamic characteristics, and mechanical durability, with sensitivity reaching five times that of the planar substrate sensor in the low pressure range. On this basis, sensing arrays and grip strength tests were performed to accelerate practical development, and these sensors were integrated into smart insoles for fall detection early warning, demonstrating their potential applications in wearable devices, smart homes, and human health monitoring.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147903601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ionic microsphere therapy for skin trauma","authors":"Jiayin Feng, Fangyan Wang, Xiaoyi Pan, Yunyuan Shao, Anqi Jin, Lanjie Lei, Xiufei Lin","doi":"10.1063/5.0238411","DOIUrl":"https://doi.org/10.1063/5.0238411","url":null,"abstract":"The skin is an important barrier for the body. Normal wound healing can be severely impeded by inadequate angiogenesis, excessive inflammation, and increased susceptibility to infection. Therefore, effective wound therapy should focus on accelerating the healing process and providing antimicrobial properties that are essential for wound recovery. Alginate (ALG) is a biocompatible polysaccharide substance capable of forming hydrogel dressings by cross-linking with metal ions, especially with Zn2+, Fe3+, Cu2+, and Ca2+ metal ions. The hydrogel formed by them can gradually release Zn2+, Fe3+, Cu2+, and Ca2+ during the process of wound repair, which has an important role in promoting angiogenesis and collagen deposition. Here, we prepared hydrogel microspheres (MS) based on cross-linking of different ions such as Zn-MS, Fe-MS, Cu-MS, and Ca-MS and investigated the effect of these ions on wound healing. In vitro and in vivo experiments showed that MS formed by Zn2+ enhanced antimicrobial activity, MS formed by Fe3+ and Cu2+ increased the formation of collagen fibers, and MS formed by Zn2+ and Ca2+ promoted the development of capillaries. So, the hydrogel MS formed by cross-linking ALG with these four ions are of great significance and research value in the field of skin wound application.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"12 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The XLPO cable insulation with synchronous-enhanced DC electrical and high-temperature mechanical properties","authors":"Jinfei Qu, Shihang Wang, Shengtao Li","doi":"10.1063/5.0238546","DOIUrl":"https://doi.org/10.1063/5.0238546","url":null,"abstract":"High voltage direct-current (HVDC) cable is key equipment for utilizing offshore wind power. The high-temperature mechanical and DC electrical properties are two key figures for crosslinked polyethylene cable insulation, which are always contradictory and difficult to satisfy synchronously. To address the problem, we proposed crosslinked polyolefin (XLPO) insulation with 20.3% enhanced high-temperature mechanical stability and improved DC breakdown strength and volume resistivity. The thermally stimulated current results of XLPO showed depolarization current peaks at higher temperatures, responding to better inhibition of space charge and improved DC insulation. In addition, the XLPO exhibited thermodynamic compatibility with only one endothermic peak in differential scanning calorimetry thermograms and decreased small-angle X-ray scattering long-period. The strategy proposed in this work to enhance the comprehensive performance of cable insulation provides a promising route to next-generation HVDC cables.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"12 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147890855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy harvesting and human motion sensing of a 2D piezoelectric hybrid organic–inorganic perovskite","authors":"Li-Jun Ji, Chen Zhao, Tian-Yi Yang, Hai-Run Yang, Muhammad Azeem, Zi-Ying Li, Rui Feng, Guo-Qiang Feng, Sha Li, Wei Li","doi":"10.1063/5.0233435","DOIUrl":"https://doi.org/10.1063/5.0233435","url":null,"abstract":"Two-dimensional (2D) hybrid organic–inorganic perovskites (HOIPs) have garnered plentiful attention as a result of their exceptional structural flexibility and multiple applications. In this study, we present a 2D HOIP (CHA)2PbBr4 (CHA = cyclohexylamine), for its potential applications in piezoelectricity, such as strain energy sensing and harvesting. Flexible composite films of (CHA)2PbBr4/PDMS (PDMS = polydimethylsiloxane) with a sequence of weight ratios (0, 5, 10, 15, 20 wt %) of (CHA)2PbBr4 were fabricated to analyze the energy harvesting properties. Experimental results demonstrated that a device with 15% composition exhibited the most optimized performance in energy harvesting, producing a peak magnitude of output voltage of 11.6 V, a short-circuit current of 0.38 µA, and a power density of 6.77 µW/cm2, along with notable stability exceeding 4000 cycles. Furthermore, this device exhibited high sensitivity in monitoring many varieties of human movements, such as finger bending and tapping, elbow bending, and gentle foot stamping. The findings of this study indicate that this 2D HOIP holds significant potential for use in flexible sensing and intelligent wearable devices.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"18 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of transverse exchange-springs in electrodeposited nano-heterostructured films through first-order reversal curve analysis","authors":"Arindam Samanta, Saibal Roy","doi":"10.1063/5.0223485","DOIUrl":"https://doi.org/10.1063/5.0223485","url":null,"abstract":"The prerequisite of efficient exchange-spring nano-heterostructures, i.e., tuning both hard and soft phases at a nanometer level, has posed significant preparation challenges to ensure effective exchange-coupling. Here, we present a novel approach to fabricate transverse exchange-spring nano-heterostructures using single starting material through an “in situ” electrodeposition technique at room temperature. Utilizing modified acidic bath chemistry and controlled hydrogen evolution, we successfully prepared stress-free, shiny, fine-grained amorphous, and nanocrystalline Co-rich cobalt phosphorus films. These nano-heterostructured films exhibit a unique non-collinear anisotropy-driven transverse exchange-spring behavior, investigated systematically under ambient conditions. The comprehensive functional analyses reveal that intricate interplay between in-plane (IP) anisotropy of amorphous phase and out-of-plane (OOP) anisotropy generating from a nanocrystalline structure compete with each other, while producing characteristic stripe domain structures to novel corrugated stripe domain shapes. The angle-dependent first-order reversal curve distributions demonstrate new insights into the magnetic reversal mechanisms, further confirming the non-exchange-spring and exchange-spring nature of the films depending on the prevalent interfacial exchange coupling. Formation of anisotropy-driven metastable-state due to competition between IP and OOP anisotropy at a particular OOP orientation has led the normal exchange-spring structures to a transverse exchange-spring structure. Micromagnetic simulations, in excellent agreement with experimental data, further elucidate the formation of characteristic stripe domain patterns and the influence of anisotropy on the magnetic properties. The innovative methodology and detailed functional analysis presented here offer significant understanding to the field of exchange-spring magnetic materials, including anisotropy-driven metastable states, demonstrating the potential for scalable and cost-effective fabrication of advanced nano-heterostructures with tailored magnetic properties.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"82 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A first-principles study on structural stability and magnetoelectric coupling of two-dimensional BaTiO3 ultrathin film with Cr and Cu substituting Ti site","authors":"Haigen Gao, Bing Wang","doi":"10.1063/5.0223008","DOIUrl":"https://doi.org/10.1063/5.0223008","url":null,"abstract":"A study on Jahn–Teller distortion reveals that the configuration with Ti-substitution is more stable than that in the case of Ba-replacement. However, magnetoelectric coupling is weak as no spontaneous polarization is formed in the doped unit cell. Taking the atomic radius, low price, and electronegativity into account, Cu was selected to replace Ti together with Cr. Formation energy and phonon spectrum show structural stability. The spontaneous polarization was calculated to be 0.110, 0.114, and 0.247 and 8.078, 0.288, and 0.255 μC/cm2, respectively, in the Cr- and Cu-doped unit cell, corresponding to the directions [100], [010], and [001]. With the application of electric fields, the total magnetic moment was generally enhanced, which resulted in a strong magnetoelectric coupling. In addition, the corresponding coefficient is more than 10 V/cmOe, indicating that the modified BaTiO3 may be a good candidate for single-phase multiferroics. Clearly, co-doping with nonferromagnetic and nonmagnetic elements increases the diversity of new multiferroics.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"13 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid phase epitaxy of SrRuO3 encapsulated by SrTiO3 membranes","authors":"Jieyang Zhou, Mingzhen Feng, Hudson Shih, Yayoi Takamura, Seung Sae Hong","doi":"10.1063/5.0219028","DOIUrl":"https://doi.org/10.1063/5.0219028","url":null,"abstract":"Solid phase epitaxy (SPE) has been widely employed for various thin-film materials, making it valuable for industrial applications due to its scalability. In complex oxides, SPE has been limited to a few materials because of the challenges in maintaining stoichiometric control during growth, particularly when volatile phases are present at high temperatures. Here, we investigate the impact of encapsulation layers on the SPE of complex oxides, using SrRuO3 (SRO) as a model system. An amorphous SRO layer was deposited on a SrTiO3 (STO) substrate, followed by the transfer of a single-crystalline STO membrane as an encapsulation layer in order to suppress the evaporation of volatile species (RuO2) during the SPE process. Whereas both encapsulated and unencapsulated SRO layers were successfully crystallized, the unencapsulated films suffered a substantial loss of Ru ions—exceeding 20%—compared to their encapsulated counterparts. This loss of Ru ions led to a loss of metallicity in the unencapsulated SRO layers, whereas the encapsulated layers retained their metallic ferromagnetic properties. This study demonstrates that the encapsulation provided by oxide membranes effectively suppresses stoichiometric loss during SPE, presenting a new strategy in stabilizing a broader class of functional oxides as epitaxial thin films.","PeriodicalId":7985,"journal":{"name":"APL Materials","volume":"38 1","pages":""},"PeriodicalIF":6.1,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}