Anatomy & Cell Biology最新文献_第9页

Factors associated with osteophytosis on the sella turcica: related morphological and morphometrical aspects. 蝶鞍骨赘病的相关因素：相关形态学和形态计量学方面。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-06-24 DOI: 10.5115/acb.25.080

David Ezra, R Shane Tubbs, Joe Iwanaga, Deborah Alperovitch-Najenson, Arthur Yosef, Israel Hershkovitz, James Cray

{"title":"Factors associated with osteophytosis on the sella turcica: related morphological and morphometrical aspects.","authors":"David Ezra, R Shane Tubbs, Joe Iwanaga, Deborah Alperovitch-Najenson, Arthur Yosef, Israel Hershkovitz, James Cray","doi":"10.5115/acb.25.080","DOIUrl":"10.5115/acb.25.080","url":null,"abstract":"The sella turcica, part of the sphenoid bone located at the base of the skull, is associated with multiple important neurovascular structures. Hence, a detailed knowledge of its variations is critical to clinicians who interpret imaging or surgeons who operate in this region. Our aim was to better understand the pathology of osteophytosis, often found related to the sella turcica. The study sample (n=1,083, human skulls) was obtained from the skeleton collection housed in the Natural History Museum, Cleveland, OH, USA. All skulls were assessed for osteophytes in the sella turcica region (defined as an overgrowth of 1 mm or more). Morphometrical measurements included skull length, width, and thickness, correlated to seller osteophytes. Cranial shape was related to the presence of osteophytes. Greater prevalence was seen in the brachycephalic skulls, with a significantly higher ratio of presence in older people (79.6%) compared to a younger population (26.4%); greater prevalence was also observed in female skulls with a composite thickness of the frontal, parietal and occipital bones. A multifactorial analysis using a logistic regression model defined a statistically significant model, by explaining 37.0% of the variance in osteophyte presence and correctly classifying 77.2% of the cases. Female skulls were 1.76 times more likely to display osteophytes of the sella turcica. Increasing age and increased skull thickness were associated with an enhanced likelihood of exhibiting osteophytes involving the sella turcica, thereby, the shape of the skull, age, and sex partially explain the variations observed for the presence of sella turcica osteophytes.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"581-588"},"PeriodicalIF":1.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The problem with "borrowed" anatomy faculty: why medical anatomy isn't enough for dental education. “借用”解剖学师资的问题：为什么医学解剖学不足以满足牙科教育。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-11-07 DOI: 10.5115/acb.25.166

Joe Iwanaga, Norio Kitagawa, R Shane Tubbs

引用次数: 0

Revisiting the iliocapsularis: anatomy, variants, and its role in hip pathologies. 回顾髂囊：解剖、变异及其在髋关节病理中的作用。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-10-29 DOI: 10.5115/acb.25.094

Milee Patel, Erin L Brown, Jeremy K Lalla, Massimo S D'Antoni, Lauren M Dumont, Rarinthorn Samrid, Joe Iwanaga, R Shane Tubbs

{"title":"Revisiting the iliocapsularis: anatomy, variants, and its role in hip pathologies.","authors":"Milee Patel, Erin L Brown, Jeremy K Lalla, Massimo S D'Antoni, Lauren M Dumont, Rarinthorn Samrid, Joe Iwanaga, R Shane Tubbs","doi":"10.5115/acb.25.094","DOIUrl":"10.5115/acb.25.094","url":null,"abstract":"The iliocapsularis muscle (ICM), a small and often overlooked muscle of the anterior hip, has recently gained attention for its potential clinical and surgical relevance. Despite being anatomically distinct and commonly present, the ICM remains underappreciated among clinicians and anatomists. This narrative review aims to synthesize recent anatomical and clinical literature on the ICM, focusing on its origin, insertion, innervation, vascular supply, anatomical variations, histological features, and functional significance. The ICM originates from the anteromedial hip capsule and the anterior inferior iliac spine, typically inserting distal to the lesser trochanter. Its proposed function includes tightening the anterior hip capsule and stabilizing the femoral head. Electromyographic studies suggest that the ICM plays an active role during hip flexion and dynamic gait phases. Anatomical variations, including variant origins and insertions, have been documented, along with unique innervation and fascial compartmentalization. Clinically, the ICM serves as a useful landmark in total hip arthroplasty and periacetabular osteotomies. Its hypertrophy or atrophy has been linked to hip pathologies such as acetabular dysplasia and femoroacetabular impingement. Imaging modalities, including ultrasound and elastography, have further supported its diagnostic utility. This review emphasizes the need for greater recognition of the ICM's structure and function, underscoring its relevance in orthopedic procedures and hip pathology diagnostics.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"496-500"},"PeriodicalIF":1.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145385999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-headed duplicated omohyoid muscle in a human cadaver. 人类尸体上的三头复制肩胛舌骨肌。

IF 1.1

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-07-03 DOI: 10.5115/acb.25.118

Judney Cley Cavalcante, Bento João da Graça Azevedo Abreu, Wigínio Gabriel de Lira-Bandeira, Mauro Bezerra Montello, Nicol Zielinska, Łukasz Olewnik

引用次数: 0

Thermal touch and anatomical insight: Roman terracotta vessels as proto-clinical maps of the human body. 热接触和解剖洞察力：罗马兵马俑血管作为人体的原始临床地图。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-12-02 DOI: 10.5115/acb.25.205

Kun Hwang

{"title":"Thermal touch and anatomical insight: Roman terracotta vessels as proto-clinical maps of the human body.","authors":"Kun Hwang","doi":"10.5115/acb.25.205","DOIUrl":"10.5115/acb.25.205","url":null,"abstract":"In the Archaeological Museum of Nicosia, Cyprus, a collection of Roman terracotta vessels-dated to the 1st century BCE to 1st century CE-offers a compelling view into the convergence of empirical healing and early anatomical reasoning. These vessels, likely used for localized heat therapy, are distinctly shaped to contour specific body parts: ears, hands, feet, knees, abdomen, and thorax. With spouts for pouring warm liquids and cavities for radiating retained heat, they appear to have functioned as reusable \"hot bags\" for therapeutic application. Their deliberate anatomical shapes hint at a proto-clinical understanding of the body region, anticipating modern anatomical concepts such as aesthetic units, vascular territories, and lymphatic drainage zones. These vessels fall into distinct morphologies: craniofacial and auricular vessels, shaped for the side of the head or ear-reminiscent of the posterior auricular and superficial temporal angiosomes, and suggestive of treating headaches, neuralgia, or infections. Thoracoabdominal vessels, whose curved contours match rib cage and abdominal surfaces-suggesting therapeutic warmth for visceral discomfort or muscular tension. Upper and lower limb units, including knees, thighs, and elbows-likely used in joint pain or injuries. Distal extremity molds, notably for the hands and feet-organs that modern clinicians recognize as prone to cold exposure, vasospasm, and microvascular pathology. This paper repositions these clay forms not only as implements of care, but as anatomical \"drawings in relief\"-early, handmade representations of functional human zones. In doing so, they reconnect anatomy with the sensory and therapeutic traditions that first shaped it.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"652-655"},"PeriodicalIF":1.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145653024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rhubarb water extract as a promising gastroprotective agent in Tamoxifen induced parietal cell damage in female rats: a histological study. 大黄水提取物对他莫昔芬诱导的雌性大鼠壁细胞损伤的组织学研究。

IF 1.1

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-10-17 DOI: 10.5115/acb.25.087

Rahma Kamal-Al-Din Abou El-Nour, Rana Maged Yakout, Ehab Refaat Ibrahim, Mostafa Hassan Baky, Samaa Samir Kamar

{"title":"Rhubarb water extract as a promising gastroprotective agent in Tamoxifen induced parietal cell damage in female rats: a histological study.","authors":"Rahma Kamal-Al-Din Abou El-Nour, Rana Maged Yakout, Ehab Refaat Ibrahim, Mostafa Hassan Baky, Samaa Samir Kamar","doi":"10.5115/acb.25.087","DOIUrl":"10.5115/acb.25.087","url":null,"abstract":"Tamoxifen (TAM) is one of the most used drugs in the prevention and treatment of breast cancer. A set of common side effects was recorded associating its prolonged clinical use that ranges 3-10 years. This study aimed to investigate TAM-induced parietal cells (PCs) injury in rats and the possible protective effect of rhubarb (Rh) water extract (WE). Twenty-four adult female rats were distributed as: control group, TAM-group (3 mg/kg/day TAM for 4-weeks) and TAM+Rh-group (combined 3 mg/kg/day TAM and 20 mg/kg Rh-WE for 4-weeks). Blood sample before euthanizing rats was tested for vitamin-B12. PCs in stomach fundus were examined using histological and transmission electron microscopic studies, besides immunohistochemistry for Caspase-3, proliferating cell nuclear antigen (PCNA) and hydrogen potassium (H+/K+)-ATPase. Gastric homogenates were inspected for malondialdehyde (MDA) by ELISA. TAM intake induced structural and ultrastructural alteration in rat PCs including ballooning degeneration, apoptosis, decreased canaliculi, increased tubulovesicular system and irregular-shaped mitochondria. A significant increase of Caspase-3 immunostaining and MDA expression in gastric tissue was associated with a significant decrease of PCNA and H+/K+-ATPase-immunostaining and in serum vitamin-B12 as compared to the control group. Combined oral intake of TAM and Rh-WE revealed a significant reversal of the previous findings. Conclusion: Prolonged use of oral TAM substantially affected the structure and function of gastric PCs which can be ameliorated by Rh-WE.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"589-601"},"PeriodicalIF":1.1,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does ChatGPT know basic human anatomy? ChatGPT了解基本的人体解剖学吗？

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-10-29 DOI: 10.5115/acb.25.181

Mike Yoshio Hamasaki, Alessandra Oliveira Maia, Adroaldo Lunardelli

引用次数: 0

Cadaveric revelation of medial cutaneous nerve of the arm traversing the axillary vein. 横过腋窝静脉的手臂内侧皮神经尸露。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-07-23 DOI: 10.5115/acb.25.142

Punnapa Raviteja, Mrudula Chandrupatla, Rohini Motwani

引用次数: 0

Elevated osteopontin reflects systemic inflammation in experimental autoimmune encephalomyelitis. 实验性自身免疫性脑脊髓炎患者骨桥蛋白升高反映全身性炎症。

IF 1.1

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-08-27 DOI: 10.5115/acb.25.132

Sungmoo Hong, Kyungsook Jung, Taeyoung Kang, Meejung Ahn, Changjong Moon, Jeongtae Kim, Taekyun Shin

引用次数: 0

Silencing serine/arginine-rich splicing factor 1 to induce apoptosis and autophagy-dependent cell death in cholangiocarcinoma through the correction of oncogenic splicing errors. 沉默富含丝氨酸/精氨酸剪接因子1，通过纠正致癌剪接错误诱导胆管癌细胞凋亡和自噬依赖性细胞死亡。

IF 1.2

Anatomy & Cell Biology Pub Date : 2025-12-31 Epub Date: 2025-07-31 DOI: 10.5115/acb.25.052

Chaturong Inpad, Phichamon Phetchahwang, Phattarin Pothipan, Pawee Tangwiriyarotkul, Nuttanan Hongsrichan, Sukanya Horpaopan, Worasak Kaewkong

{"title":"Silencing serine/arginine-rich splicing factor 1 to induce apoptosis and autophagy-dependent cell death in cholangiocarcinoma through the correction of oncogenic splicing errors.","authors":"Chaturong Inpad, Phichamon Phetchahwang, Phattarin Pothipan, Pawee Tangwiriyarotkul, Nuttanan Hongsrichan, Sukanya Horpaopan, Worasak Kaewkong","doi":"10.5115/acb.25.052","DOIUrl":"10.5115/acb.25.052","url":null,"abstract":"Cholangiocarcinoma (CCA) is a bile duct cancer often linked to liver fluke infections. In Thailand, it has a high incidence and mortality rate due to imprecise symptoms, late diagnosis, and limited treatments. Our previous research identified gene-splicing errors as a factor in CCA progression. This study focused on the role of serine/arginine-rich splicing factors (SRSFs) in CCA. SRSF1-SRSF12 expressions were analyzed using reverse transcription polymerase chain reaction (RT-PCR), confirming upregulation with RT quantitative PCR, western blotting, and dataset analysis. One SRSF was selected for silencing in CCA cell lines (KKU-055 and KKU-213A) using small interfering RNAs. Cell proliferation and survival were assessed through various assays, while apoptosis and autophagy markers were analyzed using western blotting, immunofluorescence, RT-PCR, and transmission electron microscopy (TEM). Splicing errors in death-related genes were also examined. The results showed that SRSF1 was significantly overexpressed in CCA, especially among gastrointestinal cancers. Silencing SRSF1, particularly in KKU-213A cells, reduced cell proliferation and increased cell death. Apoptosis was marked by increased caspase-3 and BAX, decreased Bcl-2, and cytochrome C release. Autophagy was indicated by a higher LC3B-II/LC3B-I ratio, lower p62, and increased Beclin-1 and ATG5. TEM further confirmed apoptotic and autophagic cell changes. Splicing errors in key death-related genes, including Δ133p53, AGR2vH, MKNK2-b, PKM2, MCL-1L, and BIN1+12a, were also detected. These findings suggest that SRSF1 plays a key role in CCA by regulating apoptosis and autophagy. Its silencing promotes cancer cell death, partly by correcting oncogenic splicing errors, making it a potential target for CCA treatment.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"602-614"},"PeriodicalIF":1.2,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12719124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0