Anatomy & Cell Biology最新文献_第4页

Anatomical variations of the hepatic veins: an observational study from a single cadaveric lab in South India. 肝静脉的解剖变异：来自南印度单一尸体实验室的观察性研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-04 DOI: 10.5115/acb.24.258

Rajaneesh Shivamurthy Tolahunase, Pauline Shanthi, Suganthy Rabi

{"title":"Anatomical variations of the hepatic veins: an observational study from a single cadaveric lab in South India.","authors":"Rajaneesh Shivamurthy Tolahunase, Pauline Shanthi, Suganthy Rabi","doi":"10.5115/acb.24.258","DOIUrl":"https://doi.org/10.5115/acb.24.258","url":null,"abstract":"Modern hepatic resections need to consider hepatic vein variations to reduce surgical complications. In this study we determined the variation in the branching pattern of hepatic veins by modified luminal casting technique and evaluated the association of the hepatic vein variations with morphological variations of the liver. The morphological features of thirty formalin-fixed livers were noted. The branching pattern of the hepatic veins was studied by retrograde injection of silicone into the hepatic veins through the inferior vena cava. According to the descriptions given by previous studies, the right, middle, left hepatic veins, and combined middle and left hepatic venous branching patterns were categorized. The data was analyzed statistically. The predominant hepatic vein patterns were De Cecchis type I right hepatic vein (30%), Neumann type I middle hepatic vein (67%), and Reichert type I left hepatic vein (70%). A common trunk for the middle and left hepatic vein was present in 60% and Wind's type II was more common (30%) followed by type I (20%) and type III (10%). While there was no association between the De Cecchis and Wind types, 90% of the conical-shaped livers exhibited type II middle/left hepatic vein pattern of Wind's classification. The present study also observed a rare variation of an accessory inferior left hepatic vein.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological changes and inflammatory and cell death pathways in the lungs of Balb/c mice with pneumonia induced by different concentrations of Staphylococcus aureus. 不同浓度金黄色葡萄球菌致Balb/c小鼠肺炎的组织病理学改变及炎症和细胞死亡途径

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-04 DOI: 10.5115/acb.24.304

Celso Eduardo Silva Fortunato, Renata Pereira Alves, Karinne Spirandelli Carvalho Naves, Monica Cassel

{"title":"Histopathological changes and inflammatory and cell death pathways in the lungs of Balb/c mice with pneumonia induced by different concentrations of Staphylococcus aureus.","authors":"Celso Eduardo Silva Fortunato, Renata Pereira Alves, Karinne Spirandelli Carvalho Naves, Monica Cassel","doi":"10.5115/acb.24.304","DOIUrl":"https://doi.org/10.5115/acb.24.304","url":null,"abstract":"Pneumonia is often triggered by a bacterial infection, in many cases Staphylococcus aureus. Although this bacterium is found in the microbiota of healthy individuals, it can proliferate and release toxins in the respiratory tract, causing tissue damage by activating the inflammatory process and cell death pathways and resulting in serious complications. In this study, pneumonia was induced in Balb/c mice using different concentrations of S. aureus to evaluate histopathological changes and progression with increasing concentrations of colony forming units (CFUs) as well as their interactions with inflammatory and cell death markers. Hematoxylin and eosin histological techniques and peroxidase immunohistochemistry were utilized to investigate outcomes that included edema and disruption of the bronchiole and blood vessel walls. Alveolar collapse and bronchiolar hyperplasia were also analyzed and were statistically significant, but only hyperplasia varied between the two groups that received intermediate concentrations of CFU (107 and 108, respectively) to induce pneumonia. In the immunohistochemical analysis, progression of apoptosis was observed in groups that received up to 108 CFU, along with a probable predominance of autophagy and reduction in IL-6 in the group that received the highest concentration (109 CFU). These characteristics appear to indicate an attempt to preserve and reuse cells when high CFU concentrations are present and eliminate infected cells at lower concentrations. The data from this present study contribute to understanding crosstalk between cell death pathways and the inflammatory response in S. aureus-induced pneumonia, and may assist in future intervention strategies.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphology and morphometry of pudendal nerve in East Indian population with surgical implications: a cadaveric study. 具有外科意义的东印度人群阴部神经形态学和形态计量学：一项尸体研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-06-02 DOI: 10.5115/acb.25.012

Grace Suganya, Biswabina Ray, Yashu Bharadwaj

{"title":"Morphology and morphometry of pudendal nerve in East Indian population with surgical implications: a cadaveric study.","authors":"Grace Suganya, Biswabina Ray, Yashu Bharadwaj","doi":"10.5115/acb.25.012","DOIUrl":"https://doi.org/10.5115/acb.25.012","url":null,"abstract":"Pudendal nerve entrapment clinically has a wide spectrum of presentation ranging from urinary to anorectal and sexual dysfunction. The caliber of the pudendal nerve should be matched with calibre of donor nerve for a successful nerve transfer. Hence, we aimed at evaluating the morphology, dimensions of pudendal nerve at various sites of entrapment and certain trajectory distances to approach the pudendal nerve surgically. The study was conducted at Department of Anatomy at a tertiary care hospital and medical college. A detailed dissection of pudendal nerve was done and the morphology and morphometry of the pudendal nerve were studied in 10 cadavers with equal sex distribution (5 male and 5 female). Crosssectional area (CSA) of the pudendal nerve at various sites of entrapment (piriformis, sacrospinous ligament, sacrotuberous ligament, and at Alcock's canal) and trajectory distance of pudendal nerve from various anatomical landmarks (ischial spine, sacral tuberosity, pubic symphysis, and inferior pubic ramus) were measured using digital vernier caliper. The CSA of pudendal nerve was more at piriformis (4.04 mm2) it decreased as the nerve travelled further to Alcock's canal (0.35 mm2). On comparison of the CSA and trajectory distances of the pudendal nerve with sex and sides there was no statistically significant difference. Morphologically, formation variation of pudendal nerve from S3 and S4 roots and trunk variations were also observed. These findings of the present study would help in various surgeries of perineum like nerve transfer, in placement of Richters stitch, transobturator tapes, pudendal nerve block etc.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The muscular branching characteristics of the deep peroneal nerve in adult human cadavers. 成人尸体腓深神经的肌肉分支特征。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-05-23 DOI: 10.5115/acb.25.017

Kıvanç Goral, Tania Marur

{"title":"The muscular branching characteristics of the deep peroneal nerve in adult human cadavers.","authors":"Kıvanç Goral, Tania Marur","doi":"10.5115/acb.25.017","DOIUrl":"https://doi.org/10.5115/acb.25.017","url":null,"abstract":"The aim of this study was to investigate the number of muscular branches and muscular branching characteristics of the deep peroneal nerve to the muscles. In this study, a total of 16 lower extremities from 8 male cadavers fixed with formalin, ethanol, and glycerol solution were dissected and the number of muscular branches of the deep peroneal nerve and muscular branching features were investigated. It was observed that 31.5% of the muscular branches given by the deep peroneal nerve came to the tibialis anterior muscle, 28.9% to the extensor digitorum longus muscle, 25.5% to the extensor hallucis longus muscle, 11.4% to the peroneus tertius muscle and 2.7% to the peroneus longus muscle. Muscular branches to the tibialis anterior muscle, extensor digitorum longus muscle, and peroneus tertius muscle were generally originated from the deep peroneal nerve in the proximal 1/3 of the leg. Muscular branches to the extensor hallucis longus muscle arose usually from the deep peroneal nerve in the middle 1/3 of the leg. We think that the data we obtained in our research will reduce the rate of important complications such as neurovascular injury in interventions planned for the deep peroneal nerve and the structures adjacent to the nerve.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A potential interference of chemoreception in inflamed vomeronasal organ with experimental autoimmune encephalomyelitis. 实验性自身免疫性脑脊髓炎炎症的犁鼻器官化疗接受的潜在干扰

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-05-23 DOI: 10.5115/acb.25.020

Kyungsook Jung, Deokho Ko, Sungmoo Hong, Irene Ortiz-Leal, Pablo Sanchez-Quinteiro, Meejung Ahn, Changjong Moon, Taeyoung Kang, Taekyun Shin, Jeongtae Kim

引用次数: 0

Anatomical variations of the infrahyoid muscles and ansa cervicalis: a systematic review and an updated classification system for the omohyoid muscle. 舌骨下肌和颈袢的解剖变异：对肩胛舌骨肌的系统回顾和更新的分类系统。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.307

Nymfodora Malkidou, Vasileios Papadopoulos, Aliki Fiska

{"title":"Anatomical variations of the infrahyoid muscles and ansa cervicalis: a systematic review and an updated classification system for the omohyoid muscle.","authors":"Nymfodora Malkidou, Vasileios Papadopoulos, Aliki Fiska","doi":"10.5115/acb.24.307","DOIUrl":"https://doi.org/10.5115/acb.24.307","url":null,"abstract":"The four infrahyoid muscles of the anterior neck are primarily innervated by the ansa cervicalis. This systematic review aims to evaluate the range of the anatomical variations in these muscles and their relationship to innervation patterns. A systematic search was conducted using PubMed and Google Scholar databases. Articles reporting variations in infrahyoid muscles and/or ansa cervicalis were independently evaluated following the PICOTS framework. The anatomical quality assessment tool was used to assess the quality of publications reporting anatomical variants. Seventy-seven studies, encompassing eighty-four cases, were included in the analysis. Of the 56-publication reporting infrahyoid muscle variations, 44 pertained to the omohyoid muscle (main or accessory), 3 to the sternohyoid, 4 to the sternothyroid, and 1 to the thyrohyoid, with no accessory variation observed in the latter. Atypical infrahyoid muscles were identified in 11 cases, 9 of which presented as levator glandulae thyroideae, and 2 as single cases. Variations in the ansa cervicalis were documented in 29 cases, only 1 case involved both ansa cervicalis and infrahyoid muscle variations. The extensive variability of the omohyoid muscle led to the development of a new classification system that integrates 4 types of consistency and 4 types of morphometric variations, providing valuable insights for clinical practice. The specialized use of the infrahyoid muscles in cancer staging, reconstruction after neck cancer surgery, and thyroid surgery underscores the need for a new framework to document their variations, particularly in the omohyoid muscle.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aberrant rib cage anatomy with false ribs attachment to the sternum: review of the literature focused on slipping ribs syndrome case reports. 异常胸腔解剖与假肋骨附着于胸骨：文献回顾侧重于肋骨滑移综合征病例报告。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.227

Sayed Mehrdad Azimi, Fateme Keshtparvar, Zahra Sadeghi, Hamid Bahramian

{"title":"Aberrant rib cage anatomy with false ribs attachment to the sternum: review of the literature focused on slipping ribs syndrome case reports.","authors":"Sayed Mehrdad Azimi, Fateme Keshtparvar, Zahra Sadeghi, Hamid Bahramian","doi":"10.5115/acb.24.227","DOIUrl":"https://doi.org/10.5115/acb.24.227","url":null,"abstract":"The thoracic cage, formed by ribs and sternum, protects vital organs while enabling respiration. This review examines anatomical variations in rib-sternum attachments and their clinical significance through analysis of literature from 1993-2023. Variations, including bifid ribs (0.15%-3.4% prevalence) and cervical ribs (0.05%-3.0%), can lead to conditions like slipping rib syndrome (SRS). An extensive search of PubMed, Embase, Google Scholar, Web of Science, and specialized collections identified 17 comprehensive SRS case reports. Two independent reviewers evaluated these cases, revealing that rib-sternum morphological variations significantly impact respiratory biomechanics, with unstable costal cartilage identified as a primary cause of pain syndromes. These findings highlight the critical importance of recognizing aberrant rib-sternum anatomy for patient safety, particularly in thoracic procedures. Advanced imaging technologies have enhanced detection capabilities, allowing for improved surgical planning and patient management. This review underscores the value of both cadaveric and radiological examination in identifying these variations, and recommends further research to clarify their prevalence, functional implications, and clinical correlations to optimize treatment approaches and outcomes.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenging arterial patterns of renal and testicular arteries in a human cadaver: clinical significance and embryological bases revisited. 具有挑战性的人尸体肾和睾丸动脉的动脉模式：临床意义和胚胎学基础重新审视。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-30 DOI: 10.5115/acb.24.336

Wenshao Cai, Minyan Shi, David W Chan, Baohua Luo, Abudureyimujiang Ruze

引用次数: 0

Histomorphogenesis of human pancreatic islets amidst maternal anaemia: a critical insight. 人胰岛在母体贫血中的组织形态发生：一个关键的见解。

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-23 DOI: 10.5115/acb.24.274

Sruthy Babu, Pravash Ranjan Mishra, Praveen Kumar Ravi, Sashikanta Swain, Jasmina Begum, Madhumita Patnaik

{"title":"Histomorphogenesis of human pancreatic islets amidst maternal anaemia: a critical insight.","authors":"Sruthy Babu, Pravash Ranjan Mishra, Praveen Kumar Ravi, Sashikanta Swain, Jasmina Begum, Madhumita Patnaik","doi":"10.5115/acb.24.274","DOIUrl":"https://doi.org/10.5115/acb.24.274","url":null,"abstract":"Maternal anaemia, the most common nutritional deficiency, adversely affects the growth and development of the fetus as a whole and the fetal pancreas in particular. These changes lead to the young onset of diabetes in the near future. To understand the pathophysiology behind this, present study investigates the histomorphogenesis of human fetal pancreatic islets and the impact of maternal anaemia on islet dimension, area proportion, and cellular composition across various gestational weeks using immunohistochemistry. The research was conducted on 18 human fetal pancreases obtained from spontaneous abortions or stillbirths between 17 to 36 weeks of gestation, categorized into normal (n=10) and anaemic (n=8) maternal groups. Results revealed a larger islet diameter in fetuses from anaemic mothers compared to the non-anaemic group (P=0.039). The beta cell percentage was significantly lower in the anaemic group across all gestational ages (P=0.003), while the alpha cell proportion remained unchanged in the anaemic group but increased significantly in the non-anaemic group after 20 weeks (P=0.006). The non-alpha/beta cell proportion in anaemic group was consistently higher than in the non-anaemic group. In conclusion, maternal anaemia results in the reprogramming of fetal pancreatic islets, characterized by a reduction in beta cell proportion, an increase in non-alpha/beta cells, and a disruption in the alpha-to-beta cell ratio. These changes may impair fetal pancreatic function and predispose the offspring to glucose intolerance and diabetes in later life. Ensuring adequate maternal nutrition through iron and folic acid supplementation during pregnancy is essential to prevent these developmental disruptions.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective effect of Chlorella vulgaris against experimental hepatic ischemia reperfusion injury downregulating oxidative stress, inflammation, and apoptosis. 下调氧化应激、炎症和细胞凋亡的小球藻对实验性肝缺血再灌注损伤的保护作用

IF 1.4

Anatomy & Cell Biology Pub Date : 2025-04-23 DOI: 10.5115/acb.24.318

Amira E Farage, Mona A Abdel-Kareem, Medhat Taha, Sara Abubakr, Nora Elshehawy Helal, Mahmoud Hendawy, Hanan A Elgendy, Ahmed Abdel-Monem Elmetwally, Hala Mahfouz, Tourki A S Baokbah, Mohammed R Rabei, Mohammad Akbar Hossain, Azza I Helal, Mohie Mahmoud Ibrahim

{"title":"Protective effect of Chlorella vulgaris against experimental hepatic ischemia reperfusion injury downregulating oxidative stress, inflammation, and apoptosis.","authors":"Amira E Farage, Mona A Abdel-Kareem, Medhat Taha, Sara Abubakr, Nora Elshehawy Helal, Mahmoud Hendawy, Hanan A Elgendy, Ahmed Abdel-Monem Elmetwally, Hala Mahfouz, Tourki A S Baokbah, Mohammed R Rabei, Mohammad Akbar Hossain, Azza I Helal, Mohie Mahmoud Ibrahim","doi":"10.5115/acb.24.318","DOIUrl":"https://doi.org/10.5115/acb.24.318","url":null,"abstract":"Hepatic ischemia/reperfusion (Hep I/R) is a great health burden during hepatic transplantation surgery. The present work aimed to examine the mitigative effect of Chlorella vulgaris against Hep I/R and its underlying protective mechanisms. The animals in the present research were classified into four equal experimental groups (n=6): the sham group, sham+Chlorella vulgaris group, Hep I/R group, and Hep I/R+Chlorella vulgaris group. Hepatic ischemia results in liver impairment, as evidenced by elevated liver enzyme levels and altered liver histology. It also reduced antioxidant enzyme levels and increased lipid peroxidation. Additionally, the Hep I/R group displayed significant suppression of the nuclear factor erythroid 2-related factor 2 (Nrf2)/haem oxygenase-1 pathway. There was a marked elevation in the expression of inflammatory markers, including nuclear factor kappa beta (NF-κB), tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6, and myloperoxidase, and NOD-like receptor protein 3 (NLRP3) and caspase-1. Furthermore, the levels of apoptotic markers such as caspase-3 and Bax were greater than those in the sham groups. Pretreatment with Chlorella vulgaris significantly protected against Hep I/R by reversing these effects. Rats pretreated with Chlorella vulgaris exhibited a hepatoprotective effect against Hep I/R through its inhibition of the NF-κB and NLRP3 cascades and Nrf2 stimulation.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0