Awal M Jimah, Ashley Taylor Goldstein, Melissa McCann, Claire Stoudemire
{"title":"Azygos lobe: exploring the bronchial supply and clinical implications.","authors":"Awal M Jimah, Ashley Taylor Goldstein, Melissa McCann, Claire Stoudemire","doi":"10.5115/acb.24.240","DOIUrl":"10.5115/acb.24.240","url":null,"abstract":"<p><p>An azygos lobe is a rare pulmonary variation that typically presents in the superior lobe of the right lung. Most literature on azygos lobe cases consists of radiologic X-ray or computed tomography findings, with only a few reports based on cadaveric dissections. Here, we report a cadaveric dissection of a right azygos lobe identified in a 77-year-old female anatomical body donor. The azygos lobe was medially located, superior to the hilum, and measured 8.5 cm in length and 4.0 cm in width. The lobe was solely supplied by a subsegmental bronchus from the apical segmental bronchus, which was further divided into two sub-subsegmental bronchial supplies. Prior reports indicate a potential relationship between the azygos lobe and cardiopulmonary pathology or genetic conditions, and further investigation of the bronchial supply may provide insight.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"311-315"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Celia V Mayne, Rarinthorn Samrid, Yoko Tabira, Kazzara Raeburn, Kathleen Bubb, Joe Iwanaga, Samir Anadkat, R Shane Tubbs
{"title":"Variant of the coracohumeralis muscle.","authors":"Celia V Mayne, Rarinthorn Samrid, Yoko Tabira, Kazzara Raeburn, Kathleen Bubb, Joe Iwanaga, Samir Anadkat, R Shane Tubbs","doi":"10.5115/acb.24.184","DOIUrl":"10.5115/acb.24.184","url":null,"abstract":"<p><p>Variant muscles of the cervicobrachial region are relatively uncommon. One rare variant muscle of this region is the cervicohumeralis, which arises from the cervical vertebrae and inserts onto the humerus. During routing dissection of the left neck region, a variant of the cervicohumeralis was identified. Most of the muscle was located in the posterior triangle of the neck but had distal attachments onto the corocoid process of the scapula and the lesser tubercle of the humerus. Such variant muscles are important to consider during image interpretation or surgical procedures in the neck and proximal upper limb. To our knowledge, this is the first case report of an additional attachment of the cervicohumeralis onto the scapula. This variant might be called the cervicoscapulohumeralis muscle and should be distinguished from other muscle variants in this region on medical imaging.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"294-298"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damilare Adedayo Adekomi, John Olabode Fatoki, Titilayo Deborah Adesipe, Omowumi Oyeronke Adewale, Adesina Oloruntoba Adekeye, Temidayo Daniel Adeniyi, Opeyemi Samson Osuntokun, Babatunde Joseph Dare, Lukman Adeayo Yunus, Olumayowa Kolawole Idowu, Ismail Adetayo Lawal, Fatima Omowumi Hamzat
{"title":"Arsenic and vanadium co-exposure induced cerebellar neurotoxicity: aggravates apoptosis, inflammation, oxidative stress, and locomotor deficits in juvenile BALB/c mice.","authors":"Damilare Adedayo Adekomi, John Olabode Fatoki, Titilayo Deborah Adesipe, Omowumi Oyeronke Adewale, Adesina Oloruntoba Adekeye, Temidayo Daniel Adeniyi, Opeyemi Samson Osuntokun, Babatunde Joseph Dare, Lukman Adeayo Yunus, Olumayowa Kolawole Idowu, Ismail Adetayo Lawal, Fatima Omowumi Hamzat","doi":"10.5115/acb.24.116","DOIUrl":"10.5115/acb.24.116","url":null,"abstract":"<p><p>In this research, we studied the individual and combined effects of arsenic and vanadium on the cerebellum of mice. Mice were subjected to arsenic and vanadium individually and in combination for 21 days. Twenty-four hours after the last administration, the mice were subjected to open field and rotarod tests after which the cerebellar tissues were harvested for biochemical analysis of the levels of malondialdehyde (MDA), catalase (CAT), caspase-3, tumor necrosis factor alpha (TNF-α), nuclear factor erythroid 2-related factor 2 (Nrf2), interleukin-1 beta (IL-1β), dopamine, serotonin, acetylcholine, and acetylcholinesterase. The hematoxylin and eosin stain was employed to explore histopathological event in the cerebellar tissue. The mice were either subjected to arsenic or vanadium or their combination showed significant short fall respectively in the open field and rotarod tests. There was an aggravated shortfall in the mice exposed to arsenic+vanadium combination. Furthermore, our data showed that exposure to the combination of arsenic and vanadium provoked synergistic neurotoxicity in the cerebellum of the mice subjected to arsenic+vanadium resulting into disturbance of locomotor and the production of neurodegenerative characteristics in the cerebellum. Relative to the control group, the levels of MDA, CAT, caspase-3, TNF-α, Nrf2, IL-1β, dopamine, serotonin, acetylcholine, and acetylcholinesterase were adversely modulated in the arsenic-treated, vanadium-treated and in the group exposed to the combination of arsenic+vanadium. The histopathology of the cerebellum showed that exposure to arsenic, vanadium, and their combination produced neurodegenerative effects. The study conclude that exposure to arsenic and vanadium, as well as their combination, had a considerable influence on cerebellar tissue, culminating in a synergistic toxic effect.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"229-246"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Age-dependent brain subcortical white and gray matter disruptions in patients with posttraumatic stress disorder.","authors":"Kambiz Kangarlou, Samira Raminfard, Jayran Zebardast, Elham Faghihzadeh, Bahman Jalali Kondori","doi":"10.5115/acb.24.200","DOIUrl":"10.5115/acb.24.200","url":null,"abstract":"<p><p>Posttraumatic stress disorder (PTSD) is a psychiatric condition that can develop after experiencing a traumatic event, and it is associated with a range of functional and structural brain abnormalities. This study aimed to investigate age-related differences in subcortical gray and white matter in veterans with PTSD. This study recruited 44 patients with PTSD and 48 healthy controls. Participants were divided into two age groups to evaluate structural magnetic resonance imaging analysis. The results showed that individuals with PTSD had significantly smaller subcortical gray matter volumes, including the bilateral thalamus, hippocampus, amygdala, left pallidum, and right accumbens-area (<i>P</i><0.05). Diffusion tensor imaging analyses revealed lower fractional anisotropy in several white matter structures, including the anterior limb of the internal capsule, anterior corona radiata, and cingulum in both hemispheres (<i>P</i><0.05). Additionally, the mean diffusivity was higher in the anterior limb of the internal capsule, anterior corona radiata and the right external capsule (<i>P</i><0.05). A comparative analysis between two age groups, over 50 and under 50 years old, showed that younger PTSD patients had a reduction in volume and abnormality in the corresponding white matter in more regions compared to the control group. These findings suggest that PTSD is associated with significant structural alterations in the brain, which may contribute to the pathophysiology of the disorder. So, patient age is an effective factor in exposure to traumatic events and an older age is continuously associated with a worsening traumatic brain injury outcome.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"220-228"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphological analysis of occipital condyle and superior articular facet of first cervical vertebra and its congruence in a Thai population.","authors":"Suchada Treranan, Tawachai Monum, Sukon Prasitwattanaseree, Pasuk Mahakkanukrauh","doi":"10.5115/acb.24.269","DOIUrl":"10.5115/acb.24.269","url":null,"abstract":"<p><p>The atlantooccipital joint, which involves the articulation between the occipital condyles (OC) at the base of the skull and the superior articular facet of the first cervical vertebra (C1), is considered a moderately reliable joint for congruence analysis. Evaluating the congruence of OC and C1 in terms of shape and measurement is critical for re-associating disarticulated cranial and postcranial elements in cases of commingled human remains. This study examined the morphological characteristics and congruence between OC and C1 in a Thai population. A total of 201 OC and C1 samples, including male and female specimens, were analyzed to classify their shapes and measurements. The most common OC shape was oval, while the C1 superior articular facet was predominantly eight-shaped. Males exhibited significantly larger OC and C1 measurements across all variables compared to females. Discriminant analysis showed an accuracy rate of 58.2%-70.1% for sex classification. Pearson's correlation coefficients for OC and C1 measurements ranged from 0.490 to 0.818, with the highest correlation observed for the maximum breadth of OC and C1. Sex-specific analysis revealed that males had the highest correlation for maximum breadth, while females showed the highest correlation for minimum breadth. The regression equation for predicting the paired size of OC and C1 had an accuracy rate of 39%-54.46%. These findings contribute to understanding craniovertebral morphology and have implications for forensic identification and surgical planning at the craniovertebral junction.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"186-199"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatemeh Jameie, Mehdi Dianatpour, Mahintaj Dara, Zahra Jamali, Nasrin Ghorbani, Gökhan Ünal, Mohammad Saied Salehi, Sareh Pandamooz
{"title":"Hair follicle stem cell-derived secretome protects astrocytes in an <i>in vitro</i> ischemia/reperfusion model.","authors":"Fatemeh Jameie, Mehdi Dianatpour, Mahintaj Dara, Zahra Jamali, Nasrin Ghorbani, Gökhan Ünal, Mohammad Saied Salehi, Sareh Pandamooz","doi":"10.5115/acb.24.213","DOIUrl":"10.5115/acb.24.213","url":null,"abstract":"<p><p>Ischemic stroke causes significant neuronal and glial cell damage. Recent studies suggest that stem cell-derived secretomes may offer therapeutic benefits for neural injuries. This study evaluates the protective effects of hair follicle stem cell (HFSC)-derived secretome on astrocytes subjected to oxygen-glucose deprivation (OGD), an <i>in vitro</i> model of ischemic stroke. In this regard, the primary astrocyte cultures were exposed to OGD conditions for 24 hours, followed by treatment with HFSC-derived secretome for 48 hours to create an environment rich in paracrine factors. The neuroprotective effect of HFSC-derived secretome on injured astrocytes was assessed using MTT assay, apoptosis flow cytometry, and qRT-PCR. The HFSC secretome mitigated cell death and apoptosis in OGD-induced astrocytes. Additionally, the secretome reduced the mRNA expression levels of pro-inflammatory cytokines <i>IL-6</i>, <i>IL-1β</i>, and <i>TNF-α</i> compared to the injured cells. Furthermore, it upregulated the mRNA levels of neurotrophic factors <i>BDNF</i>, and <i>VEGF</i> after OGD in astrocytes. These findings suggest that the reparative effects of the secretome are associated with astrocyte neuroprotection, anti-inflammatory properties, and anti-apoptotic effects. The neuroprotective effect of HFSC secretome may be associated with the upregulation of neurotrophic and angiogenic factors. Restored astrocytes create a conducive environment for repair, thereby expediting the recovery of impaired brain function. This study provides preclinical evidence supporting the potential of HFSC secretome in stroke therapy to improve treatment outcomes of patients who suffered from ischemic stroke.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"264-273"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lard is a simple thermo-responsive and environmentally-friendly filler for vascular perfusion in cadaver surgical training.","authors":"Yanhai Zuo, Shouyun Xiao","doi":"10.5115/acb.24.306","DOIUrl":"10.5115/acb.24.306","url":null,"abstract":"<p><p>A good vascular perfusion is vital for the vessel related cadaver surgical training (CST). The objective of this study was to (1) explore the feasibility of using lard as a vascular filler in vascular perfusion in fresh cadavers and (2) explore a simple and environmentally-friendly method for the cadaveric preparation in CST. Ten fresh pig cadavers were employed for separation of lard, and the following vascular perfusion. At about 30°C-40°C, the dye was added to the lard to obtain a satisfactory lard-dye mixture. Thereafter, this mixture was slowly infused into the aorta abdominalis and the lateral saphenous vein. After infusion, the specimens, together with some ice bags, were stored in foam boxes for 3-4 hours. The vascular perfusion of the bones, the muscles, the skin, and the viscus was carefully observed. The lard and the dye mixed well and solidified at 4°C. The time for the cadaveric preparation via this method was approximately 5 hours. The success rate of this method was 100%. Both the arteries and the veins of the bones, the muscles, the skin, and the viscus could be successfully infused at room temperature. Notably, even the capillary network is infused very clearly. After being placed at 0°C-4°C for 3-4 hours, the infused lard solidified. The lard-based vascular injection technique is simple, thermo-responsive and environmentally-friendly. This technique allows CST to be independent of perfusion techniques, equipment, and location.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"166-172"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sareh Pandamooz, Mohammad Ghasemian, Zahra Jamali, Maryam Hassanpour, Mohammad Javad Mokhtari, Shahrokh Zare, Mehdi Dianatpour, Mohammad Reza Jafarzadeh Shirazi, Mohammad Saied Salehi
{"title":"Preconditioning enhances neurotrophic factor expression in rat bone marrow mesenchymal stem cells for neuroregenerative applications.","authors":"Sareh Pandamooz, Mohammad Ghasemian, Zahra Jamali, Maryam Hassanpour, Mohammad Javad Mokhtari, Shahrokh Zare, Mehdi Dianatpour, Mohammad Reza Jafarzadeh Shirazi, Mohammad Saied Salehi","doi":"10.5115/acb.24.289","DOIUrl":"10.5115/acb.24.289","url":null,"abstract":"<p><p>Stroke is a leading cause of mortality and disability in adults worldwide. Among the various treatment strategies, cell-based therapies have gained considerable attention due to their regenerative potential. Enhancing the efficacy of stem cells is critical to improve therapeutic outcomes. Dimethyl fumarate (DMF) is one of the drugs that has been recognized for its ability to modulate the paracrine effects of stem cells. This study aimed to investigate the effect of different concentrations of DMF on rat bone marrow mesenchymal stem cells (BM-MSCs). The BM-MSCs viability following treatment with various doses of DMF was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and fluorescein diacetate staining at 24 and 72 hours. After identifying the optimal DMF concentration, BM-MSCs were cultured with selected DMF concentration for 72 hours, and their gene expression profiles of key neurotrophic factors were analyzed using quantitative real-time polymerase chain reaction. Our findings revealed that 1 μM DMF was the optimal concentration for enhancing BM-MSC viability. Treatment with this dose significantly upregulated the expression of brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3, highlighting their potential in promoting neuronal support and regeneration. In contrast, the transcript level of glial-derived neurotrophic factor was significantly reduced, suggesting a selective regulatory effect of DMF on neurotrophic pathways. These findings shed light on the therapeutic promise of DMF in modulating neurotrophic factor expression in BM-MSCs, offering novel insights into its application in regenerative medicine for neurodegenerative conditions.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"284-293"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chun-Ai Li, Ji Hyun Kim, Zhe-Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shogo Hayashi
{"title":"Ossification of bony nerve canals in the human head: a comparison between the endochondral and membranous bones.","authors":"Chun-Ai Li, Ji Hyun Kim, Zhe-Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shogo Hayashi","doi":"10.5115/acb.24.218","DOIUrl":"10.5115/acb.24.218","url":null,"abstract":"<p><p>Cranial nerves and their branches pass through bony canals in the head. To reveal an ossification manner for closing the nerve canal, we examined histological sections from 32 human fetus heads at 9-18 and 28-40 weeks. Corresponding to types of bones that was penetrated by nerves, the infraorbital nerve (ION) and zygomatic nerve (ZN) were chosen for nerves passing through a membranous bone, while the maxillary nerve (MXN) and hypoglossal nerve (HGN) were chosen for nerves through the endochondral bone. The ION and ZN were sandwiched by membranous bones. The membranous bone trabeculae connected to the secondarily-developed periosteal bone and the latter partly closed the ION canal prenatally, but the closure of the ZN canal was most likely to occur postnatally. Therefore, rather than membranous bone trabeculae, the periosteal bone contributed much to closure of the nerve canal. Because it connected to the periosteum, the orbital muscle might provide a mechanical load facilitating the ossification around the ION. The MXN first passed through the cartilaginous sphenoid and, later, the perichondral bone appeared along the nerve in combination with the additional membranous ossification. Near the HGN canal, a small center of endochondral ossification appeared and the secondarily-developed bone reached the perichondrium of the canal, but the typical periosteal ossification was absent. Consequently, the perichondral or periosteal ossification along the nerve canal seemed to play a major role for a complete closure of the canal postnatally. Modern radiology might show the canal much thicker than the nerve itself in infants.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"210-219"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xander du Plooy, Yuki Kunisada, Juan J Cardona, Yoko Tabira, Kathleen Carol Bubb, Kazzara Raeburn, Soichiro Ibaragi, Joe Iwanaga, R Shane Tubbs
{"title":"The trochlea for the intermediate tendon of the digastric muscle: a review.","authors":"Xander du Plooy, Yuki Kunisada, Juan J Cardona, Yoko Tabira, Kathleen Carol Bubb, Kazzara Raeburn, Soichiro Ibaragi, Joe Iwanaga, R Shane Tubbs","doi":"10.5115/acb.24.178","DOIUrl":"10.5115/acb.24.178","url":null,"abstract":"<p><p>This review explores the novel perspective that the intermediate tendon of the digastric muscle may function as an anatomical trochlear pulley system within the human body, challenging the traditional understanding of trochlear systems. While widely recognized trochlear units include structures like the medial part of the humerus and the superior oblique muscle of the orbit, the review focuses on the unique anatomical arrangement of the intermediate tendon of the digastric muscle in connection with the anterior and posterior bellies of the digastric muscles. Despite current debates within the anatomical community about labeling the digastric muscles as having a trochlea, this paper delves into the scientific definition of a trochlear pulley system, presenting the intermediate tendon of the digastric muscle as a potential trochlea.</p>","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"145-148"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}