Enzymes of neutrophils in workers occupationally exposed to benzene, toluene and xylene.

Revista espanola de oncologia Pub Date : 1984-01-01
P Moszczyński, J Lisiewicz
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Abstract

Histochemical studies of peripheral blood neutrophils have been performed in 106 workers occupationally exposed to benzene, toluene and xylene. The benzene, toluene and xylene concentrations in the air at work places ranged from 0-370, 0-580 and 0-560 mg/cu.m, respectively. It as been stated that the initial period of exposure is characterized by adaptative reactions of neutrophils expressed in increased intracellular activity of acid hydrolases and diminished glycogen reserve. The advanced period of exposure, that is after 55 months of exposure, is associated with some signs of decreased biological deficiency of neutrophils expressed in lowering the activity of selected enzymes and accumulation of both glycogen and lipids. According to the authors opinion the evaluation of the enzymatic content of neutrophils may be helpful in monitoring the toxic effects of benzene and its homologues in industrial workers.

职业性接触苯、甲苯和二甲苯工人中性粒细胞的酶。
对106名职业接触苯、甲苯和二甲苯的工人进行了外周血中性粒细胞的组织化学研究。工作场所空气中苯、甲苯和二甲苯的浓度范围为0-370、0-580和0-560毫克/立方米。m,分别。据报道,暴露初期的特点是中性粒细胞的适应性反应,表现为细胞内酸水解酶活性增加和糖原储备减少。暴露后期,即暴露55个月后,与中性粒细胞生物学缺陷减少的一些迹象有关,中性粒细胞的生物学缺陷表现为降低选定酶的活性和糖原和脂质的积累。评价中性粒细胞的酶促含量有助于监测苯及其同系物对工业工人的毒性作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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