The European Physical Journal E最新文献_第3页

Droplet-on-demand using a positive pressure pulse. 使用正压脉冲按需滴注。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-07-02 DOI: 10.1140/epje/s10189-025-00493-4

Mathieu Oléron, Grégoire Clement, Samuel Hidalgo-Caballero, Masoodah Gunny, Finn Box, Matthieu Labousse, Joshua D McGraw

{"title":"Droplet-on-demand using a positive pressure pulse.","authors":"Mathieu Oléron, Grégoire Clement, Samuel Hidalgo-Caballero, Masoodah Gunny, Finn Box, Matthieu Labousse, Joshua D McGraw","doi":"10.1140/epje/s10189-025-00493-4","DOIUrl":"10.1140/epje/s10189-025-00493-4","url":null,"abstract":"<p><p>Droplet generation under steady conditions is a common microfluidic method for producing biphasic systems. However, this process works only over a limited range of imposed pressure: beyond a critical value, a stable liquid jet can instead form. Furthermore, for a given geometry, the pressure conditions set both the generation rate of droplets and their volume. Here, we report on-demand droplet production using a positive pressure pulse to the dispersed-phase inlet of a flow-focusing geometry. This strategy enables confined droplet generation within and beyond the pressure range observed under steady conditions, and decouples volume and production rate. In particular, elongated plugs not possible under steady conditions may be formed when the maximal pressure during the pulse reaches the jet regime. The measured volume of droplets-on-demand as well as the onset of droplet generation are both captured with a simple model that considers hydraulic resistances. This work provides a strategy and design rules for processes that require individual droplets or elongated plugs in a simple microfluidic chip design.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 6-7","pages":"35"},"PeriodicalIF":2.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osmotic pressure induces unexpected relaxation of contractile 3D microtissue. 渗透压诱导收缩的三维显微组织意想不到的松弛。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-06-24 DOI: 10.1140/epje/s10189-025-00497-0

Giovanni Cappello, Fanny Wodrascka, Genesis Marquez-Vivas, Amr Eid Radwan, Parvathy Anoop, Pietro Mascheroni, Jonathan Fouchard, Ben Fabry, Davide Ambrosi, Pierre Recho, Simon de Beco, Martial Balland, Thomas Boudou

{"title":"Osmotic pressure induces unexpected relaxation of contractile 3D microtissue.","authors":"Giovanni Cappello, Fanny Wodrascka, Genesis Marquez-Vivas, Amr Eid Radwan, Parvathy Anoop, Pietro Mascheroni, Jonathan Fouchard, Ben Fabry, Davide Ambrosi, Pierre Recho, Simon de Beco, Martial Balland, Thomas Boudou","doi":"10.1140/epje/s10189-025-00497-0","DOIUrl":"10.1140/epje/s10189-025-00497-0","url":null,"abstract":"<p><p>Cell contraction and proliferation, matrix secretion and external mechanical forces induce compression during embryogenesis and tumor growth, which in turn regulate cell proliferation, metabolism or differentiation. How compression affects tissue contractility, a hallmark of tissue function, is however unknown. Here we apply osmotic compression to microtissues of either mouse colon adenocarcinoma CT26 cells, mouse NIH 3T3 fibroblasts, or human primary colon cancer-associated fibroblasts. Microtissues are anchored to flexible pillars that serve as force transducers. We observe that low-amplitude osmotic compression induces a rapid relaxation of tissue contractility, primed by the deformation of the extracellular matrix. Furthermore, we show that this compression-induced relaxation is independent of the cell type, proportional to the initial tissue contractility, and depends on RhoA-mediated myosin activity. Together, our results demonstrate that compressive stress can relax active tissue force, and points to a potential role of this feedback mechanism during morphogenetic events such as onco- or embryogenesis.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 6-7","pages":"34"},"PeriodicalIF":2.2,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Size distribution of decaying foam bubbles. 衰变泡沫气泡的尺寸分布。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-06-21 DOI: 10.1140/epje/s10189-025-00498-z

Ildoo Kim

引用次数: 0

Roughness exponents of the liquid/vapor/solid contact line on surfaces with dilute random Gaussian defects: numerical study. 稀随机高斯缺陷表面液/气/固接触线的粗糙度指数：数值研究。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-06-16 DOI: 10.1140/epje/s10189-025-00486-3

Stanimir Iliev, Nina Pesheva, Pavel Iliev

{"title":"Roughness exponents of the liquid/vapor/solid contact line on surfaces with dilute random Gaussian defects: numerical study.","authors":"Stanimir Iliev, Nina Pesheva, Pavel Iliev","doi":"10.1140/epje/s10189-025-00486-3","DOIUrl":"10.1140/epje/s10189-025-00486-3","url":null,"abstract":"<p><p>We study here the roughness exponents of the averaged contact line width of a liquid in contact with flat, weakly heterogeneous substrates containing dilute, randomly distributed Gaussian-type defects. For this purpose, we employ the full capillary model. The obtained results for the magnitude of the averaged root-mean-square width of the contact line show that there is only one interval in which the width scales with length as a power function. The numerical studies and analysis indicate that this interval should be regarded as a length scale smaller than the jog length. The roughness exponent found is not a universal constant independent of the apparent contact angle formed by the liquid on the solid surface. It closely approaches the theoretically predicted value of 1/2 [M. O. Robbins, and J. F. Joanny, Europhys. Lett. 3, 729 (1987)] only within the contact angle ranges of <math><msup><mn>10</mn> <mo>∘</mo></msup> </math> to <math><msup><mn>30</mn> <mo>∘</mo></msup> </math> and <math><msup><mn>150</mn> <mo>∘</mo></msup> </math> to <math><msup><mn>170</mn> <mo>∘</mo></msup> </math> . Furthermore, it can be considered that there is still a significant range of contact angles, from <math><msup><mn>55</mn> <mo>∘</mo></msup> </math> up to <math><msup><mn>125</mn> <mo>∘</mo></msup> </math> , in which the roughness exponent remains practically constant, however, having a value of 0.8.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 6-7","pages":"32"},"PeriodicalIF":2.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vivo assessment of kinematic relationships for epithelial morphogenesis. 上皮形态发生运动学关系的体内评估。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-06-15 DOI: 10.1140/epje/s10189-025-00495-2

Toshinori Namba, Kaoru Sugimura, Shuji Ishihara

{"title":"In vivo assessment of kinematic relationships for epithelial morphogenesis.","authors":"Toshinori Namba, Kaoru Sugimura, Shuji Ishihara","doi":"10.1140/epje/s10189-025-00495-2","DOIUrl":"10.1140/epje/s10189-025-00495-2","url":null,"abstract":"<p><p>Tissue growth and deformation result from the combined effects of various cellular events, including cell shape change, cell rearrangement, cell division, and cell death. Resolving and integrating these cellular events is essential for understanding the coordination of tissue-scale growth and deformation by individual cellular behaviors that are critical for morphogenesis, wound healing, and other collective cellular phenomena. For epithelial tissues composed of tightly connected cells, the texture tensor method provides a unified framework for quantifying tissue and cell strains by tracking individual cells in live imaging data. The corresponding kinematic relationships have been introduced in a hydrodynamic model that we previously reported. In this study, we quantitatively evaluated the kinematic equations proposed in the hydrodynamic model using experimental data from a growing Drosophila wing. To accomplish this, we introduced modified definitions of the texture tensor and confirmed that one of these modifications more accurately represents approximated cellular shapes without relying on ad hoc scaling factors. By utilizing the modified tensor, we demonstrated the compatibility of the strain rate tensors and the accuracy of both the kinematic and cell number density equations. These results cross-validate the modified texture analysis and the hydrodynamic model. Furthermore, the precision of the kinematic relationships achieved in this study provides a robust foundation for more advanced integration of modeling and experiment.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 6-7","pages":"31"},"PeriodicalIF":2.2,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart navigation of microswimmers in Poiseuille flow via reinforcement learning. 基于强化学习的泊泽维尔流微游泳者智能导航。

IF 2.2 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-06-12 DOI: 10.1140/epje/s10189-025-00496-1

Priyam Chakraborty, Rahul Roy, Shubhadeep Mandal

引用次数: 0

A simulation study of electrical conductivity of porous rocks: effect of clay, porosity, temperature and Peclet number. 多孔岩石电导率的模拟研究：黏土、孔隙度、温度和Peclet数的影响。

IF 1.8 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-05-27 DOI: 10.1140/epje/s10189-025-00494-3

Supti Sadhukhan, Tapati Dutta

{"title":"A simulation study of electrical conductivity of porous rocks: effect of clay, porosity, temperature and Peclet number.","authors":"Supti Sadhukhan, Tapati Dutta","doi":"10.1140/epje/s10189-025-00494-3","DOIUrl":"10.1140/epje/s10189-025-00494-3","url":null,"abstract":"<p><p>This study investigates the impact of clay content and temperature variation on the electrical conductivity of three-dimensional fluid-filled porous rocks. The role of varying pore throat radii has been included in the course of clay fraction variation in the conducting channels of the rock samples. The research identifies a critical ratio of clay conductance to fluid conductance that dictates the regime of electrical conductance behaviour. A nonlinear increase in electrical conductance is observed when the clay-to-fluid conductance ratio exceeds the critical ratio, whereas a linear relationship is maintained below this critical ratio. A modified form of Archie's law relating effective conductivity and porosity has been proposed for the clay coated channels. The intricate relationship between Peclet number, pore throat size, and temperature on the electrical conductivity of fluid-filled straight channels in three dimensions has also been investigated. Results revealed a quadratic increase in conductance with porosity under steady-state conditions across all Peclet number ranges examined. While the conductivity remained constant with porosity for each Peclet number, the rate of increase in conductivity diminished with it. Nonlinear increase in conductivity was observed with temperature in the transient flow regime with a threshold temperature marking the onset of conductivity. Conductivity was augmented with increase in observation time in the transient state for the entire temperature range considered. Close to the attainment of saturation in electrical conductivity, the conductivity changed linearly with temperature until a steady value was reached.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 4-5","pages":"29"},"PeriodicalIF":1.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamical networking using Gaussian fields 使用高斯场的动态网络

IF 1.8 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-05-24 DOI: 10.1140/epje/s10189-025-00489-0

Nadine du Toit, Kristian K. Müller-Nedebock

{"title":"Dynamical networking using Gaussian fields","authors":"Nadine du Toit, Kristian K. Müller-Nedebock","doi":"10.1140/epje/s10189-025-00489-0","DOIUrl":"10.1140/epje/s10189-025-00489-0","url":null,"abstract":"<p>A novel field theoretical approach towards modelling dynamic networking in complex systems is presented. An equilibrium networking formalism which utilises Gaussian fields is adapted to model the dynamics of particles that can bind and unbind from one another. Here, <i>networking</i> refers to the introduction of instantaneous co-localisation constraints and does not necessitate the formation of a well-defined transient or persistent network. By combining this formalism with Martin–Siggia–Rose generating functionals, a weighted generating functional for the networked system is obtained. The networking formalism introduces spatial and temporal constraints into the Langevin dynamics, via statistical weights, thereby accounting for all possible configurations in which particles can be networked to one another. A simple example of Brownian particles which can bind and unbind from one another demonstrates the tool and that this leads to results for physical quantities in a collective description. Applying the networking formalism to model the dynamics of cross-linking polymers in a mixture, we can calculate the average number of networking instances. As expected, the dynamic structure factors for each type of polymer show that the system collapses once networking is introduced, but that the addition of a repulsive time-dependent potential above a minimum strength prevents this. The examples presented in this paper indicate that this novel approach towards modelling dynamic networking could be applied to a range of synthetic and biological systems to obtain theoretical predictions for experimentally verifiable quantities.</p>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 4-5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1140/epje/s10189-025-00489-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144125868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Travelling-wave gel dipolophoresis of hydrophobic conducting colloids 疏水导电胶体的行波凝胶二极电泳

IF 1.8 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-05-24 DOI: 10.1140/epje/s10189-025-00492-5

Touvia Miloh, Eldad J. Avital

{"title":"Travelling-wave gel dipolophoresis of hydrophobic conducting colloids","authors":"Touvia Miloh, Eldad J. Avital","doi":"10.1140/epje/s10189-025-00492-5","DOIUrl":"10.1140/epje/s10189-025-00492-5","url":null,"abstract":"<div><p>A unified ‘weak-field’ formulation is provided for calculating the combined nonlinear effect of dielectrophoresis and the induced-charge electrophoresis (dipolophoresis) of polarized rigid hydrophobic spherical colloids freely suspended in an electrolyte-saturated Brinkman-hydrogel (porous) medium under a general (direct or alternating currents) non-uniform electric forcing. Explicit expressions for the modified total dipolophoretic mobility of a conducting (metallic) spherical colloid are given in terms of the Brinkman (Darcy), Navier slip, and Debye (screening) length scales. Also presented is a rigorous derivation of the Helmholtz–Smoluchowski slip velocity in terms of these three length scales, including the induced electroosmotic flow field around a hydrophobic rigid colloid embedded in a Brinkman medium that is forced by an arbitrary (non-uniform) ambient electric field. The available solutions for a free (non-porous) electrolyte solution under a uniform forcing and no-slip surface are obtained as limiting cases. For the purpose of illustration, we present and analyse some newly explicit solutions for the mobility and the associated induced-charge electroosmotic velocity field of a slipping colloid set in an effective (hydrogel) porous medium, which is exposed to an ambient ‘sinusoidal’ travelling-wave excitation depending on frequency and wave number.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":790,"journal":{"name":"The European Physical Journal E","volume":"48 4-5","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1140/epje/s10189-025-00492-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144131660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-Markovian equilibrium and non-equilibrium barrier-crossing kinetics in asymmetric double-well potentials 非对称双阱势的非马尔可夫平衡和非平衡势垒穿越动力学

IF 1.8 4区物理与天体物理

The European Physical Journal E Pub Date : 2025-05-22 DOI: 10.1140/epje/s10189-025-00488-1

Laura Lavacchi, Benjamin A. Dalton, Roland R. Netz

引用次数: 0