{"title":"Racial equity in academia: Why Brazil still needs to be bolder in faculty hiring policies.","authors":"Wagner F Magalhães, Itan Cruz","doi":"10.1590/0001-3765202520250121","DOIUrl":"https://doi.org/10.1590/0001-3765202520250121","url":null,"abstract":"","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20250121"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas A DA Mota Santana, Gina Délia Roque-Torres, Rajiv G Gopalsamy, Lysandro P Borges, Daniel Araki Ribeiro, Virgínia K S Silva, Cleverson Luciano Trento, Wilton M Takeshita
{"title":"Assessing actinic cheilitis oncogenic potential via micronucleus assay.","authors":"Lucas A DA Mota Santana, Gina Délia Roque-Torres, Rajiv G Gopalsamy, Lysandro P Borges, Daniel Araki Ribeiro, Virgínia K S Silva, Cleverson Luciano Trento, Wilton M Takeshita","doi":"10.1590/0001-3765202520250104","DOIUrl":"https://doi.org/10.1590/0001-3765202520250104","url":null,"abstract":"","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20250104"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenji F Motoki, Thomas F C Campos, José Humberto Araujo, Anderson C Santos, Maria Elisa P Gomes, Susanna Elenora Sichel, Estefan M Fonseca, Lucas G P Monteiro, Gabriel S Nogueira
{"title":"Assessment of Surface Radiogenic Heat Flow in Volcanic Rocks of Trindade Island, South Atlantic Ocean, Brazil.","authors":"Kenji F Motoki, Thomas F C Campos, José Humberto Araujo, Anderson C Santos, Maria Elisa P Gomes, Susanna Elenora Sichel, Estefan M Fonseca, Lucas G P Monteiro, Gabriel S Nogueira","doi":"10.1590/0001-3765202520240353","DOIUrl":"https://doi.org/10.1590/0001-3765202520240353","url":null,"abstract":"<p><p>Heat loss from Earth's interior, driven by conduction and convection, influences lithospheric thermal regimes. This heat originates from mantle convection, primordial planetary accretion, and the decay of radioactive heat-producing elements (RHPE: U-238, U-235, Th-232 and K-40), which contribute around 98% of Earth's radiogenic heat production, crucial for surface radioactive heat flux (SRHF). Understanding RHPE is key to studying geothermal dynamics, especially in volcanic regions like Trindade Island, Brazil. This study aims to: Quantify U, Th, and K concentrations in volcanic soils; map their spatial distribution, detect anomalies and evaluate radiogenic heat production and flux. Three methods were used: whole-rock ICP analyses for geochemical characterization, laboratory gamma spectrometry (LabGRS), and in situ gamma spectrometry (surfGRS) for spatial coverage. A total of 77 samples and 481 measurement points were analyzed and SRHF was measured. Results show that the thorium contributes most to SRHF, providing insights into heat generation and mantle-crust volcanic interactions. This study provides critical insights into radiogenic heat generation and its role in lithospheric thermal evolution, offering a refined understanding of heat production in oceanic volcanic settings. The findings enhance geophysical and geochemical models of heat flux, contributing to broader studies on mantle-crust interactions and geothermal energy potential.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20240353"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Henrique González, Vanessa DE Almeida Guimarães, Luisa Maria Diele-Viegas
{"title":"Technological innovation for sustainable development as a catalyst for Brazil's future.","authors":"Pedro Henrique González, Vanessa DE Almeida Guimarães, Luisa Maria Diele-Viegas","doi":"10.1590/0001-3765202520250459","DOIUrl":"https://doi.org/10.1590/0001-3765202520250459","url":null,"abstract":"","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20250459"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo B DE Sousa, Renata Akemi M Matsui, Leonardo C Boldrini, Leandra S Baptista, José Mauro Granjeiro
{"title":"Mesenchymal stem cells for the treatment of articular cartilage defects of the knee: an overview of systematic reviews.","authors":"Eduardo B DE Sousa, Renata Akemi M Matsui, Leonardo C Boldrini, Leandra S Baptista, José Mauro Granjeiro","doi":"10.1590/0001-3765202520241426","DOIUrl":"https://doi.org/10.1590/0001-3765202520241426","url":null,"abstract":"<p><p>There is no consensus on the ideal type, dose, expansion, and differentiation of MSCs for treating knee cartilage defects. Our goal was to perform an overview of systematic reviews regarding the use of MSCs for the treatment of articular cartilage lesions of the knee. The overview of systematic reviews followed the Population (patients aged between 18 and 50 years with traumatic knee articular cartilage lesions), Intervention (MSCs treatment), Comparison (autologous chondrocyte implantation or microfracture), and Outcomes (magnetic resonance imaging or second-look knee arthroscopy) matrix. No language restrictions were applied. We assessed methodological quality, reporting standards, and evidence levels. A total of 529 records were retrieved from six databases. After duplicate removal and eligibility screening, nine systematic reviews were included, and three were updated with recent data. Most reviews suggested a positive effect of MSCs on cartilage regeneration; however, considerable heterogeneity was observed regarding MSC source, preparation methods, and outcome measures. MSCs show promise in the treatment of knee cartilage defects. Nonetheless, due to methodological differences and limited high-quality evidence, no standardized clinical protocol can yet be recommended. Further research is needed to establish consensus and guide clinical applications.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20241426"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Listening to the bats of Carajás: Bioacoustics in a mosaic of forests, savannas, and industrial mining in the Brazilian Amazonia.","authors":"Lidiane Gomes, Enrico Bernard","doi":"10.1590/0001-3765202520240994","DOIUrl":"10.1590/0001-3765202520240994","url":null,"abstract":"<p><p>Bats emit echolocation calls for orientation, foraging, and social interactions. These calls are mostly species-specific, making them reliable for inventories and assessing habitat use - characteristics particularly useful in large, species-rich, but poorly sampled areas. This is the case of Carajás, in Brazilian Amazonia, a mosaic of cave-rich dense forests and unique metalophilous savannas (known as canga), harboring a rich bat fauna alongside industrial iron ore mining, underscoring the need to preserve biodiversity. We used bioacoustics (142,000 minutes of recording) to inventory bats at 61 points in Carajás between 2021 and 2023, and identified 43 sonotypes of seven bat families, including species rarely recorded with capture nets. Eleven species were recorded for the first time in Carajás. Species richness varied among habitats - but cangas had greater richness stability and a more distinct species composition. All areas with imminent mining had high bat richness. Richness in a post-mined area increased, possibly indicating resilience of some species. By providing a reference sound library for bats in Carajás, we proved the usefulness of biacoustics to improve the environmental licensing processes involving mining in biodiversity-rich areas, useful not only for Amazonia but also for other tropical habitats with high bat species richness.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20240994"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcio Quara DE C Santos, Flávia Dayane F Farias, Paulo Henrique R Aride, Adriano T Oliveira
{"title":"Morphology and morphometry of blood cells of two species of freshwater stingrays (Chondrichthyes: Potamotrygoninae) from the lower Solimões river, Amazon.","authors":"Marcio Quara DE C Santos, Flávia Dayane F Farias, Paulo Henrique R Aride, Adriano T Oliveira","doi":"10.1590/0001-3765202520241149","DOIUrl":"10.1590/0001-3765202520241149","url":null,"abstract":"<p><p>Cytomorphological evaluation of peripheral blood provides information about the health status of animals, in addition to being indicators of environmental contamination. However, reference data regarding the size and shape of elasmobranch blood cells is limited. This work aimed to determine the morphological and morphometric of Potamotrygon motoro and Potamotrygon orbignyi blood cells. The stingrays were captured in white water environments in the lower Solimões River region, state of Amazonas, Brazil. Blood was obtained through puncture of the branchial artery using syringes with 10% EDTA. Morphological and morphometric analyses of the cells were carried out on blood samples stained with May Grunwald-Giemsa-Wright. Erythrocytes, erythroblasts (immature erythrocytes), thrombocytes, lymphocytes, monocytes, heterophils, eosinophils and basophils were identified in the blood of both species. No evidence of erythrocyte abnormalities was found, and the blood cell's morphological characteristics were similar to those described for other species of freshwater stingrays. Despite the identical shape, the size of erythrocytes, monocytes and heterophils were significantly different between the stingray species analyzed. The information obtained in this study will assist in developing biomarkers of aquatic contamination and contribute to future research on the clinical diagnosis and conservation of freshwater stingrays.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20241149"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flávia Dayane F Farias, Paulo Henrique R Aride, Ariany R S Liebl, Maiko W S Ribeiro, Tiago C Nóbrega, Adriano T DE Oliveira
{"title":"Hematological parameters and plasma biochemistry of tambaqui (Colossoma macropomum) from fish farms in the Amazon Region.","authors":"Flávia Dayane F Farias, Paulo Henrique R Aride, Ariany R S Liebl, Maiko W S Ribeiro, Tiago C Nóbrega, Adriano T DE Oliveira","doi":"10.1590/0001-3765202520241449","DOIUrl":"10.1590/0001-3765202520241449","url":null,"abstract":"<p><p>The tambaqui Colossoma macropomum is the main species of edible fish originating from fish farming in the Amazon region. This study aimed to determine and compare the blood physiology of tambaqui from fish farms in municipalities in the Metropolitan Region of Manaus, Amazonas, Brazil. Two fish farms were sampled in a semi-excavated pond-type breeding system in the five investigated towns. There were notable variations between Iranduba and Novo Airão in the erythrogram's hematocrit, hemoglobin concentration, and erythrocytes, indicating signs of anemia and dehydration. Fish from Novo Airão and Iranduba have low levels of plasma biochemistry. Low levels of fatty molecules were detected in Manacapuru tambaqui. The leukogram and thrombogram assessed the similarities among tambaqui from different farms and communities and showed significant intraspecific variation. However, as seen by the elevated blood levels of triglycerides and cholesterol, fish from Manacapuru are fed an unsuitable diet. Determining the hematological parameters of C. macropomum tambaqui, the primary native species produced in Brazil, is crucial for defining the boundaries between healthy and diseased conditions for this significant aquaculture species. Supporting rural agricultural regulatory organizations, tambaqui producers, and researchers.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20241449"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo S Magalhães, Maria Conceição L Amazonas, Luisa Maria Diele-Viegas
{"title":"Dismantling Environmental Protections in Brazil: How a New Law Disproportionately Harms Indigenous Peoples and Accelerates Biodiversity Loss.","authors":"Ricardo S Magalhães, Maria Conceição L Amazonas, Luisa Maria Diele-Viegas","doi":"10.1590/0001-3765202520250663","DOIUrl":"10.1590/0001-3765202520250663","url":null,"abstract":"","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 4","pages":"e20250663"},"PeriodicalIF":1.1,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo Junio R Barros, Andreia Laura P Rodrigues, Camila Dourado, Luciana Maria Silva, Jonas Enrique A Perales, Sandra Lauton-Santos, Andreia Barroso, Jader S Cruz
{"title":"MACL-1 Breast Cancer Secretome Reprograms Fibroblasts to Enhance Inflammation and Tumor Progression.","authors":"Rodrigo Junio R Barros, Andreia Laura P Rodrigues, Camila Dourado, Luciana Maria Silva, Jonas Enrique A Perales, Sandra Lauton-Santos, Andreia Barroso, Jader S Cruz","doi":"10.1590/0001-3765202520250146","DOIUrl":"https://doi.org/10.1590/0001-3765202520250146","url":null,"abstract":"<p><p>Tumor-secreted factors reprogram the stromal microenvironment to facilitate cancer progression. This study investigates the effects of the MACL-1 breast cancer cell secretome on CCD19-Lu fibroblasts. Fibroblasts treated with the MACL-1 secretome exhibited increased proliferation, altered morphology, and upregulated expression of vimentin, NFκB, and fibroblast-activating protein, indicative of an inflammatory, activated phenotype. Additionally, elevated mitochondrial superoxide levels and an enrichment of proteases were detected in the secretome, but not in corresponding cell lysates. These findings suggest that the MACL-1 secretome promotes fibroblast activation and inflammation, underscoring its potential role in tumor-stroma interactions and breast cancer progression.</p>","PeriodicalId":7776,"journal":{"name":"Anais da Academia Brasileira de Ciencias","volume":"97 3","pages":"e20250146"},"PeriodicalIF":1.1,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144788072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}