Anatomy & Cell Biology最新文献_第4页

A potential interference of chemoreception in inflamed vomeronasal organ with experimental autoimmune encephalomyelitis. 实验性自身免疫性脑脊髓炎炎症的犁鼻器官化疗接受的潜在干扰

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-05-23 DOI: 10.5115/acb.25.020

Kyungsook Jung, Deokho Ko, Sungmoo Hong, Irene Ortiz-Leal, Pablo Sanchez-Quinteiro, Meejung Ahn, Changjong Moon, Taeyoung Kang, Taekyun Shin, Jeongtae Kim

引用次数: 0

Anatomical variations of the infrahyoid muscles and ansa cervicalis: a systematic review and an updated classification system for the omohyoid muscle. 舌骨下肌和颈袢的解剖变异：对肩胛舌骨肌的系统回顾和更新的分类系统。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.307

Nymfodora Malkidou, Vasileios Papadopoulos, Aliki Fiska

{"title":"Anatomical variations of the infrahyoid muscles and ansa cervicalis: a systematic review and an updated classification system for the omohyoid muscle.","authors":"Nymfodora Malkidou, Vasileios Papadopoulos, Aliki Fiska","doi":"10.5115/acb.24.307","DOIUrl":"https://doi.org/10.5115/acb.24.307","url":null,"abstract":"The four infrahyoid muscles of the anterior neck are primarily innervated by the ansa cervicalis. This systematic review aims to evaluate the range of the anatomical variations in these muscles and their relationship to innervation patterns. A systematic search was conducted using PubMed and Google Scholar databases. Articles reporting variations in infrahyoid muscles and/or ansa cervicalis were independently evaluated following the PICOTS framework. The anatomical quality assessment tool was used to assess the quality of publications reporting anatomical variants. Seventy-seven studies, encompassing eighty-four cases, were included in the analysis. Of the 56-publication reporting infrahyoid muscle variations, 44 pertained to the omohyoid muscle (main or accessory), 3 to the sternohyoid, 4 to the sternothyroid, and 1 to the thyrohyoid, with no accessory variation observed in the latter. Atypical infrahyoid muscles were identified in 11 cases, 9 of which presented as levator glandulae thyroideae, and 2 as single cases. Variations in the ansa cervicalis were documented in 29 cases, only 1 case involved both ansa cervicalis and infrahyoid muscle variations. The extensive variability of the omohyoid muscle led to the development of a new classification system that integrates 4 types of consistency and 4 types of morphometric variations, providing valuable insights for clinical practice. The specialized use of the infrahyoid muscles in cancer staging, reconstruction after neck cancer surgery, and thyroid surgery underscores the need for a new framework to document their variations, particularly in the omohyoid muscle.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aberrant rib cage anatomy with false ribs attachment to the sternum: review of the literature focused on slipping ribs syndrome case reports. 异常胸腔解剖与假肋骨附着于胸骨：文献回顾侧重于肋骨滑移综合征病例报告。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.227

Sayed Mehrdad Azimi, Fateme Keshtparvar, Zahra Sadeghi, Hamid Bahramian

{"title":"Aberrant rib cage anatomy with false ribs attachment to the sternum: review of the literature focused on slipping ribs syndrome case reports.","authors":"Sayed Mehrdad Azimi, Fateme Keshtparvar, Zahra Sadeghi, Hamid Bahramian","doi":"10.5115/acb.24.227","DOIUrl":"https://doi.org/10.5115/acb.24.227","url":null,"abstract":"The thoracic cage, formed by ribs and sternum, protects vital organs while enabling respiration. This review examines anatomical variations in rib-sternum attachments and their clinical significance through analysis of literature from 1993-2023. Variations, including bifid ribs (0.15%-3.4% prevalence) and cervical ribs (0.05%-3.0%), can lead to conditions like slipping rib syndrome (SRS). An extensive search of PubMed, Embase, Google Scholar, Web of Science, and specialized collections identified 17 comprehensive SRS case reports. Two independent reviewers evaluated these cases, revealing that rib-sternum morphological variations significantly impact respiratory biomechanics, with unstable costal cartilage identified as a primary cause of pain syndromes. These findings highlight the critical importance of recognizing aberrant rib-sternum anatomy for patient safety, particularly in thoracic procedures. Advanced imaging technologies have enhanced detection capabilities, allowing for improved surgical planning and patient management. This review underscores the value of both cadaveric and radiological examination in identifying these variations, and recommends further research to clarify their prevalence, functional implications, and clinical correlations to optimize treatment approaches and outcomes.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenging arterial patterns of renal and testicular arteries in a human cadaver: clinical significance and embryological bases revisited. 具有挑战性的人尸体肾和睾丸动脉的动脉模式：临床意义和胚胎学基础重新审视。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.336

Wenshao Cai, Minyan Shi, David W Chan, Baohua Luo, Abudureyimujiang Ruze

引用次数: 0

Histomorphogenesis of human pancreatic islets amidst maternal anaemia: a critical insight. 人胰岛在母体贫血中的组织形态发生：一个关键的见解。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-23 DOI: 10.5115/acb.24.274

Sruthy Babu, Pravash Ranjan Mishra, Praveen Kumar Ravi, Sashikanta Swain, Jasmina Begum, Madhumita Patnaik

{"title":"Histomorphogenesis of human pancreatic islets amidst maternal anaemia: a critical insight.","authors":"Sruthy Babu, Pravash Ranjan Mishra, Praveen Kumar Ravi, Sashikanta Swain, Jasmina Begum, Madhumita Patnaik","doi":"10.5115/acb.24.274","DOIUrl":"https://doi.org/10.5115/acb.24.274","url":null,"abstract":"Maternal anaemia, the most common nutritional deficiency, adversely affects the growth and development of the fetus as a whole and the fetal pancreas in particular. These changes lead to the young onset of diabetes in the near future. To understand the pathophysiology behind this, present study investigates the histomorphogenesis of human fetal pancreatic islets and the impact of maternal anaemia on islet dimension, area proportion, and cellular composition across various gestational weeks using immunohistochemistry. The research was conducted on 18 human fetal pancreases obtained from spontaneous abortions or stillbirths between 17 to 36 weeks of gestation, categorized into normal (n=10) and anaemic (n=8) maternal groups. Results revealed a larger islet diameter in fetuses from anaemic mothers compared to the non-anaemic group (P=0.039). The beta cell percentage was significantly lower in the anaemic group across all gestational ages (P=0.003), while the alpha cell proportion remained unchanged in the anaemic group but increased significantly in the non-anaemic group after 20 weeks (P=0.006). The non-alpha/beta cell proportion in anaemic group was consistently higher than in the non-anaemic group. In conclusion, maternal anaemia results in the reprogramming of fetal pancreatic islets, characterized by a reduction in beta cell proportion, an increase in non-alpha/beta cells, and a disruption in the alpha-to-beta cell ratio. These changes may impair fetal pancreatic function and predispose the offspring to glucose intolerance and diabetes in later life. Ensuring adequate maternal nutrition through iron and folic acid supplementation during pregnancy is essential to prevent these developmental disruptions.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of Chlorella vulgaris against experimental hepatic ischemia reperfusion injury downregulating oxidative stress, inflammation, and apoptosis. 下调氧化应激、炎症和细胞凋亡的小球藻对实验性肝缺血再灌注损伤的保护作用

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-23 DOI: 10.5115/acb.24.318

Amira E Farage, Mona A Abdel-Kareem, Medhat Taha, Sara Abubakr, Nora Elshehawy Helal, Mahmoud Hendawy, Hanan A Elgendy, Ahmed Abdel-Monem Elmetwally, Hala Mahfouz, Tourki A S Baokbah, Mohammed R Rabei, Mohammad Akbar Hossain, Azza I Helal, Mohie Mahmoud Ibrahim

{"title":"Protective effect of Chlorella vulgaris against experimental hepatic ischemia reperfusion injury downregulating oxidative stress, inflammation, and apoptosis.","authors":"Amira E Farage, Mona A Abdel-Kareem, Medhat Taha, Sara Abubakr, Nora Elshehawy Helal, Mahmoud Hendawy, Hanan A Elgendy, Ahmed Abdel-Monem Elmetwally, Hala Mahfouz, Tourki A S Baokbah, Mohammed R Rabei, Mohammad Akbar Hossain, Azza I Helal, Mohie Mahmoud Ibrahim","doi":"10.5115/acb.24.318","DOIUrl":"https://doi.org/10.5115/acb.24.318","url":null,"abstract":"Hepatic ischemia/reperfusion (Hep I/R) is a great health burden during hepatic transplantation surgery. The present work aimed to examine the mitigative effect of Chlorella vulgaris against Hep I/R and its underlying protective mechanisms. The animals in the present research were classified into four equal experimental groups (n=6): the sham group, sham+Chlorella vulgaris group, Hep I/R group, and Hep I/R+Chlorella vulgaris group. Hepatic ischemia results in liver impairment, as evidenced by elevated liver enzyme levels and altered liver histology. It also reduced antioxidant enzyme levels and increased lipid peroxidation. Additionally, the Hep I/R group displayed significant suppression of the nuclear factor erythroid 2-related factor 2 (Nrf2)/haem oxygenase-1 pathway. There was a marked elevation in the expression of inflammatory markers, including nuclear factor kappa beta (NF-κB), tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6, and myloperoxidase, and NOD-like receptor protein 3 (NLRP3) and caspase-1. Furthermore, the levels of apoptotic markers such as caspase-3 and Bax were greater than those in the sham groups. Pretreatment with Chlorella vulgaris significantly protected against Hep I/R by reversing these effects. Rats pretreated with Chlorella vulgaris exhibited a hepatoprotective effect against Hep I/R through its inhibition of the NF-κB and NLRP3 cascades and Nrf2 stimulation.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Absent right superior vena cava and persistent left superior vena cava opening into the left auricle with transposition of the azygos system of veins. 右上腔静脉缺失，左上腔静脉持续存在，进入左耳廓，静脉奇静脉系统移位。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-10 DOI: 10.5115/acb.24.255

Nanditha Pavikuttan, Kshema Jose, Minnie Pillay

引用次数: 0

Evaluation of gibberellic acid toxicity on pre and postnatal ovarian development and potential protective effect of selenium in albino rats: histological, immunohistochemical, and biochemical study. 赤霉素酸对白化病大鼠出生前后卵巢发育的毒性及硒的潜在保护作用：组织学、免疫组织化学和生化研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-08 DOI: 10.5115/acb.24.305

Shimaa A Fareed, Amira El Sayed Farag, Eman M Kamel Elshireef

{"title":"Evaluation of gibberellic acid toxicity on pre and postnatal ovarian development and potential protective effect of selenium in albino rats: histological, immunohistochemical, and biochemical study.","authors":"Shimaa A Fareed, Amira El Sayed Farag, Eman M Kamel Elshireef","doi":"10.5115/acb.24.305","DOIUrl":"https://doi.org/10.5115/acb.24.305","url":null,"abstract":"Gibberellic acid (GA3) is a biocide with insecticidal properties. Selenium (Se) has an enzymatic structure that mediates its antioxidant activities. This study aimed to assess the GA3 toxicity on pre and postnatal ovarian development and to investigate the protective effect of Se against GA3 toxicity in albino rats. Two experiments were conducted in this study (n=24 rats for each): the first was performed on pregnant female rats and the second on prepubertal females (4 weeks old). Rats were divided into Group I (controls: Ia, negative and Ib, positive rats received sodium selenite 0.3 mg/kg/body weight); Group II (GA3-treated, the rats received 55 mg/kg, 1/100 of lethal dose 50); and Group III (the rats were cotreated with GA3 plus Se). Treatments in the first experiment began at gestational day 7 until postnatal day 4, while in the second experiment, treatments lasted two weeks. All hormonal levels were decreased in pre and postnatal GA3 rats' exposure. Histological examination of GA3-treated prenatal rats showed disturbance in ovarian development as shown by ovigerous cords with germ cell breakdown. Meanwhile, multiple histopathological and developmental changes occur in all stages of the ovarian follicles in postnatal rats. In both developmental ages, there was collagen deposition with decreased proliferative marker and androgen receptor expressions, which was confirmed by a decrease in the morphometric measures of the ovarian follicles. All biochemical, immunostaining, and histological results were improved after Se co-administration due to its antioxidant activity against GA3 toxicity.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of gestational diabetes mellitus and its management on the histological and histomorphometric structure of umbilical cord: a comparative study. 妊娠期糖尿病及其治疗对脐带组织学和组织形态学结构的影响：一项比较研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-03-31 Epub Date: 2025-02-05 DOI: 10.5115/acb.24.179

Seema Valsalan Ennazhiyil, Akshara Venmalassery Rajeev, Mahesh Kumar Damodaran, Tintu Thottiyil Sukumaran, Chitra Srinivasan, Ramakrishnan Panicker Kunnathu

{"title":"Effect of gestational diabetes mellitus and its management on the histological and histomorphometric structure of umbilical cord: a comparative study.","authors":"Seema Valsalan Ennazhiyil, Akshara Venmalassery Rajeev, Mahesh Kumar Damodaran, Tintu Thottiyil Sukumaran, Chitra Srinivasan, Ramakrishnan Panicker Kunnathu","doi":"10.5115/acb.24.179","DOIUrl":"10.5115/acb.24.179","url":null,"abstract":"The umbilical cord lacks vasavasorum and is prone for hypoxic injuries. Gestational diabetes mellitus (GDM) causes structural changes with in umbilical cord blood vessels. Knowledge of which would be helpful for the gynecologist and obstetricians to assess the prognosis and prevent the complications. The present study was concentrated from December 2016 to December 2019 on 50 normal and 56 GDM umbilical cords. GDM group included 23 GDM mothers managed by diet (GDM-Diet) and 33 GDM mothers managed by drugs (GDM-Drug). Placentas along with the attached umbilical cords were collected and stored in 10% formaline. Tissue processing, slide preparation and stainings were done using standard protocols. A significant reduction was observed in the number of Hoboken nodules of umbilical arteries of GDM-Diet. Reduction of myofibroblasts with an increase in the empty spaces was observed in the Wharton's jelly of both GDM cases. Similarly, smooth muscle disintegration and migration of smooth muscles to intima was significantly higher in GDM umbilical arteries and veins than normal umbilical vessels. The total wall thickness and tunica media was significantly thicker in the umbilical arteries of GDM-Drug group only. The umbilical venous lumen was found significantly wider in GDM groups compared to normal. The elastin fibers were significantly found reduced in the tunics of umbilical arteries and veins in GDM. However, a significant difference in these parameters was not observed between the GDM-Diet and GDM-Drug groups except for total wall and tunica media thickness of umbilical arteries.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"22-34"},"PeriodicalIF":1.4,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cost-effectiveness and other considerations for different research techniques applied in ancient DNA analysis. 古 DNA 分析中应用的不同研究技术的成本效益及其他考虑因素。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-03-31 Epub Date: 2024-11-06 DOI: 10.5115/acb.24.125

Jong Ha Hong, Hisashi Fujita, Jaehyup Kim, Dong Hoon Shin

引用次数: 0