Anatomy & Cell Biology最新文献_第8页

Anatomical study of variations in the configurations of the circle of Willis in relation to age, sex, and diameters of the components. 对威利斯圈的构造变化与年龄、性别和各部分直径的关系进行解剖学研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-30 DOI: 10.5115/acb.24.020

Yasser Alharbi, Radi Ali M Al Saffar

{"title":"Anatomical study of variations in the configurations of the circle of Willis in relation to age, sex, and diameters of the components.","authors":"Yasser Alharbi, Radi Ali M Al Saffar","doi":"10.5115/acb.24.020","DOIUrl":"10.5115/acb.24.020","url":null,"abstract":"The circle of Willis (COW) refers to the anastomotic arterial network found on the brain base, tasked with provision of collateral circulation aimed at prevention of ischemia. The COW is of immense clinical importance especially with regard to the assessment of neurovascular diseases. Individuals portray significant variations in the COW's anatomical configuration. The present study seeks to evaluate the existing anatomical variations of the COW and within the anterior and posterior segments of the COW. Thus, the study seeks to evaluate the different anatomical variations of the COW and its segments and components within the study population. To attain the set objectives, the present study has utilized the angiographic images for studying the COW variants in patients who underwent cerebral angiography during assessment of different types of cerebral anomalies and conditions. Therefore, this study used conventional angiography as an important tool in the evaluation of the different variations in the COW, and is most appropriate for evaluation of smaller anatomical variations owing to its perfect spatial resolution and portrayal of COW anatomy. The study findings indicated the existence between age and sex, and anatomical variations of the COW, particularly with regard to diameters of COW components like basilar artery (BA), P1, and internal carotid arterys (ICAs). Males had bigger BA, P1 and ICA diameters than females, while individuals aged below 40 years had bigger BA, A1, posterior communicating artery, and ICA diameters than those aged above 40 years.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"579-591"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare variation in popliteal artery branching: anterior tibial artery and fibular artery from the common tibiofibular trunk. 腘动脉分支的罕见变异：来自胫腓总干的胫前动脉和腓动脉。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-07-18 DOI: 10.5115/acb.24.086

Caitlin Sachsenmeier, Debilea Chapel, Randy Kulesza

引用次数: 0

An unreported variant of palmaris longus muscle. 一种未经报道的掌长肌变异。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-19 DOI: 10.5115/acb.24.060

Satheesha Badagabettu Nayak, Vasanthakumar Packiriswamy, Soumya Kodimajalu Vasudeva

引用次数: 0

Platelet-rich plasma protects hippocampal neurons and memory functions in a rat model of vascular dementia. 富血小板血浆可保护血管性痴呆大鼠模型中的海马神经元和记忆功能。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-21 DOI: 10.5115/acb.24.117

Ji-Hyun Moon, Ah La Choi, Hyeon-Jeong Noh, Jae Hwang Song, Geum-Lan Hong, Nam Seob Lee, Young-Gil Jeong, Seung Yun Han

{"title":"Platelet-rich plasma protects hippocampal neurons and memory functions in a rat model of vascular dementia.","authors":"Ji-Hyun Moon, Ah La Choi, Hyeon-Jeong Noh, Jae Hwang Song, Geum-Lan Hong, Nam Seob Lee, Young-Gil Jeong, Seung Yun Han","doi":"10.5115/acb.24.117","DOIUrl":"10.5115/acb.24.117","url":null,"abstract":"Platelet-rich plasma (PRP) is a promising biomaterial rich in bioactive growth factors, offering potential as a therapeutic agent for various diseases. However, its effectiveness in central nervous system disorders like vascular dementia (VaD) remains underexplored. This study investigated the potential of PRP to mitigate VaD progression in vivo. A rat model of VaD was established via bilateral common carotid artery occlusion and hypovolemia operation. Rats were randomly assigned to receive either PRP or platelet-poor plasma (PPP)-the latter being a byproduct of PRP preparation and used as a reference standard-resulting in the groups designated as 'operated group (OP)+PRP' and 'OP+PPP', respectively. PRP or PPP (500 μl) was administered intraperitoneally on the day of the operation and postoperative days 2, 4, 6, and 8. Cognitive function was assessed using the Y-maze, Barnes maze, and passive avoidance tests. On postoperative day 8, hippocampal samples were subjected to histological and semi-quantitative analyses. OP exhibited significant memory decline compared to controls, while the 'OP+PRP' group showed notable improvement. Histological analysis revealed increased neuronal loss and neuroinflammation in OP hippocampi, mitigated in 'OP+PRP'. Semi-quantitative analysis showed decreased expression of brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin receptor kinase B (TrkB) in OP, restored in 'OP+PPP' and further in 'OP+PRP'. These results highlight PRP's protective effects against VaD-induced hippocampal damage and cognitive impairment, partially attributed to BDNF/TrkB pathway upregulation.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"559-569"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical assessment of the Kambin's triangle for percutaneous posterolateral transforaminal endoscopic surgery of lumbar intervertebral discs: a magnetic resonance imaging based study. 腰椎间盘经皮后外侧经椎间孔内窥镜手术的 Kambin 三角区解剖学评估：一项基于磁共振成像的研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-11-08 DOI: 10.5115/acb.24.112

Naeeme Nikpour, Zahra Fazelinejad, Mozhgan Sametzadeh, Mohammad Ardeshiri Lordjani, Ali Reza Eftekhari Moghadam

{"title":"Anatomical assessment of the Kambin's triangle for percutaneous posterolateral transforaminal endoscopic surgery of lumbar intervertebral discs: a magnetic resonance imaging based study.","authors":"Naeeme Nikpour, Zahra Fazelinejad, Mozhgan Sametzadeh, Mohammad Ardeshiri Lordjani, Ali Reza Eftekhari Moghadam","doi":"10.5115/acb.24.112","DOIUrl":"10.5115/acb.24.112","url":null,"abstract":"The aim of the present study was to utilize magnetic resonance imaging (MRI) as a noninvasive tool for evaluation of the Kambin's triangle safe zone. Lumbar MRIs of 67 healthy subjects were analyzed. On the coronal plane, the distance from the superior endplate to the nerve root exiting from the dura (distance a), the distance from the lateral aspect of the dura to the medial aspect of the nerve root (distance b), and the angle between the nerve root and plane of the corresponding disc (angle α) was measured. On the axial plane, the vertical distance from the upper facet surface to the exiting nerve root and root-disc distance was also measured. On the sagittal plane, foraminal height, diameter, nerve root-disc distance, and nerve root-pedicle distance were measured. On the coronal plane, right and left α angle was 50.78±4.43 (range, 48.52-51.84 degrees) and 51.07±4.08 (range, 49.25-51.91) degrees, respectively. Distance of right 'a' was 17.86±3.86 mm (range, 10.56-24.84 mm) and left 'a' was 18.03±3.73 mm (range, 10.98-24.82 mm), distance of right 'b' was 15.57±2.61 mm (range, 10.54-20.70 mm) and left 'b' was 15.46±2.68 mm (range, 10.93-19.23 mm). All these measurements increased as the spine level went down. Foraminal height and diameter decreased caudally. Nerve root-facet distance did not show change as the level went down. The study indicated that radiologic measurement is feasible to evaluate the anatomy of the Kambin's triangle. At lower lumbar levels, the exiting nerve root is at risk of injury.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"523-534"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Localizing motor entry points of adductor muscles of thigh for motor point procedures in the treatment of adductor spasticity. 定位大腿内收肌的运动入口点，用于治疗内收肌痉挛的运动点手术。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-28 DOI: 10.5115/acb.24.065

Anju Mary Albert, Henry Prakash Magimairaj, Jeyaseelan Lakshmanan, Sunil Jonathan Holla, Ivan James Prithishkumar

{"title":"Localizing motor entry points of adductor muscles of thigh for motor point procedures in the treatment of adductor spasticity.","authors":"Anju Mary Albert, Henry Prakash Magimairaj, Jeyaseelan Lakshmanan, Sunil Jonathan Holla, Ivan James Prithishkumar","doi":"10.5115/acb.24.065","DOIUrl":"10.5115/acb.24.065","url":null,"abstract":"Spasticity which is focal or segmental such as affecting a single muscle group or limb can be treated by chemical neurolysis or surgical denervation at the neurovascular hilus. This study determines the motor entry points (MEPs) of adductor muscles of the thigh in the adult Indian population and identifies precise anatomical landmarks for the successful performance motor point procedures for the relief of muscle spasticity. A total of 10 adult lower limbs were dissected, and nerve branches to adductor muscles were carefully exposed up to their MEP. The morphometry of adductor muscles, precise locations of proximal and distal MEPs, and ideal sites for motor point procedures were identified. The median number of MEPs in adductor longus was two. Most of them were located between 40% and 50% of the muscle length i.e., in the third-fifth of the total muscle length. Adductor magnus and gracilis had a median number of one and six MEPs respectively. The ideal site of motor point procedures is in the second-fifth of the muscle length for both. This preliminary study describes the location of MEPs and ideal sites of motor point procedures in the adductor muscle of the thigh. However, further cadaveric and electromyographic studies with larger samples are necessary to investigate precise locations of MEPs aiding in the treatment of spasticity.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"503-510"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142078910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation. 股深动脉在股静脉前方穿过的变异股深动脉：对股静脉插管的解剖学观察。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-10-02 DOI: 10.5115/acb.24.083

Mohammadali M Shoja, Maria-Teresa De Leon, Jay Sheth, Sana Padival, Tara Tritsch, Gary B Schwartz

{"title":"A variant deep femoral artery passing anterior to femoral vein: an anatomical observation with implication in femoral vein cannulation.","authors":"Mohammadali M Shoja, Maria-Teresa De Leon, Jay Sheth, Sana Padival, Tara Tritsch, Gary B Schwartz","doi":"10.5115/acb.24.083","DOIUrl":"10.5115/acb.24.083","url":null,"abstract":"The common femoral artery (CFA) typically gives rise to its superficial and deep branches, with the deep femoral artery (DFA) being the largest and most substantial of these branches. This case study presents a rare variation of the DFA characterized by an unusual branching pattern and its specific relationship with the femoral vein within the subinguinal region. In nutshell, the DFA and the medial femoral circumflex artery shared a common origin from the medial aspect of the CFA. The DFA assumed an unusual course, initially passing anterior to the femoral vein above the saphenofemoral junction, followed by a spiraling trajectory around the medial aspect of the femoral vein before running posteriorly. The embryological origins and clinical implications of this anatomical variation are thoroughly examined. This unusual vascular relationship in the subinguinal region may potentially result in arterial injury during femoral vein cannulation or formation of arteriovenous fistula after the procedure.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"616-620"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual nerve communication in gluteal region: embryological basis and clinical perspective. 臀部异常的神经沟通：胚胎学基础和临床视角。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-10-04 DOI: 10.5115/acb.24.076

Vidhu Dhawan, Sarah Sko Sangma, Suryakanta Seth, Vishwajit Deshmukh, Monica Baxla, Seema Singh

引用次数: 0

Striated muscle fiber crossings of the head and neck: a histological study using near-term human fetuses and elderly cadavers. 头颈部横纹肌纤维交叉：利用近月胎儿和老年尸体进行的组织学研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-07-19 DOI: 10.5115/acb.24.094

Ji Hyun Kim, Kei Kitamura, Yohei Honkura, Gen Murakami, Shin-Ichi Abe

{"title":"Striated muscle fiber crossings of the head and neck: a histological study using near-term human fetuses and elderly cadavers.","authors":"Ji Hyun Kim, Kei Kitamura, Yohei Honkura, Gen Murakami, Shin-Ichi Abe","doi":"10.5115/acb.24.094","DOIUrl":"10.5115/acb.24.094","url":null,"abstract":"Striated muscle fiber crossings at almost right angle are known to exist in the face, soft palate, pharyngeal wall and tongue. We aimed to identify a specific interface tissue at the crossing. We observed histological sections from 22 half-heads of 12 near-term fetuses at 26-40 weeks (crown-rump length, 215-334 mm). For comparison, we also observed tongue frontal sections from 5 elderly cadavers (75-85 years old). At the angle of mouth as well as in the soft palate and pharyngeal wall, a solitary striated muscle fiber (e.g., levator) consistently crossed a fiber bundle of the antagonist muscle (e.g., depressor), but a solitary-to-solitary fiber interdigitation was unlikely with the antagonist muscle. Near the external nasal orifice as well as in the tongue intrinsic muscle layer, at every section, there was a crossing with an endomysium-to-endomysium contact: the nasalis and platysma muscles and; the vertical and transverse (or inferior longitudinal) tongue muscles. Therein, the functional vectors crossed at almost right angle. Also in adult tongue, the vertical and transverse muscle fibers sometimes (0-2 sites per section) crossed with an endomysium-to-endomysium contact. At the muscle crossing with an endomysium contact, the endomysium and basement membrane seemed to receive a friction stress between two muscles. Although some crossings might disappear due to high muscle activity after birth, not a few of them were likely to maintain. To minimize the mechanical stress, a minute nervous control of the timing, duration and strength of muscle contraction seemed to be necessary.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"570-578"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141722829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Edible mushroom (Pleurotus cornucopiae) extract vs. glibenclamide on alloxan induced diabetes: sub-acute in vivo study of Nrf2 expression and renal toxicity. 食用菌提取物与格列本脲对阿脲诱导糖尿病的影响：Nrf2表达和肾毒性的亚急性体内研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-09-30 Epub Date: 2024-07-05 DOI: 10.5115/acb.24.054

Chinedu Godwin Uzomba, Uchenna Kenneth Ezemagu, Mary-Sonia Ofoegbu, Njoku Lydia, Essien Goodness, Chinedum Emelike, Uchewa Obinna, Alo Joseph Nwafor, Ejikeme Felix Mbajiorgu

{"title":"Edible mushroom (Pleurotus cornucopiae) extract vs. glibenclamide on alloxan induced diabetes: sub-acute in vivo study of Nrf2 expression and renal toxicity.","authors":"Chinedu Godwin Uzomba, Uchenna Kenneth Ezemagu, Mary-Sonia Ofoegbu, Njoku Lydia, Essien Goodness, Chinedum Emelike, Uchewa Obinna, Alo Joseph Nwafor, Ejikeme Felix Mbajiorgu","doi":"10.5115/acb.24.054","DOIUrl":"10.5115/acb.24.054","url":null,"abstract":"The study aims to compare the action of Pleurotus cornucopiae and glibenclamide on alloxan-induced diabetes and ascertain how an aqueous extract of the edible mushroom regulates the expression of nuclear factor erythroid 2-related factor 2 (Nrf2), oxidative stress biomarkers and renal toxicity in a diabetic male Wistar rat model. Twenty-five adult male Wistar rats were randomly grouped into five groups with five rats per. Group 1 and those in the treatment groups received normal feed and water ad libitum. Group 2 received intraperitoneal administration of alloxan monohydrate (150 mg/kg body weight). Group 3 received alloxan monohydrate and glibenclamide (5 mg/kg body weight bwt), group 4 received alloxan monohydrate plus the extract (250 mg/kg bwt) and group 5 received alloxan monohydrate plus the extract (500 mg/kg bwt). The administration of glibenclamide plus the extract was oral for 14 days. Glibenclamide and the extract lowered blood glucose level, catalase, and glutathione peroxidase activities, increased the superoxide dismutase (SOD) activity in rats with alloxan induced diabetes. The extract at 500 mg/kg bwt reduced the plasma urea and sodium concentration in the treated rats. The extract and glibenclamide could detoxify alloxan and restore its induced renal degeneration and glomeruli atrophy, intra renal hemorrhage and inflammation and oxidative biomarkers through activation of Nrf2 expression. The drug glibenclamide and P. cornucopiae have appreciable hypoglycemic activity and potential to restore the normal renal architecture in the rats, hence they offer similar curative effects. Additionally, the extract at 500 mg/kg bwt activated SOD and Nrf2 expression more than glibenclamide in rats with alloxan-induced diabetes.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"446-458"},"PeriodicalIF":1.4,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0