Anatomy & Cell Biology最新文献_第3页

Lard is a simple thermo-responsive and environmentally-friendly filler for vascular perfusion in cadaver surgical training. 猪油是一种简单的热反应性和环境友好的填充物，用于尸体手术训练中的血管灌注。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-03-18 DOI: 10.5115/acb.24.306

Yanhai Zuo, Shouyun Xiao

{"title":"Lard is a simple thermo-responsive and environmentally-friendly filler for vascular perfusion in cadaver surgical training.","authors":"Yanhai Zuo, Shouyun Xiao","doi":"10.5115/acb.24.306","DOIUrl":"10.5115/acb.24.306","url":null,"abstract":"A good vascular perfusion is vital for the vessel related cadaver surgical training (CST). The objective of this study was to (1) explore the feasibility of using lard as a vascular filler in vascular perfusion in fresh cadavers and (2) explore a simple and environmentally-friendly method for the cadaveric preparation in CST. Ten fresh pig cadavers were employed for separation of lard, and the following vascular perfusion. At about 30°C-40°C, the dye was added to the lard to obtain a satisfactory lard-dye mixture. Thereafter, this mixture was slowly infused into the aorta abdominalis and the lateral saphenous vein. After infusion, the specimens, together with some ice bags, were stored in foam boxes for 3-4 hours. The vascular perfusion of the bones, the muscles, the skin, and the viscus was carefully observed. The lard and the dye mixed well and solidified at 4°C. The time for the cadaveric preparation via this method was approximately 5 hours. The success rate of this method was 100%. Both the arteries and the veins of the bones, the muscles, the skin, and the viscus could be successfully infused at room temperature. Notably, even the capillary network is infused very clearly. After being placed at 0°C-4°C for 3-4 hours, the infused lard solidified. The lard-based vascular injection technique is simple, thermo-responsive and environmentally-friendly. This technique allows CST to be independent of perfusion techniques, equipment, and location.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"166-172"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preconditioning enhances neurotrophic factor expression in rat bone marrow mesenchymal stem cells for neuroregenerative applications. 预处理增强大鼠骨髓间充质干细胞中神经营养因子的表达，用于神经再生。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-04-08 DOI: 10.5115/acb.24.289

Sareh Pandamooz, Mohammad Ghasemian, Zahra Jamali, Maryam Hassanpour, Mohammad Javad Mokhtari, Shahrokh Zare, Mehdi Dianatpour, Mohammad Reza Jafarzadeh Shirazi, Mohammad Saied Salehi

{"title":"Preconditioning enhances neurotrophic factor expression in rat bone marrow mesenchymal stem cells for neuroregenerative applications.","authors":"Sareh Pandamooz, Mohammad Ghasemian, Zahra Jamali, Maryam Hassanpour, Mohammad Javad Mokhtari, Shahrokh Zare, Mehdi Dianatpour, Mohammad Reza Jafarzadeh Shirazi, Mohammad Saied Salehi","doi":"10.5115/acb.24.289","DOIUrl":"10.5115/acb.24.289","url":null,"abstract":"Stroke is a leading cause of mortality and disability in adults worldwide. Among the various treatment strategies, cell-based therapies have gained considerable attention due to their regenerative potential. Enhancing the efficacy of stem cells is critical to improve therapeutic outcomes. Dimethyl fumarate (DMF) is one of the drugs that has been recognized for its ability to modulate the paracrine effects of stem cells. This study aimed to investigate the effect of different concentrations of DMF on rat bone marrow mesenchymal stem cells (BM-MSCs). The BM-MSCs viability following treatment with various doses of DMF was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and fluorescein diacetate staining at 24 and 72 hours. After identifying the optimal DMF concentration, BM-MSCs were cultured with selected DMF concentration for 72 hours, and their gene expression profiles of key neurotrophic factors were analyzed using quantitative real-time polymerase chain reaction. Our findings revealed that 1 μM DMF was the optimal concentration for enhancing BM-MSC viability. Treatment with this dose significantly upregulated the expression of brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3, highlighting their potential in promoting neuronal support and regeneration. In contrast, the transcript level of glial-derived neurotrophic factor was significantly reduced, suggesting a selective regulatory effect of DMF on neurotrophic pathways. These findings shed light on the therapeutic promise of DMF in modulating neurotrophic factor expression in BM-MSCs, offering novel insights into its application in regenerative medicine for neurodegenerative conditions.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"284-293"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ossification of bony nerve canals in the human head: a comparison between the endochondral and membranous bones. 人头部骨神经管的骨化：软骨内骨与膜性骨的比较。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-03-18 DOI: 10.5115/acb.24.218

Chun-Ai Li, Ji Hyun Kim, Zhe-Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shogo Hayashi

{"title":"Ossification of bony nerve canals in the human head: a comparison between the endochondral and membranous bones.","authors":"Chun-Ai Li, Ji Hyun Kim, Zhe-Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shogo Hayashi","doi":"10.5115/acb.24.218","DOIUrl":"10.5115/acb.24.218","url":null,"abstract":"Cranial nerves and their branches pass through bony canals in the head. To reveal an ossification manner for closing the nerve canal, we examined histological sections from 32 human fetus heads at 9-18 and 28-40 weeks. Corresponding to types of bones that was penetrated by nerves, the infraorbital nerve (ION) and zygomatic nerve (ZN) were chosen for nerves passing through a membranous bone, while the maxillary nerve (MXN) and hypoglossal nerve (HGN) were chosen for nerves through the endochondral bone. The ION and ZN were sandwiched by membranous bones. The membranous bone trabeculae connected to the secondarily-developed periosteal bone and the latter partly closed the ION canal prenatally, but the closure of the ZN canal was most likely to occur postnatally. Therefore, rather than membranous bone trabeculae, the periosteal bone contributed much to closure of the nerve canal. Because it connected to the periosteum, the orbital muscle might provide a mechanical load facilitating the ossification around the ION. The MXN first passed through the cartilaginous sphenoid and, later, the perichondral bone appeared along the nerve in combination with the additional membranous ossification. Near the HGN canal, a small center of endochondral ossification appeared and the secondarily-developed bone reached the perichondrium of the canal, but the typical periosteal ossification was absent. Consequently, the perichondral or periosteal ossification along the nerve canal seemed to play a major role for a complete closure of the canal postnatally. Modern radiology might show the canal much thicker than the nerve itself in infants.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"210-219"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The trochlea for the intermediate tendon of the digastric muscle: a review. 二腹肌中间肌腱的滑车：综述。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-01-15 DOI: 10.5115/acb.24.178

Xander du Plooy, Yuki Kunisada, Juan J Cardona, Yoko Tabira, Kathleen Carol Bubb, Kazzara Raeburn, Soichiro Ibaragi, Joe Iwanaga, R Shane Tubbs

引用次数: 0

A Y-shaped sphenoidal sinus septum: a case report. y型蝶窦中隔1例。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-01-23 DOI: 10.5115/acb.24.284

Rarinthorn Samrid, Joanna Jaworek-Troć, Tomasz Gładysz, Jerzy A Walocha, Joe Iwanaga, R Shane Tubbs

引用次数: 0

Surgical anatomy of the anterior musculocapsular complex of the hip: a macroscopic and microscopic anatomical reappraisal. 髋关节前肌囊复合体的外科解剖：宏观和微观解剖的重新评估。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-04-08 DOI: 10.5115/acb.24.329

Michal Benes, Vladislav Bartak, Jiri Uhlik, Tomas Novotny, Aneta Rybakova, David Kachlik, Vojtech Kunc

{"title":"Surgical anatomy of the anterior musculocapsular complex of the hip: a macroscopic and microscopic anatomical reappraisal.","authors":"Michal Benes, Vladislav Bartak, Jiri Uhlik, Tomas Novotny, Aneta Rybakova, David Kachlik, Vojtech Kunc","doi":"10.5115/acb.24.329","DOIUrl":"10.5115/acb.24.329","url":null,"abstract":"This study aimed to delineate the macroscopic and microscopic topography of muscles surrounding the anterior aspect of the hip joint and the underlaying joint capsule. Seven fresh-frozen cadavers were bilaterally dissected as per study protocol. Eleven hip joints were evaluated macroscopically, while three hip joints underwent histological analysis. Additionally, twenty hip bones and femurs were examined for the osseous morphology near the anterior portion of the articulating surfaces. Macroscopically, the rectus femoris muscle contributed to the articular capsule exclusively through its reflected head. The iliocapsularis and iliopsoas muscles were in direct contact with the articular capsule. Although the iliocapsularis muscle was adherent to the capsule throughout its whole course, the iliopsoas muscle was connected to the capsule through the iliopectineal bursa. Microscopically, different spatial thickness of the capsule was observed, with the thicker regions corresponding to the capsular ligaments. Osseous landmarks, relevant to the course of the iliopsoas muscle, included the iliopsoas notch and a groove for the psoas major muscle. Furthermore, split of the anterior inferior iliac spine and the \"subspine\" were constant findings corresponding to the origin of the direct head of the rectus femoris and the iliocapsularis muscles, and attachment of the medial band of the iliofemoral ligament, respectively. On the head of the femur, the Poirier's facet (35.0%), the Allen's fossa (60.0%), and the so-called plaque (50.0%) were observed. Conclusively, we introduce the concept of a four-layered anterior musculocapsular complex of the hip, aiming to aid the orthopaedic surgeon in both hip replacement and preservation procedures.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"155-165"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reliability of Sedillot's triangle as a potential anatomical landmark for central venous catheter insertion: insights from cadaveric study. Sedillot三角形作为中心静脉导管插入的潜在解剖学标志的可靠性：来自尸体研究的见解。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-30 Epub Date: 2025-03-05 DOI: 10.5115/acb.24.271

Apurba Patra, Anju Chaudhary, Adil Asghar, Priti Chaudhary

{"title":"Reliability of Sedillot's triangle as a potential anatomical landmark for central venous catheter insertion: insights from cadaveric study.","authors":"Apurba Patra, Anju Chaudhary, Adil Asghar, Priti Chaudhary","doi":"10.5115/acb.24.271","DOIUrl":"10.5115/acb.24.271","url":null,"abstract":"Sedillot's triangle (ST), formed between the sternal and clavicular heads of sternocleidomastoid (SCM) muscle, is often used as an anatomical landmark for internal jugular vein (IJV) cannulation, but its reliability has been questioned. This cadaveric study aimed to evaluate the effectiveness of ST in locating IJV. Dissections were performed on 23 adult cadavers (46 sides). ST was exposed, and a pin was inserted at its apex to assess its relationship with IJV. Dimensions of ST and distance between apex and IJV were measured (only in cases with unsuccessful puncture), along with IJV diameter at the apex. Showed that 92.00% of sides had a fully formed ST, while 8.00% (all left-sided) lacked a gap between the SCM heads. On right side, the needle corresponded directly with IJV in 19 (82.60%) cases, but missed laterally and medially in two (8.69%) cases each. On left side, successful IJV puncture occurred in 11 (61.11%) cases, with lateral and medial misses in five (27.77%) and two (11.11%) respectively. The mean height and width of ST was 64.30±7.86 mm and 20.08±6.26 mm on right side and 63.95±7.28 mm and 15.56±9.91 mm on left side. IJV diameter at the apex was significantly higher in male and on right side. Overall, right ST proved to be a reasonably reliable landmark for successful central venous catheter. However, anatomical variability, particularly on left side, suggests that caution should be exercised, and additional methods such as ultrasound guidance may improve the accuracy and safety of IJV cannulation using this approach.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"149-154"},"PeriodicalIF":1.4,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with osteophytosis on the sella turcica: related morphological and morphometrical aspects. 蝶鞍骨赘病的相关因素：相关形态学和形态计量学方面。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-24 DOI: 10.5115/acb.25.080

David Ezra, R Shane Tubbs, Joe Iwanaga, Deborah Alperovitch-Najenson, Arthur Yosef, Israel Hershkovitz, James Cray

{"title":"Factors associated with osteophytosis on the sella turcica: related morphological and morphometrical aspects.","authors":"David Ezra, R Shane Tubbs, Joe Iwanaga, Deborah Alperovitch-Najenson, Arthur Yosef, Israel Hershkovitz, James Cray","doi":"10.5115/acb.25.080","DOIUrl":"https://doi.org/10.5115/acb.25.080","url":null,"abstract":"The sella turcica, part of the sphenoid bone located at the base of the skull, is associated with multiple important neurovascular structures. Hence, a detailed knowledge of its variations is critical to clinicians who interpret imaging or surgeons who operate in this region. Our aim was to better understand the pathology of osteophytosis, often found related to the sella turcica. The study sample (n=1,083, human skulls) was obtained from the skeleton collection housed in the Natural History Museum, Cleveland, OH, USA. All skulls were assessed for osteophytes in the sella turcica region (defined as an overgrowth of 1 mm or more). Morphometrical measurements included skull length, width, and thickness, correlated to seller osteophytes. Cranial shape was related to the presence of osteophytes. Greater prevalence was seen in the brachycephalic skulls, with a significantly higher ratio of presence in older people (79.6%) compared to a younger population (26.4%); greater prevalence was also observed in female skulls with a composite thickness of the frontal, parietal and occipital bones. A multifactorial analysis using a logistic regression model defined a statistically significant model, by explaining 37.0% of the variance in osteophyte presence and correctly classifying 77.2% of the cases. Female skulls were 1.76 times more likely to display osteophytes of the sella turcica. Increasing age and increased skull thickness were associated with an enhanced likelihood of exhibiting osteophytes involving the sella turcica, thereby, the shape of the skull, age, and sex partially explain the variations observed for the presence of sella turcica osteophytes.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The maxillary vein: an anatomical narrative review with clinical implications for oral and maxillofacial surgeons. 上颌静脉：口腔颌面外科的临床意义解剖叙述回顾。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-09 DOI: 10.5115/acb.25.024

Kazzara Raeburn, Yohei Takeshita, Hiroaki Takakura, Shogo Kikuta, Yuki Kunisada, Soichiro Ibaragi, Rarinthorn Samrid, Marios Loukas, R Shane Tubbs, Joe Iwanaga

{"title":"The maxillary vein: an anatomical narrative review with clinical implications for oral and maxillofacial surgeons.","authors":"Kazzara Raeburn, Yohei Takeshita, Hiroaki Takakura, Shogo Kikuta, Yuki Kunisada, Soichiro Ibaragi, Rarinthorn Samrid, Marios Loukas, R Shane Tubbs, Joe Iwanaga","doi":"10.5115/acb.25.024","DOIUrl":"https://doi.org/10.5115/acb.25.024","url":null,"abstract":"The maxillary vein, despite its clinical significance, remains underexplored in anatomical literature. It plays a crucial role in venous drainage of the maxillofacial region and is closely associated with surgical procedures such as sagittal split ramus osteotomy, mandibuloplasty, and condylar or parotid surgeries. Due to its variable anatomy and proximity to critical structures, the maxillary vein poses a risk of significant hemorrhage if injured. Its small size and deep location make preoperative identification challenging, especially without contrast-enhanced imaging. Embryologically, the maxillary vein originates from the primitive maxillary vein and develops through complex anastomoses with other craniofacial veins. Anatomical studies have revealed several variations, including the presence of accessory mandibular foramina and unusual venous connections, which may increase surgical risk. Understanding the detailed anatomy and potential variations of the maxillary vein is essential for minimizing complications and improving surgical outcomes. Despite its importance, more anatomical and clinical research is needed to better define its course, variations, and implications in oral and maxillofacial surgery.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating relation terms and comparison in Terminologia Anatomica: a study on supreme. 《解剖学术语》中关系术语的评价与比较——以supreme为例。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-04 DOI: 10.5115/acb.25.056

Laura García-Orozco, Jhonatan Duque-Colorado, Mariano Del Sol

{"title":"Evaluating relation terms and comparison in Terminologia Anatomica: a study on supreme.","authors":"Laura García-Orozco, Jhonatan Duque-Colorado, Mariano Del Sol","doi":"10.5115/acb.25.056","DOIUrl":"https://doi.org/10.5115/acb.25.056","url":null,"abstract":"The terms of relationship and comparison, which consist of 44 elements grouped as general terms in Terminologia Anatomica, describe the location of anatomical structures and facilitate communication between health professionals and students. During a review in Terminologia Anatomica, the term 'supreme' was found in various structures. However, it is not part of the general terms, which could create confusion when describing and comparing anatomical structures. For this reason, this study aimed to analyze the relevance of supreme and its possible relationship with the superior term. A review of Terminologia Anatomica was conducted to identify structures designated by the adjective \"supreme\" or its Latin equivalent, suprema. The term was then categorized based on anatomical context. An etymological analysis of supreme and superior revealed that both terms stem from the Latin root super, meaning above or over. However, over time, each term evolved with distinct meanings. In Terminologia Anatomica, 'superior' is used as a comparative adjective for a higher position relative to another structure. 'Supreme' is a superlative adjective that indicates the highest level and the designation of structures in a principal position relative to others. Due to inconsistent usage, we suggest including 'supreme' in Terminologia Anatomica and unifying its application. Specifically, it should be limited to structures where terms such as superior, middle, and inferior are applied and when describing structures that occupy a principal position relative to others. In this sense, we suggest changing the supreme, superior and inferior nuchal lines to superior, middle and inferior nuchal lines, respectively.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0