Anatomy & Cell Biology最新文献_第10页

In search of subcortical and cortical morphologic alterations of a normal brain through aging: an investigation by computed tomography scan. 寻找正常大脑在衰老过程中皮层下和皮层形态的变化：计算机断层扫描研究。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-12-11 DOI: 10.5115/acb.23.219

Mehrdad Ghorbanlou, Fatemeh Moradi, Mohammad Hassan Kazemi-Galougahi, Maasoume Abdollahi

{"title":"In search of subcortical and cortical morphologic alterations of a normal brain through aging: an investigation by computed tomography scan.","authors":"Mehrdad Ghorbanlou, Fatemeh Moradi, Mohammad Hassan Kazemi-Galougahi, Maasoume Abdollahi","doi":"10.5115/acb.23.219","DOIUrl":"10.5115/acb.23.219","url":null,"abstract":"Morphologic changes in the brain through aging, as a physiologic process, may involve a wide range of variables including ventricular dilation, and sulcus widening. This study reports normal ranges of these changes as standard criteria. Normal brain computed tomography scans of 400 patients (200 males, 200 females) in every decade of life (20 groups each containing 20 participants) were investigated for subcortical/cortical atrophy (bicaudate width [BCW], third ventricle width [ThVW], maximum length of lateral ventricle at cella media [MLCM], bicaudate index [BCI], third ventricle index [ThVI], and cella media index 3 [CMI3], interhemispheric sulcus width [IHSW], right hemisphere sulci diameter [RHSD], and left hemisphere sulci diameter [LHSD]), ventricular symmetry. Distribution and correlation of all the variables were demonstrated with age and a multiple linear regression model was reported for age prediction. Among the various parameters of subcortical atrophy, BCW, ThVW, MLCM, and the corresponding indices of BCI, ThVI, and CMI3 demonstrated a significant correlation with age (R2≥0.62). All the cortical atrophy parameters including IHSW, RHSD, and LHSD demonstrated a significant correlation with age (R2≥0.63). This study is a thorough investigation of variables in a normal brain which can be affected by aging disclosing normal ranges of variables including major ventricular variables, derived ventricular indices, lateral ventricles asymmetry, cortical atrophy, in every decade of life introducing BW, ThVW, MLCM, BCI, ThVI, CMI3 as most significant ventricular parameters, and IHSW, RHSD, LHSD as significant cortical parameters associated with age.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"45-60"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138794580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atlanto-occipital assimilation: embryological basis and its clinical significance. 寰枕同化：胚胎学基础及其临床意义。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-12-20 DOI: 10.5115/acb.23.225

Hari Hara Hanusun N, Akanksha Singh, Pooja Poddar, Jessy J P, Neerja Rani, Hitesh Gurjar, Seema Singh

引用次数: 0

A biceps-bicaudatus sartorius muscle: dissection of a variant with possible clinical implications. 肱二头肌-冈底斯肌：解剖变体，可能具有临床意义。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-03 DOI: 10.5115/acb.23.254

Konstantinos Natsis, Christos Koutserimpas, Trifon Totlis, George Triantafyllou, George Tsakotos, Katerina Al Nasraoui, Filippos Karageorgos, Maria Piagkou

引用次数: 0

Impact of peripheral blood mononuclear cells preconditioned by activated platelet supernatant in managing gastric mucosal damage induced by zinc oxide nanoparticles in rats. 用活化血小板上清液预处理外周血单核细胞对控制氧化锌纳米颗粒诱发的大鼠胃黏膜损伤的影响

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-15 DOI: 10.5115/acb.23.217

Darwish Badran, Ayman El-Baz El-Agroudy, Amira Adly Kassab, Khaled Saad El-Bayoumi, Zienab Helmy Eldken, Noha Ramadan Mohammed Elswaidy

{"title":"Impact of peripheral blood mononuclear cells preconditioned by activated platelet supernatant in managing gastric mucosal damage induced by zinc oxide nanoparticles in rats.","authors":"Darwish Badran, Ayman El-Baz El-Agroudy, Amira Adly Kassab, Khaled Saad El-Bayoumi, Zienab Helmy Eldken, Noha Ramadan Mohammed Elswaidy","doi":"10.5115/acb.23.217","DOIUrl":"10.5115/acb.23.217","url":null,"abstract":"The world has witnessed tremendous advancements in nano-base applications. Zinc oxide nanoparticles (ZON) are widely used in food industry and medicine. Although their application is of important value, they may cause toxicity to body tissues. Peripheral blood mononuclear cells (PBMCs) proved its efficacy in tissue regeneration especially when it is preconditioned by activated platelet supernatant (APS). The aim of this study is to evaluate the effect of ZON on the gastric mucosa and the therapeutic role of the PBMCs preconditioned by APS in rats. Ten rats were donors and fifty rats were recipients. The recipients were divided into; control group, ZON group (10 mg/kg/day orally for five days) and preconditioned PBMCs group (1×107 once intravenously 24 hours after ZON). Gastric specimens were processed for histological, immunohistochemical, biochemical and quantitative real-time polymerase chain reaction studies. ZON group showed marked structural changes in the gastric mucosa. There was desquamation or deep ulceration of the epithelium. Cytoplasmic vacuoles and pyknotic nuclei were in glandular cells. Reduced proliferating cell nuclear antigen and increased tumor necrosis factor-α were in epithelial cells. There were significant elevation in malondialdahyde and reduction in glutathione, superoxide dismutase, and catalase. Enhancement in mRNA expression of nuclear factor kappa-B and cyclooxygenase-2 was detected. The preconditioned PBMCs group showed significant improvement of all parameters. So, ZON had cytotoxic effects on the gastric mucosa and the preconditioned PBMCs had a therapeutic effect on gastric mucosal damage after ZON.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"105-118"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139465771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive review of the mental spine. 全面回顾精神脊柱。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-12-15 DOI: 10.5115/acb.23.220

Ross Champagne, Rithvik Vutukuri, Chung Yoh Kim, R Shane Tubbs, Joe Iwanaga

引用次数: 0

Exploring amygdala structural changes and signaling pathways in postmortem brains: consequences of long-term methamphetamine addiction. 探索死后大脑的杏仁核结构变化和信号通路:长期甲基苯丙胺成瘾的后果。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2023-11-22 DOI: 10.5115/acb.23.193

Zahra Azimzadeh, Samareh Omidvari, Somayeh Niknazar, Saeed Vafaei-Nezhad, Navid Ahmady Roozbahany, Mohammad-Amin Abdollahifar, Foozhan Tahmasebinia, Gholam-Reza Mahmoudiasl, Hojjat Allah Abbaszadeh, Shahram Darabi

{"title":"Exploring amygdala structural changes and signaling pathways in postmortem brains: consequences of long-term methamphetamine addiction.","authors":"Zahra Azimzadeh, Samareh Omidvari, Somayeh Niknazar, Saeed Vafaei-Nezhad, Navid Ahmady Roozbahany, Mohammad-Amin Abdollahifar, Foozhan Tahmasebinia, Gholam-Reza Mahmoudiasl, Hojjat Allah Abbaszadeh, Shahram Darabi","doi":"10.5115/acb.23.193","DOIUrl":"10.5115/acb.23.193","url":null,"abstract":"Methamphetamine (METH) can potentially disrupt neurotransmitters activities in the central nervous system (CNS) and cause neurotoxicity through various pathways. These pathways include increased production of reactive nitrogen and oxygen species, hypothermia, and induction of mitochondrial apoptosis. In this study, we investigated the long-term effects of METH addiction on the structural changes in the amygdala of postmortem human brains and the involvement of the brain- cAMP response element-binding protein/brain-derived neurotrophic factor (CREB/BDNF) and Akt-1/GSK3 signaling pathways. We examined ten male postmortem brains, comparing control subjects with chronic METH users, using immunohistochemistry, real-time polymerase chain reaction (to measure levels of CREB, BDNF, Akt-1, GSK3, and tumor necrosis factor-α [TNF-α]), Tunnel assay, stereology, and assays for reactive oxygen species (ROS), glutathione disulfide (GSSG), and glutathione peroxidase (GPX). The findings revealed that METH significantly reduced the expression of BDNF, CREB, Akt-1, and GPX while increasing the levels of GSSG, ROS, RIPK3, GSK3, and TNF-α. Furthermore, METH-induced inflammation and neurodegeneration in the amygdala, with ROS production mediated by the CREB/BDNF and Akt-1/GSK3 signaling pathways.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"70-84"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138294482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The pterygomandibular raphe: a comprehensive review. 翼下颌剑突：全面回顾。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-30 DOI: 10.5115/acb.23.232

Rithvik Vutukuri, Norio Kitagawa, Keiko Fukino, R Shane Tubbs, Joe Iwanaga

引用次数: 0

A novel histologic description of the fibrous networks in the lid-cheek junction and infraorbital region. 睑颊交界处和眶下区纤维网的新组织学描述。

IF 1.1

Anatomy & Cell Biology Pub Date : 2024-03-31 Epub Date: 2024-01-26 DOI: 10.5115/acb.23.275

Sang-Hee Lee, Kyu-Ho Yi, Jung-Hee Bae, You-Jin Choi, Young-Chun Gil, Kyung-Seok Hu, Eqram Rahman, Hee-Jin Kim

{"title":"A novel histologic description of the fibrous networks in the lid-cheek junction and infraorbital region.","authors":"Sang-Hee Lee, Kyu-Ho Yi, Jung-Hee Bae, You-Jin Choi, Young-Chun Gil, Kyung-Seok Hu, Eqram Rahman, Hee-Jin Kim","doi":"10.5115/acb.23.275","DOIUrl":"10.5115/acb.23.275","url":null,"abstract":"The aim of this study was to identify the anatomical feature of retaining ligament and fat compartment on the lower eyelid and infraorbital region using a histological method, and to investigate clear definitions for them which could be used generally in the clinical area. Eighteen specimens from eight fresh Korean cadavers were stained with Masson trichrome or hematoxylin and eosin. The ligamentous and fascial fibrous tissue were clearly identified. The ligamentous fibrous tissue which traversed in the superficial and deep fat layer was skin ligament and orbicularis retaining ligament (ORL). The fascial fibrous tissue enclosed the orbicularis oculi muscle (OOc) and circumferencial adipose tissue. Based on the ligamentous and fascial structure, three fat compartments, septal, suborbicularis oculi and infraorbital fat compartment, could be identified. The OOc attached to orbital rim and dermis by ORL and skin ligament, and the muscle fascicle and fat fascicle provided the connection point to the ORL and skin ligament as enclosing all muscle and fat tissue. The combination of the force made by the skin ligament in the lower eyelid and ORL may decide the level and form of the infraorbital grooves.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"25-30"},"PeriodicalIF":1.1,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10968187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fenestrated popliteal vein pierced by a branch of the tibial nerve. 被胫神经分支刺穿的腘静脉裂孔。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-08-08 DOI: 10.5115/acb.23.035

Edward C Muo, Joe Iwanaga, Juan J Cardona, Łukasz Olewnik, Aaron S Dumont, R Shane Tubbs

引用次数: 0

Analyzing the factors that contribute to the development of embryological classical type of bladder exstrophy. 分析导致膀胱萎缩胚胎学经典类型发展的因素。

IF 1.1

Anatomy & Cell Biology Pub Date : 2023-12-31 Epub Date: 2023-08-31 DOI: 10.5115/acb.23.056

Ria Margiana, Widya Juwita, Khoirul Ima, Zakiyatul Faizah, Supardi Supardi

{"title":"Analyzing the factors that contribute to the development of embryological classical type of bladder exstrophy.","authors":"Ria Margiana, Widya Juwita, Khoirul Ima, Zakiyatul Faizah, Supardi Supardi","doi":"10.5115/acb.23.056","DOIUrl":"10.5115/acb.23.056","url":null,"abstract":"Bladder exstrophy is a rare congenital condition of the pelvis, bladder, and lower abdomen that opens the bladder against the abdominal wall, produces aberrant growth, short penis, upward curvature during erection, wide penis, and undescended testes. Exstrophy affects 1/30,000 newborns. The bladder opens against the abdominal wall in bladder exstrophy, a rare genitourinary condition. This study is vital to provide appropriate therapy choices as a basis to improve patient outcomes. This study may explain bladder exstrophy and provide treatment. Epispadias, secretory placenta, cloacal exstrophy, and other embryonic abnormalities comprise the exstrophy-spades complex. The mesenchymal layer does not migrate from the ectoderm and endoderm layers in the first trimester, affecting the cloacal membrane. Embryological problems define the exstrophy-aspidistra complex, which resembles epimedium, classic bladder, cloacal exstrophy, and other diseases. Urogenital ventral body wall anomalies expose the bladder mucosa, causing bladder exstrophy. Genetic mutations in the Hedgehog cascade pathway, Wnt signal, FGF, BMP4, Alx4, Gli3, and ISL1 cause ventral body wall closure and urinary bladder failure. External factors such as high maternal age, smoking moms, and high maternal body mass index have also been associated to bladder exstrophy. Valproic acid increases bladder exstrophy risk; chemicals and pollutants during pregnancy may increase bladder exstrophy risk. Bladder exstrophy has no identified cause despite these risk factors. Exstrophy reconstruction seals the bladder, improves bowel function, reconstructs the vaginal region, and restores urination.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"421-427"},"PeriodicalIF":1.1,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10714095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10495139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0