Rarinthorn Samrid, Joanna Jaworek-Troć, Tomasz Gładysz, Jerzy A Walocha, Joe Iwanaga, R Shane Tubbs
{"title":"A Y-shaped sphenoidal sinus septum: a case report.","authors":"Rarinthorn Samrid, Joanna Jaworek-Troć, Tomasz Gładysz, Jerzy A Walocha, Joe Iwanaga, R Shane Tubbs","doi":"10.5115/acb.24.284","DOIUrl":"https://doi.org/10.5115/acb.24.284","url":null,"abstract":"<p><p>The sphenoidal sinus septum is one of the most important landmarks during endonasal endoscopic transsphe-noidal operations. During routine coronal sectioning of the face, we found a variant Y-shaped septum in the sphenoidal sinus of a female cadaver. This unusual septum was found between two sections (anterior and posterior sections) and located inferior to the pituitary gland. The sphenoid sinus was divided into three chambers by the septum, <i>i.e.,</i> right, middle, and left. During endoscopic surgery, surgeons should be aware of these variations. To our knowledge, this report documents the first Y-shaped septum of the sphenoidal sinus. Such information can be helpful for surgeons.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David V Rasicci, William C Weirich, Natalie K Yoshioka, Obadah Tolaymat, Najam Siddiqi
{"title":"A constellation of anatomical variation: middle scalene, wrist extensor, and aortic arch variants share embryological origins in cervical somites.","authors":"David V Rasicci, William C Weirich, Natalie K Yoshioka, Obadah Tolaymat, Najam Siddiqi","doi":"10.5115/acb.23.239","DOIUrl":"https://doi.org/10.5115/acb.23.239","url":null,"abstract":"<p><p>During dissection of a 70-year-old male donor, several anatomical variations were observed, highlighted by a bilateral variant middle scalene muscle in the superolateral thoracic wall. The variant scalene muscle was traced from the transverse processes of cervical vertebrae to the fourth rib with a pronounced fascial slip. The elongated middle scalene muscle was thick in girth and abnormally wide at its insertion (56.0 mm), which is hypothesized to reflect compensatory hypertrophy secondary to lung carcinoma. A bilateral wrist extensor variant also was observed as well as an anomalous left vertebral artery from the aortic arch with an abnormal entrance into the vertebral canal. Collectively, these findings represent a constellation of anatomical variations that may be interrelated through altered cervical somite development, providing a fascinating example of how anatomical variations may cluster based on common embryological origin. Clinically, these observations have implications in thoracic outlet syndrome, tendon transfer, and vascular surgery.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hussein Abdellatif, Ruqaiya Al Jabri, Halima Albalushi, Mohamed Al Mushaiqri
{"title":"Liver oval cells in response to HDAC1 inhibitor trichostatin A: immunohistochemical characterization using OV-6 hepatic expression.","authors":"Hussein Abdellatif, Ruqaiya Al Jabri, Halima Albalushi, Mohamed Al Mushaiqri","doi":"10.5115/acb.24.231","DOIUrl":"https://doi.org/10.5115/acb.24.231","url":null,"abstract":"<p><p>Liver regeneration is intricate, involves many cells, and necessitates extended research. This study aimed to investigate the response of liver oval cells (bipotent liver progenitors) to the epigenetic modifier trichostatin A (TSA), an HDAC1 inhibitor, and to develop a scoring system for assessing the response of these cells. Three groups of equally divided rats (n=24) were selected: control (A, dimethyl sulfoxide treated); oval cell induction (B, acetylaminofluorene [2-AAF] to block hepatocyes/carbon tetrachloride [CCL4] to induce oval cell response); and epigenetic modulation (C, TSA post 2-AAF/CCL4 injury). The oval cell response was quantified using immunoreactivity to the OV-6 antibody, and the ductular response was measured by calculating the bile duct (BD) to portal vein (PV) ratio and the percentage of individual oval cells in liver sections. The expression level of HDAC1 was also analyzed. The administration of TSA significantly enhanced oval cell proliferation and the ductular response (6.13±0.28). The control group exhibited limited immunoreactivity to OV-6, while group B showed significant induction of ductular response with distinct morphology (4.13±0.28). The expression levels of HDAC1 were elevated in both the oval cell induction group and the epigenetic modulation group compared to the control group. This study developed a precise method for quantifying liver oval cells and analyzing their response to TSA. TSA administration enhanced oval cell proliferation, suggesting its significance in regulating hepatic progenitor cell dynamics. The findings support the use of epigenetic modifiers in liver regeneration and propose a scoring system for assessing the response of liver oval cells.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xander du Plooy, Yuki Kunisada, Juan J Cardona, Yoko Tabira, Kathleen Carol Bubb, Kazzara Raeburn, Soichiro Ibaragi, Joe Iwanaga, R Shane Tubbs
{"title":"The trochlea for the intermediate tendon of the digastric muscle: a review.","authors":"Xander du Plooy, Yuki Kunisada, Juan J Cardona, Yoko Tabira, Kathleen Carol Bubb, Kazzara Raeburn, Soichiro Ibaragi, Joe Iwanaga, R Shane Tubbs","doi":"10.5115/acb.24.178","DOIUrl":"https://doi.org/10.5115/acb.24.178","url":null,"abstract":"<p><p>This review explores the novel perspective that the intermediate tendon of the digastric muscle may function as an anatomical trochlear pulley system within the human body, challenging the traditional understanding of trochlear systems. While widely recognized trochlear units include structures like the medial part of the humerus and the superior oblique muscle of the orbit, the review focuses on the unique anatomical arrangement of the intermediate tendon of the digastric muscle in connection with the anterior and posterior bellies of the digastric muscles. Despite current debates within the anatomical community about labeling the digastric muscles as having a trochlea, this paper delves into the scientific definition of a trochlear pulley system, presenting the intermediate tendon of the digastric muscle as a potential trochlea.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concurrent variations of left testicular vessels.","authors":"Satheesha Badagabettu Nayak","doi":"10.5115/acb.24.198","DOIUrl":"https://doi.org/10.5115/acb.24.198","url":null,"abstract":"<p><p>Knowledge of variations of the testicular vessels is essential for urologists, radiologists, and surgeons in general, as iatrogenic injuries of these vessels may affect the spermatogenesis severely. Though variations of testicular vessels are common, combined variations of these vessels are rare. We observed concurrent variations of left testicular vessels in an adult cadaver aged 70 years. There were two gonadal arteries on the left side, both of which arose from the abdominal aorta. The superior one among them hooked around the left renal vein and the left suprarenal veins. There were three testicular veins at the deep inguinal ring, but they formed a plexus of veins at the posterior abdominal wall, which reduced into two veins. These two testicular veins terminated into the left renal vein independently. The deep inguinal ring was congested with the presence of five vessels. This variation could increase the possibility of varicocele.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bijo Elsy, Waad Hassan Mohammad Asiri, Lina Eltag Sir Elkhatim Osman, Mansour Abdullah Saeed Alghamdi
{"title":"Origin and branching pattern of the iliohypogastric and ilioinguinal nerves and their exits in relation to the psoas major muscle: a cadaveric study.","authors":"Bijo Elsy, Waad Hassan Mohammad Asiri, Lina Eltag Sir Elkhatim Osman, Mansour Abdullah Saeed Alghamdi","doi":"10.5115/acb.24.175","DOIUrl":"https://doi.org/10.5115/acb.24.175","url":null,"abstract":"<p><p>This study aims to determine the level of origin, branching pattern and exits of the iliohypogastric and ilioinguinal nerves in relation to the psoas major muscle. Additionally, this study confirms the presence and retroperitoneal courses of the double nerves. We dissected a total of 24 iliohypogastric and ilioinguinal nerves (6 male and 6 female cadavers). The origin, branching, and exits in relation to the psoas major muscle, the absence of these nerves or the presence of double nerves, and their retroperitoneal course were carefully examined. All the images were recorded by photographing. In this study, we mainly observed variations in exits, branching patterns, and their retroperitoneal course. The iliohypogastric nerve was absent in 2 cases (8.3%). In the type I pattern, in 1 case (4.2%), the common trunk descends anteriorly to the iliac vessels from the iliolumbar vessels. In 4 cases (16.7%), the double ilioinguinal nerve with different branch patterns and retroperitoneal courses was observed. In 1 single nerve case (4.2%), the ilioinguinal nerve descends anterior to the iliac vessels from the iliolumbar vessels. To our knowledge, the branching pattern of the double ilioinguinal nerves and their retroperitoneal course have not been reported in any available data. Sound knowledge of the variations in the origin, branches, and retroperitoneal course of the iliohypogastric and ilioinguinal nerves is very helpful for the improvement of peripheral nerve blocks and other various surgical procedures to avoid complications and nerve injuries.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anatomical variations and surgical implications of axillary artery branches: an anatomical study of the coracoid process region.","authors":"Pawaree Nonthasaen, Thawanthorn Chaimongkhol, Thanapon Chobpenthai, Pasuk Mahakkanukrauh","doi":"10.5115/acb.24.215","DOIUrl":"https://doi.org/10.5115/acb.24.215","url":null,"abstract":"<p><p>The complex of neurovascular structures surrounding the coracoid process, particularly the axillary artery, the thoracoacromial artery and theirs branches, plays a critical role in shoulder function. Detailed dissection was performed in 36 shoulders from 18 embalmed cadavers. The focus was on axillary artery branches in relation to the coracoid process and the documentation of anatomical variations in this area. Significant findings include the categorization of thoracoacromial artery variations and the identification of acromial and clavicular branches as variable. A key measurement was mean distance between the thoracoacromial artery and tip of the coracoid process (31.89 mm). These findings offer valuable insight into the spatial relationships of these structures. The study provides important information on the vascular anatomy surrounding the coracoid process. Recognizing these anatomical variations is essential for planning safer and more effective shoulder surgeries, such as coracoclavicular stabilization and subcoracoid decompression. Detailed anatomical data are key for surgeons to prevent unintended injuries and enhance surgical success.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun Taek Shim, Ye Hwon Jeong, Nahyun Aum, Hong-Il Ha, Minsung Choi, Jin Young Hyun, Ho-Seung Lee, Yi-Suk Kim
{"title":"A new metric method for sex estimation using three-dimensional imaging of the nuchal crest.","authors":"Yun Taek Shim, Ye Hwon Jeong, Nahyun Aum, Hong-Il Ha, Minsung Choi, Jin Young Hyun, Ho-Seung Lee, Yi-Suk Kim","doi":"10.5115/acb.24.114","DOIUrl":"10.5115/acb.24.114","url":null,"abstract":"<p><p>In Walker's nonmetric method, the nuchal crest serves as the representative region for indicating sexual dimorphism in cranial bones. However, the accuracy of sex estimation using the nuchal crest is lower than that using other anatomical regions. Furthermore, because of the protruding processes and structurally challenging features characterized by uneven and rough surfaces, there is a lack of metric methods for sex estimation, making quantification challenging. In this study, we aimed to validate a derived metric method for sex estimation by reconstructing the nuchal crest region in three-dimensional (3D) images obtained from computed tomography scans of cranial bones and compare its accuracy with that of the nonmetric method. A total of 648 images were collected, with 100 randomly selected for use in the nonmetric method. We applied our metric method to the remaining 548 images. Our findings showed that the surface area of the nuchal crests was greater in male individuals than in female individuals. The nuchal crest surface area quantified by the metric method increased the accuracy of sex estimation by 48% compared with that by the nonmetric method. Our metric method for sex estimation, which quantifies the nuchal crest surface area using 3D images of the skull, led to a high sex estimation accuracy of 93%. Future studies should focus on proposing and quantifying new measurement methods for areas showing sexual characteristics in the skull that are difficult to measure, thereby enhancing the accuracy and reliability of sex estimation in human skeletal identification across various fields.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"535-542"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samad Shahryari, Mohammad Ghasem Hanafi, Rouhangiz Kamankesh, Atefeh Mahdianrad, Ali Reza Eftekhari Moghadam
{"title":"Computed tomographic assessment of the lacrimal sac fossa in southwest population of Iran.","authors":"Samad Shahryari, Mohammad Ghasem Hanafi, Rouhangiz Kamankesh, Atefeh Mahdianrad, Ali Reza Eftekhari Moghadam","doi":"10.5115/acb.22.001E","DOIUrl":"10.5115/acb.22.001E","url":null,"abstract":"","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":"57 4","pages":"625"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142833286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chuan-Xiang Ma, Wei-Ren Pan, Zhi-An Liu, Yao Li, Fan-Qiang Zeng
{"title":"The lymphatic drainage of the goat heart.","authors":"Chuan-Xiang Ma, Wei-Ren Pan, Zhi-An Liu, Yao Li, Fan-Qiang Zeng","doi":"10.5115/acb.24.101","DOIUrl":"10.5115/acb.24.101","url":null,"abstract":"<p><p>The detailed knowledge of the morphological structure, drainage pathways and patterns, the first tier lymph node of the cardiac lymphatic and its relationship with the circulatory system has not yet been completed. Although, the cardiac lymphatics had been described with renewed interest in past years, which was attributed to the transparent nature of lymphatic vessels that are difficult to be observed. In this study, cardiac lymphatics of the goat heart were perfused by a direct microinjecting technique with a radiopaque mixture. This demonstrated the subepicardial and subendocardial lymph capillary networks communicating with transmyocardial lymph vessels and then entering to subepicardial collecting lymph vessels that were directed toward the atrio-ventricular sulcus where they form a confluence from which the main cardiac lymph channels. We also found that: 1) the quantity and caliber of collecting lymph vessels varied in each goat heart; 2) drainage patterns of lymph vessels in the goat heart were different in individuals; 3) the first tier lymph node that each major lymph vessel drained to was different; and 4) multiple lymphatic-venous anastomosis sites have been confirmed to exist in the subepicardium of the left and right ventricles of each goat heart, which may be the morphological structure to accelerate the return of intercellular fluid to the venous system during excessive exercise of the heart. Therefore, the information may provide reference for further study in physiological and pathological conditions of the human heart.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"598-604"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}