Food & Function最新文献

{"title":"Lactobacillus complex fermentation of whey protein to reduce foodborne allergy symptoms in mice","authors":"Qinggang Xie, Chunyi Zhai, Shengjun Yang, Xiangxin Wang, Ting Cao, Bailiang Li, Xiaoxi Xu and Zhongjiang Wang","doi":"10.1039/D4FO05988C","DOIUrl":"10.1039/D4FO05988C","url":null,"abstract":"<p >Bovine whey protein, a common ingredient in foods for infants and young children, represents the primary source of nutrition for this demographic. However, bovine whey protein contains β-lactoglobulin (β-LG), which is not found in human whey protein, and some α-lactalbumin (α-LA) with a different amino acid sequence, which has the potential to cause allergic reactions. Eating bovine whey protein can cause allergic reactions in the human immune system. This phenomenon refers to an allergy to bovine whey protein. It is estimated that this condition affects 1.9% to 4.9% of infants globally. <em>Lactobacilli</em> possess a robust protein hydrolysis system capable of disrupting epitopes associated with whey protein allergies while yielding hydrolyzed products and bioactive peptides. This process represents a safe and effective approach to reducing the allergenicity of milk. Consequently, we established a mouse model for whey protein allergy and evaluated the effects of fermented whey protein produced by <em>Lactobacillus</em> on allergic symptoms in mice using ELISA, real-time fluorescence quantitative PCR (RT-qPCR), and HE staining techniques. Furthermore, we analyzed the intestinal flora of allergic mice through 16S rDNA sequencing to elucidate the relationship between <em>Lactobacillus</em>-mediated alterations in gut microbiota and allergic phenotypes within this study. The results showed that compared with the whey protein group, the levels of immunoglobulin E (IgE), histamine and mast cell protease in the serum of mice in the lactic acid bacteria fermented whey protein group were significantly increased, and the secretion of T helper 2 (Th2) type cytokines was inhibited, the production of T helper 1 (Th1) type cytokines was promoted, and the inflammation caused by sensitized mice was significantly alleviated. Furthermore, the fermentation of whey protein by <em>Lactobacillus</em> resulted in an improvement in the intestinal flora of mice, accompanied by promotion of the growth of probiotics such as <em>Lactobacillus</em>, <em>Odoribacter</em> and <em>Bacteroides</em>. This effectively alleviated the allergic reaction in mice. The findings of this experiment provide a theoretical basis for the development of hypoallergenic dairy products and offer a certain degree of guidance for the clinical treatment of allergic diseases.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3152-3165"},"PeriodicalIF":5.1,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lycopene improves cisplatin induced hepatointestinal injury in rats by modulating the microbe–gut–liver axis†","authors":"Enshuang Xu, Zhiying Yu and Jiasan Zheng","doi":"10.1039/D4FO06059H","DOIUrl":"10.1039/D4FO06059H","url":null,"abstract":"<p >Cisplatin (CIS) is a commonly used antitumor drug in clinics, but its application is limited due to hepatotoxicity, nephrotoxicity and gastrointestinal toxicity. In recent years, a large number of studies have shown that the imbalance of intestinal flora is one of the important factors in the malignant development of diseases. Therefore, improving organ function by regulating intestinal flora may be an important strategy to prevent the side effects of chemotherapy drugs. Lycopene (LYC) is found in a wide range of red foods and has antioxidant, anti-inflammatory and immune-enhancing effects. So the purpose of this study was to explore its effect on hepatointestinal injury caused by chemotherapy drugs. The results of this study showed that CIS could significantly restore body weight, diet, water intake, and AST, ALT and other physiological and biochemical indexes of rats. HE staining, projective electron microscopy and TUNEL results showed that LYC alleviated morphological and ultrastructural damage of the liver and intestine. Then, ELISA results showed that LYC can reduce cell apoptosis by increasing the antioxidant capacity and reducing inflammatory response. Secondly, 16sRNA and metabolome results showed that LYC enriched beneficial bacteria (Firmicutes and Proteobacteria), reduced harmful bacteria (<em>E. coli</em>, <em>etc</em>.), enhanced metabolic pathway changes such as taurine and hypotaurine metabolism, and alleviated organ damage caused by CIS. Finally, network pharmacology, molecular docking and immunohistochemistry showed that LYC could reduce CIS induced hepatocyte inflammation and apoptosis by activating the PI3K/AKT pathway. In summary, LYC alleviates the toxic side effects of chemotherapy drugs by regulating the PI3K/AKT pathway and the intestinal microbiota–metabolite–liver axis.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3064-3074"},"PeriodicalIF":5.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Bifidobacterium breve</i> HH079 alleviates early-life antibiotic-exposed colon dysbiosis in mice by restoring the gut microbiota and gut barrier function.","authors":"Zhipeng Gu, Zerong Lu, Jian-Yong Wu, Zhuqing Xie, Ruibiao Hu, Qiang Huang, Feitong Liu, Bin Zhang","doi":"10.1039/d5fo00535c","DOIUrl":"https://doi.org/10.1039/d5fo00535c","url":null,"abstract":"<p><p>Antibiotic exposure in early life disrupts gut microbiota development in infants, which could result in intestinal dysfunction. This study mimicked early-life antibiotic exposure in mice by administering antibiotic water to lactating dams, and investigated the effects of a new strain of <i>Bifidobacterium breve</i> HH079 (<i>B. breve</i> HH079) on intestinal dysbiosis associated with early-life antibiotic exposure in pups. The results showed that <i>B. breve</i> HH079 treatment inhibited the proliferation of <i>Pseudomonas</i> and <i>Morganella</i> after antibiotic exposure, but promoted the abundance of <i>Bifidobacterium</i> and <i>Bacteroides</i> and acetate production. Concomitantly, the <i>B. breve</i> HH079 administration resulted in decreased M1 gene (<i>Cd86</i>) and protein (TNF-α, IL-1β, LBP and iNOS) expression and increased M2 macrophage marker (<i>Cd206</i>, IL-10 and Arg1) expression in the colonic macrophages of antibiotic-exposed pups, probably by inhibiting the TLR4/NF-κB pathway. Moreover, there was increased intestinal epithelial tight junction protein (Cldn1 and Ocln) expression and the transcription of marker gene (<i>Lyz2</i>, <i>Igha</i> and <i>Reg3β</i>) normalization involved in innate immunity. The results suggested that the new <i>B. breve</i> HH079 strain could alleviate early-life antibiotic-induced colon dysbiosis by regulating the gut microbiota and promoting acetate production and the subsequent M2 macrophage polarization to recover gut health.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of cecal metabolites and DNA methylation in deciphering the effects of maternal genistein intake on white fat browning in adult female offspring†","authors":"Shunhua Li, Liyuan Zhou, Jing Ren, Jieying Liu, Qian Zhang and Xinhua Xiao","doi":"10.1039/D4FO04761C","DOIUrl":"10.1039/D4FO04761C","url":null,"abstract":"<p >Maternal diets during pregnancy and lactation are critical determinants that regulate the metabolic homeostasis in offspring. Our previous research demonstrated that maternal genistein (GEN) intervention ameliorated the dysregulation of glucolipid metabolism induced by intrauterine overnutrition in adult offspring, accompanied by changes in the composition of gut microbiota; however, the underlying mechanisms remain unclear. Here, we used a maternal overnutrition model induced by excess energy intake before and throughout pregnancy and lactation, with maternal GEN administered during the same period. The female offspring were raised on a standard chow diet until sacrificed at 24 weeks. The mRNA levels of browning markers were quantified in inguinal subcutaneous adipose tissues, followed by methylation analysis <em>via</em> the MassArray method. Cecal contents were collected for untargeted metabolomic analysis and a target quantitative analysis of methionine cycle metabolites. Spearman correlation analyses were used to assess whether cecal metabolites are involved in the methylation of browning-related genes and influence their expression. The results showed that maternal GEN supplementation reversed the downregulation of browning markers caused by perinatal high-fat diets in adult female offspring, consistent with a reduction in their methylation levels. Subsequently, we also found that maternal GEN consumption altered cecal metabolite profiles in offspring, promoting the production of bile acids, potent regulators of glucolipid metabolism, and reducing metabolites involved in the methionine cycle, key methyl donors for the methylation process. Furthermore, the abundances of these metabolites were significantly correlated with the methylation and expression levels of browning markers. Overall, this discovery suggested that maternal GEN intake decreased the methylation level of browning markers and induced browning in white adipose tissue of offspring, which correlated with alterations in cecal metabolites. We provide a novel theoretical basis for GEN as a promising nutritional supplement to break the vicious cycle of maternal metabolic disturbances being transmitted to offspring.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3090-3100"},"PeriodicalIF":5.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive peptides from barley protein hydrolysate stimulate cholecystokinin secretion via calcium-sensing receptor signaling in enteroendocrine cells","authors":"Hongdong Song, Lei Xue, Zhuwei Shao, Qiuyun Fu, Hongwei Cao, Kai Huang and Xiao Guan","doi":"10.1039/D5FO00298B","DOIUrl":"10.1039/D5FO00298B","url":null,"abstract":"<p >Anorexigenic hormone cholecystokinin (CCK), secreted by enteroendocrine cells (EECs), is known for its inhibitory role in appetite. The secretion of CCK is greatly affected by dietary ingredients. The search for functional components in food that stimulate CCK secretion is of great significance for weight control. Our previous study has demonstrated that barley protein hydrolysate (BPH) strongly stimulates CCK secretion from EECs <em>in vitro</em>, but the structural characteristics of the responsible components and their underlying mechanism of action have not yet been elucidated. Here, we monitor the plasma levels of CCK in mice after ingestion of BPH to demonstrate its <em>in vivo</em> activity in stimulating CCK secretion. Using size exclusion column chromatography and liquid chromatography-tandem mass spectrometry, we isolate and identify three novel CCK secretion-stimulating peptides, including VQVQIPF, VVTGVGGQ and PQQPQPFFQ. Among them, the peptide VVTGVGGQ exhibits the strongest activity in stimulating CCK secretion. Inhibition experiments show that the calcium-sensing receptor (CaSR) is required for VVTGVGGQ to increase CCK gene transcription and secretion. Blockage of CaSR by NPS-2143 completely abolishes the activity of VVTGVGGQ. Moreover, the downstream signaling molecules including CaSR coupled G-protein subtype G<small>_q</small> and intracellular Ca<small>²⁺</small> are also involved in VVTGVGGQ-stimulated CCK secretion. Inhibition of G<small>_q</small> and intracellular Ca<small>²⁺</small> completely and partially abolish this peptide-induced CCK secretion, respectively. Our findings highlight the potential of barley protein-derived hydrolysate and peptides as functional food ingredients for CCK secretion stimulation and weight control.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3018-3027"},"PeriodicalIF":5.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cynarin protects against seizures and neuronal death in a rat model of kainic acid-induced seizures†","authors":"Cheng-Wei Lu, Tzu-Yu Lin, Wun-Jing Pan, Kuan-Ming Chiu, Ming-Yi Lee and Su-Jane Wang","doi":"10.1039/D4FO05464D","DOIUrl":"10.1039/D4FO05464D","url":null,"abstract":"<p >The potential therapeutic value of cynarin, a phenolic compound derived from artichoke, in treating epilepsy has not yet been reported. The present study evaluated the effects of cynarin on a kainic acid (KA)-induced seizure rat model and its potential mechanism. Cynarin was administered through oral gavage at a dosage of 10 mg kg<small>⁻¹</small> daily for 7 days before the induction of seizures with KA (15 mg kg<small>⁻¹</small>) <em>via</em> intraperitoneal injection. The results showed that pretreatment with cynarin effectively attenuated the KA-induced seizure score and electroencephalogram (EEG) changes and prevented neuronal loss and glial cell activation in the hippocampi of KA-treated rats. In addition, pretreatment with cynarin dramatically prevented the aberrant levels of high mobility group box 1 (HMGB1), toll-like receptor-4 (TLR4), p-IκB, p65-NFκB, interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor (TNF-α) induced by KA administration in hippocampal tissues. Additionally, KA substantially increased hippocampal glutamate levels and decreased cerebral blood flow, which were significantly alleviated by pretreatment with cynarin. The observed effects of cynarin were comparable to those of the antiepileptic drug carbamazepine (CBZ). Furthermore, there was no significant difference in the serum AST, ALT, creatinine, or bilirubin levels between the cynarin-treated rats and the control rats. Cynarin has a neuroprotective effect on a rat model of seizures induced by KA, reducing seizures, gliosis, inflammatory cytokines, and glutamate elevation and increasing cerebral blood flow. Thus, cynarin has therapeutic potential for preventing epilepsy.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3048-3063"},"PeriodicalIF":5.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phlorizin mitigates high glucose-induced metabolic disorders through the IIS pathway in Caenorhabditis elegans†","authors":"Qi Gu, Chenlu Wang, Han Huang, Dandan Wei, Lina Fu, Guosheng Liu, Quan Zhou, Jie Yang and Yujie Fu","doi":"10.1039/D4FO04519J","DOIUrl":"10.1039/D4FO04519J","url":null,"abstract":"<p >Phlorizin is a dihydrochalcone with various biological activities. To elucidate the mechanism of mitigating high glucose-induced metabolic disorders by phlorizin, the integrated approach combining metabolomics and gene expression profiling was used. The results demonstrated that phlorizin effectively mitigated the impact of high glucose on various growth indicators of <em>C. elegans</em>, as well as decreased lipofuscin, ROS, glucose and triglyceride levels. Metabolomics analysis revealed that phlorizin significantly affected the metabolic pathways of carbohydrates, lipids, and amino acids in <em>C. elegans</em>, indicating its potential role in maintaining energy homeostasis. Gene expression analysis indicated that phlorizin reversed the downregulation of IIS, mTOR and lipid metabolism pathways and promoted the nuclear translocation of DAF-16. In the <em>C. elegans</em> mutant BQ1, the effect of phlorizin on lowering glucose and triglyceride levels was eliminated, meaning that AKT-1 was found to be a key target protein for phlorizin's hypoglycemic and lipid-lowering effects. Molecular docking results also indicated a strong interaction between phlorizin and AKT-1 protein. In summary, phlorizin alleviated metabolic disorders and gene expression imbalances induced by high glucose, and AKT-1 was first found as the key target protein for phlorizin achieving hypoglycemic and hypolipidemic effects.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3004-3017"},"PeriodicalIF":5.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential of queen bee larvae as a dietary supplement for obesity management: modulating the gut microbiota and promoting liver lipid metabolism.","authors":"Zhuang Li, Yiang Chen, Tengfei Shi, Haiqun Cao, Guijie Chen, Linsheng Yu","doi":"10.1039/d5fo00166h","DOIUrl":"https://doi.org/10.1039/d5fo00166h","url":null,"abstract":"<p><p>Queen bee larvae (QBL) have been consumed as both a traditional food and medicine in China for thousands of years; however, their specific benefits for human health, particularly their potential anti-obesity property, remain underexplored. This study investigated the anti-obesity effect of QBL freeze-dried powder (QBLF) on high-fat diet (HFD) induced obesity in mice and explored the underlying mechanisms. Our findings showed that QBLF effectively reduced body weight, fasting blood glucose levels, lipid accumulation, and inflammation in HFD mice. 16S rRNA sequencing revealed that QBLF significantly modulated the gut microbiota disrupted by an HFD, notably increasing the relative abundance of beneficial microbes such as <i>Ileibacterium</i>, <i>Clostridium sensu stricto 1</i>, <i>Incertae sedis</i>, <i>Streptococcus</i>, <i>Lactococcus</i>, <i>Clostridia UCG-014</i>, and <i>Lachnospiraceae UCG-006</i>, which were inversely associated with obesity-related phenotypes in the mice. RNA sequencing analysis further demonstrated that QBLF intervention upregulated the expression of genes involved in liver lipid metabolism, including <i>Pck1</i>, <i>Cyp4a10</i>, <i>Cyp4a14</i>, and <i>G6pc</i>, while downregulating genes associated with the inflammatory response, such as <i>Cxcl10</i>, <i>Ccl2</i>, <i>Traf1</i>, <i>Mapk15</i>, <i>Lcn2</i>, and <i>Fosb</i>. These results suggested that QBLF can ameliorate HFD-induced obesity through regulating the gut microbiota, promoting liver lipid metabolism, and reducing inflammatory response.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lactic acid bacteria target NF-κB signaling to alleviate gastric inflammation","authors":"Shiying Wu, Yuenuo Luo, Fangtong Wei, Yanan Li, Jiayi Fan, Yongqiang Chen, Wenjie Zhang, Xuelong Li, Yang Xu, Ziqi Chen, Chenlan Xia, Mingyang Hu, Ping Li and Qing Gu","doi":"10.1039/D4FO06308B","DOIUrl":"10.1039/D4FO06308B","url":null,"abstract":"<p > <em>Helicobacter pylori</em> (<em>H. pylori</em>) infection and the resulting gastric inflammation are major contributors to gastric cancer development. Probiotics, particularly <em>Lactobacillus</em>, are promising for their anti-inflammatory potential, yet their exact mechanisms in inhibiting <em>H. pylori</em>-induced inflammation are unclear. In our previous study, <em>Lactiplantibacillus plantarum</em> ZJ316 (<em>L. plantarum</em> ZJ316) demonstrated strong anti-inflammatory effects against <em>H. pylori</em> infection <em>in vivo</em>, but its precise mechanisms were not fully understood. Here, we aimed to investigate how <em>L. plantarum</em> ZJ316 inhibits the inflammatory response to <em>H. pylori</em> infection. Our results demonstrated that <em>L. plantarum</em> ZJ316 effectively reduced the expression of pro-inflammatory cytokines in <em>H. pylori</em>-infected AGS cells. Mechanistically, <em>L. plantarum</em> ZJ316 inhibited the NF-κB signaling pathway by preventing the degradation of IκBα, suppressing p65 phosphorylation, and blocking the nuclear translocation of phosphorylated p65. Treatment with the NF-κB inhibitor BAY 11-7082 further decreased tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), and interleukin-1β (IL-1β) levels, confirming the inhibitory effect of <em>L. plantarum</em> ZJ316 on the NF-κB pathway. In <em>H. pylori</em>-infected mice, oral administration of <em>L. plantarum</em> ZJ316 significantly alleviated inflammatory cell infiltration, reduced TNF-α and pepsinogen II (PGII) levels, and increased interleukin-10 (IL-10) levels in serum. A comparative metagenomic analysis of the gastric microbiota revealed a decrease in <em>Prevotella</em> and <em>Desulfovibrio</em>, alongside an increase in <em>Ligilactobacillus</em> and <em>Akkermansia</em>, supporting the protective effects of <em>L. plantarum</em> ZJ316 and correlating with their decreased inflammatory response. In summary, administration of <em>L. plantarum</em> ZJ316 demonstrated robust anti-inflammatory effects against <em>H. pylori</em> infection by suppressing NF-κB signaling and promoting favorable changes in the gastric microbiota composition. Therefore, <em>L. plantarum</em> ZJ316 holds promise as a novel functional food for protecting the body against <em>H. pylori</em> infection.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3101-3119"},"PeriodicalIF":5.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia","authors":"Jing Li, Jiahan Guo, Michael Yuen, Hywel Yuen and Qiang Peng","doi":"10.1039/D5FO90023A","DOIUrl":"10.1039/D5FO90023A","url":null,"abstract":"<p >Correction for ‘The comparative effects of ω-7 fatty acid-rich sea buckthorn oil and ω-3 fatty acid-rich DHA algal oil on improving high-fat diet-induced hyperlipidemia’ by Jing Li <em>et al.</em>, <em>Food Funct.</em>, 2025, <strong>16</strong>, 1241–1253, https://doi.org/10.1039/D4FO04961F.</p>","PeriodicalId":77,"journal":{"name":"Food & Function","volume":" 8","pages":" 3227-3227"},"PeriodicalIF":5.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/fo/d5fo90023a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}