International journal of fertility and menopausal studies最新文献

Effect of oral and transdermal hormone replacement therapy on lipid profile and Lp(a) level in menopausal women with hypercholesterolemia. 口服和透皮激素替代疗法对绝经期高胆固醇血症妇女血脂和Lp(a)水平的影响。

International journal of fertility and menopausal studies Pub Date : 1996-11-01

G Perrone, C Stefanutti, P Galoppi, G Anelli, O Capri, G Lucani, A Vivenzio, B Mazzarella, L Zichella

{"title":"Effect of oral and transdermal hormone replacement therapy on lipid profile and Lp(a) level in menopausal women with hypercholesterolemia.","authors":"G Perrone, C Stefanutti, P Galoppi, G Anelli, O Capri, G Lucani, A Vivenzio, B Mazzarella, L Zichella","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The aim of this randomized clinical study was to evaluate the hormonal replacement therapy (HRT) effect on plasma lipoproteins and Lp(a) profile in 42 menopausal women with primary hypercholesterolemia (total cholesterol > 240 mg/dL).Setting: University clinic.Patients and methods: 42 hypercholesterolemic menopausal women were randomly assigned to the following groups; (1) transdermal estradiol, 50 micrograms + medroxyprogesterone 10 mg/day for days; (2) conjugated equine estrogens, 0.625 mg/day + medroxyprogesterone acetate 10 mg/day for 12 days; (3) no treatment. At baseline and after 3 and 6 months two blood samples were collected with a 24-hour interval in order to reduce intraindividual and laboratory variability. Serum total cholesterol, HDL cholesterol, triglycerides, LDL cholesterol, and Lp(a) were determined.Results: Total cholesterol and LDL cholesterol significantly decreased after 6 months in both treated groups in comparison to untreated women; HDL cholesterol and triglycerides showed only minimal changes. HRT at the dosage utilized in the study did not seem influence the Lp(a) concentrations after 3 and 6 months.Conclusions: Both transdermal and oral estrogens at medium dosage have a favorable influence on total cholesterol and LDL-cholesterol level of hypercholesterolemic menopausal women, but Lp(a) remains resistant to manipulation.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"41 6","pages":"509-15"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19970641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of sperm-agglutinating antibodies on sperm capacitation and acrosome reaction. 精子凝集抗体对精子获能和顶体反应的影响。

International journal of fertility and menopausal studies Pub Date : 1996-11-01

H Bathla, K S Sidhu

引用次数: 0

Selective follicular reduction: what to do with the oocytes? 选择性卵泡减少:卵母细胞怎么办?

International journal of fertility and menopausal studies Pub Date : 1996-11-01

P L Zusterzeel, J A Kremer, I J Duijkers, K M Coenen

{"title":"Selective follicular reduction: what to do with the oocytes?","authors":"P L Zusterzeel, J A Kremer, I J Duijkers, K M Coenen","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the possible benefits of in vitro fertilization (IVF) of oocytes retrieved during selective follicular reduction of supernumerary follicles in non-IVF cycles.Methods: Selective follicular reduction of supernumerary follicles was used to prevent ovarian hyperstimulation syndrome and multiple pregnancies in gonadotropin-stimulated cycles. We analyzed the data of 13 cycles (13 women) retrospectively.Results: Three pregnancies occurred in these 13 cycles (23%), one after intra-uterine insemination and two after timed coitus. In all cycles, oocytes were retrieved, and in 10 cycles fertilization was achieved (77%); in 6 cycles cryo-preservation was successful (46%) and in 3 cycles embryo transfer (ET) was performed (23%). All embryos were of poor quality and no pregnancies occurred after ET of frozen-thawed embryos. The diagnostic value of fertilization failure seems to be low, since one of the patients who failed to show fertilization became spontaneously pregnant afterward.Conclusion: Based on our observations, the beneficial effect of IVF/cryopreservation during selective follicular reduction appears questionable.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"41 6","pages":"506-8"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19972054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of the effects of an estradiol-releasing vaginal ring combined with an oral gestagen versus transdermal estrogen combined with a levonorgestrel-releasing IUD: clinical findings and endometrial response. 雌激素释放阴道环联合口服孕激素与经皮雌激素联合左炔诺孕酮释放宫内节育器效果的比较研究:临床表现和子宫内膜反应。

International journal of fertility and menopausal studies Pub Date : 1996-11-01

D Kalogirou, G Antoniou, P Karakitsos, O Kalogirou, D Antoniou, L Giannikos

{"title":"A comparative study of the effects of an estradiol-releasing vaginal ring combined with an oral gestagen versus transdermal estrogen combined with a levonorgestrel-releasing IUD: clinical findings and endometrial response.","authors":"D Kalogirou, G Antoniou, P Karakitsos, O Kalogirou, D Antoniou, L Giannikos","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Our purpose was to compare the effects of a new estradiol-releasing vaginal ring with an oral progestin versus the efficacy, safety and acceptability of an intrauterine device releasing levonorgestrel combined with estradiol, delivered transdermally from a patch. Climacteric symptoms, bleeding pattern, and endometrial histologic features were studied.Materials and methods: Fifty-six parous, postmenopausal women with urogenital symptoms were allocated to two groups for 1 year\" 28 women receiving estradiol by a vaginal ring (2 mg/3 months) and an oral progestin for 7 days every month and 28 women receiving a continuous transdermal daily dose of 50 micrograms of estradiol with a levonorgestrel-releasing (20 micrograms/day) intrauterine device inserted. All the patients were subjected to vaginosonographic examination followed by thorough pathological examination of uterine curetting samples.Results: A mean endometrial thickness (double layer) of 2.9 and 3.0 mm, respectively, was found to be predictive of normal endometrium. Both treatment regimens effectively relieved urogenital symptoms. Endometrial proliferation was not observed.Conclusions: Treatment of urogenital symptoms in postmenopausal women with these two forms of hormone replacement therapy was shown to be an effective and safe method, exhibiting possible advantages over other methods of treatment.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"41 6","pages":"522-7"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19970643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The successful use of hyperstimulated washed therapeutic donor insemination after standard therapeutic donor insemination has failed. 在标准的治疗性供体授精失败后，成功使用超刺激水洗治疗性供体授精。

International journal of fertility and menopausal studies Pub Date : 1996-11-01

M P Dow, J M Jones, D A Dumesic, Y Lu, S S Shapiro

{"title":"The successful use of hyperstimulated washed therapeutic donor insemination after standard therapeutic donor insemination has failed.","authors":"M P Dow, J M Jones, D A Dumesic, Y Lu, S S Shapiro","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate whether an aggressive therapeutic donor insemination regimen (stimulated folliculogenesis and ovulation plus intrauterine insemination) can produce a better fecundability rate than a more traditional insemination regimen (non-stimulated folliculogenesis plus LH-timed intracervical insemination) in women who have failed to become pregnant during an initial series of six traditional insemination cycles.Design: A retrospective comparison of fecundability rates was undertaken between women undergoing the traditional insemination protocol and those who voluntarily switched to ovarian hyperstimulation coupled with intrauterine insemination.Participants: Eight-two women who failed to become pregnant during an initial series of six intracervical insemination cycles.Results: Fecundability was 5.6% in cycles of continued urinary LH-timed intracervical insemination and 19.4% when the more aggressive regimen was applied. The difference in fecundability between protocols was significant (P < .005).Conclusion: After an initial series of donor inseminations has failed, a more aggressive insemination regimen involving ovarian hyperstimulation followed by washed intrauterine insemination provides a higher fecundability rate than continued intracervical insemination.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"41 6","pages":"516-21"},"PeriodicalIF":0.0,"publicationDate":"1996-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19970645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The mind-body connection--anxiety, panic, mood and compulsion. 身心联系——焦虑，恐慌，情绪和强迫。

International journal of fertility and menopausal studies Pub Date : 1996-11-01

引用次数: 0

Adhesion prevention in laparoscopic surgery. 腹腔镜手术中粘连预防。

International journal of fertility and menopausal studies Pub Date : 1996-09-01

T Tulandi

引用次数: 0

Effects of different amounts of LH on superovulation induction with long-acting GnRH in an IVF program. 不同量的黄体生成素对体外受精中长效GnRH诱导超排卵的影响。

International journal of fertility and menopausal studies Pub Date : 1996-09-01

G Ragni, L De Laurentis, L Perotti, A D Serra, W Vegetti, P G Crosignani

{"title":"Effects of different amounts of LH on superovulation induction with long-acting GnRH in an IVF program.","authors":"G Ragni, L De Laurentis, L Perotti, A D Serra, W Vegetti, P G Crosignani","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate whether different doses of exogenous LH affect IVF outcome.Design: Retrospective analysis of two consecutive trials.Setting: Infertility Unit of 1st Department of Obstetrics and Gynecology, University of Milan, Italy.Patients: Two groups of 40 eumennorrheic patients matched for age and indications for in vitro fertilization.Intervention: After suppression with a GnRH analogue, both groups received equal amounts of FSH in the first five days of stimulation; after this, the proportions of LH administered were doubled in one group because a different preparation was in use.Main outcome measures: The following observations were compared: number of scans (days to hCG), number of oocytes retrieved, fertilization rate, quality and number of embryos transferred, pregnancy and abortion rate.Results: Doubling the amount of LH administered does not affect any outcome measure except the number of days of stimulation needed prior to hCG administration.Conclusions: No significant difference was seen in terms of number of oocytes, embryo number and quality, pregnancy and abortion rate. The only difference was the length of the stimulation phase.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"41 5","pages":"466-9"},"PeriodicalIF":0.0,"publicationDate":"1996-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19897627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manual removal of the placenta--its role in intrauterine adhesion formation. 人工移除胎盘——它在宫内粘连形成中的作用。

International journal of fertility and menopausal studies Pub Date : 1996-09-01

A Golan, A Raziel, M Pansky, I Bukovsky

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New birth control options. 新的节育选择。

International journal of fertility and menopausal studies Pub Date : 1996-09-01

引用次数: 0