[Structure of the cholinergic nerve plexuses of the heart and their function in sudden cardiac death].

N I Zhuchkova
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引用次数: 0

Abstract

54 hearts of men aged 30-60 were studied histochemically. The control consisted of 12 hearts of persons who died of cerebral injury. 42 persons died suddenly by fresh myocardial infarction, small-focal cardiosclerosis, postinfarction cardiosclerosis or alcohol cardiomyopathy. The density of nervous plexus was higher in the right atrium than in the left one. Right and left ventricle differed in the same way. In older persons, especially those who died suddenly, density of myocardial cholinergic nervous plexus (especially perivasal) decreased which was associated with development of perivasal fibrosis characteristic for neurotomy of perivasal plexus. Density of cardiac cholinergic plexus differed in various myocardial pathologies. It was the highest in sudden death in patients with small-focal cardiosclerosis and the lowest in sudden death in patients with fresh myocardial infarction.

心脏胆碱能神经丛的结构及其在心源性猝死中的作用
对54例30-60岁男性的心脏进行了组织化学研究。对照组包括12个死于脑损伤的人的心脏。42例突发新鲜心肌梗死、小灶性心肌硬化、梗死后心肌硬化或酒精性心肌病死亡。右心房神经丛密度高于左心房。右心室和左心室也有同样的区别。在老年人中,特别是那些突然死亡的人,心肌胆碱能神经丛(特别是血管周围)的密度降低,这与血管周围神经丛神经切断术的血管周围纤维化的发展有关。心肌胆碱能丛密度在不同的心肌病理中存在差异。小灶性心脏硬化患者猝死率最高,新发心肌梗死患者猝死率最低。
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