Animal Cells and SystemsPub Date : 2024-01-29eCollection Date: 2024-01-01DOI: 10.1080/19768354.2024.2302529
Eun-Jeong Kim, Donggu Jeon, Yeon-Jeong Park, Hyunmin Woo, Seong-Il Eyun
{"title":"Dietary exposure of the water flea <i>Daphnia galeata</i> to microcystin-LR.","authors":"Eun-Jeong Kim, Donggu Jeon, Yeon-Jeong Park, Hyunmin Woo, Seong-Il Eyun","doi":"10.1080/19768354.2024.2302529","DOIUrl":"10.1080/19768354.2024.2302529","url":null,"abstract":"<p><p>Harmful substances like the cyanotoxin microcystin-leucine-arginine (MC-LR) are commonly found in eutrophic freshwater environments, posing risks to aquatic organisms. The water flea, <i>Daphnia</i>, is a well-established model organism for environmental toxicology research. Nevertheless, there is currently insufficient research on the genes that respond to MC-LR in <i>Daphnia galeata</i>. This study aimed to gain insights into the notable genes that react significantly to MC-LR. In this study, we generated an extensive RNA-Seq sequences isolated from the <i>D</i>. <i>galeata</i> HK strain, Han River in Korea. This strain was nourished with a diet of the green microalga <i>Chlorella vulgaris</i> and treated with pure MC-LR at a concentration of 36 ug/L. The transcriptome profile in response to the MC-LR treatment was obtained and 336 differentially expressed genes were subjected to Gene Ontology (GO) and euKaryotic Orthologous Groups of proteins analyses. GO enrichment analysis showed that chemical stimulus, amino sugar metabolic and catabolic process, oxidative stress, and detoxification were highly enriched, in reverse, proteolysis and fucosylation were underpresented. Detoxification process related genes such as peroxidase-like, chorion, and thyroid peroxidase-like were enriched for eliminating or neutralizing MC_LR from an organism's body. Furthermore, functional protein classification revealed an upregulation of lipid and inorganic ion transport processes, while amino acid and carbohydrate transport processes were found to be downregulated. These findings offer insights into how organisms respond to ecotoxic stimuli, providing valuable information for understanding adaptation or defense pathways.</p>","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"28 1","pages":"25-36"},"PeriodicalIF":2.5,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10829830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eugenol ameliorates uveitis in mice with experimental autoimmune encephalomyelitis through the suppression of key inflammatory genes","authors":"Sungmoo Hong, Kyungsook Jung, Meejung Ahn, Jeongtae Kim, Changjong Moon, Taekyun Shin","doi":"10.1080/19768354.2024.2304557","DOIUrl":"https://doi.org/10.1080/19768354.2024.2304557","url":null,"abstract":"Visual impairment associated with uveitis is among the potential complications in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Bioinformatics analy...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"10 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139497257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soonjae Hwang, Sangbin Park, Jaewan Kim, Ah-Reum Oh, Ho-Jae Lee, Ji-Young Cha
{"title":"Role of Carbohydrate response element-binding protein in mediating dexamethasone-induced glucose transporter 5 expression in Caco-2BBE cells and during the developmental phase in mice","authors":"Soonjae Hwang, Sangbin Park, Jaewan Kim, Ah-Reum Oh, Ho-Jae Lee, Ji-Young Cha","doi":"10.1080/19768354.2023.2301009","DOIUrl":"https://doi.org/10.1080/19768354.2023.2301009","url":null,"abstract":"Glucose transporter 5 (GLUT5), the main fructose transporter in mammals, is primarily responsible for absorbing dietary fructose in the small intestine. The expression of this intestinal gene signi...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"29 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139105053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dawn Lee, Heeyoung Lee, Ha-neul Jo, Eunsik Yun, Byung Su Kwon, Jongmin Kim, Aram Lee
{"title":"Endothelial periostin regulates vascular remodeling by promoting endothelial dysfunction in pulmonary arterial hypertension","authors":"Dawn Lee, Heeyoung Lee, Ha-neul Jo, Eunsik Yun, Byung Su Kwon, Jongmin Kim, Aram Lee","doi":"10.1080/19768354.2023.2300437","DOIUrl":"https://doi.org/10.1080/19768354.2023.2300437","url":null,"abstract":"Pulmonary arterial hypertension (PAH) is characterized by vascular remodeling associated with extracellular matrix (ECM) deposition, vascular cell hyperproliferation, and neointima formation in the...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"28 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139082283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bohye Kim, Joong-Sun Kim, BuHyun Youn, Changjong Moon
{"title":"Dopamine depletion alters neuroplasticity-related signaling in the rat hippocampus","authors":"Bohye Kim, Joong-Sun Kim, BuHyun Youn, Changjong Moon","doi":"10.1080/19768354.2023.2294308","DOIUrl":"https://doi.org/10.1080/19768354.2023.2294308","url":null,"abstract":"Dopamine (DA) plays a significant role in regulating hippocampal function, particularly in modulating synaptic plasticity. Despite this, a comprehensive understanding of the molecular mechanisms in...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"292 1 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138683170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Core clock gene, Bmal1, is required for optimal second-level interval production","authors":"Yoon Kyoung Kim, Han Kyoung Choe","doi":"10.1080/19768354.2023.2290827","DOIUrl":"https://doi.org/10.1080/19768354.2023.2290827","url":null,"abstract":"Perception and production of second-level temporal intervals are critical in several behavioral and cognitive processes, including adaptive anticipation, motor control, and social communication. Th...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"10 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138683037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaein Park, Jae-Hyun Jang, Jun-Dong Wei, Jae-Hong Kim
{"title":"The 5-/12-lipoxygenase-BLT2 cascade induces elevated expression of c-Myc, thus mediating the proliferation and migration of KRAS mutant colorectal cancer cells","authors":"Jaein Park, Jae-Hyun Jang, Jun-Dong Wei, Jae-Hong Kim","doi":"10.1080/19768354.2023.2290031","DOIUrl":"https://doi.org/10.1080/19768354.2023.2290031","url":null,"abstract":"Colorectal cancer (CRC) is the most common malignant tumor and one of the leading causes of cancer-related death worldwide. Oncogene KRAS is a commonly mutated in CRC and plays crucial roles in the...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"58 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138567372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plate-curving cell culture as a model for assessing curvature-induced cellular responses during neural tube morphogenesis","authors":"Hyung-Min Ahn, Woong Sun","doi":"10.1080/19768354.2023.2287085","DOIUrl":"https://doi.org/10.1080/19768354.2023.2287085","url":null,"abstract":"Neurulation is an important shape-transforming event during embryonic development where a flat neural plate is converted into a neural tube. Failure in this morphogenetic process accounts for one o...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"96 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138567416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joon Bum Kim, Ji-Eun Bae, Na Yeon Park, Doo Sin Jo, Yong Hwan Kim, Kwiwan Jeong, Pansoo Kim, Won-Ha Lee, Eunbyul Yeom, Dong-Hyung Cho
{"title":"Inhibition of ubiquitin specific peptidase 14 (USP14) promotes ER-phagy by inducing ER stress in human hepatoma HepG2 cells","authors":"Joon Bum Kim, Ji-Eun Bae, Na Yeon Park, Doo Sin Jo, Yong Hwan Kim, Kwiwan Jeong, Pansoo Kim, Won-Ha Lee, Eunbyul Yeom, Dong-Hyung Cho","doi":"10.1080/19768354.2023.2285825","DOIUrl":"https://doi.org/10.1080/19768354.2023.2285825","url":null,"abstract":"Autophagy plays a critical role in regulating the quality and quantity of cellular compartments; however, the mechanisms governing endoplasmic reticulum (ER) autophagy (ER-phagy) are still largely ...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"8 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic structure of Rhodeus sinensis reflects historical imprints of East Asian paleo-drainages","authors":"Hyung-Bae Jeon, Ho Young Suk","doi":"10.1080/19768354.2023.2285829","DOIUrl":"https://doi.org/10.1080/19768354.2023.2285829","url":null,"abstract":"A complete reconstruction of the history regarding the distribution of a species requires a separate analysis of the events before and after colonizing the current distribution. In a freshwater spe...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"AES-20 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}