{"title":"Effets sur l'hémostase de l'injection intraveineuse d'endotoxine","authors":"G.A. Marcel *","doi":"10.1016/S0035-2977(73)80038-0","DOIUrl":"10.1016/S0035-2977(73)80038-0","url":null,"abstract":"<div><p>L'endotoxine agit sur l'hémostase à de nombreux niveaux : elle entraîne des perturbations endothéliales, un « releaseet une agrégagtion plaquettaire, une synthèse accrue de fibrinogène et de facteur VIII, enfin un blocage de l'épuration hépatique des P.D.F. (produits de dégradation du fibrinogène) et de certains facteurs activés. De ceci résulte un tableau de C.I.V. (coagulation intravasculaire) dominé par la chute des plaquettes et du facteur V, l'apparition de P.D.F. et de monomères de fibrine, l'allongement du temps de thrombine et de reptilase et la positivité du test à la protamine.</p><p>L'activation des systèmes de la coagulation et du facteur XII en particulier s'associe à une activation du système kallikréine-kinines, qui joue sans doute un rôle majeur dans la génèse du choc.</p><p>L'héparinothérapie n'est guère indiquée que s'il est indispensable de corriger rapidement le déficit en fibrinogène et/ou en plaquettes par un apport de fractions exogènes. Elle est peut-être utile très précocément, avant la constitution d'une insuffisance rénale aiguë. Elle peut être dangereuse en cas de plaie opératoire. La situation peut également être aggravée par les antifibrinolytiques.</p></div><div><p>Endotoxin acts on hemostasis at many levels : under its influence endothelial cells enter the circulation, platelets release and aggregate, synthesis of factor VIII and of fibrinogen is increased, hepatic clearance of F.D.P. (fibrinogen degradation products) and of certain activated factors is decreased. This leads to D.I.C. (disseminated intravascular coagulation) with drop of platelets and of factor V, presence of F.D.P. and fibrin monomer, lenghtening of thrombin and reptilase times, and positive protamin test.</p><p>Activation of the coagulation system and particularily of factor XII induces an activation of the kallikrein-kinin system, which most likely plays an essential part in the genesis of shock.</p><p>Heparin must be used if it is necessary to correct fibrinogen and/or platelet levels by the use of exogenous fractions. It may also be useful at a very early stage, to prevent renal capillary thrombosis. However heparin can be dangerous in surgical patients. Use of antifibrinolytic drugs can also be dangerous during D.I.C.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"16 1","pages":"Pages 107-114"},"PeriodicalIF":0.0,"publicationDate":"1973-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(73)80038-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15890325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Arnaud, E. Borderon, J.C. Borderon, J. Loulergue, Mlle G. Cazaudare
{"title":"Études sur les contrôles de stérilité du plasma","authors":"R. Arnaud, E. Borderon, J.C. Borderon, J. Loulergue, Mlle G. Cazaudare","doi":"10.1016/S0035-2977(73)80067-7","DOIUrl":"https://doi.org/10.1016/S0035-2977(73)80067-7","url":null,"abstract":"<div><p>La culture de 2 416 flacons de sang périmés et non utilisés a montré que le pourcentage de positivité varie avec le mode de prélèvement.</p><p>Les cultures répétées une fois par mois, pendant 6 mois, de 149 flacons, ont mis en évidence la variabilité des résultats d'un examen à l'autre.</p><p>La contamination volontaire de flacons a prouvé que la souillure devait être relativement importante pour être mise en évidence.</p><p>Les auteurs en tirent des conclusions pour les contrôles bactériologiques du plasma.</p></div><div><p>The culture of 2 416 bottles of outdated and unused blood showed that positive results varied according to the method of collection.</p><p>The variability of results of one examination to another was shown on bottles which underwent repeated monthly cultures during a 6 months period.</p><p>Voluntary contamination of bottles proved that contamination must be at a relatively high level in order to be detected.</p><p>The authors draw up conclusions for the bacteriological controls.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"16 3","pages":"Pages 289-298"},"PeriodicalIF":0.0,"publicationDate":"1973-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(73)80067-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92011395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Groupes sanguins ABO et Rh (D) dans la population turque","authors":"C. Büyükyüksel","doi":"10.1016/S0035-2977(73)80049-5","DOIUrl":"10.1016/S0035-2977(73)80049-5","url":null,"abstract":"<div><p>L'étude de 210.000 fiches appartenant aux sujets qui se sont présentés au centre de transfusion d'Istanbul, durant une période de six ans pour faire vérifier leurs groupes sanguins ou pour faire don de leur sang, a montré que la répartition des groupes sanguins ABO et du facteur Rh(D) dans diverses régions de la Turquie n'est pas homogène.</p></div><div><p>The study of 210.000 cards belonging to persons presenting at the Transfusion Center of Istanbul during a period of six years from 1963 to 1968 for the purpose of blood donation or blood group determination, revealed that the distribution of the ABO blood groups and Rh(D) factor in different régions of Turkey is not homogenous.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"16 4","pages":"Pages 403-410"},"PeriodicalIF":0.0,"publicationDate":"1973-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(73)80049-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15318239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Bertrand, M. Robinet-lévy, H. Michel, J.-M. Lemaire
{"title":"Essai de corrélation entre certaines affections hépatiques et un système précipitant non constitutionnel","authors":"L. Bertrand, M. Robinet-lévy, H. Michel, J.-M. Lemaire","doi":"10.1016/S0035-2977(73)80031-8","DOIUrl":"10.1016/S0035-2977(73)80031-8","url":null,"abstract":"<div><p>Les auteurs ont recherché l'antigène Milan chez des malades atteints ou non d'hépatite virale, de diverses hépatopathies et enfin de maladies générales.</p><p>Ils ont travaillé pendant la période juillet-août 1971 avec un sérum contenant l'anticorps de Milan puis avec des sérums provenant de sujets ayant réagi avec l'anticorps originel.</p><p>Ne voulant considérer que la première période, ils concluent à la non spécificité de cet antigène qui n'a pas, pour l'hépatite virale A, la valeur qu'a l'antigène Australie pour l'hépatite B. Ils considèrent que d'après le contexte clinique il est difficile de dire à quoi correspond ce système précipitant non constitutionnel.</p></div><div><p>The authors studied the Milan antigen in patients with or without viral hepatitis, with various hepatopathies and lastly with general illnesses.</p><p>From July to August 1971, they worked with Milan antibody serum, then with sera from patients having reacted with the original antibody. Taking into consideration the first period only, they concluded that :</p><ul><li><span>--</span><span><p>this antigen called Milan is not specific for viral hepatitis A as it is present without it. Thus is doesn't have the same value as Australia antigen (with which it is sometimes associated);</p></span></li><li><span>--</span><span><p>it seems to be a non constitutional precipitating system. It is possible that it's an abnormal lipoprotein which appears during cholestasis. However, no correlation was found with the bilirubin, cholesterol and lipid levels. According to clinical data, it is difficult to tell with what this non constitutional precipitating system corresponds.</p></span></li></ul></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"16 1","pages":"Pages 33-38"},"PeriodicalIF":0.0,"publicationDate":"1973-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(73)80031-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15475118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Perforation of digestive tract after exchange transfusion. Unusual complication of catheterization of the umbilical vessels].","authors":"J Corberand, P Andrieu, S Bierme, B Boneu, J Pris","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"15 4","pages":"299-312"},"PeriodicalIF":0.0,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15759544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Circulating anticoagulants during hemophilia].","authors":"F Josso, A Cosson, C Gazengel, J P Allain","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"15 4","pages":"281-98"},"PeriodicalIF":0.0,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15759543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Transfusion accident due to ABO incompatibility. Heparin treatment].","authors":"J C Pire, G Potron, B Lardennois, C Freal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"15 4","pages":"331-5"},"PeriodicalIF":0.0,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15759545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sensitive detection of hemagglutinins with lectins].","authors":"G Betail, J Guillot, M Coulet","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"15 4","pages":"271-9"},"PeriodicalIF":0.0,"publicationDate":"1972-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15759542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}