International journal of fertility and menopausal studies最新文献_第10页

International journal of fertility and menopausal studies Pub Date : 1995-03-01

J Y Hare, S Weiner

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Ideal physician-patient relationship at risk. Expansion of managed care and imposition of cost control threaten relationship. 理想的医患关系岌岌可危。管理式医疗的扩张和成本控制的强加威胁着关系。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

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Selective reduction: is there a limit? 选择性还原:有限制吗?

International journal of fertility and menopausal studies Pub Date : 1995-03-01

F J Craparo

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Patterns of serum FSH, LH and hCG after i.m. or i.v. administration of hMG during pituitary suppression. 垂体抑制期间静脉注射hMG后血清FSH、LH和hCG的变化。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

I J Duijkers, H M Hollanders, W N Willemsen, R de Leeuw, H M Vemer

{"title":"Patterns of serum FSH, LH and hCG after i.m. or i.v. administration of hMG during pituitary suppression.","authors":"I J Duijkers, H M Hollanders, W N Willemsen, R de Leeuw, H M Vemer","doi":"","DOIUrl":"","url":null,"abstract":"OBJECTIVE -- The study was undertaken to investigate the effects of a commonly used ovarian stimulation regimen on gonadotropin levels. METHODS -- The behavior of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and human chorionic gonadotropin (hCG) was studied after intramuscular (i.m.) and intravenous (i.v.) human menopausal gonadotropin (hMG) administration. Six female volunteers participated in the study. During pituitary suppression with a gonadotropin-releasing hormone (GnRH) agonist (Buserelin), a single dose of hMG (150 IU) was injected i.m. or i.v., in a cross-over design with an interval of 2 weeks. Blood samples were collected frequently after the injection. Serum concentrations of FSH, specific LH and hCG were determined. RESULTS -- After i.m. administration of hMG, a peak FSH concentration of 7.4 +/- 1.3 U/L was reached after 8 (6-24) hours, with a subsequent decrease. At 0.5 hour after i.v. administration, peak FSH values of 30.5 +/- 5.6 U/L were obtained, followed by a decrease to baseline levels within 48 hours. Exogenous LH and hCG were hardly detectable after i.m. administration of hMG. One-half hour after i.v. injection of hMG, a small increase in specific LH levels to 6.7 +/- 2.6 U/L was shown, followed by a decline. hCG concentrations increased after i.v. hMG administration to 7.6 +/- 1.6 U/L.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 2","pages":"86-91"},"PeriodicalIF":0.0,"publicationDate":"1995-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18604688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Intracervical placement of catheter balloon at hysterosalpingography. 子宫输卵管造影术中导管球囊在宫颈内的放置。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

A J Duleba, M Nachtigall, D L Olive

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Reductive surgery and ovarian function in the human--can reductive ovarian surgery in reproductive age negatively influence fertility and age at onset of menopause? 减容手术与人类卵巢功能——育龄期卵巢减容手术是否会对生育能力和绝经年龄产生负面影响?

International journal of fertility and menopausal studies Pub Date : 1995-03-01

F Melica, S Chiodi, P M Cristoforoni, G B Ravera

{"title":"Reductive surgery and ovarian function in the human--can reductive ovarian surgery in reproductive age negatively influence fertility and age at onset of menopause?","authors":"F Melica, S Chiodi, P M Cristoforoni, G B Ravera","doi":"","DOIUrl":"","url":null,"abstract":"A statistical study was carried out on a cohort of 165 women, menopausal for at least 2 years, who had undergone reductive ovarian surgery in fertile age, against nonoperated controls. The purpose of the study was to examine possible interference caused by surgery on fertility performance and age at which the natural menopause starts. It was found that fertility in the operated women was reduced when compared to the controls, although the difference was not of statistical significance. However, the difference between the two groups in mean age at menopause onset was significant (P < .001). The study sample was divided into two sub-groups according to age at operation (<30/>30) and a significant difference between them was found for age at menopause onset, the under-thirty group starting earlier. In particular, the onset of menopause was even earlier in women who had undergone bilateral wedge biopsy for polycystic ovarian syndrome (PCO). The anatomical state of the ovary at operation was also found to be relevant: ovariectomized women with intrinsic ovarian pathology (cysts, tumors or PCO) started the menopause earlier than those without intrinsic diseases (i.e., ectopic pregnancy), suggesting that such intrinsic pathology may cause a primary depletion of the follicles.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 2","pages":"79-85"},"PeriodicalIF":0.0,"publicationDate":"1995-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18604683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Clinical and hormonal response to short-term intermittent versus continuous oral bromocriptine in hyperprolactinemic women. 高泌乳素血症妇女短期间歇与连续口服溴隐亭的临床和激素反应。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

A Parra, G Crespo, I Coria, A Espinosa de los Monteros

{"title":"Clinical and hormonal response to short-term intermittent versus continuous oral bromocriptine in hyperprolactinemic women.","authors":"A Parra, G Crespo, I Coria, A Espinosa de los Monteros","doi":"","DOIUrl":"","url":null,"abstract":"Unlabelled: OBJECTIVE -- To determine if intermittent oral bromocriptine administration could be a useful therapeutic alternative in infertile hyperprolactinemic women. DESIGN -- Open, randomized and prospective study. SETTING -- Outpatient infertility clinic of a third-level medical institution. PATIENTS -- Fourteen low-income women, 23 to 36 years of age with anovulatory infertility (1-13 years in duration) secondary to hyperprolactinemia (>35 ng/mL). Endocrine profile ruled out anovulation of other origin. INTERVENTIONS -- After a control period of 30 days, seven women (group 1) received daily oral bromocriptine (2.5-10.0 mg/day) continuously during two consecutive 30-day periods (T-1 and T-2), and seven women (group 2) received oral bromocriptine only from day 1 to 15 of each 30-day period of treatment. Morning blood samples were drawn similarly during the three periods on days 6 to 8, 13 to 15, and 21 to 23. MAIN OUTCOME MEASURES -- FSH, LH, and prolactin were determined in all samples, estradiol only in samples of days 6 to 8 and 13 to 15, and progesterone exclusively between days 21 and 23.Results: Mean serum prolactin levels during the control period were similarly elevated in groups 1 and 2. A marked decrease occurred during period T-1 (P < .004) and further during period T-2 (P < .05) in both groups, but at no time were significant intergroup differences documented. During the control period all women had a serum progesterone < 3.0 ng/mL (<9.54 nmol/L); during period T-2 it was > or = 3.0 ng/mL in three and five women of groups 1 and 2, respectively. Over the following 10 months of treatment, two and three normal pregnancies and deliveries ensued in groups 1 and 2, respectively. CONCLUSION -- The intermittent use of oral bromocriptine may indeed be a useful therapeutic approach in treating infertile hyperprolactinemic women.","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 2","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"1995-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18604690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Counteracting postsurgical adhesions--the effect of combining oxidized regenerated cellulose and tissue plasminogen activator. 抗术后粘连——氧化再生纤维素与组织纤溶酶原激活剂结合的效果。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

C Bothin

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Effect of gonadotropin-releasing hormone agonists, nafarelin, buserelin, and leuprolide, on experimentally induced endometriosis in the rat. 促性腺激素释放激素激动剂，纳伐瑞林，布赛瑞林和leuprolide对实验性诱导的大鼠子宫内膜异位症的影响。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

T Mizutani, M Sakata, N Terakawa

{"title":"Effect of gonadotropin-releasing hormone agonists, nafarelin, buserelin, and leuprolide, on experimentally induced endometriosis in the rat.","authors":"T Mizutani, M Sakata, N Terakawa","doi":"","DOIUrl":"","url":null,"abstract":"OBJECTIVE -- The purpose of this study was to compare the potency of the gonadotropin-releasing hormone (GnRH) agonists nafarelin, buserelin, and leuprolide in a newly developed model of experimental endometriosis, thus further characterizing the model. METHODS -- Endometriosis was induced in female rats by autotransplantation of endometrium to a site under the renal capsule. The effect of the GnRH agonists on explant volume and fluid accumulation was evaluated. Binding affinities of the compounds for GnRH receptors in pituitary homogenates of female rats was also measured. RESULTS -- The three GnRH agonists induced significant atrophy and regression of endometriosis. The volume of endometriosis in intact control was 26.1 +/- 4.7 cu.-mm (n = 13), 1.7 +/- 0.1 cu.-mm (n = 12) after therapy with nafarelin, 4.8 +/- 1.8 cu.- mm (n = 7) with buserelin, and 3.7 +/- 1.2 cu.-mm (n = 13) with leuprolide. The effects of these compounds were comparable to that of castration (1.9 +/- 0.5 cu.-mm; n = 10). There was no significant difference in the binding affinities of leuprolide and buserelin for pituitary GnRH receptors. CONCLUSION -- The model was found to be responsive to the GnRH agonist agents evaluated and could discriminate between dosage levels. Potency of the compound seems to correlate with binding affinity to pituitary GnRH","PeriodicalId":79342,"journal":{"name":"International journal of fertility and menopausal studies","volume":"40 2","pages":"106-11"},"PeriodicalIF":0.0,"publicationDate":"1995-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18605419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Ethical guidelines for physicians working in managed care. 从事管理式医疗的医生的道德准则。

International journal of fertility and menopausal studies Pub Date : 1995-03-01

引用次数: 0