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Ca2+ homeostasis and male fertility: a target for a new male contraceptive system Ca2+ 稳态与男性生育能力：新型男性避孕系统的目标
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-04-28 DOI: 10.1080/19768354.2024.2345647
Kyung-Ha Lee, Jae Yeon Hwang
{"title":"Ca2+ homeostasis and male fertility: a target for a new male contraceptive system","authors":"Kyung-Ha Lee, Jae Yeon Hwang","doi":"10.1080/19768354.2024.2345647","DOIUrl":"https://doi.org/10.1080/19768354.2024.2345647","url":null,"abstract":"Ca2+ is a key secondary messenger that determines sperm motility patterns. Mammalian sperm undergo capacitation, a process to acquire fertilizing ability, in the female reproductive tract. Capacita...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"36 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140810074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sonic vibration ameliorates inflammatory diseases via the up-regulation of IL-10 声波振动通过上调 IL-10 改善炎症性疾病
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-04-26 DOI: 10.1080/19768354.2024.2346598
Huijeong Ahn, Eui-Man Jung, Min-Woo Cho, Meoung-Geun Shin, Jae-Yeong Choi, Geun-Shik Lee
{"title":"Sonic vibration ameliorates inflammatory diseases via the up-regulation of IL-10","authors":"Huijeong Ahn, Eui-Man Jung, Min-Woo Cho, Meoung-Geun Shin, Jae-Yeong Choi, Geun-Shik Lee","doi":"10.1080/19768354.2024.2346598","DOIUrl":"https://doi.org/10.1080/19768354.2024.2346598","url":null,"abstract":"Sonic vibration (SV), or vibroacoustic therapy, is applied to enhance local and systemic blood circulation and alleviate pain using low-frequency sine wave vibrations. However, there is limited sci...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"26 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140842353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ginkgo biloba extract ameliorates skin fibrosis in a bleomycin-induced mouse model of systemic sclerosis 银杏叶提取物可改善博莱霉素诱导的系统性硬化症小鼠模型的皮肤纤维化状况
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-04-18 DOI: 10.1080/19768354.2024.2337761
Beomgu Lee, Jong Seong Roh, Hoim Jeong, Yerin Kim, Jihyeon Lee, Changun Yun, Jiyoung Park, Da-sol Kim, Jungsoo Lee, Min Wook So, Aran Kim, Dong Hyun Sohn, Seung-Geun Lee
{"title":"Ginkgo biloba extract ameliorates skin fibrosis in a bleomycin-induced mouse model of systemic sclerosis","authors":"Beomgu Lee, Jong Seong Roh, Hoim Jeong, Yerin Kim, Jihyeon Lee, Changun Yun, Jiyoung Park, Da-sol Kim, Jungsoo Lee, Min Wook So, Aran Kim, Dong Hyun Sohn, Seung-Geun Lee","doi":"10.1080/19768354.2024.2337761","DOIUrl":"https://doi.org/10.1080/19768354.2024.2337761","url":null,"abstract":"Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by skin and internal organ fibrosis and obliterative vasculopathy. Few effective treatments are currently available for fibros...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"9 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140625788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of aerobic exercise and particulate matter exposure duration on the diversity of gut microbiota 有氧运动和颗粒物暴露时间对肠道微生物群多样性的影响
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-04-08 DOI: 10.1080/19768354.2024.2338855
Saba Imdad, Jin-Hee Kim, Byunghun So, Junho Jang, Jinhan Park, Wonchung Lim, Yoon-Kwang Lee, Woo Shik Shin, Trae Hillyer, Chounghun Kang
{"title":"Effect of aerobic exercise and particulate matter exposure duration on the diversity of gut microbiota","authors":"Saba Imdad, Jin-Hee Kim, Byunghun So, Junho Jang, Jinhan Park, Wonchung Lim, Yoon-Kwang Lee, Woo Shik Shin, Trae Hillyer, Chounghun Kang","doi":"10.1080/19768354.2024.2338855","DOIUrl":"https://doi.org/10.1080/19768354.2024.2338855","url":null,"abstract":"Inhalation of ambient particulate matter (PM) can disrupt the gut microbiome, while exercise independently influences the gut microbiome by promoting beneficial bacteria. In this study, we analyzed...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"93 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140579544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reprogramming of tumor-associated macrophages by metabolites generated from tumor microenvironment 肿瘤微环境产生的代谢物对肿瘤相关巨噬细胞的重编程作用
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-04-03 DOI: 10.1080/19768354.2024.2336249
Seung Woo Kim, Chan Woo Kim, Young-Ah Moon, Hong Seok Kim
{"title":"Reprogramming of tumor-associated macrophages by metabolites generated from tumor microenvironment","authors":"Seung Woo Kim, Chan Woo Kim, Young-Ah Moon, Hong Seok Kim","doi":"10.1080/19768354.2024.2336249","DOIUrl":"https://doi.org/10.1080/19768354.2024.2336249","url":null,"abstract":"The tumor microenvironment comprises both tumor and non-tumor stromal cells, including tumor-associated macrophages (TAMs), endothelial cells, and carcinoma-associated fibroblasts. TAMs, major comp...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"49 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140586989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tortoise-shell glue ameliorates male infertility through the hypothalamic-pituitary-gonadal axis in obese rats 龟甲胶通过下丘脑-垂体-性腺轴改善肥胖大鼠的雄性不育症
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-03-15 DOI: 10.1080/19768354.2024.2329684
Wen Sheng, Yingqiu Li, Lumei Liu, Bonan Li, Tiansong Sun, Congxu Zhu, Qinghu He
{"title":"Tortoise-shell glue ameliorates male infertility through the hypothalamic-pituitary-gonadal axis in obese rats","authors":"Wen Sheng, Yingqiu Li, Lumei Liu, Bonan Li, Tiansong Sun, Congxu Zhu, Qinghu He","doi":"10.1080/19768354.2024.2329684","DOIUrl":"https://doi.org/10.1080/19768354.2024.2329684","url":null,"abstract":"Male infertility is a worldwide population health concern, but its etiology remains poorly understood. Tortoise-shell glue (TSG) is widely utilized as a pharmaceutical or dietary supplement for var...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"46 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140146563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of MEIS1 TALE homeodomain transcription factor knockdown on glioma stem cell growth. MEIS1 TALE同源转录因子敲除对胶质瘤干细胞生长的影响
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-03-13 eCollection Date: 2024-01-01 DOI: 10.1080/19768354.2024.2327340
Hyun-Jin Kim, Don Carlo Batara, Young-Jun Jeon, Seongsoo Lee, Samuel Beck, Sung-Hak Kim
{"title":"The impact of <i>MEIS1</i> TALE homeodomain transcription factor knockdown on glioma stem cell growth.","authors":"Hyun-Jin Kim, Don Carlo Batara, Young-Jun Jeon, Seongsoo Lee, Samuel Beck, Sung-Hak Kim","doi":"10.1080/19768354.2024.2327340","DOIUrl":"10.1080/19768354.2024.2327340","url":null,"abstract":"<p><p>Myeloid ecotropic virus insertion site 1 (<i>MEIS1</i>) is a HOX co-factor necessary for organ development and normal hematopoiesis. Recently, <i>MEIS1</i> has been linked to the development and progression of various cancers. However, its role in gliomagenesis particularly on glioma stem cells (GSCs) remains unclear. Here, we demonstrate that <i>MEIS1</i> is highly upregulated in GSCs compared to normal, and glioma cells and to its differentiated counterparts. Inhibition of <i>MEIS1</i> expression by shRNA significantly reduced GSC growth in both <i>in vitro</i> and <i>in vivo</i> experiments. On the other hand, integrated transcriptomics analyses of glioma datasets revealed that <i>MEIS1</i> expression is correlated to cell cycle-related genes. Clinical data analysis revealed that <i>MEIS1</i> expression is elevated in high-grade gliomas, and patients with high <i>MEIS1</i> levels have poorer overall survival outcomes. The findings suggest that <i>MEIS1</i> is a prognostic biomarker for glioma patients and a possible target for developing novel therapeutic strategies against GBM.</p>","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"28 1","pages":"93-109"},"PeriodicalIF":2.9,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140130558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors affecting the cleavage efficiency of the CRISPR-Cas9 system. 影响 CRISPR-Cas9 系统切割效率的因素。
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-03-03 eCollection Date: 2024-01-01 DOI: 10.1080/19768354.2024.2322054
Won Jun Jung, Soo-Ji Park, Seongkwang Cha, Kyoungmi Kim
{"title":"Factors affecting the cleavage efficiency of the CRISPR-Cas9 system.","authors":"Won Jun Jung, Soo-Ji Park, Seongkwang Cha, Kyoungmi Kim","doi":"10.1080/19768354.2024.2322054","DOIUrl":"10.1080/19768354.2024.2322054","url":null,"abstract":"<p><p>The CRISPR-Cas system stands out as a promising genome editing tool due to its cost-effectiveness and time efficiency compared to other methods. This system has tremendous potential for treating various diseases, including genetic disorders and cancer, and promotes therapeutic research for a wide range of genetic diseases. Additionally, the CRISPR-Cas system simplifies the generation of animal models, offering a more accessible alternative to traditional methods. The CRISPR-Cas9 system can be used to cleave target DNA strands that need to be corrected, causing double-strand breaks (DSBs). DNA with DSBs can then be recovered by the DNA repair pathway that the CRISPR-Cas9 system uses to edit target gene sequences. High cleavage efficiency of the CRISPR-Cas9 system is thus imperative for effective gene editing. Herein, we explore several factors affecting the cleavage efficiency of the CRISPR-Cas9 system. These factors include the GC content of the protospacer-adjacent motif (PAM) proximal and distal regions, single-guide RNA (sgRNA) properties, and chromatin state. These considerations contribute to the efficiency of genome editing.</p>","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"28 1","pages":"75-83"},"PeriodicalIF":2.9,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140027187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inducing aortic aneurysm/dissection in zebrafish: evaluating the efficacy of β-Aminopropionic Nitrile as a model 诱发斑马鱼主动脉瘤/夹层：评估β-氨基丙腈作为模型的功效
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-03-01 DOI: 10.1080/19768354.2024.2322055
Jiarui Zhang, Yaowen Liang, Weiyue Zeng, Xiaoyan Gao, Dingchen Wang, Cong Mai, Zhuoheng Lin, Haishan Zhao, Xin Li
{"title":"Inducing aortic aneurysm/dissection in zebrafish: evaluating the efficacy of β-Aminopropionic Nitrile as a model","authors":"Jiarui Zhang, Yaowen Liang, Weiyue Zeng, Xiaoyan Gao, Dingchen Wang, Cong Mai, Zhuoheng Lin, Haishan Zhao, Xin Li","doi":"10.1080/19768354.2024.2322055","DOIUrl":"https://doi.org/10.1080/19768354.2024.2322055","url":null,"abstract":"Aortic aneurysm/dissection (AAD) poses a life-threatening cardiovascular emergency with complex mechanisms and a notably high mortality rate. Zebrafish (Danio rerio) serve as valuable models for AA...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"80 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140016633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcriptional corepressor activity of CtBP1 is regulated by ISG15 modification CtBP1 的转录核心抑制因子活性受 ISG15 修饰调节
IF 2.9 2区 生物学
Animal Cells and Systems Pub Date : 2024-02-22 DOI: 10.1080/19768354.2024.2321354
Yun Hwan Lim, Yoon Jin Park, Jieun Lee, Jung Hwa Kim
{"title":"Transcriptional corepressor activity of CtBP1 is regulated by ISG15 modification","authors":"Yun Hwan Lim, Yoon Jin Park, Jieun Lee, Jung Hwa Kim","doi":"10.1080/19768354.2024.2321354","DOIUrl":"https://doi.org/10.1080/19768354.2024.2321354","url":null,"abstract":"C-terminal binding protein 1 (CtBP1) is a critical transcriptional corepressor of many tumor suppressor genes and plays diverse roles in the progression of cancers. The transcriptional repression f...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"17 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139921693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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