Revue francaise de transfusion最新文献

{"title":"HL-A et maladie de Basedow","authors":"J. Seignalet,&nbsp;C. Jaffiol,&nbsp;L. Baldet,&nbsp;M. Robin,&nbsp;H. Lapinski","doi":"10.1016/S0035-2977(74)80043-X","DOIUrl":"10.1016/S0035-2977(74)80043-X","url":null,"abstract":"<div><p>Les groupes HL-A ont été déterminés chez 100 Caucasiens atteints de maladie de Basedow et comparés avec ceux de 270 témoins sains. 25 antigènes HL-A ont été caractérisés par une microméthode de lymphocytotoxicité. L'analyse des résultats révèle une fréquence augmentée de l'antigène HL-A8 (35 % chez les malades contre 16,3 % chez les témoins), qui est hautement significative sur le plan statistique : p. = 0,0002 et p corrigé (multiplié par 25) = 0,005.</p><p>Nous n'avons observé aucune corrélation évidente entre la présence de l'antigène HL-A8 et différents caractères de la maladie : sexe, âge de début, antécédents familiaux, exophtalmie, goitre, sévérité.</p><p>La connaissance des liaisons unissant le gène HL-A8 à plusieurs affections auto-immunes constitue un argument puissant en faveur de la nature auto-immune de la maladie de Basedow. L'association entre HL-A8 et la maladie de Basedow pourrait s'expliquer par la situation à proximité du second locus HL-A d'un ou plusieurs locus Ir-IgG, occupés chez les individus prédisposés par des allèles « favorisants . Chez de tels sujets, un contact antigénique avec un agent causal exogène entraînerait une réponse immunitaire pathologique, avec production d'IgG thyréo-stimulantes.</p></div><div><p>HL-A typing has been determined in 100 Caucasians with Graves' disease and compared with 270 healthy controls. 25 HL-A antigens were characterized by a lymphocytotoxicity micro-technique. Analysis of the results reveals an increased incidence of HL-A8 antigen (35 % in patients against 16,3 % in controls), with a high degree of statistical significance : p = 0,0002 and p corrected (multiplication times 25) = 0,005.</p><p>We did not observe a clear correlation between the HL-A8 presence and different characters of disease : sex, age of onset, familial history, exophtalmia, goiter, severity.</p><p>The knowledge of links between the HL-A8 gene and several auto-immune diseases in a strong argument in favor of the auto-immune nature of Graves' disease. The association between HL-A8 and Graves' disease would be explained by a close linkage between the second HL-A locus and one or several Ir-IgG locus, occupied in predisposed individuals by « favoringalleles. In these subjects, an antigenic contact with an exogen causal agent would induce a pathologic immune response, with production of thyroïd stimulating IgG.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 4","pages":"Pages 305-321"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80043-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15252023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ictère hémolytique néonatal par anti-D réagissant préférentiellement en milieu enzymatique","authors":"M. Bizot,&nbsp;M. Monis,&nbsp;D. Rieu","doi":"10.1016/S0035-2977(74)80031-3","DOIUrl":"10.1016/S0035-2977(74)80031-3","url":null,"abstract":"<div><p>Les auteurs décrivent un cas d'ictère hémolytique néo-natal chez un enfant Rh + avec réaction directe de Coombs négative et présence d'anti-D libre dans le sérum. Le phénomène a pour cause un anticorps, un allo-anti-D réagissant préférentiellement en milieu enzymatique et les auteurs discutent les conséquences pratiques de l'échec de la réaction à l'antiglobuline et de la technique polybrèneglucose acidifié dans le dépistage de ce type d'anticorps.</p></div><div><p>A case of neonatal haemolytic jaundice in a Rh + child with a negative direct Coombs reaction and with presence of free anti-D in the serum is described. The phenomenon is caused by an antibody, an allo-anti-D which reacts preferentially in enzyme medium. The authors discuss the practical consequence of the failure of the reaction to antiglobulin and the acidified polybrene-glucose method in detecting this type of antibody.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 2","pages":"Pages 151-158"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80031-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15329288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Le Professeur Georges Marchal (1892–1974)","authors":"Georges Bilski-Pasquier,&nbsp;Jean M. Fine","doi":"10.1016/S0035-2977(74)80027-1","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80027-1","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 2","pages":"Pages 119-120"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80027-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90131454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etude de quelques propriétés de la lectine anti (A+B) d'Hygrophorus hypothejus Fr.","authors":"J. Guillot,&nbsp;M. Coulet","doi":"10.1016/S0035-2977(74)80013-1","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80013-1","url":null,"abstract":"<div><p>Les auteurs ont étudié l'activité agglutinante d'extrait d'<em>Hygrophorus hypothejus</em> Fr. anti A + B : avec une agglutination plus marquée des globules B, l'agglutination est inhibée par les oses du groupe II, la N-acétyl-galactosamine et le lactose se montrant de beaucoup les plus actifs. Les particularités de la fixation sur stromas permettent une séparation sous forme purifiée. L'ensemble des propriétés fait conclure à une agglutinine unique, à double effet. Aucun pouvoir mitogène n'a pu être observé.</p></div><div><p>The authors studied the agglutinating activity of <em>Hygrophorus hypothejus</em> Fr. anti A + B extract : with a more pronounced agglutination of the B red blood cells, agglutinin is inhibited by the group II sugars : N-acetyl-D galactosamine and lactose being by far the most active. Because of the characteristics of fixation on stromas, purified forms can be obtained. After studying all the properties, it can be concluded that there is a single agglutinin with a double effect. No mitogenic capacity was observed.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 1","pages":"Pages 49-57"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80013-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92034602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Société Nationale de Transfusion Sanguine","authors":"","doi":"10.1016/S0035-2977(74)80033-7","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80033-7","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 2","pages":"Page 175"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80033-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137229512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informations","authors":"","doi":"10.1016/S0035-2977(74)80034-9","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80034-9","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 2","pages":"Pages 176-177"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80034-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137229513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Société Nationale de Transfusion Sanguine","authors":"","doi":"10.1016/S0035-2977(74)80017-9","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80017-9","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 1","pages":"Pages 93-94"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80017-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136715052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraprotéines monoclonales chez les donneurs de sang du Finistère","authors":"J.P. Saleun,&nbsp;M. Baret","doi":"10.1016/S0035-2977(74)80046-5","DOIUrl":"10.1016/S0035-2977(74)80046-5","url":null,"abstract":"<div><p>Nous avons recherché des paraprotéinémies monoclonales sur un échantillon de 2.000 donneurs de sang pris au hasard au Centre de Transfusion de Brest. Nous avons trouvé une fréquence de cette anomalie de 0.7 %.</p><p>Tous ces sujets ont été suivis pendant au moins une année et sur les 14 cas dépistés, deux se sont avérés être symptomatiques de myélome ou de cryoglobulinémie non diagnostiqués, deux peuvent être suspectés comme étant des myélomes au stade infraclinique, et 10 sont, pour l'instant, considérés comme étant essentiels ou bénins ou asymptomatiques.</p><p>Nous retiendrons le pourcentage élevé de cette anomalie dans notre population et — confirmant des observations précédentes — l'augmentation de cette fréquence vers l'extrême ouest.</p></div><div><p>Occurence of monoclonal paraproteinemia was investigated in a randomized sample of 2.000 blood donnors from Brest blood transfusion center. A yield of 0,7 % was found for this abnormality.</p><p>The 14 cases which were found were followed for at least one year. Two cases were related with non diagnosed myeloma or cryoglobulinemia and two other cases were suspected to be myeloma at on infraclinical stage ; the ten others are yet considered as beeing essential or benign or asymptomatic.</p><p>The high frequency of this abnormality in the French Far-west population is to be noticed and may be related to previously described cases.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 4","pages":"Pages 349-359"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80046-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15328112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L'antigène Du","authors":"Ch. Salmon,&nbsp;A. Gerbal","doi":"10.1016/S0035-2977(74)80019-2","DOIUrl":"10.1016/S0035-2977(74)80019-2","url":null,"abstract":"","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 3","pages":"Pages 195-199"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80019-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15327978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sous-groupes faibles de A et de AB","authors":"M. Garretta,&nbsp;A. Muller,&nbsp;J. Gener,&nbsp;J. Moullec","doi":"10.1016/S0035-2977(74)80012-X","DOIUrl":"https://doi.org/10.1016/S0035-2977(74)80012-X","url":null,"abstract":"<div><p>Sur 150.000 déterminations de groupe ABO effectuées en continu, nous avons détecté 118 phénotypes de sous-groupes faibles de A, dont 14 dans le groupe A et 104 dans le groupe AB. Tous ces groupes ont été refusés par les systèmes Groupamatic * utilisés en routine, et ont été par la suite caractérisés par les techniques manuelles classiques.</p><p>Chez les hétérozygotes, près de 99 % ne semblent pas dus à un allèle au locus ABO, mais plutôt à une interaction entre le gène <em>B</em> et un gène <em>A</em>2 tendant à affaiblir le produit de celui-ci.</p><p>La comparaison de nos pourcentages avec ceux déjà connus nous permet de confirmer une nouvelle fois la remarquable sécurité immunohématologique du système Groupamatic * dans le groupage ABO.</p></div><div><p>On 150.000 ABO groups performed, we have got 118 weak A out of which for A group and 104 for AB group.</p><p>All these were refused by Groupamatic * system in routine, and studied by manual technics.</p><p>For the heterozygotes, about 99 % seem to be not, the product of an allele on the ABO locus, but rather the result of an interaction between <em>B</em> gene and <em>A</em>2 gene.</p><p>Our results compared with known percentages allow us to confirm again the excellent reliability of Groupamatic * system for ABO grouping in routine.</p></div>","PeriodicalId":78648,"journal":{"name":"Revue francaise de transfusion","volume":"17 1","pages":"Pages 41-48"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0035-2977(74)80012-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92091287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}