Annual review of cell and developmental biology最新文献_第5页

Biogenesis and Regulatory Roles of Circular RNAs. 环状RNA的生物发生和调控作用。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-10-06 Epub Date: 2022-05-24 DOI: 10.1146/annurev-cellbio-120420-125117

Li Yang, Jeremy E Wilusz, Ling-Ling Chen

{"title":"Biogenesis and Regulatory Roles of Circular RNAs.","authors":"Li Yang, Jeremy E Wilusz, Ling-Ling Chen","doi":"10.1146/annurev-cellbio-120420-125117","DOIUrl":"10.1146/annurev-cellbio-120420-125117","url":null,"abstract":"Covalently closed, single-stranded circular RNAs can be produced from viral RNA genomes as well as from the processing of cellular housekeeping noncoding RNAs and precursor messenger RNAs. Recent transcriptomic studies have surprisingly uncovered that many protein-coding genes can be subjected to backsplicing, leading to widespread expression of a specific type of circular RNAs (circRNAs) in eukaryotic cells. Here, we discuss experimental strategies used to discover and characterize diverse circRNAs at both the genome and individual gene scales. We further highlight the current understanding of how circRNAs are generated and how the mature transcripts function. Some circRNAs act as noncoding RNAs to impact gene regulation by serving as decoys or competitors for microRNAs and proteins. Others form extensive networks of ribonucleoprotein complexes or encode functional peptides that are translated in response to certain cellular stresses. Overall, circRNAs have emerged as an important class of RNAmolecules in gene expression regulation that impact many physiological processes, including early development, immune responses, neurogenesis, and tumorigenesis.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":"38 ","pages":"263-289"},"PeriodicalIF":11.3,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119891/pdf/nihms-1888828.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9335458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 50

Tissue Homeostasis and Non-Homeostasis: From Cell Life Cycles to Organ States. 组织稳态与非稳态:从细胞生命周期到器官状态。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-10-06 DOI: 10.1146/annurev-cellbio-120420-114855

Lucy Erin O'Brien

引用次数: 2

Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair. 神经生物学、干细胞生物学和免疫学：了解组织稳态和修复的新兴三位一体。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-10-06 DOI: 10.1146/annurev-cellbio-120320-032429

Emily Scott-Solomon, Ya-Chieh Hsu

引用次数: 0

Physiological Functions of Intracellular Protein Degradation. 细胞内蛋白质降解的生理功能。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-19 DOI: 10.1146/annurev-cellbio-120420-091943

E. McShane, M. Selbach

引用次数: 3

Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. 细胞和组织时空模式的机械化学原理。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-13 DOI: 10.1146/annurev-cellbio-120420-095337

Anaïs Bailles, E. Gehrels, T. Lecuit

{"title":"Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues.","authors":"Anaïs Bailles, E. Gehrels, T. Lecuit","doi":"10.1146/annurev-cellbio-120420-095337","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120420-095337","url":null,"abstract":"Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. Mathematical frameworks have been devised to account for the self-organization of biological patterns, most famously the Turing framework. Patterns can be defined in space, for example, to form stripes; in time, such as during oscillations; or both, to form traveling waves. The formation of these patterns can have different origins: purely chemical, purely mechanical, or a combination of the two. Beyond the variety of molecular implementations of such patterns, we emphasize the unitary principles associated with them, across scales in space and time, within a general mechanochemical framework. We illustrate where such mechanisms of pattern formation arise in biological systems from cellular to tissue scales, with an emphasis on morphogenesis. Our goal is to convey a picture of pattern formation that draws attention to the principles rather than solely specific molecular mechanisms. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44374969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Motor Cooperation During Mitosis and Ciliogenesis. 有丝分裂和脊柱侧弯发生过程中的运动配合。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-05 DOI: 10.1146/annurev-cellbio-121420-100107

G. Ou, J. Scholey

{"title":"Motor Cooperation During Mitosis and Ciliogenesis.","authors":"G. Ou, J. Scholey","doi":"10.1146/annurev-cellbio-121420-100107","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-121420-100107","url":null,"abstract":"Cilia and mitotic spindles are microtubule (MT)-based, macromolecular machines that consecutively assemble and disassemble during interphase and M phase of the cell cycle, respectively, and play fundamental roles in how eukaryotic cells swim through a fluid, sense their environment, and divide to reproduce themselves. The formation and function of these structures depend on several types of cytoskeletal motors, notably MT-based kinesins and dyneins, supplemented by actin-based myosins, which may function independently or collaboratively during specific steps in the pathway of mitosis or ciliogenesis. System-specific differences in these pathways occur because, instead of conforming to a simple one motor-one function rule, ciliary and mitotic motors can be deployed differently by different cell types. This reflects the well-known influence of natural selection on basic molecular processes, creating diversity at subcellular scales. Here we review our current understanding of motor function and cooperation during the assembly-disassembly, maintenance, and functions of cilia and mitotic spindles. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":"1 1","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42067515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Plant Anaphase-Promoting Complex/Cyclosome. 植物后期促进复合体/环小体。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-04-08 DOI: 10.1146/annurev-cellbio-120420-092421

Alex Willems, L. De Veylder

{"title":"The Plant Anaphase-Promoting Complex/Cyclosome.","authors":"Alex Willems, L. De Veylder","doi":"10.1146/annurev-cellbio-120420-092421","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120420-092421","url":null,"abstract":"The anaphase-promoting complex/cyclosome (APC/C) represents a large multisubunit E3-ubiquitin ligase complex that controls the unidirectional progression through the cell cycle by the ubiquitination of specific target proteins, marking them for proteasomal destruction. Although the APC/C's role is largely conserved among eukaryotes, its subunit composition and target spectrum appear to be species specific. In this review, we focus on the plant APC/C complex, whose activity correlates with different developmental processes, including polyploidization and gametogenesis. After an introduction into proteolytic control by ubiquitination, we discuss the composition of the plant APC/C and the essential nature of its core subunits for plant development. Subsequently, we describe the APC/C activator subunits and interactors, most being plant specific. Finally, we provide a comprehensive list of confirmed and suspected plant APC/C target proteins. Identification of growth-related targets might offer opportunities to increase crop yield and resilience of plants to climate change by manipulating APC/C activity. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47599223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A Tale of Three Systems: Toward a Neuroimmunoendocrine Model of Obesity. 三个系统的故事：建立肥胖症的神经免疫内分泌模型。

IF 11.4 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 DOI: 10.1146/annurev-cellbio-120319-114106

Conan J O O'Brien, Emma R Haberman, Ana I Domingos

引用次数: 0

Self-Organization of Cellular Units. 细胞单位的自组织。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 DOI: 10.1146/annurev-cellbio-120319-025356

Timothy J Mitchison, Christine M Field

{"title":"Self-Organization of Cellular Units.","authors":"Timothy J Mitchison, Christine M Field","doi":"10.1146/annurev-cellbio-120319-025356","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120319-025356","url":null,"abstract":"The purpose of this review is to explore self-organizing mechanisms that pattern microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent experiments in frog egg extract. We start by reviewing conceptual distinctions between self-organizing and templating mechanisms for subcellular organization. We then discuss self-organizing mechanisms that generate radial MT arrays and cell centers in the absence of centrosomes. These include autocatalytic MT nucleation, transport of minus ends, and nucleation from organelles such as melanosomes and Golgi vesicles that are also dynein cargoes. We then discuss mechanisms that partition the cytoplasm in syncytia, in which multiple nuclei share a common cytoplasm, starting with cytokinesis, when all metazoan cells are transiently syncytial. The cytoplasm of frog eggs is partitioned prior to cytokinesis by two self-organizing modules, protein regulator of cytokinesis 1 (PRC1)-kinesin family member 4A (KIF4A) and chromosome passenger complex (CPC)-KIF20A. Similar modules may partition longer-lasting syncytia, such as early Drosophila embryos. We end by discussing shared mechanisms and principles for the MT-based self-organization of cellular units.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":"37 ","pages":"23-41"},"PeriodicalIF":11.3,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059766/pdf/nihms-1793618.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10245916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Molecular Mechanisms of Sexually Dimorphic Nervous System Patterning in Flies and Worms. 苍蝇和蠕虫性二态神经系统模式化的分子机制

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 DOI: 10.1146/annurev-cellbio-120319-115237

Stephen F Goodwin, Oliver Hobert

引用次数: 0