Anatomy & Cell Biology最新文献_第7页

Tetrapleura tetraptera fruit phenolics fraction protects against the impact of ischemic stroke-induced hippocampal distortions and memory deficits in Wistar rats. 四叶草果实酚类成分可防止缺血性中风引起的 Wistar 大鼠海马变形和记忆缺陷。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-10-04 DOI: 10.5115/acb.24.013

Onyinoyi Bethel Onimisi, Sunday Abraham Musa, Uduak Emmanuel Umana, Sonhap James Sambo, Wusa Makena

{"title":"Tetrapleura tetraptera fruit phenolics fraction protects against the impact of ischemic stroke-induced hippocampal distortions and memory deficits in Wistar rats.","authors":"Onyinoyi Bethel Onimisi, Sunday Abraham Musa, Uduak Emmanuel Umana, Sonhap James Sambo, Wusa Makena","doi":"10.5115/acb.24.013","DOIUrl":"10.5115/acb.24.013","url":null,"abstract":"Stroke is the most significant cause of disability worldwide. Despite mounting data supporting memory deficit after stroke, dysfunction and treatment effect mechanisms remain unknown. Phenolics can be found in a variety of fruits and vegetables. There is, however, a scarcity of research on the therapeutic potential of the phenolics fraction of Tetrapleura tetraptera (PTT) fruit against ischemic stroke-induced abnormalities in hippocampal tissue. The rats were divided into five groups: Group I, vehicle; group II, ischemia/reperfusion (I/R)+vehicle; group III, I/R+50 mg/kg minocycline (MNC); group IV, I/R+100 mg/kg PTT; and group V, I/R+200 mg/kg PTT. Ischemia was induced via bilateral common carotid artery occlusion for 30 minutes followed by reperfusion. PTT and MNC were intraorally administered daily for 7 days. Neurodegenerative changes, cornu ammonis 1 (CA1) and cornu ammonis 3 (CA3) pyramidal cell count, levels of oxidative stress indicators, and memory functions were assessed. Rats treated with PTT, as well as MNC compared to untreated I/R rats, showed a substantial (P<0.05) rise in catalase, superoxide dismutase, glutathione levels, as well as decreased lipid peroxidation and improved memory. I/R resulted in histoarchitectural distortions, a marked decrease (P<0.05) in the intensity of the Nissl substance, and a striking decrease (P<0.05) in the number of pyramidal cells in the CA1 and CA3. PTT and MNC-treated groups showed significant attenuation in all the above parameters. Taking together, these findings revealed that PTT attenuated oxidative stress, histologic alterations and substantially restored memory impairment in the I/R rat model.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"543-558"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142370784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unilateral partial duplication of a fetal variant posterior cerebral artery associated with anomalous origin of duplicated superior cerebellar artery: a case report. 胎儿变异大脑后动脉单侧部分重复伴小脑上动脉重复异常起源：病例报告。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-05-31 DOI: 10.5115/acb.24.026

Ehab Mostafa Elzawawy, Mumen Hamdi Al-Mutori, Hadil Salim Al Awaisi, Abdulrahman Abdulrahman Al Dagher, Mustafa Mohamed Allayeth, Hassan Reda Hassan Elsayed

{"title":"A unilateral partial duplication of a fetal variant posterior cerebral artery associated with anomalous origin of duplicated superior cerebellar artery: a case report.","authors":"Ehab Mostafa Elzawawy, Mumen Hamdi Al-Mutori, Hadil Salim Al Awaisi, Abdulrahman Abdulrahman Al Dagher, Mustafa Mohamed Allayeth, Hassan Reda Hassan Elsayed","doi":"10.5115/acb.24.026","DOIUrl":"10.5115/acb.24.026","url":null,"abstract":"Variations at the junction of embryonic internal carotid and vertebrobasilar systems are rare and associated with a high incidence of stroke. During cadaver dissection, we demonstrated for the first time a case of hypoplastic right vertebral artery associated with partial duplication of the distal part of the right P1 segment of a partial fetal posterior cerebral artery (FPCA) and bilateral duplication of superior cerebellar arteries (SCAs), of which, the upper right SCA originated from PCA. We hypothesize that the poor development of the right half of the vertebrobasilar system caused the persistence of FPCA with anomalous origin of the right upper SCA as well as partial duplication of P1 segment of PCA as a remnant of the weak anastomosis between the embryonic right PCA and the basilar system. Such complex variations provide a huge challenge in their diagnosis and in choosing the suitable treatment modality for the stroke.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"608-611"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141178937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonographic study and anatomical guidelines for botulinum neurotoxin injection into the parotid gland. 腮腺注射肉毒杆菌神经毒素的超声研究和解剖学指南。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-10-10 DOI: 10.5115/acb.23.255

Kyu-Ho Yi, Soo-Bin Kim, Hyewon Hu, Hee-Jin Kim

{"title":"Ultrasonographic study and anatomical guidelines for botulinum neurotoxin injection into the parotid gland.","authors":"Kyu-Ho Yi, Soo-Bin Kim, Hyewon Hu, Hee-Jin Kim","doi":"10.5115/acb.23.255","DOIUrl":"10.5115/acb.23.255","url":null,"abstract":"Benign enlargement of the parotid gland hypertrophy results in a bulky lateral facial contour and esthetic appearance. This study aimed to determine the depth from the skin surface to the parotid fascia, which encompasses the parotid gland. The anatomical properties of the parotid glands were evaluated in 40 patients using ultrasonography. An up-to-date understanding of the localization of botulinum neurotoxin (BoNT) injection based on anatomy could lead to better localization of the injection into the parotid gland through morphological measurements using data previously published from cadaveric studies. Measurement using the otobasion inferius as a landmark revealed parotideomasseteric fascia thickness averaging 4-6 mm from the skin surface, with the parotid gland extending approximately 15 mm anteriorly. Analysis showed a 3-7 mm thickness range, indicating an optimal injection depth for safety and efficacy in BoNT procedures. Utilizing the otobasion inferius as an anatomical landmark offers a practical approach for measuring parotideomasseteric fascia thickness, addressing cadaveric study limitations. These guidelines aim to maximize the effects of BoNT therapy, which can be useful in clinical settings, by minimizing its deleterious effects.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"498-502"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical and morphometric features of the profunda brachii artery. 肱深动脉的解剖和形态特征。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-10-24 DOI: 10.5115/acb.23.243

Yüsra Nur Şanlıtürk, Nurşen Zeybek, Özcan Gayretli, Adnan Öztürk

引用次数: 0

Study of confluence of hepatic veins application in liver transplantation. 肝静脉汇流在肝移植中的应用研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-06 DOI: 10.5115/acb.24.071

Alka Vithalrao Bhingardeo, Mrudula Chandrupatla, Suneeth Jogi, Annapurna Srirambhatla, Kumar Satish Ravi

{"title":"Study of confluence of hepatic veins application in liver transplantation.","authors":"Alka Vithalrao Bhingardeo, Mrudula Chandrupatla, Suneeth Jogi, Annapurna Srirambhatla, Kumar Satish Ravi","doi":"10.5115/acb.24.071","DOIUrl":"10.5115/acb.24.071","url":null,"abstract":"Liver has exceptional regeneration capacity which makes live donor liver transplantation a good surgical option for patients waiting for donors. Hepatic veins play major role in transplantation surgeries. Variations of hepatic veins can have great impact on surgical approach and outcome of the surgery. In the present study, total number of hepatic veins, presence and absence of accessory veins and confluence with its varied patterns were studied. We found maximum cases with 2 and 3 major hepatic veins which indicate presence of confluence. Confluence between left and middle hepatic veins was highest with 38% of total 54% of cases with confluence. We also found confluence between middle and accessory hepatic vein which is not mentioned in any present classifications. In addition, we have measured confluence length and diameter which holds significance in hepatic resection and anastomosis. The mean confluence length was 0.88±0.39 cm while mean confluence diameter was 0.57±0.20 cm. We found accessory hepatic veins in 15% of cases. The knowledge of this surgical anatomy and associated variations is of paramount importance in liver transplantation, radiological interventional procedures of liver and hepatic tumor resection procedures.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"517-522"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663525/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141892662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visualization of the infratemporal fossa: enhancing anatomical learning through three-dimensional modeling. 颞下窝的可视化：通过三维建模加强解剖学学习。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-19 DOI: 10.5115/acb.24.127

Woohyun Cho, Hye Jin Kim, Mi-Sun Hur, Han-Soo Lee, Kwan Hyun Youn

{"title":"Visualization of the infratemporal fossa: enhancing anatomical learning through three-dimensional modeling.","authors":"Woohyun Cho, Hye Jin Kim, Mi-Sun Hur, Han-Soo Lee, Kwan Hyun Youn","doi":"10.5115/acb.24.127","DOIUrl":"10.5115/acb.24.127","url":null,"abstract":"The infratemporal fossa and pterygopalatine fossa are critical pathways for blood vessels and nerves leading to the orbit, nasal cavity, and oral cavity. Anatomical observation of these areas is challenging for learners due to their complex connections with surrounding structures and their deep location within the body. Since it is not easy to understand this area in three dimensions with only textbook images, there is a need to produce three-dimensional (3D) content. Most existing 3D data have reconstructed the digital imaging and communication in medicine files from computed tomography images with high accuracy; however, the surrounding structures often obstruct the view. For this reason, this project utilized Cinema4D (R18) software to refine the modeled bones and to create 3D models of muscles, blood vessels, and nerves that accurately represent their anatomical shapes and pathways. To facilitate easier access for learners via PC, the content was converted into PDF format. This enables the educational materials to be more easily viewed and the main structures more clearly observed using a computer-based viewer.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"592-597"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical study of variations in the configurations of the circle of Willis in relation to age, sex, and diameters of the components. 对威利斯圈的构造变化与年龄、性别和各部分直径的关系进行解剖学研究。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-30 DOI: 10.5115/acb.24.020

Yasser Alharbi, Radi Ali M Al Saffar

{"title":"Anatomical study of variations in the configurations of the circle of Willis in relation to age, sex, and diameters of the components.","authors":"Yasser Alharbi, Radi Ali M Al Saffar","doi":"10.5115/acb.24.020","DOIUrl":"10.5115/acb.24.020","url":null,"abstract":"The circle of Willis (COW) refers to the anastomotic arterial network found on the brain base, tasked with provision of collateral circulation aimed at prevention of ischemia. The COW is of immense clinical importance especially with regard to the assessment of neurovascular diseases. Individuals portray significant variations in the COW's anatomical configuration. The present study seeks to evaluate the existing anatomical variations of the COW and within the anterior and posterior segments of the COW. Thus, the study seeks to evaluate the different anatomical variations of the COW and its segments and components within the study population. To attain the set objectives, the present study has utilized the angiographic images for studying the COW variants in patients who underwent cerebral angiography during assessment of different types of cerebral anomalies and conditions. Therefore, this study used conventional angiography as an important tool in the evaluation of the different variations in the COW, and is most appropriate for evaluation of smaller anatomical variations owing to its perfect spatial resolution and portrayal of COW anatomy. The study findings indicated the existence between age and sex, and anatomical variations of the COW, particularly with regard to diameters of COW components like basilar artery (BA), P1, and internal carotid arterys (ICAs). Males had bigger BA, P1 and ICA diameters than females, while individuals aged below 40 years had bigger BA, A1, posterior communicating artery, and ICA diameters than those aged above 40 years.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"579-591"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare variation in popliteal artery branching: anterior tibial artery and fibular artery from the common tibiofibular trunk. 腘动脉分支的罕见变异：来自胫腓总干的胫前动脉和腓动脉。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-07-18 DOI: 10.5115/acb.24.086

Caitlin Sachsenmeier, Debilea Chapel, Randy Kulesza

引用次数: 0

An unreported variant of palmaris longus muscle. 一种未经报道的掌长肌变异。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-19 DOI: 10.5115/acb.24.060

Satheesha Badagabettu Nayak, Vasanthakumar Packiriswamy, Soumya Kodimajalu Vasudeva

引用次数: 0

Platelet-rich plasma protects hippocampal neurons and memory functions in a rat model of vascular dementia. 富血小板血浆可保护血管性痴呆大鼠模型中的海马神经元和记忆功能。

IF 1.4

Anatomy & Cell Biology Pub Date : 2024-12-31 Epub Date: 2024-08-21 DOI: 10.5115/acb.24.117

Ji-Hyun Moon, Ah La Choi, Hyeon-Jeong Noh, Jae Hwang Song, Geum-Lan Hong, Nam Seob Lee, Young-Gil Jeong, Seung Yun Han

{"title":"Platelet-rich plasma protects hippocampal neurons and memory functions in a rat model of vascular dementia.","authors":"Ji-Hyun Moon, Ah La Choi, Hyeon-Jeong Noh, Jae Hwang Song, Geum-Lan Hong, Nam Seob Lee, Young-Gil Jeong, Seung Yun Han","doi":"10.5115/acb.24.117","DOIUrl":"10.5115/acb.24.117","url":null,"abstract":"Platelet-rich plasma (PRP) is a promising biomaterial rich in bioactive growth factors, offering potential as a therapeutic agent for various diseases. However, its effectiveness in central nervous system disorders like vascular dementia (VaD) remains underexplored. This study investigated the potential of PRP to mitigate VaD progression in vivo. A rat model of VaD was established via bilateral common carotid artery occlusion and hypovolemia operation. Rats were randomly assigned to receive either PRP or platelet-poor plasma (PPP)-the latter being a byproduct of PRP preparation and used as a reference standard-resulting in the groups designated as 'operated group (OP)+PRP' and 'OP+PPP', respectively. PRP or PPP (500 μl) was administered intraperitoneally on the day of the operation and postoperative days 2, 4, 6, and 8. Cognitive function was assessed using the Y-maze, Barnes maze, and passive avoidance tests. On postoperative day 8, hippocampal samples were subjected to histological and semi-quantitative analyses. OP exhibited significant memory decline compared to controls, while the 'OP+PRP' group showed notable improvement. Histological analysis revealed increased neuronal loss and neuroinflammation in OP hippocampi, mitigated in 'OP+PRP'. Semi-quantitative analysis showed decreased expression of brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin receptor kinase B (TrkB) in OP, restored in 'OP+PPP' and further in 'OP+PRP'. These results highlight PRP's protective effects against VaD-induced hippocampal damage and cognitive impairment, partially attributed to BDNF/TrkB pathway upregulation.","PeriodicalId":7831,"journal":{"name":"Anatomy & Cell Biology","volume":" ","pages":"559-569"},"PeriodicalIF":1.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0