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Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR最新文献

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[Effect of physical load and brief monotherapy with obsidan on the characteristics of beta 2-adrenoreceptors of intact lymphocytes in patients with hypertension]. [体力负荷和短时间单药奥比丹对高血压患者完整淋巴细胞β 2-肾上腺素受体特征的影响]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
E V Parfenova, E Nauman, I L Korichneva, Iu I Suvorov, N A Aripova
{"title":"[Effect of physical load and brief monotherapy with obsidan on the characteristics of beta 2-adrenoreceptors of intact lymphocytes in patients with hypertension].","authors":"E V Parfenova,&nbsp;E Nauman,&nbsp;I L Korichneva,&nbsp;Iu I Suvorov,&nbsp;N A Aripova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphocytes beta 2-receptor density (LBRD) was studied by binding with 125ICYP in 18 male patients with mild/moderate essential hypertension (EH) before and after propranolol monotherapy. In 5 of these patients LBRD was determined before and after dynamic exercise also. Propranolol therapy evoked different changes in LBRD in patients with EH. According to these results, all the patients were divided into 2 groups: the patients who respond to propranolol administration by an increase in the LBRD were attributed to the 1 group. If the LBRD decreased after propranolol, the patients were attributed to the 2 group. Propranolol had pronounced hypotensive effect in the 2 group and no hypotensive effect in the 1 group. Heart rate was significantly higher initially and decreased significantly more after treatment in the 2 group. In this group initial values of LBRD were significantly higher than in the 1 group. Exercise produced different changes in LBRD, which correlated with the changes produced by propranolol treatment. The positive correlations were found between LBRD and left ventricular myocardial mass and interventricular septum thickness. The data obtained indicate that LBRD is regulated in a qualitatively different manner in the two groups of patients with EH which appears to be related to baseline renin or perhaps catecholamine levels.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 1","pages":"60-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13978126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Calcium antagonists: the mechanism of their action and aspects of their clinical use in cardiac insufficiency]. [钙拮抗剂:其作用机制及其在心功能不全中的临床应用]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
V Iu Mareev, A Khosseĭn
{"title":"[Calcium antagonists: the mechanism of their action and aspects of their clinical use in cardiac insufficiency].","authors":"V Iu Mareev,&nbsp;A Khosseĭn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 1","pages":"118-25"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14174459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of lipostabil on cholesterol levels in atherosclerotic plaques of the human aorta and the aggregative capacity of thrombocytes (in vitro study)]. [脂后他比尔对人主动脉动脉粥样硬化斑块中胆固醇水平和血小板聚集能力的影响(体外研究)]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
Kh A Khashimov, F Okur, A N Orekhov, Kh A Kurdanov, V Tertov
{"title":"[Effect of lipostabil on cholesterol levels in atherosclerotic plaques of the human aorta and the aggregative capacity of thrombocytes (in vitro study)].","authors":"Kh A Khashimov,&nbsp;F Okur,&nbsp;A N Orekhov,&nbsp;Kh A Kurdanov,&nbsp;V Tertov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was found out that lipostabil induced decrease in cholesterol contents in both organ and primary culture of human aorta atherosclerotic plaques. This phenomenon was caused by the effect of lipostabil on cellular output of cholesterol. The study of concentration dependence showed that the cholesterol-decreasing effect of lipostabil was maximal at its concentration in the medium over 250 microliter/ml. At such concentration lipostabil had no significant effect on the blood rheology and inhibited to a great extent platelet aggregation induced by phospholipid platelet activating factor and by some other agents.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 1","pages":"95-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14527534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Correction (in vitro) of proteinase inhibitor balance in the blood of patients after cardiosurgical interventions]. [心脏手术干预后患者血液中蛋白酶抑制剂平衡的(体外)校正]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
O G Ogloblina, G E Bazhenova, L A Belova, O P Shevchenko, A A Dmitriev
{"title":"[Correction (in vitro) of proteinase inhibitor balance in the blood of patients after cardiosurgical interventions].","authors":"O G Ogloblina,&nbsp;G E Bazhenova,&nbsp;L A Belova,&nbsp;O P Shevchenko,&nbsp;A A Dmitriev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Proteinase-inhibitor balance in human plasma before and after artificial blood circulation was examined. It was shown that trypsinlike and chemotrypsinlike proteinases activities after this procedure were 1.6 and 2.8 times higher and antitryptic activity 1.2 times lower than in the same patients before the procedure. The 40-50% decrease of proteinase activity in human plasma after artificial blood circulation was observed as a result of in vitro plasmasorption on immobilized human urinary trypsin inhibitor.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 1","pages":"102-4"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14525162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Structure of the cholinergic nerve plexuses of the heart and their function in sudden cardiac death]. 心脏胆碱能神经丛的结构及其在心源性猝死中的作用
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
N I Zhuchkova
{"title":"[Structure of the cholinergic nerve plexuses of the heart and their function in sudden cardiac death].","authors":"N I Zhuchkova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>54 hearts of men aged 30-60 were studied histochemically. The control consisted of 12 hearts of persons who died of cerebral injury. 42 persons died suddenly by fresh myocardial infarction, small-focal cardiosclerosis, postinfarction cardiosclerosis or alcohol cardiomyopathy. The density of nervous plexus was higher in the right atrium than in the left one. Right and left ventricle differed in the same way. In older persons, especially those who died suddenly, density of myocardial cholinergic nervous plexus (especially perivasal) decreased which was associated with development of perivasal fibrosis characteristic for neurotomy of perivasal plexus. Density of cardiac cholinergic plexus differed in various myocardial pathologies. It was the highest in sudden death in patients with small-focal cardiosclerosis and the lowest in sudden death in patients with fresh myocardial infarction.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 2","pages":"54-8"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14362510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cardiomyopathies: current aspects of the problem]. [心肌病:问题的当前方面]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
N M Mukharliamov
{"title":"[Cardiomyopathies: current aspects of the problem].","authors":"N M Mukharliamov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 2","pages":"3-6"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14363405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Mechanisms of the anomalous activity of the Purkinje fibers in the late stage of experimental myocardial infarct in dogs]. [犬实验性心肌梗死晚期浦肯野纤维异常活动的机制]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
E P Aniukhovskiĭ, G G Beloshapko, L V Rozenshtraukh
{"title":"[Mechanisms of the anomalous activity of the Purkinje fibers in the late stage of experimental myocardial infarct in dogs].","authors":"E P Aniukhovskiĭ,&nbsp;G G Beloshapko,&nbsp;L V Rozenshtraukh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The anomalously active (AA) subendocardial Purkinje's fibers (PF) in the ischemic zone 24 hours after occlusion of the left descending coronary artery (LDCA) in dogs are proposed to be divided into 2 groups according to their reaction to the changes in the ionic composition of perfusion solution. The AAPF frequency in the first group decreased by increase in [Ca2+]o, increased by fall in [Ca2+]o and was proportional to [Na+]o. In the second group AAPF frequency rose under actions increasing [Ca2+]i (increase in [Ca+]o, decrease in [Na+]o), and fell under actions reducing [Ca2+]i (decrease in [Ca2+]o, increase in [Na+]o). After short-term (10 s) high frequency stimulation the AAPF frequency in the group I fibers either remained unchanged or insignificant transitory slowing down was registered. In the group II fibers the AA frequency after high frequency stimulation either remained unchanged or insignificant transitory elevation was observed. The anomalous activity in the group I fibers could be blocked by tetrodotoxin, while verapamil was practically ineffective. In the second group anomalous activity was blocked by both drugs. We conclude thus that one day after the occlusion of LDCA in the ischemic zone PF with anomalous activity caused by anomalous automaticity as well as by trigger mechanism may be present. The pacemaker current inducing anomalous automaticity is possibly caused by Na+ intake through ischemically modified natrium channels.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 2","pages":"35-41"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14363406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Videodensitometric analysis of the characteristics of coronary blood flow using computed digital angiography in patients with ischemic heart disease]. [缺血性心脏病患者冠脉血流特征的计算机数字血管造影视频密度分析]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
A P Savchenko, E V Pomerantsev, S A Abugov, M L Blank
{"title":"[Videodensitometric analysis of the characteristics of coronary blood flow using computed digital angiography in patients with ischemic heart disease].","authors":"A P Savchenko,&nbsp;E V Pomerantsev,&nbsp;S A Abugov,&nbsp;M L Blank","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Videodensitometry with following computer analysis of the image obtained by digital subtraction angiography is a method allowing an objective quantitative evaluation of the volume rate of coronary and myocardial blood flow. The moment of contrast appearance in the myocardium as well as the moment of peak concentration, half elimination period and contrast passage period should be taken into consideration. These parametres were significantly increased in patients with obstruction of the left descending artery (LDA) compared to control. At the same time coronary blood flow indexes in patients with advanced stenosis of LDA did not differ significantly from those in patients with normal LDA which could be associated with unaltered coronary and myocardial hemodynamics at rest.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 2","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14201158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A multifactorial evaluation scale of psychosocial changes in patients with hypertension]. [高血压患者心理社会变化的多因素评估量表]。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
V P Zaĭtsev, T A Aĭvazian
{"title":"[A multifactorial evaluation scale of psychosocial changes in patients with hypertension].","authors":"V P Zaĭtsev,&nbsp;T A Aĭvazian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A simple and time-spending method permitting formalized evaluation of peculiarities of the personality, psychic status, social-psychologic peculiarities and attitude to treatment of patients with essential hypertension has been developed. The scale is proved to have high discrimination value, theoretic validity and validity according to the outer criteria, as well as sufficient reliability and sensitivity. The method may be used for scientific purposes as well as in practice for evaluation of psychosocial status of patients with essential hypertension, its dynamics in the process of treatment, choice of differential medical tactics, prognosis and assessment of the intervention effect.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 1","pages":"81-6"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14527533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hypotensive effect of dinitrosyl iron complexes in experiments on waking animals]. 二硝基铁配合物在清醒动物实验中的降压作用。
Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR Pub Date : 1988-01-01
M E Galagan, E V Oranovskaia, P I Mordvintsev, O S Medvedev, A F Vanin
{"title":"[Hypotensive effect of dinitrosyl iron complexes in experiments on waking animals].","authors":"M E Galagan,&nbsp;E V Oranovskaia,&nbsp;P I Mordvintsev,&nbsp;O S Medvedev,&nbsp;A F Vanin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Changes in arterial pressure evoked by dinitrosyl iron complexes (DNIC) were studied in conscious normotensive (Wistar) and spontaneously hypertensive (SHR) rats. Doses from 1 to 10 mcM/kg of DNIC evoked dose-dependent decrease in blood pressure for two hours. SHR rats were more sensitive to the effect of the drug than normotensive Wistar rats. Long-lasting effects of the drug depended on the NO-stores, which were DNIC with paired RS-(-)groups of proteins. These complexes measured with EPR method were formed as a result of Fe(NO)2 groups transfer from injected low molecular weight DNIC to protein RS-(-)groups.</p>","PeriodicalId":77680,"journal":{"name":"Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR","volume":"11 2","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13991068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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