Anatomy & Cell Biology最新文献_第8页

A biceps-bicaudatus sartorius muscle: dissection of a variant with possible clinical implications. 肱二头肌-冈底斯肌：解剖变体，可能具有临床意义。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-03 DOI: 10.5115/acb.23.254

Konstantinos Natsis, Christos Koutserimpas, Trifon Totlis, George Triantafyllou, George Tsakotos, Katerina Al Nasraoui, Filippos Karageorgos, Maria Piagkou

引用次数: 0

Impact of peripheral blood mononuclear cells preconditioned by activated platelet supernatant in managing gastric mucosal damage induced by zinc oxide nanoparticles in rats. 用活化血小板上清液预处理外周血单核细胞对控制氧化锌纳米颗粒诱发的大鼠胃黏膜损伤的影响

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-15 DOI: 10.5115/acb.23.217

Darwish Badran, Ayman El-Baz El-Agroudy, Amira Adly Kassab, Khaled Saad El-Bayoumi, Zienab Helmy Eldken, Noha Ramadan Mohammed Elswaidy

{"title":"Impact of peripheral blood mononuclear cells preconditioned by activated platelet supernatant in managing gastric mucosal damage induced by zinc oxide nanoparticles in rats.","authors":"Darwish Badran, Ayman El-Baz El-Agroudy, Amira Adly Kassab, Khaled Saad El-Bayoumi, Zienab Helmy Eldken, Noha Ramadan Mohammed Elswaidy","doi":"10.5115/acb.23.217","DOIUrl":"10.5115/acb.23.217","url":null,"abstract":"The world has witnessed tremendous advancements in nano-base applications. Zinc oxide nanoparticles (ZON) are widely used in food industry and medicine. Although their application is of important value, they may cause toxicity to body tissues. Peripheral blood mononuclear cells (PBMCs) proved its efficacy in tissue regeneration especially when it is preconditioned by activated platelet supernatant (APS). The aim of this study is to evaluate the effect of ZON on the gastric mucosa and the therapeutic role of the PBMCs preconditioned by APS in rats. Ten rats were donors and fifty rats were recipients. The recipients were divided into; control group, ZON group (10 mg/kg/day orally for five days) and preconditioned PBMCs group (1×107 once intravenously 24 hours after ZON). Gastric specimens were processed for histological, immunohistochemical, biochemical and quantitative real-time polymerase chain reaction studies. ZON group showed marked structural changes in the gastric mucosa. There was desquamation or deep ulceration of the epithelium. Cytoplasmic vacuoles and pyknotic nuclei were in glandular cells. Reduced proliferating cell nuclear antigen and increased tumor necrosis factor-α were in epithelial cells. There were significant elevation in malondialdahyde and reduction in glutathione, superoxide dismutase, and catalase. Enhancement in mRNA expression of nuclear factor kappa-B and cyclooxygenase-2 was detected. The preconditioned PBMCs group showed significant improvement of all parameters. So, ZON had cytotoxic effects on the gastric mucosa and the preconditioned PBMCs had a therapeutic effect on gastric mucosal damage after ZON.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"105-118"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139465771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive review of the mental spine. 全面回顾精神脊柱。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-12-15 DOI: 10.5115/acb.23.220

Ross Champagne, Rithvik Vutukuri, Chung Yoh Kim, R Shane Tubbs, Joe Iwanaga

引用次数: 0

Exploring amygdala structural changes and signaling pathways in postmortem brains: consequences of long-term methamphetamine addiction. 探索死后大脑的杏仁核结构变化和信号通路:长期甲基苯丙胺成瘾的后果。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-11-22 DOI: 10.5115/acb.23.193

Zahra Azimzadeh, Samareh Omidvari, Somayeh Niknazar, Saeed Vafaei-Nezhad, Navid Ahmady Roozbahany, Mohammad-Amin Abdollahifar, Foozhan Tahmasebinia, Gholam-Reza Mahmoudiasl, Hojjat Allah Abbaszadeh, Shahram Darabi

{"title":"Exploring amygdala structural changes and signaling pathways in postmortem brains: consequences of long-term methamphetamine addiction.","authors":"Zahra Azimzadeh, Samareh Omidvari, Somayeh Niknazar, Saeed Vafaei-Nezhad, Navid Ahmady Roozbahany, Mohammad-Amin Abdollahifar, Foozhan Tahmasebinia, Gholam-Reza Mahmoudiasl, Hojjat Allah Abbaszadeh, Shahram Darabi","doi":"10.5115/acb.23.193","DOIUrl":"10.5115/acb.23.193","url":null,"abstract":"Methamphetamine (METH) can potentially disrupt neurotransmitters activities in the central nervous system (CNS) and cause neurotoxicity through various pathways. These pathways include increased production of reactive nitrogen and oxygen species, hypothermia, and induction of mitochondrial apoptosis. In this study, we investigated the long-term effects of METH addiction on the structural changes in the amygdala of postmortem human brains and the involvement of the brain- cAMP response element-binding protein/brain-derived neurotrophic factor (CREB/BDNF) and Akt-1/GSK3 signaling pathways. We examined ten male postmortem brains, comparing control subjects with chronic METH users, using immunohistochemistry, real-time polymerase chain reaction (to measure levels of CREB, BDNF, Akt-1, GSK3, and tumor necrosis factor-α [TNF-α]), Tunnel assay, stereology, and assays for reactive oxygen species (ROS), glutathione disulfide (GSSG), and glutathione peroxidase (GPX). The findings revealed that METH significantly reduced the expression of BDNF, CREB, Akt-1, and GPX while increasing the levels of GSSG, ROS, RIPK3, GSK3, and TNF-α. Furthermore, METH-induced inflammation and neurodegeneration in the amygdala, with ROS production mediated by the CREB/BDNF and Akt-1/GSK3 signaling pathways.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"70-84"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138294482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The pterygomandibular raphe: a comprehensive review. 翼下颌剑突：全面回顾。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-30 DOI: 10.5115/acb.23.232

Rithvik Vutukuri, Norio Kitagawa, Keiko Fukino, R Shane Tubbs, Joe Iwanaga

引用次数: 0

A novel histologic description of the fibrous networks in the lid-cheek junction and infraorbital region. 睑颊交界处和眶下区纤维网的新组织学描述。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-26 DOI: 10.5115/acb.23.275

Sang-Hee Lee, Kyu-Ho Yi, Jung-Hee Bae, You-Jin Choi, Young-Chun Gil, Kyung-Seok Hu, Eqram Rahman, Hee-Jin Kim

{"title":"A novel histologic description of the fibrous networks in the lid-cheek junction and infraorbital region.","authors":"Sang-Hee Lee, Kyu-Ho Yi, Jung-Hee Bae, You-Jin Choi, Young-Chun Gil, Kyung-Seok Hu, Eqram Rahman, Hee-Jin Kim","doi":"10.5115/acb.23.275","DOIUrl":"10.5115/acb.23.275","url":null,"abstract":"The aim of this study was to identify the anatomical feature of retaining ligament and fat compartment on the lower eyelid and infraorbital region using a histological method, and to investigate clear definitions for them which could be used generally in the clinical area. Eighteen specimens from eight fresh Korean cadavers were stained with Masson trichrome or hematoxylin and eosin. The ligamentous and fascial fibrous tissue were clearly identified. The ligamentous fibrous tissue which traversed in the superficial and deep fat layer was skin ligament and orbicularis retaining ligament (ORL). The fascial fibrous tissue enclosed the orbicularis oculi muscle (OOc) and circumferencial adipose tissue. Based on the ligamentous and fascial structure, three fat compartments, septal, suborbicularis oculi and infraorbital fat compartment, could be identified. The OOc attached to orbital rim and dermis by ORL and skin ligament, and the muscle fascicle and fat fascicle provided the connection point to the ORL and skin ligament as enclosing all muscle and fat tissue. The combination of the force made by the skin ligament in the lower eyelid and ORL may decide the level and form of the infraorbital grooves.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"25-30"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fenestrated popliteal vein pierced by a branch of the tibial nerve. 被胫神经分支刺穿的腘静脉裂孔。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-08-08 DOI: 10.5115/acb.23.035

Edward C Muo, Joe Iwanaga, Juan J Cardona, Łukasz Olewnik, Aaron S Dumont, R Shane Tubbs

引用次数: 0

Analyzing the factors that contribute to the development of embryological classical type of bladder exstrophy. 分析导致膀胱萎缩胚胎学经典类型发展的因素。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-08-31 DOI: 10.5115/acb.23.056

Ria Margiana, Widya Juwita, Khoirul Ima, Zakiyatul Faizah, Supardi Supardi

{"title":"Analyzing the factors that contribute to the development of embryological classical type of bladder exstrophy.","authors":"Ria Margiana, Widya Juwita, Khoirul Ima, Zakiyatul Faizah, Supardi Supardi","doi":"10.5115/acb.23.056","DOIUrl":"10.5115/acb.23.056","url":null,"abstract":"Bladder exstrophy is a rare congenital condition of the pelvis, bladder, and lower abdomen that opens the bladder against the abdominal wall, produces aberrant growth, short penis, upward curvature during erection, wide penis, and undescended testes. Exstrophy affects 1/30,000 newborns. The bladder opens against the abdominal wall in bladder exstrophy, a rare genitourinary condition. This study is vital to provide appropriate therapy choices as a basis to improve patient outcomes. This study may explain bladder exstrophy and provide treatment. Epispadias, secretory placenta, cloacal exstrophy, and other embryonic abnormalities comprise the exstrophy-spades complex. The mesenchymal layer does not migrate from the ectoderm and endoderm layers in the first trimester, affecting the cloacal membrane. Embryological problems define the exstrophy-aspidistra complex, which resembles epimedium, classic bladder, cloacal exstrophy, and other diseases. Urogenital ventral body wall anomalies expose the bladder mucosa, causing bladder exstrophy. Genetic mutations in the Hedgehog cascade pathway, Wnt signal, FGF, BMP4, Alx4, Gli3, and ISL1 cause ventral body wall closure and urinary bladder failure. External factors such as high maternal age, smoking moms, and high maternal body mass index have also been associated to bladder exstrophy. Valproic acid increases bladder exstrophy risk; chemicals and pollutants during pregnancy may increase bladder exstrophy risk. Bladder exstrophy has no identified cause despite these risk factors. Exstrophy reconstruction seals the bladder, improves bowel function, reconstructs the vaginal region, and restores urination.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"421-427"},"PeriodicalIF":1.1,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10714095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10495139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation. 紫胶叶提取物通过减轻神经炎症来抑制血管性痴呆诱导的记忆障碍和神经元损失。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-09-25 DOI: 10.5115/acb.23.195

Nak Song Sung, Sun Ho Uhm, Hyun Bae Kang, Nam Seob Lee, Young-Gil Jeong, Do Kyung Kim, Nak-Yun Sung, Dong-Sub Kim, Young Choon Yoo, Seung Yun Han

{"title":"Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation.","authors":"Nak Song Sung, Sun Ho Uhm, Hyun Bae Kang, Nam Seob Lee, Young-Gil Jeong, Do Kyung Kim, Nak-Yun Sung, Dong-Sub Kim, Young Choon Yoo, Seung Yun Han","doi":"10.5115/acb.23.195","DOIUrl":"10.5115/acb.23.195","url":null,"abstract":"Vascular dementia (VaD) is characterized by progressive memory impairment, which is associated with microglia-mediated neuroinflammation. Polyphenol-rich natural plants, which possess anti-inflammatory activities, have attracted scientific interest worldwide. This study investigated whether Rubus fruticosus leaf extract (RFLE) can attenuate VaD. Sprague-Dawley rats were separated into five groups: SO, sham-operated and treated with vehicle; OP, operated and treated with vehicle; RFLE-L, operated and treated with low dose (30 mg/kg) of RFLE; RFLE-M, operated and treated with medium dose (60 mg/kg) of RFLE; and RFLE-H, operated and treated with high dose (90 mg/kg) of RFLE. Bilateral common carotid artery and hypotension were used as a modeling procedure, and the RFLE were intraorally administered for 5 days (preoperative 2 and postoperative 3 days). The rats then underwent memory tests including the novel object recognition, Y-maze, Barnes maze, and passive avoidance tests, and neuronal viability and neuroinflammation were quantified in their hippocampi. The results showed that the OP group exhibited VaD-associated memory deficits, neuronal death, and microglial activation in hippocampi, while the RFLE-treated groups showed significant attenuation in all above parameters. Next, using BV-2 microglial cells challenged with lipopolysaccharide (LPS), we evaluated the effects of RFLE in dynamics of proinflammatory mediators and the upstream signaling pathway. RFLE pretreatment significantly inhibited the LPS-induced release of nitric oxide, TNF-α, and IL-6 and upregulation of the MAPKs/NF-κB/iNOS pathway. Collectively, we suggest that RFLE can attenuate the histologic alterations and memory deficits accompanied by VaD, and these roles are, partly due to the attenuation of microglial activation.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"494-507"},"PeriodicalIF":1.1,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10714077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41101387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uncommon configuration of intercostobrachial nerves, lateral roots, and absent medial cutaneous nerve of arm in a cadaveric study. 尸体研究中肋间臂神经、外侧根和缺失的手臂内侧皮神经的罕见配置。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-10-06 DOI: 10.5115/acb.23.149

Rosemol Xaviour

引用次数: 0