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Revista espanola de oncologia最新文献

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[Ruthenium complexes as antitumor drugs: isolation of a new Ru (III) and iminodiacetic acid complex]. [钌配合物作为抗肿瘤药物:一种新的钌(III)与亚氨基二乙酸配合物的分离]。
Revista espanola de oncologia Pub Date : 1984-01-01
R Vilaplana, M G Basallote, F González-Vilchez
{"title":"[Ruthenium complexes as antitumor drugs: isolation of a new Ru (III) and iminodiacetic acid complex].","authors":"R Vilaplana,&nbsp;M G Basallote,&nbsp;F González-Vilchez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors discuss the convenience for using ruthenium complexes as potential antitumor drugs, and the considerable importance of these substances in regard to their biological activity. The synthesis of a new drug of the group and the results of its administration to mice bearing Ehrlich ascites cancer are reported.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 4","pages":"575-82"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17627992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bilateral malignant Brenner's tumor. Apropos of a case]. 双侧恶性勃勒纳瘤。关于一个案例]。
Revista espanola de oncologia Pub Date : 1984-01-01
J M Boguña Ponsao, M Medina Fernández, M A García Simón, X M Buxo Massaguer
{"title":"[Bilateral malignant Brenner's tumor. Apropos of a case].","authors":"J M Boguña Ponsao,&nbsp;M Medina Fernández,&nbsp;M A García Simón,&nbsp;X M Buxo Massaguer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This is the case of a 51 year old woman presented with sensation of pelvic fullness, hypogastric pain, anorexia, asthenia and weight loss of one year duration. The gynecological exam revealed a normal uterus and a hard oval mass in the posterior aspect of the vagina, and another spherical mass in right vaginal cul de sac and adnexial area. After surgery malignant a Brenner tumor was diagnosed. A course of chemotherapy was started postoperatively. The \"second-look\" was negative macroscopically but positive cytologically. A second course of chemotherapy was done. The second \"second-look\" was negative macroscopically and cytologically. The patient at present is in good health.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 4","pages":"631-8"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17628937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Significance of calcifications of the breast and diagnostic value of mammography]. 【乳腺钙化的意义及乳腺x线摄影的诊断价值】。
Revista espanola de oncologia Pub Date : 1984-01-01
J Sánchez Martos, M Gil Gayarre, D Espinós Pérez, M Gutiérrez Acosta
{"title":"[Significance of calcifications of the breast and diagnostic value of mammography].","authors":"J Sánchez Martos,&nbsp;M Gil Gayarre,&nbsp;D Espinós Pérez,&nbsp;M Gutiérrez Acosta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors make a revue of the value of mammography as a diagnostic technic for breast cancer, centering their attention in the existence of calcification. Based on data from the literature and on their own experience, they consider mammography to be a useful procedure for screening, allowing an early diagnosis in a significant number of cases.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 4","pages":"665-708"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17628940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Value of studying oncologic patients using bone gammagraphy for the diagnosis of skeletal metastasis. Review of 200 cases]. 骨x线摄影对肿瘤患者骨转移诊断的价值。审查200个案例]。
Revista espanola de oncologia Pub Date : 1984-01-01
O Caballero Carpena
{"title":"[Value of studying oncologic patients using bone gammagraphy for the diagnosis of skeletal metastasis. Review of 200 cases].","authors":"O Caballero Carpena","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two hundred cancer patients with bone metastases were studied by gammagraphy employing 555 MBq of 99mTc-MDP. The results were compared with those obtained by radiology and alkaline phosphatase determination, showing that gammagraphy is positive in 93 per 100 of the cases and is more useful than the other procedures to make a pre-radiologic diagnosis of bone metastases (27 per 100).</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 1","pages":"79-87"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17602563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tissue polypeptide antigen (TPA) in non-neoplastic diseases]. 组织多肽抗原(TPA)在非肿瘤性疾病中的应用。
Revista espanola de oncologia Pub Date : 1984-01-01
A Ruibal, P Durán Bellido, A Salgado, F García Bragado, J Monné, F M Domenech-Torné, L Salvador
{"title":"[Tissue polypeptide antigen (TPA) in non-neoplastic diseases].","authors":"A Ruibal,&nbsp;P Durán Bellido,&nbsp;A Salgado,&nbsp;F García Bragado,&nbsp;J Monné,&nbsp;F M Domenech-Torné,&nbsp;L Salvador","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Radioimmunoassay (TPA Prolifigen RIA) was used to determine the serum concentration of TPA in 333 patients with different kinds of non-tumoral diseases. Amounts higher than 90 U/l, that was taken as the upper normal limit, were observed in 40 per 100 of the cases, being higher than 200 U/l in 10 per 100. The frequency of abnormal amounts of TPA in non-tumoral diseases obliges to eliminate them before making a diagnosis of cancer.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 3","pages":"421-5"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17602666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enzymes of neutrophils in workers occupationally exposed to benzene, toluene and xylene. 职业性接触苯、甲苯和二甲苯工人中性粒细胞的酶。
Revista espanola de oncologia Pub Date : 1984-01-01
P Moszczyński, J Lisiewicz
{"title":"Enzymes of neutrophils in workers occupationally exposed to benzene, toluene and xylene.","authors":"P Moszczyński,&nbsp;J Lisiewicz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histochemical studies of peripheral blood neutrophils have been performed in 106 workers occupationally exposed to benzene, toluene and xylene. The benzene, toluene and xylene concentrations in the air at work places ranged from 0-370, 0-580 and 0-560 mg/cu.m, respectively. It as been stated that the initial period of exposure is characterized by adaptative reactions of neutrophils expressed in increased intracellular activity of acid hydrolases and diminished glycogen reserve. The advanced period of exposure, that is after 55 months of exposure, is associated with some signs of decreased biological deficiency of neutrophils expressed in lowering the activity of selected enzymes and accumulation of both glycogen and lipids. According to the authors opinion the evaluation of the enzymatic content of neutrophils may be helpful in monitoring the toxic effects of benzene and its homologues in industrial workers.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 3","pages":"435-41"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17167585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Possible interactions between Toxoplasma gondii infection and the presence of non-Hodgkin's lymphoma]. [弓形虫感染与非霍奇金淋巴瘤之间可能存在的相互作用]。
Revista espanola de oncologia Pub Date : 1984-01-01
A B Ortiz-Muñoz, L Cuadrado-Méndez, R Sanchis-Belenguer
{"title":"[Possible interactions between Toxoplasma gondii infection and the presence of non-Hodgkin's lymphoma].","authors":"A B Ortiz-Muñoz,&nbsp;L Cuadrado-Méndez,&nbsp;R Sanchis-Belenguer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The presence of antibodies to Toxoplasma gondii was studied in the sera of 63 patients with non-Hodgkin lymphoma. After the age of 30 years, antibodies to the parasite increase progressively in the whole population, but the incidence and titer are significantly higher in non-Hodgkin lymphoma patients. After the chemotherapy treatment, the titer of the antibodies to Toxoplasma gondii augment-ed.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 2","pages":"237-45"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17458657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment with intratumoral prospidium chloride of cancer of the mammae induced by N-nitrosomethylurea in the rat]. [n -亚硝基somethylurea诱导的大鼠乳腺癌瘤内氯化钾治疗]。
Revista espanola de oncologia Pub Date : 1984-01-01
M Urcia, M C Leal, L Lafarga, V Guillén, J Hergueta, F R Pérez-López
{"title":"[Treatment with intratumoral prospidium chloride of cancer of the mammae induced by N-nitrosomethylurea in the rat].","authors":"M Urcia,&nbsp;M C Leal,&nbsp;L Lafarga,&nbsp;V Guillén,&nbsp;J Hergueta,&nbsp;F R Pérez-López","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Wistar rats bearing N-nitrosomethylurea-induced mammary tumors received intratumoral injections of prospidium chloride or saline. Each tumor with 30-100 mm2 (the product of the two largest perpendicular diameters) received 20 mg of prospidium chloride diluted in 100 microliter of saline, and increasing amounts of 20 mg of the product in the same volume for every additional 100 mm2 or fraction of tumor. After a week the treatment was repeated in the same way. Control rats received only saline without prospidium chloride. No significant differences were observed regarding the tumor area, total tumor area/rat, and body weight when comparing the rats receiving prospidium chloride and the control rats. Prospidium chloride does not show any direct oncolytic effect upon the experimental model employed.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 4","pages":"601-4"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17628934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Platinum complexes as radiosensitizers in radiotherapy]. [铂配合物在放射治疗中的放射增敏剂]。
Revista espanola de oncologia Pub Date : 1984-01-01
M C López Zúmel, M V Alvarez, L Santos Peinado
{"title":"[Platinum complexes as radiosensitizers in radiotherapy].","authors":"M C López Zúmel,&nbsp;M V Alvarez,&nbsp;L Santos Peinado","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors study the radiosensitizing effect of cisplatinum, cis-dichloroethylenediamine platinum (II), and cis-dichlorobis-cyclohexylamine platinum (II) by the of TC-SV40 cells radiated under aerobic and hypoxic conditions. Cis-platinum shows the highest radiosensitizing activity but is very toxic. Perhaps cis-dischloro-bis-cyclohexylamine platinum (II) could be assayed as a less toxic radiosensitizing agent. On the other hand, DNA synthesis is studied in mouse spleen and TC-SV40 cells labeled with tritiated thymidine. Cis-platinum inhibitory activity is related to the preincubation time, cis-dichloroethylenediamine platinum(II) does not inhibit the semiconservative synthesis and stimulates the repair synthesis of DNA, and cis-dichloro-bis-cyclohexylamine platinum (II) produces a 60 per 100 inhibition of the semiconservative synthesis and a smaller inhibition of the repair synthesis.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 2","pages":"227-36"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17167688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gamma-glutamyltransferase and alkaline phosphatase in the serum and saliva of patients with hepatic tumors and hepatic cirrhosis]. [肝肿瘤及肝硬化患者血清及唾液γ -谷氨酰转移酶及碱性磷酸酶]。
Revista espanola de oncologia Pub Date : 1984-01-01
J Jiménez-Alonso, L Jaimez, L Barrios, F Pérez-Jiménez, A García, R Bejarano, J L Ogea, J A Jiménez-Pereperez
{"title":"[Gamma-glutamyltransferase and alkaline phosphatase in the serum and saliva of patients with hepatic tumors and hepatic cirrhosis].","authors":"J Jiménez-Alonso,&nbsp;L Jaimez,&nbsp;L Barrios,&nbsp;F Pérez-Jiménez,&nbsp;A García,&nbsp;R Bejarano,&nbsp;J L Ogea,&nbsp;J A Jiménez-Pereperez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors have previously described the presence of gammaglutamyl transferase and alkaline phosphatase in the saliva of healthy individuals and of patients with hepatobiliary and pancreatic diseases. The authors show in this work the values of said enzymes in the blood serum and saliva of 23 cases of liver cirrhosis and 17 patients with liver tumors. Both enzymes increase significantly in the serum of liver tumor patients with respect to the amounts found in liver cirrhosis patients (p less than 0.005). Alkaline phosphatase increased significantly in the saliva of patients with liver cirrhosis (p less than 0.005), where as no differences were found between the two groups of patients with liver cirrhosis (p less than 0.005), where as no differences were found between the two groups of patients for the salivary gamma-glutamyl transferase. The determination of seric alkaline phosphatase and gamma-glutamyl transferase, and of salivary alkaline phosphatase may be useful for the differential diagnosis between liver cirrhosis and liver tumor.</p>","PeriodicalId":77791,"journal":{"name":"Revista espanola de oncologia","volume":"31 2","pages":"315-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17218598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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