Annual review of cell and developmental biology最新文献_第10页

Mitochondria as Cellular and Organismal Signaling Hubs. 线粒体作为细胞和生物体信号中枢。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-10-06 Epub Date: 2022-07-08 DOI: 10.1146/annurev-cellbio-120420-015303

Koning Shen, Corinne L Pender, Raz Bar-Ziv, Hanlin Zhang, Kevin Wickham, Elizabeth Willey, Jenni Durieux, Qazi Ahmad, Andrew Dillin

{"title":"Mitochondria as Cellular and Organismal Signaling Hubs.","authors":"Koning Shen, Corinne L Pender, Raz Bar-Ziv, Hanlin Zhang, Kevin Wickham, Elizabeth Willey, Jenni Durieux, Qazi Ahmad, Andrew Dillin","doi":"10.1146/annurev-cellbio-120420-015303","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120420-015303","url":null,"abstract":"Mitochondria are traditionally known as the powerhouse of the cell, but their functions extend far beyond energy production. They are vital in cellular and organismal pathways that direct metabolism, stress responses, immunity, and cellular fate. To accomplish these tasks, mitochondria have established networks of both intra- and extracellular communication. Intracellularly, these communication routes comprise direct contacts between mitochondria and other subcellular components as well as indirect vesicle transport of ions, metabolites, and other intracellular messengers. Extracellularly, mitochondria can induce stress responses or other cellular changes that secrete mitochondrial cytokine (mitokine) factors that can travel between tissues as well as respond to immune challenges from extracellular sources. Here we provide a current perspective on the major routes of communication for mitochondrial signaling, including their mechanisms and physiological impact. We also review the major diseases and age-related disorders associated with defects in these signaling pathways. An understanding of how mitochondrial signaling controls cellular homeostasis will bring greater insight into how dysfunctional mitochondria affect health in disease and aging.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":"179-218"},"PeriodicalIF":11.3,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40583416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Physiological Functions of Intracellular Protein Degradation. 细胞内蛋白质降解的生理功能。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-19 DOI: 10.1146/annurev-cellbio-120420-091943

E. McShane, M. Selbach

引用次数: 3

Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. 细胞和组织时空模式的机械化学原理。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-13 DOI: 10.1146/annurev-cellbio-120420-095337

Anaïs Bailles, E. Gehrels, T. Lecuit

{"title":"Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues.","authors":"Anaïs Bailles, E. Gehrels, T. Lecuit","doi":"10.1146/annurev-cellbio-120420-095337","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120420-095337","url":null,"abstract":"Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. Mathematical frameworks have been devised to account for the self-organization of biological patterns, most famously the Turing framework. Patterns can be defined in space, for example, to form stripes; in time, such as during oscillations; or both, to form traveling waves. The formation of these patterns can have different origins: purely chemical, purely mechanical, or a combination of the two. Beyond the variety of molecular implementations of such patterns, we emphasize the unitary principles associated with them, across scales in space and time, within a general mechanochemical framework. We illustrate where such mechanisms of pattern formation arise in biological systems from cellular to tissue scales, with an emphasis on morphogenesis. Our goal is to convey a picture of pattern formation that draws attention to the principles rather than solely specific molecular mechanisms. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44374969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Motor Cooperation During Mitosis and Ciliogenesis. 有丝分裂和脊柱侧弯发生过程中的运动配合。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-05-05 DOI: 10.1146/annurev-cellbio-121420-100107

G. Ou, J. Scholey

{"title":"Motor Cooperation During Mitosis and Ciliogenesis.","authors":"G. Ou, J. Scholey","doi":"10.1146/annurev-cellbio-121420-100107","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-121420-100107","url":null,"abstract":"Cilia and mitotic spindles are microtubule (MT)-based, macromolecular machines that consecutively assemble and disassemble during interphase and M phase of the cell cycle, respectively, and play fundamental roles in how eukaryotic cells swim through a fluid, sense their environment, and divide to reproduce themselves. The formation and function of these structures depend on several types of cytoskeletal motors, notably MT-based kinesins and dyneins, supplemented by actin-based myosins, which may function independently or collaboratively during specific steps in the pathway of mitosis or ciliogenesis. System-specific differences in these pathways occur because, instead of conforming to a simple one motor-one function rule, ciliary and mitotic motors can be deployed differently by different cell types. This reflects the well-known influence of natural selection on basic molecular processes, creating diversity at subcellular scales. Here we review our current understanding of motor function and cooperation during the assembly-disassembly, maintenance, and functions of cilia and mitotic spindles. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":"1 1","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42067515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Plant Anaphase-Promoting Complex/Cyclosome. 植物后期促进复合体/环小体。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2022-04-08 DOI: 10.1146/annurev-cellbio-120420-092421

Alex Willems, L. De Veylder

{"title":"The Plant Anaphase-Promoting Complex/Cyclosome.","authors":"Alex Willems, L. De Veylder","doi":"10.1146/annurev-cellbio-120420-092421","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120420-092421","url":null,"abstract":"The anaphase-promoting complex/cyclosome (APC/C) represents a large multisubunit E3-ubiquitin ligase complex that controls the unidirectional progression through the cell cycle by the ubiquitination of specific target proteins, marking them for proteasomal destruction. Although the APC/C's role is largely conserved among eukaryotes, its subunit composition and target spectrum appear to be species specific. In this review, we focus on the plant APC/C complex, whose activity correlates with different developmental processes, including polyploidization and gametogenesis. After an introduction into proteolytic control by ubiquitination, we discuss the composition of the plant APC/C and the essential nature of its core subunits for plant development. Subsequently, we describe the APC/C activator subunits and interactors, most being plant specific. Finally, we provide a comprehensive list of confirmed and suspected plant APC/C target proteins. Identification of growth-related targets might offer opportunities to increase crop yield and resilience of plants to climate change by manipulating APC/C activity. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 38 is October 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":""},"PeriodicalIF":11.3,"publicationDate":"2022-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47599223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

A Tale of Three Systems: Toward a Neuroimmunoendocrine Model of Obesity. 三个系统的故事：建立肥胖症的神经免疫内分泌模型。

IF 11.4 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 DOI: 10.1146/annurev-cellbio-120319-114106

Conan J O O'Brien, Emma R Haberman, Ana I Domingos

引用次数: 0

A New Infectious Unit: Extracellular Vesicles Carrying Virus Populations. 一种新的感染单位:携带病毒群的细胞外囊泡。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 Epub Date: 2021-07-16 DOI: 10.1146/annurev-cellbio-040621-032416

Adeline Kerviel, Mengyang Zhang, Nihal Altan-Bonnet

引用次数: 31

Components and Mechanisms of Nuclear Mechanotransduction. 核机械转导的组成和机制。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 Epub Date: 2021-07-02 DOI: 10.1146/annurev-cellbio-120319-030049

Philipp Niethammer

引用次数: 18

Cell Biology of Canonical Wnt Signaling. 典型Wnt信号传导的细胞生物学研究

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 Epub Date: 2021-07-01 DOI: 10.1146/annurev-cellbio-120319-023657

Lauren V Albrecht, Nydia Tejeda-Muñoz, Edward M De Robertis

{"title":"Cell Biology of Canonical Wnt Signaling.","authors":"Lauren V Albrecht, Nydia Tejeda-Muñoz, Edward M De Robertis","doi":"10.1146/annurev-cellbio-120319-023657","DOIUrl":"https://doi.org/10.1146/annurev-cellbio-120319-023657","url":null,"abstract":"Wnt signaling has multiple functions beyond the transcriptional effects of β-catenin stabilization. We review recent investigations that uncover new cell physiological effects through the regulation of Wnt receptor endocytosis, Wnt-induced stabilization of proteins (Wnt-STOP), macropinocytosis, increase in lysosomal activity, and metabolic changes. Many of these growth-promoting effects of canonical Wnt occur within minutes and are independent of new protein synthesis. A key element is the sequestration of glycogen synthase kinase 3 (GSK3) inside multivesicular bodies and lysosomes. Twenty percent of human proteins contain consecutive GSK3 phosphorylation motifs, which in the absence of Wnt can form phosphodegrons for polyubiquitination and proteasomal degradation. Wnt signaling by either the pharmacological inhibition of GSK3 or the loss of tumor-suppressor proteins, such as adenomatous polyposis coli (APC) and Axin1, increases lysosomal acidification, anabolic metabolites, and macropinocytosis, which is normally repressed by the GSK3-Axin1-APC destruction complex. The combination of these cell physiological effects drives cell growth.","PeriodicalId":7944,"journal":{"name":"Annual review of cell and developmental biology","volume":" ","pages":"369-389"},"PeriodicalIF":11.3,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39127329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 51

The Genomics and Cell Biology of Host-Beneficial Intracellular Infections. 宿主有益细胞内感染的基因组学和细胞生物学。

IF 11.3 1区生物学

Annual review of cell and developmental biology Pub Date : 2021-10-06 Epub Date: 2021-07-09 DOI: 10.1146/annurev-cellbio-120219-024122

John P McCutcheon

引用次数: 14