Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance.

IF 11.4 1区 生物学 Q1 CELL BIOLOGY
Kirsty Logan, George Du Toit, Mattia Giovannini, Victor Turcanu, Gideon Lack
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引用次数: 12

Abstract

Pediatric allergic disease is a significant health concern worldwide, and the prevalence of childhood eczema, asthma, allergic rhinitis, and food allergy continues to increase. Evidence to support specific interventions for the prevention of eczema, asthma, and allergic rhinitis is limited, and no consensus on prevention strategies has been reached. Randomized controlled trials investigating the prevention of food allergy via oral tolerance induction and the early introduction of allergenic foods have been successful in reducing peanut and egg allergy prevalence. Infant weaning guidelines in the United Sates were recently amended to actively encourage the introduction of peanut for prevention of peanut allergy.

儿童过敏性疾病,食物过敏和口腔耐受。
儿童过敏性疾病是世界范围内一个重要的健康问题,儿童湿疹、哮喘、过敏性鼻炎和食物过敏的患病率持续增加。支持预防湿疹、哮喘和变应性鼻炎的具体干预措施的证据有限,并且尚未就预防策略达成共识。研究通过口服耐受性诱导和早期引入致敏食物预防食物过敏的随机对照试验已经成功地降低了花生和鸡蛋过敏的患病率。美国最近修订了婴儿断奶指南,积极鼓励引入花生以预防花生过敏。
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来源期刊
CiteScore
19.50
自引率
0.00%
发文量
21
期刊介绍: The Annual Review of Cell and Developmental Biology, established in 1985, comprehensively addresses major advancements in cell and developmental biology. Encompassing the structure, function, and organization of cells, as well as the development and evolution of cells in relation to both single and multicellular organisms, the journal explores models and tools of molecular biology. As of the current volume, the journal has transitioned from gated to open access through Annual Reviews' Subscribe to Open program, making all articles published under a CC BY license.
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